What is the best way to travel from Siena to Milan?
Looking for a trip? Compare all the available Carpool, Trains and Buses for the journey to Milan from Siena. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Milan from Siena?
You can get to Milan with just $8 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus4h 55m01:55 PMSienaTrain Station6:50 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/7/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/7/2026 6:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 55m
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Itabus4h 55m01:55 PMSienaCentral Bus Station6:50 PMMilanSan Donato Bus Station0EconomyA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 11/7/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/7/2026 6:50:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 55m
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Itabus5h 10m05:55 PMSienaCentral Bus Station11:05 PMMilanSan Donato Bus Station0EconomyA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 11/7/2026 5:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/7/2026 11:05:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 10m
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FlixBus5h 40m012:15 PMSienaTrain Station5:55 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 11/7/2026 12:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/7/2026 5:55:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 40m
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Trenitalia8h 9m06:36 AMSienaTrain Station2:45 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 6:36:00 AM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/7/2026 2:45:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 8h 9m
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Trenitalia8h 12m03:18 PMSienaTrain Station11:30 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 3:18:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/7/2026 11:30:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 12m
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Trenitalia9h 57m011:18 AMSienaTrain Station9:15 PMMilanPorta Garibaldi Train Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 11:18:00 AM to Porta Garibaldi Train Station, Milan (Italy) arriving at 11/7/2026 9:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 9h 57m
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Trenitalia7h 4m06:36 AMSienaTrain Station1:40 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 6:36:00 AM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/7/2026 1:40:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 7h 4m
Cheapest Buses Saturday
Cheapest Trains Saturday
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Itabus4h 55m01:55 PMSienaTrain Station6:50 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/8/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/8/2026 6:50:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 55m
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Itabus5h 10m05:55 PMSienaTrain Station11:05 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/8/2026 5:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/8/2026 11:05:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 10m
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Itabus5h 50m01:05 AMSienaTrain Station6:55 AMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/8/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/8/2026 6:55:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 5h 50m
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/8/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/8/2026 9:40:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 6h 49m
Cheapest Buses Sunday
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FlixBus5h 50m06:10 AMSienaTrain Station12:00 PMMilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 11/9/2026 6:10:00 AM to San Donato Bus Station, Milan (Italy) arriving at 11/9/2026 12:00:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 5h 50m
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FlixBus6h 50m06:10 AMSienaTrain Station1:00 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 11/9/2026 6:10:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/9/2026 1:00:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 50m
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FlixBus7h 20m02:25 PMSienaTrain Station9:45 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 11/9/2026 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/9/2026 9:45:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 7h 20m
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/9/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/9/2026 4:40:00 PM. 50 Premium Economy ticket for $14 per person are available. Travel duration is 5h 45m
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Trenitalia6h 42m03:18 PMSienaTrain Station10:00 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 3:18:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 10:00:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 6h 42m
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Trenitalia6h 41m04:41 PMSienaTrain Station11:22 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 4:41:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 11:22:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 6h 41m
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Trenitalia4h 8m06:42 PMSienaTrain Station10:50 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 6:42:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 10:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 4h 8m
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Trenitalia4h 32m07:18 PMSienaTrain Station11:50 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 7:18:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 11:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 4h 32m
Cheapest Buses Monday
Cheapest Trains Monday
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/10/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/10/2026 9:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 49m
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/10/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/10/2026 4:40:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 5h 45m
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Itabus5h 50m01:05 AMSienaTrain Station6:55 AMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/10/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/10/2026 6:55:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 50m
Cheapest Buses Tuesday
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/11/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/11/2026 4:40:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 5h 45m
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/11/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/11/2026 9:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 49m
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Itabus5h 50m01:05 AMSienaTrain Station6:55 AMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/11/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/11/2026 6:55:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 50m
Cheapest Buses Wednesday
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/12/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/12/2026 4:40:00 PM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 5h 45m
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/12/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/12/2026 9:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 49m
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Itabus4h 55m01:55 PMSienaTrain Station6:50 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/12/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/12/2026 6:50:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 4h 55m
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Itabus5h 10m05:55 PMSienaTrain Station11:05 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/12/2026 5:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/12/2026 11:05:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 5h 10m
Cheapest Buses Thursday
What are the fastest trips from Siena to Milan?
You can get to Milan from Siena in just 4h 8m with a Train from Trenitalia. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Itabus4h 55m01:55 PMSienaTrain Station6:50 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/7/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/7/2026 6:50:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 55m
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Itabus4h 55m01:55 PMSienaCentral Bus Station6:50 PMMilanSan Donato Bus Station0EconomyA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 11/7/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/7/2026 6:50:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 55m
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Itabus5h 10m05:55 PMSienaCentral Bus Station11:05 PMMilanSan Donato Bus Station0EconomyA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 11/7/2026 5:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/7/2026 11:05:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 10m
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FlixBus5h 40m012:15 PMSienaTrain Station5:55 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 11/7/2026 12:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/7/2026 5:55:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 40m
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Trenitalia5h 50m06:25 AMSienaTrain Station12:15 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 6:25:00 AM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/7/2026 12:15:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 5h 50m
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Trenitalia7h 4m06:36 AMSienaTrain Station1:40 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 6:36:00 AM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/7/2026 1:40:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 7h 4m
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Trenitalia8h 9m06:36 AMSienaTrain Station2:45 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 6:36:00 AM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/7/2026 2:45:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 8h 9m
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Trenitalia8h 12m03:18 PMSienaTrain Station11:30 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/7/2026 3:18:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/7/2026 11:30:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 12m
Fastest Buses Saturday
Fastest Trains Saturday
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Itabus4h 55m01:55 PMSienaTrain Station6:50 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/8/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/8/2026 6:50:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 4h 55m
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Itabus5h 10m05:55 PMSienaTrain Station11:05 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/8/2026 5:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/8/2026 11:05:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 10m
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Itabus5h 50m01:05 AMSienaTrain Station6:55 AMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/8/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/8/2026 6:55:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 5h 50m
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/8/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/8/2026 9:40:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 6h 49m
Fastest Buses Sunday
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Trenitalia4h 8m06:42 PMSienaTrain Station10:50 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 6:42:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 10:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 4h 8m
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Trenitalia4h 9m07:41 PMSienaTrain Station11:50 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 7:41:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 11:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 4h 9m
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Trenitalia4h 32m07:18 PMSienaTrain Station11:50 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 7:18:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 11:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 4h 32m
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Trenitalia6h 41m04:41 PMSienaTrain Station11:22 PMMilanCentral Station - Piazza Luigi di Savoia0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 11/9/2026 4:41:00 PM to Central Station - Piazza Luigi di Savoia, Milan (Italy) arriving at 11/9/2026 11:22:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 6h 41m
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/9/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/9/2026 4:40:00 PM. 50 Premium Economy ticket for $14 per person are available. Travel duration is 5h 45m
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Itabus5h 45m010:55 AMSienaCentral Bus Station4:40 PMMilanLampugnano Bus Station0EconomyA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 11/9/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/9/2026 4:40:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 5h 45m
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FlixBus5h 50m06:10 AMSienaTrain Station12:00 PMMilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 11/9/2026 6:10:00 AM to San Donato Bus Station, Milan (Italy) arriving at 11/9/2026 12:00:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 5h 50m
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FlixBus6h 50m06:10 AMSienaTrain Station1:00 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 11/9/2026 6:10:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/9/2026 1:00:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 50m
Fastest Trains Monday
Fastest Buses Monday
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/10/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/10/2026 4:40:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 5h 45m
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Itabus5h 50m01:05 AMSienaTrain Station6:55 AMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/10/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/10/2026 6:55:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 50m
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/10/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/10/2026 9:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 49m
Fastest Buses Tuesday
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/11/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/11/2026 4:40:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 5h 45m
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Itabus5h 50m01:05 AMSienaTrain Station6:55 AMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/11/2026 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/11/2026 6:55:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 50m
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/11/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/11/2026 9:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 49m
Fastest Buses Wednesday
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Itabus4h 55m01:55 PMSienaTrain Station6:50 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/12/2026 1:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/12/2026 6:50:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 4h 55m
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Itabus5h 10m05:55 PMSienaTrain Station11:05 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/12/2026 5:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 11/12/2026 11:05:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 5h 10m
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Itabus5h 45m010:55 AMSienaTrain Station4:40 PMMilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 11/12/2026 10:55:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 11/12/2026 4:40:00 PM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 5h 45m
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FlixBus6h 49m02:51 PMSienaBus Stop9:40 PMMilanLampugnano Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 11/12/2026 2:51:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 11/12/2026 9:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 6h 49m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Siena to Milan
What are the most popular stations in Siena and Milan?
In Siena, you will usually depart from Central Bus Station, Train Station or Bus Stop, while in Milan you will be arriving at Lampugnano Bus Station, Cadorna Train Station or Central Station - Piazza Luigi di Savoia, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Milan from Siena? With 6 connections between 3 Carpool, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Siena and Milan, you can pay as low as $8 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Trenitalia: you will get to Milan in just 4h 8m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Siena and Milan are Itabus, Trenitalia and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Siena and Milan is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Castagno or to Corsico, and look at flights from , and landing at Bergamo Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Siena to Milan?
The most popular companies between Siena and Milan, are Itabus, Trenitalia and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Train companies: Trenitalia
All you need to know when you travel from Siena to Milan
Check all information on comfort and services on all modes of transports from Siena to Milan. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Siena to Milan
How can I reach Milan from Siena?
Every day, there are on average 6 connections between Carpool, Train and Bus, with which you can get to Milan from Siena.
How far is Milan from Siena?
The distance between Siena and Milan is 182.3 miles.
What is the most ecofriendly mode of transport between Siena and Milan?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Siena to Milan?
You can get to Milan with just $8 by taking a Bus from FlixBus.
What is the fastest way to get from Siena to Milan?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Milan in just 4h 8m with a Train from Trenitalia.
More routes to Siena and to Milan
Looking for more options? Here you can see the most popular routes to Siena and to Milan. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Siena
- Arezzo to Siena
- Assisi to Siena
- Avellino to Siena
- Benevento to Siena
- Bologna to Siena
- Caserta to Siena
- Cassino to Siena
- Cosenza to Siena
- Ferrara to Siena
- Florence to Siena
- Genoa to Siena
- Lecce to Siena
- Lucca to Siena
- Matera to Siena
- Milan to Siena
- Naples to Siena
- Padua to Siena
- Perugia to Siena
- Pescara to Siena
- Pisa to Siena
- Rome to Siena
- Salerno to Siena
- Trips to Milan
- Barcelona to Milan
- Bari to Milan
- Bergamo Airport to Milan
- Bergamo to Milan
- Brescia to Milan
- Breuil-Cervinia to Milan
- Bucharest to Milan
- Chatillon to Milan
- Finale Ligure to Milan
- Florence to Milan
- Forlì to Milan
- Lugano to Milan
- Marseille to Milan
- Milan Linate Airport to Milan
- Modena to Milan
- Paris to Milan
- Perugia to Milan
- Reggio Calabria to Milan
- Rome to Milan
- Trieste to Milan
- Turin to Milan
- Venice to Milan
- Verrès to Milan
- Vibo Valentia to Milan
