Bus Pisa to Rome - Compare all Companies

Compare all timetables for the bus from Pisa to Rome

Here is a selection of the cheapest bus trips from the schedule from Pisa to Rome from various bus operators like FlixBus, MarinoBus or Busitalia Rail Service for the next days.

today

$19

tomorrow

$18

Friday

$19

Saturday

$18

Sunday

$18

Monday

$15

Tuesday

$16

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
MarinoBus	6h 0m	8:20 AM	Pisa	Pietrasantina Bus Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$19	A Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 4/29/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/29/2026 2:20:00 PM. 50 Basic ticket for $19 per person are available. Travel duration is 6h 0m
FlixBus	6h 5m	7:15 AM	Pisa	Pietrasantina Bus Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$30	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 4/29/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/29/2026 1:20:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 5m
FlixBus	5h 50m	5:10 PM	Pisa	Pietrasantina Bus Station	11:00 PM	Rome	Tiburtina Bus Station	Economy	$38	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 4/29/2026 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/29/2026 11:00:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 5h 50m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 45m	6:05 AM	Pisa	Parking Aurelia	10:50 AM	Rome	Tiburtina Bus Station	Economy	$18	A Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 4/30/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/30/2026 10:50:00 AM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 45m
MarinoBus	6h 0m	8:20 AM	Pisa	Pietrasantina Bus Station	2:20 PM	Rome	Tiburtina Bus Station	Economy	$19	A Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 4/30/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/30/2026 2:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 0m
FlixBus	6h 5m	7:15 AM	Pisa	Pietrasantina Bus Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$29	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 4/30/2026 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/30/2026 1:20:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 6h 5m
FlixBus	6h 5m	12:00 PM	Pisa	Pietrasantina Bus Station	6:05 PM	Rome	Anagnina Bus Station	Economy	$52	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 4/30/2026 12:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 4/30/2026 6:05:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 6h 5m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
MarinoBus	6h 0m	8:20 AM	Pisa	Pietrasantina Bus Station	2:20 PM	Rome	Tiburtina Bus Station	Economy	$19	A Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/1/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/1/2026 2:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 0m
FlixBus	4h 35m	10:00 PM	Pisa	Pietrasantina Bus Station	2:35 AM	Rome	Tiburtina Bus Station	Economy	$21	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/1/2026 10:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 2:35:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 4h 35m
FlixBus	5h 10m	1:25 PM	Pisa	Pietrasantina Bus Station	6:35 PM	Rome	Tiburtina Bus Station	Economy	$26	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/1/2026 1:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/1/2026 6:35:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 5h 10m
Busitalia Rail Service	4h 14m	7:45 PM	Pisa	Pietrasantina Bus Station	11:59 PM	Rome	Tiburtina Bus Station	Basic	$32	A Bus from Busitalia Rail Service goes from Pietrasantina Bus Station, Pisa (Italy) at 5/1/2026 7:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/1/2026 11:59:00 PM. 50 Basic ticket for $32 per person are available. Travel duration is 4h 14m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 45m	6:05 AM	Pisa	Parking Aurelia	10:50 AM	Rome	Tiburtina Bus Station	Economy	$18	A Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 5/2/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 10:50:00 AM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 45m
MarinoBus	6h 0m	8:20 AM	Pisa	Pietrasantina Bus Station	2:20 PM	Rome	Tiburtina Bus Station	Economy	$19	A Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/2/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 2:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 0m
FlixBus	4h 35m	10:00 PM	Pisa	Pietrasantina Bus Station	2:35 AM	Rome	Tiburtina Bus Station	Economy	$20	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/2/2026 10:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/3/2026 2:35:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 4h 35m
FlixBus	5h 10m	5:25 PM	Pisa	Pietrasantina Bus Station	10:35 PM	Rome	Tiburtina Bus Station	Economy	$21	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/2/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/2/2026 10:35:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 10m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 45m	6:05 AM	Pisa	Parking Aurelia	10:50 AM	Rome	Tiburtina Bus Station	Economy	$18	A Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 5/3/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/3/2026 10:50:00 AM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 45m
MarinoBus	6h 0m	8:20 AM	Pisa	Pietrasantina Bus Station	2:20 PM	Rome	Tiburtina Bus Station	Economy	$19	A Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/3/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/3/2026 2:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 0m
FlixBus	5h 30m	12:25 AM	Pisa	Pietrasantina Bus Station	5:55 AM	Rome	Tiburtina Bus Station	Economy	$30	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/3/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/3/2026 5:55:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 5h 30m
Busitalia Rail Service	4h 14m	7:45 PM	Pisa	Pietrasantina Bus Station	11:59 PM	Rome	Tiburtina Bus Station	Basic	$32	A Bus from Busitalia Rail Service goes from Pietrasantina Bus Station, Pisa (Italy) at 5/3/2026 7:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/3/2026 11:59:00 PM. 50 Basic ticket for $32 per person are available. Travel duration is 4h 14m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 45m	6:05 AM	Pisa	Parking Aurelia	10:50 AM	Rome	Tiburtina Bus Station	Economy	$15	A Bus from FlixBus goes from Parking Aurelia, Pisa (Italy) at 5/4/2026 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/4/2026 10:50:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 45m
FlixBus	5h 10m	5:25 PM	Pisa	Pietrasantina Bus Station	10:35 PM	Rome	Tiburtina Bus Station	Economy	$17	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/4/2026 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/4/2026 10:35:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 5h 10m
FlixBus	4h 35m	10:00 PM	Pisa	Pietrasantina Bus Station	2:35 AM	Rome	Tiburtina Bus Station	Economy	$18	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/4/2026 10:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/5/2026 2:35:00 AM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 35m
MarinoBus	6h 0m	8:20 AM	Pisa	Pietrasantina Bus Station	2:20 PM	Rome	Tiburtina Bus Station	Economy	$19	A Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/4/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/4/2026 2:20:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 6h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 10m	1:25 PM	Pisa	Pietrasantina Bus Station	6:35 PM	Rome	Tiburtina Bus Station	Economy	$16	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/5/2026 1:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/5/2026 6:35:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 5h 10m
MarinoBus	6h 0m	8:20 AM	Pisa	Pietrasantina Bus Station	2:20 PM	Rome	Tiburtina Bus Station	Economy	$18	A Bus from MarinoBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/5/2026 8:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/5/2026 2:20:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 6h 0m
FlixBus	5h 30m	12:25 AM	Pisa	Pietrasantina Bus Station	5:55 AM	Rome	Tiburtina Bus Station	Economy	$20	A Bus from FlixBus goes from Pietrasantina Bus Station, Pisa (Italy) at 5/5/2026 12:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 5/5/2026 5:55:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 30m
Busitalia Rail Service	4h 14m	7:45 PM	Pisa	Pietrasantina Bus Station	11:59 PM	Rome	Tiburtina Bus Station	Economy	$32	A Bus from Busitalia Rail Service goes from Pietrasantina Bus Station, Pisa (Italy) at 5/5/2026 7:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 5/5/2026 11:59:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 4h 14m

Best Price Offer: The price for the cheapest bus from Pisa to Rome is $15 on 5/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Pisa and Rome

See here how frequent the connections between Pisa and Rome are, during different times and days of the week.

Sunday is the busiest day, with more than 16 daily buses from Pisa to Rome. Wednesday has instead the fewest connections, with only 7 daily coaches between Pisa and Rome.

The busiest time of the day is the Morning, with 47 buses from Pisa to Rome, while Night sees the fewest connections between Pisa and Rome, with 6 offers.

Facts about the bus from Pisa to Rome

Compare all providers like FlixBus, MarinoBus and Busitalia Rail Service that travel 12 times every day by bus from Pisa to Rome in one click! Book your bus ticket from Pisa to Rome starting from $15!

Cheapest Bus	$15
Fastest Bus	4h 14m
Earliest Bus	7:15 AM
Latest Bus	7:45 PM
Daily Bus Routes	12 Ø
Distance	164.7 miles
Bus Companies	FlixBus, MarinoBus, Busitalia Rail Service and Busitalia Fast

Cheapest bus connections from Pisa to Rome

Every day, 12 buses from 4 bus companies leave Pisa for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/29/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

Tuesday 04/28

Wednesday 04/29

$19

Thursday 04/30

$18

Friday 05/01

$20

Saturday 05/02

$18

Sunday 05/03

$18

Monday 05/04

$15

Tuesday 05/05

$16

Wednesday 05/06

$20

Thursday 05/07

$15

Friday 05/08

$15

Saturday 05/09

$15

Sunday 05/10

$15

Monday 05/11

$15

Tuesday 05/12

$15

Wednesday 05/13

$22

Thursday 05/14

$28

Friday 05/15

$15

Saturday 05/16

$15

Sunday 05/17

$15

Monday 05/18

$15

Tuesday 05/19

$15

Wednesday 05/20

$24

Thursday 05/21

$15

Friday 05/22

$15

Saturday 05/23

The cheapest time to travel from Pisa to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Pisa to Rome, for the next 30 days.

With a price starting from $15, Monday is the cheapest day for a bus from Pisa to Rome. Wednesday instead is the most expensive day with prices starting from $19.

Morning is the cheapest day time for bus tickets from Pisa to Rome, with $15. Evening is the most expensive time of the day with prices starting from $18.

How to save money travelling from Pisa to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pisa to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pisa to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Pisa to Rome are also emptier.

All bus stations and stops in Pisa and Rome

In the map below, you can see where to find all bus stations in Pisa and Rome.

Pietrasantina Bus Station

Via Pietrasantina

Central Bus Station

V.Brennero Porta A Lucca

Navacchio Station

Ospedale Cisanello Bus Stop

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Fori Imperiali Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Pisa to Rome? Compare all modes of transports from Pisa to Rome.

Service and Comfort on the bus from Pisa to Rome

Want to know which seat classes are available on the buses from Pisa to Rome? Or which bus companies serve the route Pisa to Rome? Below you will find answers to your questions.

FAQs about the Pisa to Rome bus

How much does a Pisa Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $15 and takes 4h 45m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Pisa to Rome?

This route is offered by 4 companies with a range of ticket prices between $15 and $85. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Pisa to Rome each day?

Every day, the Pisa to Rome bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Pisa to Rome take?

The fastest bus from Pisa to Rome is offered by Busitalia Fast and takes 4h 14m. Bus tickets for this connection cost $33. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Pisa to Rome?

The earliest bus arriving in Rome from Pisa starts at 7:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Pisa to Rome?

The latest bus trip departing from Pisa for Rome starts at 7:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Pisa Rome route?

When traveling by bus from Pisa to Rome, passengers can travel with FlixBus, MarinoBus and Busitalia Rail Service. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Pisa and Rome?

You can check all the direct connections between Pisa and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, MarinoBus and Busitalia Rail Service.

What can I take with me on the Pisa to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Pisa Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Pisa Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pisa to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Pisa to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between Pisa and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Pisa to Rome?

Prices and availability for 12 trips between Pisa and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Pisa to Rome

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pisa and to Rome

Here’s an overview of the most popular bus routes to Pisa and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!