Bus Milan to Siena - Compare all Companies

Compare all timetables for the bus from Milan to Siena

Here is a selection of the cheapest bus trips from the schedule from Milan to Siena from various bus operators like FlixBus or Itabus for the next days.

today

$17

tomorrow

$12

Friday

Saturday

$13

Sunday

$12

Monday

$13

Tuesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 1/28/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 1/28/2026 4:20:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 40m
Itabus	6h 30m	10:40 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$20	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 1/28/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 5:10:00 AM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 6h 30m
Itabus	5h 40m	11:30 PM	Milan	San Donato Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$20	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 1/28/2026 11:30:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 5:10:00 AM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 5h 40m
Itabus	12h 20m	10:30 PM	Milan	Lampugnano Bus Station	10:50 AM	Siena	Train Station	Economy	$56	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 1/28/2026 10:30:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 10:50:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 12h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 45m	3:30 PM	Milan	Lampugnano Bus Station	9:15 PM	Siena	Train Station	Economy	$12	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 1/29/2026 3:30:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 9:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 5h 45m
FlixBus	7h 40m	12:00 PM	Milan	Lampugnano Bus Station	7:40 PM	Siena	Train Station	Economy	$14	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 1/29/2026 12:00:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 7:40:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 7h 40m
FlixBus	5h 50m	12:25 PM	Milan	Lampugnano Bus Station	6:15 PM	Siena	Train Station	Economy	$14	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 1/29/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 6:15:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 50m
FlixBus	5h 35m	2:25 PM	Milan	San Donato Bus Station	8:00 PM	Siena	Train Station	Economy	$14	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 1/29/2026 2:25:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 8:00:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 35m
FlixBus	6h 0m	4:20 PM	Milan	Lampugnano Bus Station	10:20 PM	Siena	Train Station	Economy	$17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 1/29/2026 4:20:00 PM to Train Station, Siena (Italy) arriving at 1/29/2026 10:20:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 6h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 45m	3:30 PM	Milan	Lampugnano Bus Station	9:15 PM	Siena	Train Station	Economy	$13	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 1/31/2026 3:30:00 PM to Train Station, Siena (Italy) arriving at 1/31/2026 9:15:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 5h 45m
FlixBus	6h 15m	6:15 AM	Milan	Lampugnano Bus Station	12:30 PM	Siena	Train Station	Economy	$14	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 1/31/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 1/31/2026 12:30:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 6h 15m
FlixBus	5h 50m	12:25 PM	Milan	Lampugnano Bus Station	6:15 PM	Siena	Train Station	Economy	$14	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 1/31/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 1/31/2026 6:15:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 50m
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$17	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 1/31/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 1/31/2026 4:20:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 40m
Itabus	6h 30m	10:40 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 1/31/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 2/1/2026 5:10:00 AM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 55m	12:35 AM	Milan	Lampugnano Bus Station	5:30 AM	Siena	Train Station	Economy	$12	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/1/2026 12:35:00 AM to Train Station, Siena (Italy) arriving at 2/1/2026 5:30:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 4h 55m
FlixBus	5h 50m	12:25 PM	Milan	Lampugnano Bus Station	6:15 PM	Siena	Train Station	Economy	$12	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/1/2026 12:25:00 PM to Train Station, Siena (Italy) arriving at 2/1/2026 6:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 5h 50m
FlixBus	4h 20m	1:10 AM	Milan	San Donato Bus Station	5:30 AM	Siena	Train Station	Economy	$12	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 2/1/2026 1:10:00 AM to Train Station, Siena (Italy) arriving at 2/1/2026 5:30:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 4h 20m
Itabus	6h 30m	10:40 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Train Station	Premium Economy	$19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/1/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 2/2/2026 5:10:00 AM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 30m
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/1/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 2/1/2026 4:20:00 PM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 5h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 15m	6:15 AM	Milan	Lampugnano Bus Station	12:30 PM	Siena	Train Station	Economy	$13	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/2/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 2/2/2026 12:30:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 6h 15m
FlixBus	7h 25m	8:15 AM	Milan	Lampugnano Bus Station	3:40 PM	Siena	Train Station	Economy	$13	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/2/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 2/2/2026 3:40:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 7h 25m
FlixBus	6h 35m	8:20 AM	Milan	Lampugnano Bus Station	2:55 PM	Siena	Train Station	Economy	$13	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 2/2/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 2/2/2026 2:55:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 6h 35m
Itabus	6h 30m	10:40 PM	Milan	Lampugnano Bus Station	5:10 AM	Siena	Piazza Antonio Gramsci	Economy	$22	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/2/2026 10:40:00 PM to Piazza Antonio Gramsci, Siena (Italy) arriving at 2/3/2026 5:10:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 6h 30m
Itabus	5h 40m	10:40 AM	Milan	Lampugnano Bus Station	4:20 PM	Siena	Train Station	Premium Economy	$28	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 2/2/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 2/2/2026 4:20:00 PM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 5h 40m

Best Price Offer: The price for the cheapest bus from Milan to Siena is $11 on 1/25/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milan and Siena

See here how frequent the connections between Milan and Siena are, during different times and days of the week.

Monday is the busiest day, with more than 29 daily buses from Milan to Siena. Wednesday has instead the fewest connections, with only 7 daily coaches between Milan and Siena.

The busiest time of the day is the Afternoon, with 33 buses from Milan to Siena, while Night sees the fewest connections between Milan and Siena, with 10 offers.

Facts about the bus from Milan to Siena

Compare all providers like FlixBus and Itabus that travel 18 times every day by bus from Milan to Siena in one click! Book your bus ticket from Milan to Siena starting from $11!

Cheapest Bus	$11
Fastest Bus	4h 20m
Earliest Bus	10:40 AM
Latest Bus	11:30 PM
Daily Bus Routes	18 Ø
Distance	182.3 miles
Bus Companies	FlixBus and Itabus

Cheapest bus connections from Milan to Siena

Every day, 18 buses from 2 bus companies leave Milan for Siena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/28/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/25

Monday 01/26

Tuesday 01/27

Wednesday 01/28

$11

Thursday 01/29

$12

Friday 01/30

Saturday 01/31

$11

Sunday 02/01

$12

Monday 02/02

$13

Tuesday 02/03

Wednesday 02/04

$12

Thursday 02/05

$11

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

Sunday 02/15

Monday 02/16

Tuesday 02/17

Wednesday 02/18

Thursday 02/19

Friday 02/20

Saturday 02/21

The cheapest time to travel from Milan to Siena

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Siena, for the next 30 days.

With a price starting from $11, Wednesday is the cheapest day for a bus from Milan to Siena. Monday instead is the most expensive day with prices starting from $13.

Night is the cheapest day time for bus tickets from Milan to Siena, with $11. Evening is the most expensive time of the day with prices starting from $19.

How to save money travelling from Milan to Siena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Siena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Siena are also emptier.

All bus stations and stops in Milan and Siena

In the map below, you can see where to find all bus stations in Milan and Siena.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Siena? Compare all modes of transports from Milan to Siena.

Service and Comfort on the bus from Milan to Siena

Want to know which seat classes are available on the buses from Milan to Siena? Or which bus companies serve the route Milan to Siena? Below you will find answers to your questions.

FAQs about the Milan to Siena bus

How much does a Milan Siena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $11 and takes 5h 45m to reach Siena. Compare offers to save money!

How much could I save by comparing buses from Milan to Siena?

This route is offered by 2 companies with a range of ticket prices between $11 and $57. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Siena.

On average, how many connections are available from Milan to Siena each day?

Every day, the Milan to Siena bus route is served by approximately 18 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Siena take?

The fastest bus from Milan to Siena is offered by FlixBus and takes 4h 20m. Bus tickets for this connection cost $34. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Siena?

The earliest bus arriving in Siena from Milan starts at 10:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Siena?

The latest bus trip departing from Milan for Siena starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Siena route?

When traveling by bus from Milan to Siena, passengers can travel with FlixBus and Itabus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Siena?

You can check all the direct connections between Milan and Siena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Itabus.

What can I take with me on the Milan to Siena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Siena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Siena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Siena on your planned travel date.

How does CheckMyBus find the best bus deals from Milan to Siena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 18 daily trips between Milan and Siena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Siena?

Prices and availability for 18 trips between Milan and Siena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Siena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Siena

Here’s an overview of the most popular bus routes to Milan and to Siena. Simply click on the connection of your choice, and you will find all the details about your bus route!