What is the best way to travel from Rome to Prague?
Looking for a trip? Compare all the available Flights and Buses for the journey to Prague from Rome. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Rome?
You can get to Prague with just $23 by taking a Flight from Skyscanner, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Skyscanner1h 50m06:05 AMRome Ciampino AirportRome Ciampino Airport7:55 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/2/2026 6:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 7:55:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m06:05 AMRome Ciampino AirportRome Ciampino Airport7:55 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/2/2026 6:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 7:55:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/2/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 8:40:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 55m
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Wizz Air20h 25m06:35 PMRome Fiumicino AirportRome Fiumicino Airport3:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/2/2026 6:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 3:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 20h 25m
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Condor5h 0m011:00 AMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/2/2026 11:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 4:00:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 5h 0m
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FlixBus26h 55m09:00 PMRomeTiburtina Bus Station11:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/3/2026 11:55:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 26h 55m
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FlixBus20h 30m09:00 PMRomeTiburtina Bus Station5:30 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/3/2026 5:30:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m09:00 PMRomeTiburtina Bus Station5:45 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/3/2026 5:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 20h 45m
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FlixBus28h 30m09:30 AMRomeTiburtina Bus Station2:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/3/2026 2:00:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 28h 30m
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FlixBus23h 25m09:30 AMRomeTiburtina Bus Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/3/2026 8:55:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 23h 25m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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Skyscanner1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/3/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 7:50:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/3/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 7:50:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/3/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 8:40:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 1h 55m
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Buzz7h 45m010:40 AMRome Ciampino AirportRome Ciampino Airport6:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/3/2026 10:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 6:25:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 7h 45m
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Condor4h 50m011:10 AMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/3/2026 11:10:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 4:00:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 4h 50m
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FlixBus20h 35m010:55 PMRomeTiburtina Bus Station7:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 10:55:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/4/2026 7:30:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 35m
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FlixBus20h 25m010:55 PMRomeTiburtina Bus Station7:20 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 10:55:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/4/2026 7:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 25m
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FlixBus26h 55m09:00 PMRomeTiburtina Bus Station11:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/4/2026 11:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 26h 55m
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FlixBus24h 0m010:55 PMRomeTiburtina Bus Station10:55 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 10:55:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/4/2026 10:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 24h 0m
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FlixBus22h 15m07:30 AMRomeTiburtina Bus Station5:45 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 7:30:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/4/2026 5:45:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 22h 15m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
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Skyscanner1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/4/2026 7:50:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/4/2026 7:50:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/4/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/4/2026 8:40:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 55m
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Buzz14h 25m04:35 PMRome Ciampino AirportRome Ciampino Airport7:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 4:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:00:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 14h 25m
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Wizz Air9h 50m09:10 PMRome Fiumicino AirportRome Fiumicino Airport7:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/4/2026 9:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:00:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 9h 50m
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FlixBus22h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 10:45:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/5/2026 9:25:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 40m
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FlixBus20h 50m05:05 PMRomeTiburtina Bus Station1:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/4/2026 5:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/5/2026 1:55:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 50m
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FlixBus20h 40m05:05 PMRomeTiburtina Bus Station1:45 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/4/2026 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/5/2026 1:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 40m
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FlixBus27h 40m011:35 PMRomeAnagnina Bus Station3:15 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/4/2026 11:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/6/2026 3:15:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 40m
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FlixBus25h 25m012:20 PMRomeTiburtina Bus Station1:45 PMPragueČerný Most0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/4/2026 12:20:00 PM to Černý Most, Prague (Czech Republic) arriving at 6/5/2026 1:45:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 25h 25m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Skyscanner1h 50m05:30 PMRome Ciampino AirportRome Ciampino Airport7:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/5/2026 5:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/5/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 8:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 1h 55m
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Wizz Air1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/5/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 8:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 1h 55m
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Ryanair1h 50m05:30 PMRome Ciampino AirportRome Ciampino Airport7:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/5/2026 5:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:20:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 1h 50m
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Smartwings2h 0m02:00 PMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/5/2026 2:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 4:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 2h 0m
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FlixBus24h 25m01:05 PMRomeAnagnina Bus Station1:30 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/5/2026 1:05:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/6/2026 1:30:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 24h 25m
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FlixBus22h 15m07:30 AMRomeTiburtina Bus Station5:45 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 7:30:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/6/2026 5:45:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 22h 15m
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FlixBus20h 50m05:05 PMRomeTiburtina Bus Station1:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 5:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/6/2026 1:55:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 50m
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FlixBus22h 45m011:50 AMRomeTiburtina Bus Station10:35 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 11:50:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/6/2026 10:35:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 22h 45m
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FlixBus20h 40m05:05 PMRomeTiburtina Bus Station1:45 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/6/2026 1:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 40m
Cheapest Flights Friday
Cheapest Buses Friday
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Wizz Air1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/6/2026 8:40:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 1h 55m
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ITA Airways13h 30m07:00 PMRome Fiumicino AirportRome Fiumicino Airport8:30 AMPrague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 7:00:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/7/2026 8:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 13h 30m
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Vueling Airlines27h 10m010:30 AMRome Fiumicino AirportRome Fiumicino Airport1:40 PMPrague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 10:30:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/7/2026 1:40:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 27h 10m
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Smartwings2h 0m02:00 PMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport0EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 2:00:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/6/2026 4:00:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 2h 0m
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Transavia France9h 20m012:25 PMRome Fiumicino AirportRome Fiumicino Airport9:45 PMPrague AirportPrague Airport0EconomyA Flight from Transavia France goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 12:25:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/6/2026 9:45:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 9h 20m
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FlixBus24h 35m012:45 PMRomeAnagnina Bus Station1:20 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 12:45:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/7/2026 1:20:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 35m
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FlixBus21h 30m01:05 PMRomeAnagnina Bus Station10:35 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 1:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/7/2026 10:35:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 30m
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FlixBus25h 0m012:45 PMRomeAnagnina Bus Station1:45 PMPragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 12:45:00 PM to Černý Most, Prague (Czech Republic) arriving at 6/7/2026 1:45:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 25h 0m
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FlixBus20h 20m01:05 PMRomeAnagnina Bus Station9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 1:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/7/2026 9:25:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 20h 20m
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FlixBus21h 5m012:20 PMRomeTiburtina Bus Station9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/6/2026 12:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/7/2026 9:25:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 21h 5m
Cheapest Flights Saturday
Cheapest Buses Saturday
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Wizz Air21h 0m06:00 PMRome Fiumicino AirportRome Fiumicino Airport3:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/7/2026 6:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 3:00:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 21h 0m
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Ryanair15h 30m06:35 AMRome Ciampino AirportRome Ciampino Airport10:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 6:35:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 10:05:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 15h 30m
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Skyscanner7h 40m01:00 PMRome Ciampino AirportRome Ciampino Airport8:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 8:40:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 7h 40m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/7/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 8:40:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 1h 55m
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Buzz9h 50m07:40 AMRome Ciampino AirportRome Ciampino Airport5:30 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 7:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 5:30:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 9h 50m
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FlixBus27h 40m011:35 PMRomeAnagnina Bus Station3:15 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/7/2026 11:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/9/2026 3:15:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 27h 40m
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FlixBus26h 45m010:45 AMRome Ciampino AirportRome Ciampino Airport1:30 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 10:45:00 AM to Roztyly, Prague (Czech Republic) arriving at 6/8/2026 1:30:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 26h 45m
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FlixBus24h 25m01:05 PMRomeAnagnina Bus Station1:30 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/7/2026 1:05:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/8/2026 1:30:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 24h 25m
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FlixBus25h 0m012:20 PMRomeTiburtina Bus Station1:20 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/7/2026 12:20:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/8/2026 1:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 25h 0m
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FlixBus25h 0m012:45 PMRomeAnagnina Bus Station1:45 PMPragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/7/2026 12:45:00 PM to Černý Most, Prague (Czech Republic) arriving at 6/8/2026 1:45:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 25h 0m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Wizz Air1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/8/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 8:40:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/8/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 8:40:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 55m
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Skyscanner1h 50m011:15 AMRome Ciampino AirportRome Ciampino Airport1:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/8/2026 11:15:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 1:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m011:15 AMRome Ciampino AirportRome Ciampino Airport1:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/8/2026 11:15:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 1:05:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 1h 50m
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Vueling Airlines11h 55m09:55 PMRome Fiumicino AirportRome Fiumicino Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/8/2026 9:55:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/9/2026 9:50:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 11h 55m
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FlixBus22h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/8/2026 10:45:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/9/2026 9:25:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 22h 40m
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FlixBus27h 40m011:35 PMRomeAnagnina Bus Station3:15 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/8/2026 11:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/10/2026 3:15:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 27h 40m
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FlixBus22h 45m09:20 PMRomeTiburtina Bus Station8:05 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/8/2026 9:20:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/9/2026 8:05:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 22h 45m
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FlixBus23h 20m09:00 PMRomeTiburtina Bus Station8:20 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/8/2026 9:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/9/2026 8:20:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 20m
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FlixBus22h 55m09:20 PMRomeTiburtina Bus Station8:15 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/8/2026 9:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/9/2026 8:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 22h 55m
Cheapest Flights Monday
Cheapest Buses Monday
What are the fastest trips from Rome to Prague?
You can get to Prague from Rome in just 1h 50m with a Flight from Skyscanner. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Skyscanner1h 50m06:05 AMRome Ciampino AirportRome Ciampino Airport7:55 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/2/2026 6:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 7:55:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m06:05 AMRome Ciampino AirportRome Ciampino Airport7:55 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/2/2026 6:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 7:55:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/2/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 8:40:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 55m
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Condor5h 0m011:00 AMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/2/2026 11:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/2/2026 4:00:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 5h 0m
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Wizz Air20h 25m06:35 PMRome Fiumicino AirportRome Fiumicino Airport3:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/2/2026 6:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 3:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 20h 25m
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FlixBus20h 30m09:00 PMRomeTiburtina Bus Station5:30 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/3/2026 5:30:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m09:00 PMRomeTiburtina Bus Station5:45 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/3/2026 5:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 20h 45m
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FlixBus23h 25m09:30 AMRomeTiburtina Bus Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:30:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/3/2026 8:55:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 23h 25m
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FlixBus26h 55m09:00 PMRomeTiburtina Bus Station11:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/3/2026 11:55:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 26h 55m
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FlixBus28h 30m09:30 AMRomeTiburtina Bus Station2:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/2/2026 9:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/3/2026 2:00:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 28h 30m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Skyscanner1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/3/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 7:50:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/3/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 7:50:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/3/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 8:40:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 1h 55m
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Condor4h 50m011:10 AMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/3/2026 11:10:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 4:00:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 4h 50m
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Buzz7h 45m010:40 AMRome Ciampino AirportRome Ciampino Airport6:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/3/2026 10:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/3/2026 6:25:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 7h 45m
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FlixBus20h 25m010:55 PMRomeTiburtina Bus Station7:20 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 10:55:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/4/2026 7:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 25m
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FlixBus20h 35m010:55 PMRomeTiburtina Bus Station7:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 10:55:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/4/2026 7:30:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 35m
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FlixBus22h 15m07:30 AMRomeTiburtina Bus Station5:45 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 7:30:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/4/2026 5:45:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 22h 15m
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FlixBus24h 0m010:55 PMRomeTiburtina Bus Station10:55 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 10:55:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/4/2026 10:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 24h 0m
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FlixBus26h 55m09:00 PMRomeTiburtina Bus Station11:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/3/2026 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/4/2026 11:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 26h 55m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Skyscanner1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/4/2026 7:50:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m06:00 AMRome Ciampino AirportRome Ciampino Airport7:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 6:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/4/2026 7:50:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/4/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/4/2026 8:40:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 55m
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Wizz Air9h 50m09:10 PMRome Fiumicino AirportRome Fiumicino Airport7:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/4/2026 9:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:00:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 9h 50m
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Buzz14h 25m04:35 PMRome Ciampino AirportRome Ciampino Airport7:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 4:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:00:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 14h 25m
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FlixBus20h 40m05:05 PMRomeTiburtina Bus Station1:45 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/4/2026 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/5/2026 1:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 40m
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FlixBus20h 50m05:05 PMRomeTiburtina Bus Station1:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/4/2026 5:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/5/2026 1:55:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 50m
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FlixBus22h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/4/2026 10:45:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/5/2026 9:25:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 40m
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FlixBus25h 25m012:20 PMRomeTiburtina Bus Station1:45 PMPragueČerný Most0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/4/2026 12:20:00 PM to Černý Most, Prague (Czech Republic) arriving at 6/5/2026 1:45:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 25h 25m
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FlixBus27h 40m011:35 PMRomeAnagnina Bus Station3:15 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/4/2026 11:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/6/2026 3:15:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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Skyscanner1h 50m05:30 PMRome Ciampino AirportRome Ciampino Airport7:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/5/2026 5:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m05:30 PMRome Ciampino AirportRome Ciampino Airport7:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/5/2026 5:30:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 7:20:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/5/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 8:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 1h 55m
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Wizz Air1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/5/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 8:40:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m02:00 PMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/5/2026 2:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/5/2026 4:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 2h 0m
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FlixBus20h 40m05:05 PMRomeTiburtina Bus Station1:45 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/6/2026 1:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 40m
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FlixBus20h 50m05:05 PMRomeTiburtina Bus Station1:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 5:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/6/2026 1:55:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 50m
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FlixBus22h 15m07:30 AMRomeTiburtina Bus Station5:45 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 7:30:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/6/2026 5:45:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 22h 15m
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FlixBus22h 45m011:50 AMRomeTiburtina Bus Station10:35 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/5/2026 11:50:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/6/2026 10:35:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 22h 45m
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FlixBus24h 25m01:05 PMRomeAnagnina Bus Station1:30 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/5/2026 1:05:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/6/2026 1:30:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 24h 25m
Fastest Flights Friday
Fastest Buses Friday
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Wizz Air1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/6/2026 8:40:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 1h 55m
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Smartwings2h 0m02:00 PMRome Fiumicino AirportRome Fiumicino Airport4:00 PMPrague AirportPrague Airport0EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 2:00:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/6/2026 4:00:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 2h 0m
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Transavia France9h 20m012:25 PMRome Fiumicino AirportRome Fiumicino Airport9:45 PMPrague AirportPrague Airport0EconomyA Flight from Transavia France goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 12:25:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/6/2026 9:45:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 9h 20m
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ITA Airways13h 30m07:00 PMRome Fiumicino AirportRome Fiumicino Airport8:30 AMPrague AirportPrague Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 7:00:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/7/2026 8:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 13h 30m
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Vueling Airlines27h 10m010:30 AMRome Fiumicino AirportRome Fiumicino Airport1:40 PMPrague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/6/2026 10:30:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 6/7/2026 1:40:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 27h 10m
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FlixBus20h 20m01:05 PMRomeAnagnina Bus Station9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 1:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/7/2026 9:25:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 20h 20m
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FlixBus21h 5m012:20 PMRomeTiburtina Bus Station9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/6/2026 12:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/7/2026 9:25:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 21h 5m
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FlixBus21h 30m01:05 PMRomeAnagnina Bus Station10:35 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 1:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/7/2026 10:35:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 30m
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FlixBus24h 35m012:45 PMRomeAnagnina Bus Station1:20 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 12:45:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/7/2026 1:20:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 35m
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FlixBus25h 0m012:45 PMRomeAnagnina Bus Station1:45 PMPragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/6/2026 12:45:00 PM to Černý Most, Prague (Czech Republic) arriving at 6/7/2026 1:45:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 25h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/7/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 8:40:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 1h 55m
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Skyscanner7h 40m01:00 PMRome Ciampino AirportRome Ciampino Airport8:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 8:40:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 7h 40m
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Buzz9h 50m07:40 AMRome Ciampino AirportRome Ciampino Airport5:30 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Buzz goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 7:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 5:30:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 9h 50m
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Ryanair15h 30m06:35 AMRome Ciampino AirportRome Ciampino Airport10:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 6:35:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/7/2026 10:05:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 15h 30m
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Wizz Air21h 0m06:00 PMRome Fiumicino AirportRome Fiumicino Airport3:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/7/2026 6:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 3:00:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 21h 0m
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FlixBus24h 25m01:05 PMRomeAnagnina Bus Station1:30 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/7/2026 1:05:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/8/2026 1:30:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 24h 25m
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FlixBus25h 0m012:20 PMRomeTiburtina Bus Station1:20 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/7/2026 12:20:00 PM to Roztyly, Prague (Czech Republic) arriving at 6/8/2026 1:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 25h 0m
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FlixBus25h 0m012:45 PMRomeAnagnina Bus Station1:45 PMPragueČerný Most0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/7/2026 12:45:00 PM to Černý Most, Prague (Czech Republic) arriving at 6/8/2026 1:45:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 25h 0m
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FlixBus26h 45m010:45 AMRome Ciampino AirportRome Ciampino Airport1:30 PMPragueRoztyly0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/7/2026 10:45:00 AM to Roztyly, Prague (Czech Republic) arriving at 6/8/2026 1:30:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 26h 45m
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FlixBus27h 40m011:35 PMRomeAnagnina Bus Station3:15 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/7/2026 11:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/9/2026 3:15:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 27h 40m
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Skyscanner1h 50m011:15 AMRome Ciampino AirportRome Ciampino Airport1:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/8/2026 11:15:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 1:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m011:15 AMRome Ciampino AirportRome Ciampino Airport1:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/8/2026 11:15:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 1:05:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 1h 50m
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Wizz Air1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/8/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 8:40:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m06:45 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/8/2026 6:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/8/2026 8:40:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 55m
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Vueling Airlines11h 55m09:55 PMRome Fiumicino AirportRome Fiumicino Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 6/8/2026 9:55:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/9/2026 9:50:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 11h 55m
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FlixBus22h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport9:25 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 6/8/2026 10:45:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/9/2026 9:25:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 22h 40m
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FlixBus22h 45m09:20 PMRomeTiburtina Bus Station8:05 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/8/2026 9:20:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/9/2026 8:05:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 22h 45m
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FlixBus22h 55m09:20 PMRomeTiburtina Bus Station8:15 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/8/2026 9:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/9/2026 8:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 22h 55m
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FlixBus23h 20m09:00 PMRomeTiburtina Bus Station8:20 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 6/8/2026 9:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/9/2026 8:20:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 20m
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FlixBus27h 40m011:35 PMRomeAnagnina Bus Station3:15 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 6/8/2026 11:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/10/2026 3:15:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 27h 40m
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Here you will find all operators and timetables for a
Bus from Rome to Prague
What are the most popular stations in Rome and Prague?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Prague you will be arriving at Wilsonova Bus Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Rome? With 10 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Prague, you can pay as low as $23 with a Flight from Skyscanner.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Prague in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Prague are FlixBus, Skyscanner and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Horoměřice, and look at flights from Rome Ciampino Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Prague?
The most popular companies between Rome and Prague, are FlixBus, Skyscanner and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Skyscanner, Ryanair, LC Perú and 7 more.
All you need to know when you travel from Rome to Prague
Check all information on comfort and services on all modes of transports from Rome to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Prague
How can I reach Prague from Rome?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to Prague from Rome.
How far is Prague from Rome?
The distance between Rome and Prague is 572.5 miles.
What is the most ecofriendly mode of transport between Rome and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Rome to Prague?
You can get to Prague with just $23 by taking a Flight from Skyscanner.
What is the fastest way to get from Rome to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 50m with a Flight from Skyscanner.
More routes to Rome and to Prague
Looking for more options? Here you can see the most popular routes to Rome and to Prague. Simply click on a connection, and you’ll find all the details about the route!
