Bus from Brussels to Lyon from $35

Compare 2 companies and find the best price with CheckMyBus
1
Search accommodation with Booking.com
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Brussels to Lyon

Here is a selection of the cheapest bus trips from the schedule from Brussels to Lyon from various bus operators like BlaBlaCar Bus or FlixBus for the next days.
today
from $43
tomorrow
from $62
Monday
from $46
Tuesday
from $46
Wednesday
from $44
Thursday
from $35
Friday
from $54

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    12h 20m
    0
    10:55 PM
    Brussels
    North Station
    11:15 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $43
  • BlaBlaCar Bus
    10h 35m
    0
    4:55 PM
    Brussels
    Midi Bus Station
    3:30 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $58
  • BlaBlaCar Bus
    10h 35m
    0
    4:55 PM
    Brussels
    Midi Bus Station
    3:30 AM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $58
  • BlaBlaCar Bus
    10h 20m
    0
    6:10 PM
    Brussels
    North Station
    4:30 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $58
  • FlixBus
    12h 5m
    0
    4:40 PM
    Brussels
    Midi Bus Station
    4:45 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $62

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    12h 20m
    0
    10:55 PM
    Brussels
    North Station
    11:15 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $62
  • BlaBlaCar Bus
    11h 45m
    0
    12:05 PM
    Brussels
    Midi Bus Station
    11:50 PM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $68
  • BlaBlaCar Bus
    10h 45m
    0
    1:30 PM
    Brussels
    Midi Bus Station
    12:15 AM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $68
  • BlaBlaCar Bus
    9h 45m
    0
    12:15 AM
    Brussels
    Midi Bus Station
    10:00 AM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $69
  • FlixBus
    10h 45m
    0
    6:00 PM
    Brussels
    North Station
    4:45 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $70

Cheapest bus trips Monday

Prices are for one way and one person
  • BlaBlaCar Bus
    10h 45m
    0
    1:30 PM
    Brussels
    Midi Bus Station
    12:15 AM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $46
  • BlaBlaCar Bus
    10h 25m
    0
    2:20 PM
    Brussels
    Midi Bus Station
    12:45 AM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $46
  • BlaBlaCar Bus
    11h 30m
    0
    7:20 AM
    Brussels
    Midi Bus Station
    6:50 PM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $48
  • FlixBus
    12h 20m
    0
    10:55 PM
    Brussels
    North Station
    11:15 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $49
  • FlixBus
    12h 5m
    0
    4:40 PM
    Brussels
    North Station
    4:45 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $55

Cheapest bus trips Tuesday

Prices are for one way and one person
  • BlaBlaCar Bus
    10h 35m
    0
    5:55 PM
    Brussels
    Midi Bus Station
    4:30 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $46
  • BlaBlaCar Bus
    10h 35m
    0
    5:55 PM
    Brussels
    Midi Bus Station
    4:30 AM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $46
  • FlixBus
    11h 45m
    0
    6:15 PM
    Brussels
    North Station
    6:00 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $51
  • BlaBlaCar Bus
    10h 10m
    0
    7:05 PM
    Brussels
    Midi Bus Station
    5:15 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $52
  • FlixBus
    13h 0m
    0
    4:15 PM
    Brussels
    North Station
    5:15 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $60

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    13h 15m
    0
    10:05 AM
    Brussels
    Midi Bus Station
    11:20 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $44
  • BlaBlaCar Bus
    11h 15m
    0
    11:30 AM
    Brussels
    Midi Bus Station
    10:45 PM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $45
  • BlaBlaCar Bus
    11h 15m
    0
    11:30 AM
    Brussels
    Midi Bus Station
    10:45 PM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $45
  • BlaBlaCar Bus
    10h 10m
    0
    7:05 PM
    Brussels
    Midi Bus Station
    5:15 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $51
  • FlixBus
    14h 15m
    0
    10:05 PM
    Brussels
    North Station
    12:20 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $56

Cheapest bus trips Thursday

Prices are for one way and one person
  • BlaBlaCar Bus
    10h 25m
    0
    2:20 PM
    Brussels
    Midi Bus Station
    12:45 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $35
  • BlaBlaCar Bus
    10h 25m
    0
    2:20 PM
    Brussels
    Midi Bus Station
    12:45 AM
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    $35
  • BlaBlaCar Bus
    11h 45m
    0
    12:05 PM
    Brussels
    Midi Bus Station
    11:50 PM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $38
  • FlixBus
    12h 20m
    0
    10:55 PM
    Brussels
    North Station
    11:15 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $45
  • FlixBus
    12h 10m
    0
    1:00 PM
    Brussels
    North Station
    1:10 AM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $48

Cheapest bus trips Friday

Prices are for one way and one person
  • BlaBlaCar Bus
    11h 30m
    0
    7:20 AM
    Brussels
    Midi Bus Station
    6:50 PM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $54
  • BlaBlaCar Bus
    10h 55m
    0
    12:55 PM
    Brussels
    Midi Bus Station
    11:50 PM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $54
  • BlaBlaCar Bus
    10h 25m
    0
    1:50 PM
    Brussels
    Midi Bus Station
    12:15 AM
    Lyon
    Perrache Train Station
    0
    BlaBlaCar Bus
    Economy
    $54
  • FlixBus
    13h 5m
    0
    7:40 AM
    Brussels
    Midi Bus Station
    8:45 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $76
  • FlixBus
    12h 45m
    0
    8:00 AM
    Brussels
    North Station
    8:45 PM
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    $76
  • Did you know that if you travel from Brussels to Lyon via Dijon, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      13h 55m
      0
      3:00 PM
      Brussels
      North Station
      1:50 AM
      Dijon
      Central Bus Station
      0
      FlixBus
      Economy
      $35
      • Waiting Time 0h 25m
    • Busbud
      2h 40m
      0
      2:15 AM
      Dijon
      Mayence Bus Stop
      4:55 AM
      Lyon
      Perrache Bus Stop
      0
      Busbud
      Economy
      $12
    Travel time is 3h 30m longer, but you will save $7

Frequency of bus connections between Brussels and Lyon

See here how frequent the connections between Brussels and Lyon are, during different times and days of the week.
Friday is the busiest day, with more than 45 daily buses from Brussels to Lyon. Tuesday has instead the fewest connections, with only 16 daily coaches between Brussels and Lyon.
The busiest time of the day is the Afternoon, with 90 buses from Brussels to Lyon, while Morning sees the fewest connections between Brussels and Lyon, with 35 offers.

Facts about the bus from Brussels to Lyon

Compare all providers like BlaBlaCar Bus and FlixBus that travel 31 times every day by bus from Brussels to Lyon in one click! Book your bus ticket from Brussels to Lyon starting from $35!

Cheapest Bus $35
Fastest Bus 9h 40m
Earliest Bus 12:15 AM
Latest Bus 10:55 PM
Daily Bus Routes 31 Ø
Distance 352.7 miles
Bus Companies BlaBlaCar Bus and FlixBus

Cheapest bus connections from Brussels to Lyon

Every day, 31 buses from 2 bus companies leave Brussels for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/21/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
Saturday 06/21
$58
Sunday 06/22
$62
Monday 06/23
$48
Tuesday 06/24
$46
Wednesday 06/25
$44
Thursday 06/26
$35
Friday 06/27
$56
Saturday 06/28
$53
Sunday 06/29
$78
Monday 06/30
$40
Tuesday 07/01
$26
Wednesday 07/02
$30
Thursday 07/03
$38
Friday 07/04
$41
Saturday 07/05
$59
Sunday 07/06
$58
Monday 07/07
$47
Tuesday 07/08
$39
Wednesday 07/09
$35
Thursday 07/10
$41
Friday 07/11
$55
Saturday 07/12

The cheapest time to travel from Brussels to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Brussels to Lyon, for the next 30 days.
With a price starting from $35, Thursday is the cheapest day for a bus from Brussels to Lyon. Sunday instead is the most expensive day with prices starting from $62.
Afternoon is the cheapest day time for bus tickets from Brussels to Lyon, with $35. Night is the most expensive time of the day with prices starting from $58.

How to save money travelling from Brussels to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Brussels to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Brussels to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Brussels to Lyon are also emptier.

Beloved bus companies from Brussels to Lyon

These are the most booked bus companies between Brussels to Lyon from our users.

BlaBlaCar Bus from Brussels to Lyon

BlaBlaCar Bus

Here you will find the key facts about the BlaBlaCar Bus bus route Brussels to Lyon:

Cheapest Price $35
Fastest Bus 9h 40m
Earliest Bus 12:15 AM
Last Bus 7:40 PM
Daily Connections 16 Ø
Found on 6/20/2025

FlixBus from Brussels to Lyon

FlixBus

Here you will find the key facts about the FlixBus bus route Brussels to Lyon:

Cheapest Price $43
Fastest Bus 10h 30m
Earliest Bus 1:30 AM
Last Bus 10:55 PM
Daily Connections 15 Ø
Found on 6/20/2025

All bus stations and stops in Brussels and Lyon

In the map below, you can see where to find all bus stations in Brussels and Lyon.

Service and Comfort on the bus from Brussels to Lyon

Want to know which seat classes are available on the buses from Brussels to Lyon? Or which bus companies serve the route Brussels to Lyon? Below you will find answers to your questions.

FAQs about the Brussels to Lyon bus

How much does a Brussels Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $35 and takes 10h 25m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Brussels to Lyon?

This route is offered by 2 companies with a range of ticket prices between $35 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Brussels to Lyon each day?

Every day, the Brussels to Lyon bus route is served by approximately 31 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Brussels to Lyon take?

The fastest bus from Brussels to Lyon is offered by BlaBlaCar Bus and takes 9h 40m. Bus tickets for this connection cost $58. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Brussels to Lyon?

The earliest bus arriving in Lyon from Brussels starts at 12:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Brussels to Lyon?

The latest bus trip departing from Brussels for Lyon starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Brussels Lyon route?

When traveling by bus from Brussels to Lyon, passengers can travel with BlaBlaCar Bus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Brussels and Lyon?

You can check all the direct connections between Brussels and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: BlaBlaCar Bus and FlixBus.

What can I take with me on the Brussels to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Brussels Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Brussels Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Brussels to Lyon on your planned travel date.

Available seat classes which are offered on the bus route Brussels to Lyon

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Brussels and to Lyon

Here’s an overview of the most popular bus routes to Brussels and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!
Liege to Brussels bus Liege to Brussels bus
Buses Milan to Brussels Buses Milan to Brussels
Paris to Brussels bus Paris to Brussels bus
Bus to Brussels from London Bus to Brussels from London
Buses Nice - Lyon Buses Nice - Lyon
Buses from Zurich to Lyon Buses from Zurich to Lyon
Buses from Strasbourg to Lyon Buses from Strasbourg to Lyon
Buses Nantes to Lyon Buses Nantes to Lyon
Popular Airport Shuttles to Brussels and to Lyon
CheckMyBus › Buses in Belgium › Bus to Brussels › Bus to Lyon

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.