What is the best way to travel from Pisa to Rome?
Looking for a trip? Compare all the available Carpool, Trains and Buses for the journey to Rome from Pisa. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Pisa?
You can get to Rome with just $14 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/7/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m01:25 PMPisaParking Aurelia6:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/7/2026 1:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 6:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/7/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
MarinoBus6h 0m08:20 AMPisaPietrasantina Bus Station2:20 PMRomeTiburtina Bus Station0EconomyA Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 2/7/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 2:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 0m
-
Trenitalia3h 22m02:21 AMPisaCentral Station5:43 AMRomeOstiense Train Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 2:21:00 AM to Ostiense Train Station, Rome (Italy) arriving at 2/7/2026 5:43:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 3h 22m
-
Trenitalia2h 56m07:07 AMPisaCentral Station10:03 AMRomeTermini Central Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 7:07:00 AM to Termini Central Station, Rome (Italy) arriving at 2/7/2026 10:03:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 56m
-
Trenitalia2h 56m09:07 AMPisaCentral Station12:03 PMRomeTermini Central Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 9:07:00 AM to Termini Central Station, Rome (Italy) arriving at 2/7/2026 12:03:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 56m
-
Trenitalia2h 56m02:07 PMPisaCentral Station5:03 PMRomeTermini Central Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 2:07:00 PM to Termini Central Station, Rome (Italy) arriving at 2/7/2026 5:03:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 56m
Cheapest Buses Saturday
Cheapest Trains Saturday
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 10:35:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 5h 10m
-
FlixBus5h 30m012:25 AMPisaParking Aurelia5:55 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 5:55:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 30m
-
FlixBus6h 5m07:15 AMPisaParking Aurelia1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 1:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 5m
Cheapest Buses Sunday
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/9/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus6h 5m07:15 AMPisaParking Aurelia1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/9/2026 1:20:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 5m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/9/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus4h 35m010:00 PMPisaParking Aurelia2:35 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 10:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 2:35:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 35m
Cheapest Buses Monday
-
FlixBus6h 5m07:15 AMPisaParking Aurelia1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 1:20:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 6h 5m
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m01:25 PMPisaParking Aurelia6:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 1:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 6:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus5h 30m012:25 AMPisaParking Aurelia5:55 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 5:55:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 5h 30m
Cheapest Buses Tuesday
-
FlixBus6h 5m07:15 AMPisaParking Aurelia1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/11/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/11/2026 1:20:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 5m
-
FlixBus6h 15m05:20 PMPisaParking Aurelia11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/11/2026 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/11/2026 11:35:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 6h 15m
Cheapest Buses Wednesday
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/12/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/12/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus4h 35m010:00 PMPisaParking Aurelia2:35 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 10:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 2:35:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 35m
-
FlixBus6h 5m012:00 PMPisaParking Aurelia6:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 12:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 2/12/2026 6:05:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 6h 5m
Cheapest Buses Thursday
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus6h 35m07:15 AMPisaParking Aurelia1:50 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 1:50:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 6h 35m
-
FlixBus5h 30m012:25 AMPisaParking Aurelia5:55 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 5:55:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 30m
Cheapest Buses Friday
What are the fastest trips from Pisa to Rome?
You can get to Rome from Pisa in just 2h 56m with a Train from Trenitalia. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
Trenitalia2h 56m07:07 AMPisaCentral Station10:03 AMRomeTermini Central Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 7:07:00 AM to Termini Central Station, Rome (Italy) arriving at 2/7/2026 10:03:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 56m
-
Trenitalia2h 56m09:07 AMPisaCentral Station12:03 PMRomeTermini Central Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 9:07:00 AM to Termini Central Station, Rome (Italy) arriving at 2/7/2026 12:03:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 56m
-
Trenitalia2h 56m02:07 PMPisaCentral Station5:03 PMRomeTermini Central Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 2:07:00 PM to Termini Central Station, Rome (Italy) arriving at 2/7/2026 5:03:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 56m
-
Trenitalia2h 56m05:07 PMPisaCentral Station8:03 PMRomeTermini Central Station0EconomyA Train from Trenitalia goes from Central Station, Pisa (Italy) at 2/7/2026 5:07:00 PM to Termini Central Station, Rome (Italy) arriving at 2/7/2026 8:03:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 56m
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/7/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m01:25 PMPisaParking Aurelia6:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/7/2026 1:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 6:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/7/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
MarinoBus6h 0m08:20 AMPisaPietrasantina Bus Station2:20 PMRomeTiburtina Bus Station0EconomyA Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 2/7/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/7/2026 2:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 0m
Fastest Trains Saturday
Fastest Buses Saturday
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 10:35:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 5h 10m
-
FlixBus5h 25m012:00 PMPisaParking Aurelia5:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 12:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 5:25:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 25m
-
FlixBus5h 30m012:25 AMPisaParking Aurelia5:55 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/8/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/8/2026 5:55:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 30m
Fastest Buses Sunday
-
FlixBus4h 35m010:00 PMPisaParking Aurelia2:35 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 10:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 2:35:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 35m
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/9/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/9/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus5h 30m012:25 AMPisaParking Aurelia5:55 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/9/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/9/2026 5:55:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 5h 30m
Fastest Buses Monday
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m01:25 PMPisaParking Aurelia6:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 1:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 6:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus5h 30m012:25 AMPisaParking Aurelia5:55 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 5:55:00 AM. 50 Economy ticket for $16 per person are available. Travel duration is 5h 30m
-
FlixBus5h 40m05:20 PMPisaParking Aurelia11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/10/2026 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/10/2026 11:00:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 5h 40m
Fastest Buses Tuesday
-
FlixBus6h 5m07:15 AMPisaParking Aurelia1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/11/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/11/2026 1:20:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 5m
-
FlixBus6h 15m05:20 PMPisaParking Aurelia11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/11/2026 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/11/2026 11:35:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 6h 15m
Fastest Buses Wednesday
-
FlixBus4h 35m010:00 PMPisaParking Aurelia2:35 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 10:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 2:35:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 35m
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/12/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/12/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus6h 5m012:00 PMPisaParking Aurelia6:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/12/2026 12:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 2/12/2026 6:05:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 6h 5m
Fastest Buses Thursday
-
FlixBus4h 45m06:05 AMPisaParking Aurelia10:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
-
FlixBus5h 10m05:25 PMPisaParking Aurelia10:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 10:35:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
-
FlixBus5h 30m012:25 AMPisaParking Aurelia5:55 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/13/2026 5:55:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 30m
-
FlixBus6h 5m012:00 PMPisaParking Aurelia6:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 2/13/2026 12:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 2/13/2026 6:05:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 6h 5m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Pisa to Rome
What are the most popular stations in Pisa and Rome?
In Pisa, you will usually depart from Central Bus Station, Pietrasantina Bus Station or Central Station, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Pisa? With 5 connections between 4 Carpool, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Pisa and Rome, you can pay as low as $14 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Trenitalia: you will get to Rome in just 2h 56m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Pisa and Rome are FlixBus, Trenitalia and MarinoBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Pisa and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Pisa Airport or to Settebagni, and look at flights from Pisa Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Pisa to Rome?
The most popular companies between Pisa and Rome, are FlixBus, Trenitalia and MarinoBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and MarinoBus
Train companies: Trenitalia
All you need to know when you travel from Pisa to Rome
Check all information on comfort and services on all modes of transports from Pisa to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Pisa to Rome
How can I reach Rome from Pisa?
Every day, there are on average 5 connections between Carpool, Train and Bus, with which you can get to Rome from Pisa.
How far is Rome from Pisa?
The distance between Pisa and Rome is 164.7 miles.
What is the most ecofriendly mode of transport between Pisa and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 7 kgs of CO2, a train 9 kgs, a car 45 kgs, and a flight 65 kgs.
What is the cheapest mode of transport from Pisa to Rome?
You can get to Rome with just $14 by taking a Bus from FlixBus.
What is the fastest way to get from Pisa to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 2h 56m with a Train from Trenitalia.
More routes to Pisa and to Rome
Looking for more options? Here you can see the most popular routes to Pisa and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Pisa
- Bologna to Pisa
- Catania to Pisa
- Florence to Pisa
- Geneva to Pisa
- Genoa to Pisa
- La Spezia to Pisa
- Lucca to Pisa
- Milan Malpensa Airport to Pisa
- Milan to Pisa
- Modena to Pisa
- Naples to Pisa
- Parma to Pisa
- Pescara to Pisa
- Prato to Pisa
- Rome Fiumicino Airport to Pisa
- Rome to Pisa
- Sala Consilina to Pisa
- Salerno to Pisa
- Siena to Pisa
- Turin to Pisa
- Venice to Pisa
- Zurich to Pisa
- Trips to Rome
- Caserta to Rome
- Catania to Rome
- Civitanova to Rome
- Civitavecchia to Rome
- Como to Rome
- Cosenza to Rome
- Florence to Rome
- Frascineto to Rome
- Grottaminarda to Rome
- Grottammare to Rome
- L'Aquila to Rome
- Lanciano to Rome
- Messina to Rome
- Meta to Rome
- Milan to Rome
- Naples to Rome
- Palermo to Rome
- Porto D'Ascoli to Rome
- Porto San Giorgio to Rome
- Prague Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Vibo Valentia to Rome
