What is the best way to travel from Milan to Siena?
Looking for a trip? Compare all the available Trains and Buses for the journey to Siena from Milan. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Siena from Milan?
You can get to Siena with just $9 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 4:20:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 5h 40m
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Itabus6h 30m010:40 PMMilanLampugnano Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 6/3/2026 5:10:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 30m
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Itabus5h 40m011:30 PMMilanSan Donato Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/2/2026 11:30:00 PM to Train Station, Siena (Italy) arriving at 6/3/2026 5:10:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 5h 40m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 2:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 6h 35m
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FlixBus6h 50m03:30 PMMilanLampugnano Bus Station10:20 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 3:30:00 PM to Train Station, Siena (Italy) arriving at 6/2/2026 10:20:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 50m
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Trenitalia7h 26m06:50 AMMilanCentral Station - Piazza Luigi di Savoia2:16 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 6:50:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 2:16:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 26m
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Trenitalia9h 0m08:14 AMMilanPorta Garibaldi Train Station5:14 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 6/2/2026 8:14:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 5:14:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 9h 0m
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Trenitalia6h 33m06:05 AMMilanCentral Station - Piazza Luigi di Savoia12:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 6:05:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 12:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 33m
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Trenitalia6h 30m012:10 PMMilanCentral Station - Piazza Luigi di Savoia6:40 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 12:10:00 PM to Train Station, Siena (Italy) arriving at 6/2/2026 6:40:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 30m
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Trenitalia5h 50m01:48 PMMilanCentral Station - Piazza Luigi di Savoia7:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 1:48:00 PM to Train Station, Siena (Italy) arriving at 6/2/2026 7:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 5h 50m
Cheapest Buses Tuesday
Cheapest Trains Tuesday
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/3/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/3/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/3/2026 10:40:00 AM to Piazza Antonio Gramsci, Siena (Italy) arriving at 6/3/2026 4:20:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 40m
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Itabus5h 15m012:35 PMMilanSan Donato Bus Station5:50 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/3/2026 12:35:00 PM to Train Station, Siena (Italy) arriving at 6/3/2026 5:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 15m
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Itabus5h 40m011:30 PMMilanSan Donato Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/3/2026 11:30:00 PM to Train Station, Siena (Italy) arriving at 6/4/2026 5:10:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 40m
Cheapest Buses Wednesday
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/4/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/4/2026 4:20:00 PM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 40m
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Itabus6h 30m010:40 PMMilanLampugnano Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/4/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 5:10:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 30m
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FlixBus9h 20m010:20 AMMilan Linate AirportMilan Linate Airport7:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 6/4/2026 10:20:00 AM to Train Station, Siena (Italy) arriving at 6/4/2026 7:40:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 9h 20m
Cheapest Buses Thursday
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 5h 40m
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Itabus5h 15m012:35 PMMilanSan Donato Bus Station5:50 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/5/2026 12:35:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 5:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 5h 15m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 12:30:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 6h 15m
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FlixBus7h 25m08:15 AMMilanLampugnano Bus Station3:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 3:40:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 7h 25m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 2:55:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 6h 35m
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Trenitalia8h 47m06:50 AMMilanCentral Station - Piazza Luigi di Savoia3:37 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 6:50:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 3:37:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 8h 47m
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Trenitalia6h 33m06:05 AMMilanCentral Station - Piazza Luigi di Savoia12:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 6:05:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 12:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 33m
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Trenitalia7h 42m07:55 AMMilanCentral Station - Piazza Luigi di Savoia3:37 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 7:55:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 3:37:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 7h 42m
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Trenitalia6h 30m012:10 PMMilanCentral Station - Piazza Luigi di Savoia6:40 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 12:10:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 6:40:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 30m
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Trenitalia5h 50m01:48 PMMilanCentral Station - Piazza Luigi di Savoia7:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 1:48:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 7:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 5h 50m
Cheapest Buses Friday
Cheapest Trains Friday
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FlixBus5h 45m05:35 AMMilanLampugnano Bus Station11:20 AMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 11:20:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 5h 45m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 12:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 15m
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FlixBus7h 25m08:15 AMMilanLampugnano Bus Station3:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 3:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 7h 25m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 4:20:00 PM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 40m
Cheapest Buses Saturday
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FlixBus5h 45m05:35 AMMilanLampugnano Bus Station11:20 AMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 11:20:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 5h 45m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 12:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 15m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 2:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 35m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 4:20:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 10:40:00 AM to Central Bus Station, Siena (Italy) arriving at 6/7/2026 4:20:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 5h 40m
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Trenitalia7h 26m06:50 AMMilanCentral Station - Piazza Luigi di Savoia2:16 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 6:50:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 2:16:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 26m
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Trenitalia6h 33m06:05 AMMilanCentral Station - Piazza Luigi di Savoia12:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 6:05:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 12:38:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 6h 33m
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Trenitalia9h 0m08:14 AMMilanPorta Garibaldi Train Station5:14 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 6/7/2026 8:14:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 5:14:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 9h 0m
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Trenitalia10h 0m08:40 AMMilanCentral Station - Piazza Luigi di Savoia6:40 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 8:40:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 6:40:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 0m
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Trenitalia5h 50m01:48 PMMilanCentral Station - Piazza Luigi di Savoia7:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 1:48:00 PM to Train Station, Siena (Italy) arriving at 6/7/2026 7:38:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 50m
Cheapest Buses Sunday
Cheapest Trains Sunday
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 12:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 15m
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FlixBus7h 25m08:15 AMMilanLampugnano Bus Station3:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 3:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 7h 25m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 2:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 35m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 5h 40m
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Itabus6h 30m010:40 PMMilanLampugnano Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 6/9/2026 5:10:00 AM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 30m
Cheapest Buses Monday
What are the fastest trips from Milan to Siena?
You can get to Siena from Milan in just 5h 15m with a Bus from Itabus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 4:20:00 PM. 50 Premium Economy ticket for $20 per person are available. Travel duration is 5h 40m
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Itabus5h 40m011:30 PMMilanSan Donato Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/2/2026 11:30:00 PM to Train Station, Siena (Italy) arriving at 6/3/2026 5:10:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 5h 40m
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Itabus6h 30m010:40 PMMilanLampugnano Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 6/3/2026 5:10:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 30m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 2:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 6h 35m
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FlixBus6h 50m03:30 PMMilanLampugnano Bus Station10:20 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/2/2026 3:30:00 PM to Train Station, Siena (Italy) arriving at 6/2/2026 10:20:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 50m
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Trenitalia5h 50m01:48 PMMilanCentral Station - Piazza Luigi di Savoia7:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 1:48:00 PM to Train Station, Siena (Italy) arriving at 6/2/2026 7:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 5h 50m
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Trenitalia6h 30m012:10 PMMilanCentral Station - Piazza Luigi di Savoia6:40 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 12:10:00 PM to Train Station, Siena (Italy) arriving at 6/2/2026 6:40:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 30m
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Trenitalia6h 33m06:05 AMMilanCentral Station - Piazza Luigi di Savoia12:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 6:05:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 12:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 33m
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Trenitalia7h 26m06:50 AMMilanCentral Station - Piazza Luigi di Savoia2:16 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/2/2026 6:50:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 2:16:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 26m
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Trenitalia9h 0m08:14 AMMilanPorta Garibaldi Train Station5:14 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 6/2/2026 8:14:00 AM to Train Station, Siena (Italy) arriving at 6/2/2026 5:14:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 9h 0m
Fastest Buses Tuesday
Fastest Trains Tuesday
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Itabus5h 15m012:35 PMMilanSan Donato Bus Station5:50 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/3/2026 12:35:00 PM to Train Station, Siena (Italy) arriving at 6/3/2026 5:50:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/3/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/3/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaPiazza Antonio Gramsci0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/3/2026 10:40:00 AM to Piazza Antonio Gramsci, Siena (Italy) arriving at 6/3/2026 4:20:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 40m
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Itabus5h 40m011:30 PMMilanSan Donato Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/3/2026 11:30:00 PM to Train Station, Siena (Italy) arriving at 6/4/2026 5:10:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 40m
Fastest Buses Wednesday
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/4/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/4/2026 4:20:00 PM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 40m
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Itabus6h 30m010:40 PMMilanLampugnano Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/4/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 5:10:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 6h 30m
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FlixBus9h 20m010:20 AMMilan Linate AirportMilan Linate Airport7:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Milan Linate Airport, Milan Linate Airport (Italy) at 6/4/2026 10:20:00 AM to Train Station, Siena (Italy) arriving at 6/4/2026 7:40:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 9h 20m
Fastest Buses Thursday
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Itabus5h 15m012:35 PMMilanSan Donato Bus Station5:50 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 6/5/2026 12:35:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 5:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 5h 15m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 5h 40m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 12:30:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 6h 15m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 2:55:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 6h 35m
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FlixBus7h 25m08:15 AMMilanLampugnano Bus Station3:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/5/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 3:40:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 7h 25m
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Trenitalia5h 50m01:48 PMMilanCentral Station - Piazza Luigi di Savoia7:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 1:48:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 7:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 5h 50m
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Trenitalia6h 30m012:10 PMMilanCentral Station - Piazza Luigi di Savoia6:40 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 12:10:00 PM to Train Station, Siena (Italy) arriving at 6/5/2026 6:40:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 30m
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Trenitalia6h 33m06:05 AMMilanCentral Station - Piazza Luigi di Savoia12:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 6:05:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 12:38:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 33m
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Trenitalia7h 42m07:55 AMMilanCentral Station - Piazza Luigi di Savoia3:37 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 7:55:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 3:37:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 7h 42m
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Trenitalia8h 47m06:50 AMMilanCentral Station - Piazza Luigi di Savoia3:37 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/5/2026 6:50:00 AM to Train Station, Siena (Italy) arriving at 6/5/2026 3:37:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 8h 47m
Fastest Buses Friday
Fastest Trains Friday
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 4:20:00 PM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 40m
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FlixBus5h 45m05:35 AMMilanLampugnano Bus Station11:20 AMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 11:20:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 5h 45m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 12:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 15m
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FlixBus7h 25m08:15 AMMilanLampugnano Bus Station3:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/6/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 6/6/2026 3:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 7h 25m
Fastest Buses Saturday
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 4:20:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 5h 40m
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaCentral Bus Station0EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 10:40:00 AM to Central Bus Station, Siena (Italy) arriving at 6/7/2026 4:20:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 5h 40m
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FlixBus5h 45m05:35 AMMilanLampugnano Bus Station11:20 AMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 5:35:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 11:20:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 5h 45m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 12:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 15m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/7/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 2:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 35m
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Trenitalia5h 50m01:48 PMMilanCentral Station - Piazza Luigi di Savoia7:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 1:48:00 PM to Train Station, Siena (Italy) arriving at 6/7/2026 7:38:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 50m
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Trenitalia6h 33m06:05 AMMilanCentral Station - Piazza Luigi di Savoia12:38 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 6:05:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 12:38:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 6h 33m
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Trenitalia7h 26m06:50 AMMilanCentral Station - Piazza Luigi di Savoia2:16 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 6:50:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 2:16:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 26m
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Trenitalia9h 0m08:14 AMMilanPorta Garibaldi Train Station5:14 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Porta Garibaldi Train Station, Milan (Italy) at 6/7/2026 8:14:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 5:14:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 9h 0m
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Trenitalia10h 0m08:40 AMMilanCentral Station - Piazza Luigi di Savoia6:40 PMSienaTrain Station0EconomyA Train from Trenitalia goes from Central Station - Piazza Luigi di Savoia, Milan (Italy) at 6/7/2026 8:40:00 AM to Train Station, Siena (Italy) arriving at 6/7/2026 6:40:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 0m
Fastest Buses Sunday
Fastest Trains Sunday
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Itabus5h 40m010:40 AMMilanLampugnano Bus Station4:20 PMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 10:40:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 5h 40m
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FlixBus6h 15m06:15 AMMilanLampugnano Bus Station12:30 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 6:15:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 12:30:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 15m
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Itabus6h 30m010:40 PMMilanLampugnano Bus Station5:10 AMSienaTrain Station0Premium EconomyA Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 10:40:00 PM to Train Station, Siena (Italy) arriving at 6/9/2026 5:10:00 AM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 30m
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FlixBus6h 35m08:20 AMMilanLampugnano Bus Station2:55 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 8:20:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 2:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 35m
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FlixBus7h 25m08:15 AMMilanLampugnano Bus Station3:40 PMSienaTrain Station0EconomyA Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 6/8/2026 8:15:00 AM to Train Station, Siena (Italy) arriving at 6/8/2026 3:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 7h 25m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Milan to Siena
What are the most popular stations in Milan and Siena?
In Milan, you will usually depart from Central Station - Piazza Luigi di Savoia, Lampugnano Bus Station or Cadorna Train Station, while in Siena you will be arriving at Train Station, Bus Stop or Central Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Siena from Milan? With 7 connections between 3 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Milan and Siena, you can pay as low as $9 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Itabus: you will get to Siena in just 5h 15m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Milan and Siena are Itabus, FlixBus and Trenitalia, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Milan and Siena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Corsico or to Castagno, and look at flights from Bergamo Airport, and landing at . Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Milan to Siena?
The most popular companies between Milan and Siena, are Itabus, FlixBus and Trenitalia. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Train companies: Trenitalia
All you need to know when you travel from Milan to Siena
Check all information on comfort and services on all modes of transports from Milan to Siena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Milan to Siena
How can I reach Siena from Milan?
Every day, there are on average 7 connections between Train and Bus, with which you can get to Siena from Milan.
How far is Siena from Milan?
The distance between Milan and Siena is 182.3 miles.
What is the most ecofriendly mode of transport between Milan and Siena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Milan to Siena?
You can get to Siena with just $9 by taking a Bus from FlixBus.
What is the fastest way to get from Milan to Siena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Siena in just 5h 15m with a Bus from Itabus.
More routes to Milan and to Siena
Looking for more options? Here you can see the most popular routes to Milan and to Siena. Simply click on a connection, and you’ll find all the details about the route!
