Bus from Palermo to Rome from $53

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Compare all timetables for the bus from Palermo to Rome

Here is a selection of the cheapest bus trips from the schedule from Palermo to Rome from various bus operators like FlixBus or Autoservizi Salemi for the next days.
today
from $53
tomorrow
from $66
Sunday
from $66
Monday
from $65
Tuesday
from $68
Wednesday
from $66
Thursday
from $59

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    13h 55m
    0
    5:10 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    7:05 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    18h 25m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    12:40 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $87
  • FlixBus
    13h 55m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    8:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $88
  • FlixBus
    20h 10m
    0
    9:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:20 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $109
  • FlixBus
    18h 25m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $120

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    13h 55m
    0
    5:10 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    7:05 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $66
  • FlixBus
    18h 25m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $81
  • FlixBus
    18h 25m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    12:40 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $84
  • FlixBus
    13h 55m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    8:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $112
  • FlixBus
    20h 10m
    0
    9:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:20 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $116

Cheapest bus trips Sunday

Prices are for one way and one person
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $66
  • FlixBus
    18h 25m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    12:40 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $96
  • FlixBus
    13h 55m
    0
    5:10 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    7:05 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $110
  • FlixBus
    18h 25m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $113

Cheapest bus trips Monday

Prices are for one way and one person
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $65
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $66
  • FlixBus
    18h 25m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $96
  • FlixBus
    13h 55m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    8:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $105
  • FlixBus
    16h 45m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    8:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $107
  • Did you know that if you travel from Palermo to Rome via Caserta, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      17h 30m
      0
      3:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      4:34 AM
      Caserta
      Caserta Nord Nazionale Appia Bus Stop
      0
      FlixBus
      Economy
      $44
      • Waiting Time 1h 47m
    • Distribusion
      2h 34m
      0
      6:21 AM
      Caserta
      Train Station
      8:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $10
    Travel time is 5h 30m longer, but you will save $11

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $68
  • FlixBus
    15h 35m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $94
  • FlixBus
    18h 25m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $105
  • FlixBus
    18h 25m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    12:40 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $112
  • Did you know that if you travel from Palermo to Rome via Caserta, you can save more than $14? You can find the corresponding connections below.
    • FlixBus
      17h 30m
      0
      3:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      4:34 AM
      Caserta
      Caserta Nord Nazionale Appia Bus Stop
      0
      FlixBus
      Economy
      $44
      • Waiting Time 1h 47m
    • Distribusion
      2h 34m
      0
      6:21 AM
      Caserta
      Train Station
      8:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $10
    Travel time is 5h 30m longer, but you will save $14

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $66
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $66
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $66
  • FlixBus
    15h 35m
    0
    3:25 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $84
  • FlixBus
    18h 25m
    0
    11:10 AM
    Palermo
    Via Tommaso Fazello Bus Stop
    5:35 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $87
  • Did you know that if you travel from Palermo to Rome via Caserta, you can save more than $12? You can find the corresponding connections below.
    • FlixBus
      17h 30m
      0
      3:25 PM
      Palermo
      Via Tommaso Fazello Bus Stop
      4:34 AM
      Caserta
      Caserta Nord Nazionale Appia Bus Stop
      0
      FlixBus
      Economy
      $44
      • Waiting Time 1h 47m
    • Distribusion
      2h 34m
      0
      6:21 AM
      Caserta
      Train Station
      8:55 AM
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      $10
    Travel time is 5h 30m longer, but you will save $12

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    18h 25m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    12:40 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $59
  • FlixBus
    13h 55m
    0
    5:10 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    7:05 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $61
  • Autoservizi Salemi
    12h 0m
    0
    6:00 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    6:00 AM
    Rome
    Tiburtina Bus Station
    0
    Autoservizi Salemi
    Economy
    $66
  • FlixBus
    13h 55m
    0
    6:15 PM
    Palermo
    Via Tommaso Fazello Bus Stop
    8:10 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $74

Frequency of bus connections between Palermo and Rome

See here how frequent the connections between Palermo and Rome are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from Palermo to Rome. Monday has instead the fewest connections, with only 5 daily coaches between Palermo and Rome.
The busiest time of the day is the Evening, with 20 buses from Palermo to Rome, while Afternoon sees the fewest connections between Palermo and Rome, with 7 offers.

Facts about the bus from Palermo to Rome

Compare all providers like FlixBus and Autoservizi Salemi that travel 5 times every day by bus from Palermo to Rome in one click! Book your bus ticket from Palermo to Rome starting from $53!

Cheapest Bus $53
Fastest Bus 12h 0m
Earliest Bus 9:10 AM
Latest Bus 6:15 PM
Daily Bus Routes 5 Ø
Distance 265.6 miles
Bus Companies FlixBus and Autoservizi Salemi

Cheapest bus connections from Palermo to Rome

Every day, 5 buses from 2 bus companies leave Palermo for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
$53
Saturday 06/21
$66
Sunday 06/22
$96
Monday 06/23
$96
Tuesday 06/24
$94
Wednesday 06/25
$84
Thursday 06/26
$59
Friday 06/27
$46
Saturday 06/28
$42
Sunday 06/29
$66
Monday 06/30
$63
Tuesday 07/01
$57
Wednesday 07/02
$59
Thursday 07/03
$48
Friday 07/04
$30
Saturday 07/05
$30
Sunday 07/06
$46
Monday 07/07
$42
Tuesday 07/08
$57
Wednesday 07/09
$61
Thursday 07/10
$46
Friday 07/11
$34
Saturday 07/12

The cheapest time to travel from Palermo to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Palermo to Rome, for the next 30 days.
With a price starting from $53, Friday is the cheapest day for a bus from Palermo to Rome. Tuesday instead is the most expensive day with prices starting from $68.
Afternoon is the cheapest day time for bus tickets from Palermo to Rome, with $53. Morning is the most expensive time of the day with prices starting from $80.

How to save money travelling from Palermo to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Palermo to Rome are also emptier.

Beloved bus companies from Palermo to Rome

These are the most booked bus companies between Palermo to Rome from our users.

FlixBus from Palermo to Rome

FlixBus

Here you will find the key facts about the FlixBus bus route Palermo to Rome:

Cheapest Price $53
Fastest Bus 13h 55m
Earliest Bus 9:10 AM
Last Bus 6:15 PM
Daily Connections 4 Ø
Found on 6/19/2025

Autoservizi Salemi from Palermo to Rome

Autoservizi Salemi

Here you will find the key facts about the Autoservizi Salemi bus route Palermo to Rome:

Cheapest Price $65
Fastest Bus 12h 0m
Earliest Bus 6:00 PM
Last Bus 6:00 PM
Daily Connections 1 Ø
Found on 6/16/2025

All bus stations and stops in Palermo and Rome

In the map below, you can see where to find all bus stations in Palermo and Rome.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Rome? Compare all modes of transports from Palermo to Rome.

Service and Comfort on the bus from Palermo to Rome

Want to know which seat classes are available on the buses from Palermo to Rome? Or which bus companies serve the route Palermo to Rome? Below you will find answers to your questions.

FAQs about the Palermo to Rome bus

How much does a Palermo Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $53 and takes 13h 55m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Palermo to Rome?

This route is offered by 2 companies with a range of ticket prices between $53 and $162. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Palermo to Rome each day?

Every day, the Palermo to Rome bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Palermo to Rome take?

The fastest bus from Palermo to Rome is offered by Autoservizi Salemi and takes 12h 0m. Bus tickets for this connection cost $66. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Palermo to Rome?

The earliest bus arriving in Rome from Palermo starts at 9:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Palermo to Rome?

The latest bus trip departing from Palermo for Rome starts at 6:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Palermo Rome route?

When traveling by bus from Palermo to Rome, passengers can travel with FlixBus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Palermo and Rome?

You can check all the direct connections between Palermo and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Autoservizi Salemi.

What can I take with me on the Palermo to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Palermo Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Rome on your planned travel date.

Available seat classes which are offered on the bus route Palermo to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Rome

Here’s an overview of the most popular bus routes to Palermo and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Marsala to Palermo Buses from Marsala to Palermo
Bus from Giardini Naxos to Palermo Bus from Giardini Naxos to Palermo
Bus Modica to Palermo Bus Modica to Palermo
Bus Messina to Palermo Bus Messina to Palermo
From Munich to Rome bus From Munich to Rome bus
From Pompei to Rome bus From Pompei to Rome bus
Bus from Vasto to Rome Bus from Vasto to Rome
From Verona to Rome bus From Verona to Rome bus
Popular Airport Shuttles to Palermo and to Rome
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