Bus from Lyon to Milan from $22

Compare all the bus companies and find the best price with CheckMyBus
1
Search accommodation with Booking.com
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Lyon to Milan

Here is a selection of the cheapest bus trips from the schedule from Lyon to Milan from various bus operators like BlaBlaCar Bus, FlixBus or Itabus for the next days.

today
from $41
tomorrow
from $33
Tuesday
from $27
Wednesday
from $24
Thursday
from $22
Friday
from $41
Saturday
from $32

Cheapest bus trips today

Prices are for one way and one person
  • BlaBlaCar Bus
    6h 16m
    0
    11:59 PM
    Lyon
    Perrache Train Station
    6:15 AM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $41
  • BlaBlaCar Bus
    6h 16m
    0
    11:59 PM
    Lyon
    Perrache Bus Stop
    6:15 AM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $41
  • Itabus
    6h 35m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    3:50 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Economy
    $48
  • FlixBus
    6h 20m
    0
    8:05 AM
    Lyon
    Perrache Bus Stop
    2:25 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    6h 35m
    0
    10:45 AM
    Lyon
    Perrache Bus Stop
    5:20 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $53
  • Did you know that if you travel from Lyon to Milan via Chambery, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      9h 20m
      0
      7:10 AM
      Lyon
      Perrache Bus Stop
      10:00 AM
      Chambery
      Bus Station
      0
      FlixBus
      Economy
      $12
      • Waiting Time 1h 30m
    • Busbud
      5h 0m
      0
      11:30 AM
      Chambery
      Bus Station
      4:30 PM
      Milan
      Lampugnano Bus Station
      0
      Busbud
      Economy
      $20
    Travel time is 3h 4m longer, but you will save $9

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Itabus
    6h 35m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    3:50 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $33
  • Itabus
    6h 50m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    10:20 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $33
  • BlaBlaCar Bus
    7h 5m
    0
    7:00 AM
    Lyon
    Perrache Train Station
    2:05 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $35
  • BlaBlaCar Bus
    7h 45m
    0
    9:45 AM
    Lyon
    Perrache Train Station
    5:30 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $35
  • FlixBus
    6h 35m
    0
    10:45 AM
    Lyon
    Perrache Bus Stop
    5:20 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $37

Cheapest bus trips Tuesday

Prices are for one way and one person
  • BlaBlaCar Bus
    6h 30m
    0
    11:30 PM
    Lyon
    Perrache Bus Stop
    6:00 AM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $27
  • BlaBlaCar Bus
    6h 15m
    0
    1:45 AM
    Lyon
    Perrache Bus Stop
    8:00 AM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $35
  • Itabus
    6h 50m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    10:20 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $35
  • FlixBus
    6h 5m
    0
    3:25 AM
    Lyon
    Perrache Bus Stop
    9:30 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $37
  • FlixBus
    7h 0m
    0
    2:55 PM
    Lyon
    Perrache Bus Stop
    9:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $37

Cheapest bus trips Wednesday

Prices are for one way and one person
  • BlaBlaCar Bus
    6h 55m
    0
    5:10 AM
    Lyon
    Perrache Train Station
    12:05 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $24
  • BlaBlaCar Bus
    6h 45m
    0
    2:35 PM
    Lyon
    Perrache Train Station
    9:20 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $24
  • Itabus
    6h 35m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    3:50 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $33
  • Itabus
    6h 50m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    10:20 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $33
  • FlixBus
    6h 35m
    0
    10:45 AM
    Lyon
    Perrache Bus Stop
    5:20 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $36

Cheapest bus trips Thursday

Prices are for one way and one person
  • Itabus
    6h 50m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    10:20 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $22
  • BlaBlaCar Bus
    6h 55m
    0
    5:10 AM
    Lyon
    Perrache Bus Stop
    12:05 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $27
  • BlaBlaCar Bus
    6h 45m
    0
    2:35 PM
    Lyon
    Perrache Train Station
    9:20 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $27
  • FlixBus
    6h 35m
    0
    4:00 PM
    Lyon
    Perrache Bus Stop
    10:35 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $30
  • Itabus
    6h 35m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    3:50 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $35

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    6h 35m
    0
    4:00 PM
    Lyon
    Perrache Bus Stop
    10:35 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $41
  • BlaBlaCar Bus
    7h 45m
    0
    11:00 AM
    Lyon
    Perrache Train Station
    6:45 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $41
  • BlaBlaCar Bus
    6h 45m
    0
    2:35 PM
    Lyon
    Perrache Train Station
    9:20 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $41
  • Itabus
    6h 50m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    10:20 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $41
  • FlixBus
    7h 5m
    0
    6:15 AM
    Lyon
    Perrache Bus Stop
    1:20 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $48
  • Did you know that if you travel from Lyon to Milan via Chambery, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      9h 20m
      0
      7:10 AM
      Lyon
      Perrache Bus Stop
      10:00 AM
      Chambery
      Bus Station
      0
      FlixBus
      Economy
      $12
      • Waiting Time 1h 30m
    • Busbud
      5h 0m
      0
      11:30 AM
      Chambery
      Bus Station
      4:30 PM
      Milan
      Lampugnano Bus Station
      0
      Busbud
      Economy
      $20
    Travel time is 2h 45m longer, but you will save $9

Cheapest bus trips Saturday

Prices are for one way and one person
  • Union Ivkoni
    6h 30m
    0
    10:00 AM
    Lyon
    Perrache Bus Stop
    4:30 PM
    Milan
    Lampugnano Bus Station
    0
    Union Ivkoni
    Economy
    $32
  • Itabus
    6h 50m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    10:20 PM
    Milan
    Lampugnano Bus Station
    0
    Itabus
    Premium Economy
    $35
  • BlaBlaCar Bus
    6h 45m
    0
    2:35 PM
    Lyon
    Perrache Bus Stop
    9:20 PM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $41
  • BlaBlaCar Bus
    6h 30m
    0
    11:30 PM
    Lyon
    Perrache Bus Stop
    6:00 AM
    Milan
    Lampugnano Bus Station
    0
    BlaBlaCar Bus
    Economy
    $41
  • FlixBus
    6h 35m
    0
    4:00 PM
    Lyon
    Perrache Bus Stop
    10:35 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $42

Frequency of bus connections between Lyon and Milan

See here how frequent the connections between Lyon and Milan are, during different times and days of the week.
Monday is the busiest day, with more than 33 daily buses from Lyon to Milan. Sunday has instead the fewest connections, with only 28 daily coaches between Lyon and Milan.
The busiest time of the day is the Morning, with 97 buses from Lyon to Milan, while Night sees the fewest connections between Lyon and Milan, with 28 offers.

Facts about the bus from Lyon to Milan

Compare all providers like BlaBlaCar Bus, FlixBus and Itabus that travel 31 times every day by bus from Lyon to Milan in one click! Book your bus ticket from Lyon to Milan starting from $22!

Cheapest Bus $22
Fastest Bus 6h 5m
Earliest Bus 1:15 AM
Latest Bus 11:59 PM
Daily Bus Routes 31 Ø
Distance 211.3 miles
Bus Companies BlaBlaCar Bus, FlixBus, Itabus and Union Ivkoni

Cheapest bus connections from Lyon to Milan

Every day, 31 buses from 4 bus companies leave Lyon for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/30/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/29
$41
Monday 06/30
$27
Tuesday 07/01
$35
Wednesday 07/02
$35
Thursday 07/03
$22
Friday 07/04
$41
Saturday 07/05
$35
Sunday 07/06
$33
Monday 07/07
$35
Tuesday 07/08
$29
Wednesday 07/09
$27
Thursday 07/10
$41
Friday 07/11
$41
Saturday 07/12
$39
Sunday 07/13
$41
Monday 07/14
$35
Tuesday 07/15
$29
Wednesday 07/16
$29
Thursday 07/17
$27
Friday 07/18
$35
Saturday 07/19
$41
Sunday 07/20
$41
Monday 07/21
$41
Tuesday 07/22
$29
Wednesday 07/23
$27
Thursday 07/24
$29
Friday 07/25
$27
Saturday 07/26

The cheapest time to travel from Lyon to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Milan, for the next 30 days.
With a price starting from $22, Thursday is the cheapest day for a bus from Lyon to Milan. Sunday instead is the most expensive day with prices starting from $41.
Afternoon is the cheapest day time for bus tickets from Lyon to Milan, with $22. Morning is the most expensive time of the day with prices starting from $32.

How to save money travelling from Lyon to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lyon to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Milan are also emptier.

Beloved bus companies from Lyon to Milan

These are the most booked bus companies between Lyon to Milan from our users.

FlixBus from Lyon to Milan

FlixBus

Here you will find the key facts about the FlixBus bus route Lyon to Milan:

Cheapest Price $30
Fastest Bus 6h 5m
Earliest Bus 1:15 AM
Last Bus 11:00 PM
Daily Connections 8 Ø
Found on 6/28/2025

BlaBlaCar Bus from Lyon to Milan

BlaBlaCar Bus

Here you will find the key facts about the BlaBlaCar Bus bus route Lyon to Milan:

Cheapest Price $24
Fastest Bus 6h 15m
Earliest Bus 7:00 AM
Last Bus 11:59 PM
Daily Connections 16 Ø
Found on 6/28/2025

Union Ivkoni from Lyon to Milan

Union Ivkoni

Here you will find the key facts about the Union Ivkoni bus route Lyon to Milan:

Cheapest Price $32
Fastest Bus 5h 30m
Earliest Bus 10:00 AM
Last Bus 10:00 AM
Daily Connections 1 Ø
Found on 6/28/2025

Latest reviews for bus companies on the route Lyon - Milan

Union Ivkoni
crepieux ruben, 3/18/2025

chauffeur parfaitement capable de conduire, trajets trés agréable malgré ma séparation avec mon camarade en début de trajets. trés bonne conduite.

All bus stations and stops in Lyon and Milan

In the map below, you can see where to find all bus stations in Lyon and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Lyon to Milan? Compare all modes of transports from Lyon to Milan.

Service and Comfort on the bus from Lyon to Milan

Want to know which seat classes are available on the buses from Lyon to Milan? Or which bus companies serve the route Lyon to Milan? Below you will find answers to your questions.

FAQs about the Lyon to Milan bus

How much does a Lyon Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $22 and takes 6h 50m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Lyon to Milan?

This route is offered by 4 companies with a range of ticket prices between $22 and $88. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Lyon to Milan each day?

Every day, the Lyon to Milan bus route is served by approximately 31 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lyon to Milan take?

The fastest bus from Lyon to Milan is offered by FlixBus and takes 6h 5m. Bus tickets for this connection cost $53. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lyon to Milan?

The earliest bus arriving in Milan from Lyon starts at 1:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lyon to Milan?

The latest bus trip departing from Lyon for Milan starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lyon Milan route?

When traveling by bus from Lyon to Milan, passengers can travel with BlaBlaCar Bus, FlixBus and Itabus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lyon and Milan?

You can check all the direct connections between Lyon and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: BlaBlaCar Bus, FlixBus and Itabus.

What can I take with me on the Lyon to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lyon Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Milan on your planned travel date.

Available seat classes which are offered on the bus route Lyon to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Lyon and to Milan

Here’s an overview of the most popular bus routes to Lyon and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Tignes - Lyon Buses Tignes - Lyon
Buses Geneva to Lyon Buses Geneva to Lyon
Bus Chamonix - Lyon Bus Chamonix - Lyon
Bus to Lyon from Turin Bus to Lyon from Turin
Buses Verona to Milan Buses Verona to Milan
Bus to Milan from Lisbon Bus to Milan from Lisbon
Buses from Lugano to Milan Buses from Lugano to Milan
Bus Bologna to Milan Bus Bologna to Milan
Popular Airport Shuttles to Lyon and to Milan
CheckMyBus › Buses in France › Bus to Lyon › Bus to Milan

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.