Bus Palermo to Rome - Compare all Companies

Compare all timetables for the bus from Palermo to Rome

Here is a selection of the cheapest bus trips from the schedule from Palermo to Rome from various bus operators like FlixBus, Autoservizi Salemi or Itabus for the next days.

today

$70

tomorrow

$65

Thursday

$38

Friday

$52

Saturday

$47

Sunday

$41

Monday

$47

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autoservizi Salemi	12h 15m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	6:15 AM	Rome	Tiburtina Bus Station	Basic	$70	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/16/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/17/2025 6:15:00 AM. 50 Basic ticket for $70 per person are available. Travel duration is 12h 15m
FlixBus	16h 45m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	8:10 AM	Rome	Tiburtina Bus Station	Economy	$88	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/16/2025 3:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/17/2025 8:10:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 16h 45m
FlixBus	18h 25m	11:10 AM	Palermo	Via Tommaso Fazello Bus Stop	5:35 AM	Rome	Tiburtina Bus Station	Economy	$89	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/16/2025 11:10:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/17/2025 5:35:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 25m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	16h 45m	3:25 PM	Palermo	Via Tommaso Fazello Bus Stop	8:10 AM	Rome	Tiburtina Bus Station		Economy	$65	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/17/2025 3:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 8:10:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 45m
	Autoservizi Salemi	12h 15m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	6:15 AM	Rome	Tiburtina Bus Station		Basic	$71	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/17/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 6:15:00 AM. 50 Basic ticket for $71 per person are available. Travel duration is 12h 15m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	13h 55m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	7:05 AM	Rome	Tiburtina Bus Station		Economy	$38	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/18/2025 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 7:05:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 13h 55m
	Autoservizi Salemi	12h 15m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	6:15 AM	Rome	Tiburtina Bus Station		Basic	$70	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/18/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 6:15:00 AM. 50 Basic ticket for $70 per person are available. Travel duration is 12h 15m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	7:05 AM	Rome	Tiburtina Bus Station	Economy	$52	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/19/2025 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 7:05:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	12h 15m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	6:15 AM	Rome	Tiburtina Bus Station	Basic	$70	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/19/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 6:15:00 AM. 50 Basic ticket for $70 per person are available. Travel duration is 12h 15m
FlixBus	18h 25m	11:10 AM	Palermo	Via Tommaso Fazello Bus Stop	5:35 AM	Rome	Tiburtina Bus Station	Economy	$83	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/19/2025 11:10:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 5:35:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 25m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 25m	8:00 PM	Palermo	Via Fazello	9:25 AM	Rome	Tiburtina Bus Station	Premium Economy	$47	A Bus from Itabus goes from Via Fazello, Palermo (Italy) at 12/20/2025 8:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 9:25:00 AM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 13h 25m
FlixBus	13h 55m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	7:05 AM	Rome	Tiburtina Bus Station	Economy	$62	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/20/2025 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:05:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 13h 55m
FlixBus	13h 55m	5:25 PM	Palermo	Via Tommaso Fazello Bus Stop	7:20 AM	Rome	Tiburtina Bus Station	Economy	$62	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/20/2025 5:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:20:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	12h 15m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	6:15 AM	Rome	Tiburtina Bus Station	Basic	$70	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/20/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 6:15:00 AM. 50 Basic ticket for $70 per person are available. Travel duration is 12h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 25m	8:00 PM	Palermo	Via Fazello	9:25 AM	Rome	Tiburtina Bus Station	Premium Economy	$41	A Bus from Itabus goes from Via Fazello, Palermo (Italy) at 12/21/2025 8:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 9:25:00 AM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 13h 25m
FlixBus	13h 55m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	7:05 AM	Rome	Tiburtina Bus Station	Economy	$68	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/21/2025 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 7:05:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	12h 15m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	6:15 AM	Rome	Tiburtina Bus Station	Basic	$70	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/21/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 6:15:00 AM. 50 Basic ticket for $70 per person are available. Travel duration is 12h 15m
FlixBus	18h 25m	11:10 AM	Palermo	Via Tommaso Fazello Bus Stop	5:35 AM	Rome	Tiburtina Bus Station	Economy	$89	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/21/2025 11:10:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 5:35:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 25m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 25m	8:00 PM	Palermo	Piazza Cairoli Bus Station	9:25 AM	Rome	Tiburtina Bus Station	Economy	$47	A Bus from Itabus goes from Piazza Cairoli Bus Station, Palermo (Italy) at 12/22/2025 8:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 9:25:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 13h 25m
FlixBus	13h 55m	5:10 PM	Palermo	Via Tommaso Fazello Bus Stop	7:05 AM	Rome	Tiburtina Bus Station	Economy	$68	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/22/2025 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 7:05:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	12h 15m	6:00 PM	Palermo	Via Tommaso Fazello Bus Stop	6:15 AM	Rome	Tiburtina Bus Station	Basic	$69	A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/22/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 6:15:00 AM. 50 Basic ticket for $69 per person are available. Travel duration is 12h 15m
FlixBus	18h 25m	11:10 AM	Palermo	Via Tommaso Fazello Bus Stop	5:35 AM	Rome	Tiburtina Bus Station	Economy	$83	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 12/22/2025 11:10:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 5:35:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 25m

Best Price Offer: The price for the cheapest bus from Palermo to Rome is $38 on 12/18/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Palermo and Rome

See here how frequent the connections between Palermo and Rome are, during different times and days of the week.

Saturday is the busiest day, with more than 12 daily buses from Palermo to Rome. Wednesday has instead the fewest connections, with only 2 daily coaches between Palermo and Rome.

The busiest time of the day is the Evening, with 28 buses from Palermo to Rome, while Morning sees the fewest connections between Palermo and Rome, with 5 offers.

Facts about the bus from Palermo to Rome

Compare all providers like FlixBus, Autoservizi Salemi and Itabus that travel 6 times every day by bus from Palermo to Rome in one click! Book your bus ticket from Palermo to Rome starting from $38!

Cheapest Bus	$38
Fastest Bus	12h 15m
Earliest Bus	11:10 AM
Latest Bus	8:00 PM
Daily Bus Routes	6 Ø
Distance	265.6 miles
Bus Companies	FlixBus, Autoservizi Salemi and Itabus

Cheapest bus connections from Palermo to Rome

Every day, 6 buses from 3 bus companies leave Palermo for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

$70

Wednesday 12/17

$71

Thursday 12/18

$71

Friday 12/19

$52

Saturday 12/20

$41

Sunday 12/21

$41

Monday 12/22

$41

Tuesday 12/23

$68

Wednesday 12/24

$80

Thursday 12/25

$70

Friday 12/26

$70

Saturday 12/27

$89

Sunday 12/28

$76

Monday 12/29

$72

Tuesday 12/30

$87

Wednesday 12/31

$66

Thursday 01/01

$71

Friday 01/02

$88

Saturday 01/03

$98

Sunday 01/04

$100

Monday 01/05

$96

Tuesday 01/06

$87

Wednesday 01/07

$100

Thursday 01/08

Friday 01/09

$45

Saturday 01/10

The cheapest time to travel from Palermo to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Palermo to Rome, for the next 30 days.

With a price starting from $37, Saturday is the cheapest day for a bus from Palermo to Rome. Tuesday instead is the most expensive day with prices starting from $68.

Afternoon is the cheapest day time for bus tickets from Palermo to Rome, with $38. Morning is the most expensive time of the day with prices starting from $79.

How to save money travelling from Palermo to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Palermo to Rome are also emptier.

Beloved bus companies from Palermo to Rome

These are the most booked bus companies between Palermo to Rome from our users.

Autoservizi Salemi from Palermo to Rome

Here you will find the key facts about the Autoservizi Salemi bus route Palermo to Rome:

Cheapest Price	$69
Fastest Bus	12h 15m
Earliest Bus	6:00 PM
Last Bus	6:00 PM
Daily Connections	2 Ø
Found on	12/16/2025

Latest reviews for bus companies on the route Palermo - Rome

Noemi, 9/4/2025

Viaggio con Salemi autobus da diversi mesi, circa una volta al mese, e mi trovo sempre benissimo! 🚍✨ I pullman sono comodi e puntuali, dotati di televisione e di un bagno sempre perfettamente funzion ... Viaggio con Salemi autobus da diversi mesi, circa una volta al mese, e mi trovo sempre benissimo! 🚍✨ I pullman sono comodi e puntuali, dotati di televisione e di un bagno sempre perfettamente funzionante: pulito, con carta igienica, sapone e specchio pronti all’uso (cosa non scontata nei viaggi lunghi, e che con Salemi non mi è mai mancata!). Salemi è stato l’ultimo autobus che ho provato, prima viaggiavo con Flixbus o Itabus, ma non c’è paragone, infatti sono viaggiatrice fissa con voi. Non ho mai trovato il bagno inagibile, sempre tutto curato nei minimi dettagli. Un punto di forza incredibile sono gli autisti: simpatici, cordiali e professionali, riescono a rendere il viaggio non solo confortevole ma anche piacevole. Offrono anche una bottiglia d’acqua di benvenuto ogni volta. Un servizio davvero affidabile e impeccabile, per me ormai una garanzia. Complimenti a tutto lo staff Salemi, continuate così! 👏😊

All bus stations and stops in Palermo and Rome

In the map below, you can see where to find all bus stations in Palermo and Rome.

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Rome? Compare all modes of transports from Palermo to Rome.

Service and Comfort on the bus from Palermo to Rome

Want to know which seat classes are available on the buses from Palermo to Rome? Or which bus companies serve the route Palermo to Rome? Below you will find answers to your questions.

FAQs about the Palermo to Rome bus

How much does a Palermo Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $38 and takes 13h 55m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Palermo to Rome?

This route is offered by 3 companies with a range of ticket prices between $38 and $89. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Palermo to Rome each day?

Every day, the Palermo to Rome bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Palermo to Rome take?

The fastest bus from Palermo to Rome is offered by Autoservizi Salemi and takes 12h 15m. Bus tickets for this connection cost $70. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Palermo to Rome?

The earliest bus arriving in Rome from Palermo starts at 11:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Palermo to Rome?

The latest bus trip departing from Palermo for Rome starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Palermo Rome route?

When traveling by bus from Palermo to Rome, passengers can travel with FlixBus, Autoservizi Salemi and Itabus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Palermo and Rome?

You can check all the direct connections between Palermo and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Autoservizi Salemi and Itabus.

What can I take with me on the Palermo to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Palermo Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Palermo to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Palermo and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Palermo to Rome?

Prices and availability for 6 trips between Palermo and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Palermo to Rome

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Palermo and to Rome

Here’s an overview of the most popular bus routes to Palermo and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!