Compare all timetables for the bus from Siena to Rome
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 1:45 PM | Siena | Central Bus Station | 4:35 PM | Rome | Tiburtina Bus Station | Basic | $7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/28/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/28/2026 4:35:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 4:25 PM | Siena | Central Bus Station | 7:15 PM | Rome | Tiburtina Bus Station | Basic | $9 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/28/2026 4:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/28/2026 7:15:00 PM. 50 Basic ticket for $9 per person are available. Travel duration is 2h 50m
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| FlixBus | 2h 45m | 3:00 PM | Siena | Train Station | 5:45 PM | Rome | Tiburtina Bus Station | Economy | $11 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 1/28/2026 3:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/28/2026 5:45:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 45m
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| FlixBus | 3h 5m | 6:50 AM | Siena | Piazza Antonio Gramsci | 9:55 AM | Rome | Tiburtina Bus Station | Economy | $13 |
A Bus from FlixBus goes from Piazza Antonio Gramsci, Siena (Italy) at 1/28/2026 6:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/28/2026 9:55:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 3h 5m
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| MarinoBus | 3h 15m | 11:05 AM | Siena | Central Bus Station | 2:20 PM | Rome | Tiburtina Bus Station | Basic | $16 |
A Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 1/28/2026 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/28/2026 2:20:00 PM. 50 Basic ticket for $16 per person are available. Travel duration is 3h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 3h 5m | 5:35 AM | Siena | Train Station | 8:40 AM | Rome | Tiburtina Bus Station | Economy | $8 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 1/29/2026 5:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/29/2026 8:40:00 AM. 50 Economy ticket for $8 per person are available. Travel duration is 3h 5m
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| FlixBus | 2h 55m | 7:00 AM | Siena | Train Station | 9:55 AM | Rome | Tiburtina Bus Station | Economy | $8 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 1/29/2026 7:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/29/2026 9:55:00 AM. 50 Economy ticket for $8 per person are available. Travel duration is 2h 55m
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| FlixBus | 2h 40m | 8:45 AM | Siena | Train Station | 11:25 AM | Rome | Tiburtina Bus Station | Economy | $8 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 1/29/2026 8:45:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/29/2026 11:25:00 AM. 50 Economy ticket for $8 per person are available. Travel duration is 2h 40m
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| Itabus | 2h 50m | 5:15 AM | Siena | Train Station | 8:05 AM | Rome | Tiburtina Bus Station | Premium Economy | $12 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 1/29/2026 5:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/29/2026 8:05:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 1:45 PM | Siena | Train Station | 4:35 PM | Rome | Tiburtina Bus Station | Premium Economy | $12 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 1/29/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/29/2026 4:35:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 2h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 9:25 AM | Siena | Central Bus Station | 12:15 PM | Rome | Tiburtina Bus Station | Basic | $7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/30/2026 9:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/30/2026 12:15:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 1:45 PM | Siena | Central Bus Station | 4:35 PM | Rome | Tiburtina Bus Station | Basic | $7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/30/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/30/2026 4:35:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 4:25 PM | Siena | Central Bus Station | 7:15 PM | Rome | Tiburtina Bus Station | Basic | $7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/30/2026 4:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/30/2026 7:15:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 15m | 11:05 AM | Siena | Train Station | 2:20 PM | Rome | Tiburtina Bus Station | Basic | $16 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 1/30/2026 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/30/2026 2:20:00 PM. 50 Basic ticket for $16 per person are available. Travel duration is 3h 15m
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| MarinoBus | 3h 10m | 8:30 PM | Siena | Train Station | 11:40 PM | Rome | Tiburtina Bus Station | Basic | $25 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 1/30/2026 8:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/30/2026 11:40:00 PM. 50 Basic ticket for $25 per person are available. Travel duration is 3h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 6:50 PM | Siena | Central Bus Station | 9:40 PM | Rome | Tiburtina Bus Station | Basic | $7 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/31/2026 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/31/2026 9:40:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 4:25 PM | Siena | Central Bus Station | 7:15 PM | Rome | Tiburtina Bus Station | Basic | $9 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/31/2026 4:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/31/2026 7:15:00 PM. 50 Basic ticket for $9 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 1:45 PM | Siena | Central Bus Station | 4:35 PM | Rome | Tiburtina Bus Station | Basic | $12 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 1/31/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/31/2026 4:35:00 PM. 50 Basic ticket for $12 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 15m | 11:05 AM | Siena | Train Station | 2:20 PM | Rome | Tiburtina Bus Station | Basic | $16 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 1/31/2026 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 1/31/2026 2:20:00 PM. 50 Basic ticket for $16 per person are available. Travel duration is 3h 15m
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| MarinoBus | 3h 10m | 8:30 PM | Siena | Train Station | 11:40 PM | Rome | Tiburtina Bus Station | Basic | $29 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 1/31/2026 8:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 1/31/2026 11:40:00 PM. 50 Basic ticket for $29 per person are available. Travel duration is 3h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 9:25 AM | Siena | Train Station | 12:15 PM | Rome | Tiburtina Bus Station | Premium Economy | $13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 2/2/2026 9:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/2/2026 12:15:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 1:45 PM | Siena | Train Station | 4:35 PM | Rome | Tiburtina Bus Station | Premium Economy | $13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 2/2/2026 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/2/2026 4:35:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 4:25 PM | Siena | Train Station | 7:15 PM | Rome | Tiburtina Bus Station | Premium Economy | $13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 2/2/2026 4:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/2/2026 7:15:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 2h 50m
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| MarinoBus | 3h 15m | 11:05 AM | Siena | Central Bus Station | 2:20 PM | Rome | Tiburtina Bus Station | Economy | $15 |
A Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 2/2/2026 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/2/2026 2:20:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 3h 15m
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| MarinoBus | 3h 10m | 8:30 PM | Siena | Train Station | 11:40 PM | Rome | Tiburtina Bus Station | Basic | $25 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 2/2/2026 8:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/2/2026 11:40:00 PM. 50 Basic ticket for $25 per person are available. Travel duration is 3h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 2h 50m | 4:00 AM | Siena | Piazza Antonio Gramsci | 6:50 AM | Rome | Tiburtina Bus Station | Economy | $7 |
A Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 2/3/2026 4:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/3/2026 6:50:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 50m
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| Itabus | 2h 50m | 5:15 AM | Siena | Piazza Antonio Gramsci | 8:05 AM | Rome | Tiburtina Bus Station | Economy | $7 |
A Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 2/3/2026 5:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/3/2026 8:05:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 50m
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| FlixBus | 3h 5m | 5:35 AM | Siena | Train Station | 8:40 AM | Rome | Tiburtina Bus Station | Economy | $7 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 2/3/2026 5:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/3/2026 8:40:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 3h 5m
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| FlixBus | 2h 45m | 9:00 PM | Siena | Train Station | 11:45 PM | Rome | Tiburtina Bus Station | Economy | $7 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 2/3/2026 9:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 2/3/2026 11:45:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 45m
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| MarinoBus | 3h 15m | 11:05 AM | Siena | Train Station | 2:20 PM | Rome | Tiburtina Bus Station | Basic | $16 |
A Bus from MarinoBus goes from Train Station, Siena (Italy) at 2/3/2026 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 2/3/2026 2:20:00 PM. 50 Basic ticket for $16 per person are available. Travel duration is 3h 15m
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Best Price Offer: The price for the cheapest bus from Siena to Rome is $6 on 2/6/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Siena and Rome
Facts about the bus from Siena to Rome
Compare all providers like Itabus, MarinoBus and FlixBus that travel 24 times every day by bus from Siena to Rome in one click! Book your bus ticket from Siena to Rome starting from $6!
| Cheapest Bus | $6 |
| Fastest Bus | 2h 40m |
| Earliest Bus | 6:50 AM |
| Latest Bus | 10:25 PM |
| Daily Bus Routes | 24 Ø |
| Distance | 114.5 miles |
| Bus Companies | Itabus, MarinoBus and FlixBus |
Cheapest bus connections from Siena to Rome
Every day, 24 buses from 3 bus companies leave Siena for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/28/2026 and for the following days.
The cheapest time to travel from Siena to Rome
How to save money travelling from Siena to Rome
Book the ticket from Siena to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siena to Rome are also emptier.Beloved bus companies from Siena to Rome
FlixBus from Siena to Rome
Here you will find the key facts about the FlixBus bus route Siena to Rome:
| Cheapest Price | $7 |
| Fastest Bus | 2h 40m |
| Earliest Bus | 6:50 AM |
| Last Bus | 10:25 PM |
| Daily Connections | 10 Ø |
| Found on | 1/27/2026 |
MarinoBus from Siena to Rome
Here you will find the key facts about the MarinoBus bus route Siena to Rome:
| Cheapest Price | $15 |
| Fastest Bus | 3h 10m |
| Earliest Bus | 11:05 AM |
| Last Bus | 8:30 PM |
| Daily Connections | 7 Ø |
| Found on | 1/27/2026 |
All bus stations and stops in Siena and Rome
In the map below, you can see where to find all bus stations in Siena and Rome.
Compare the bus with other modes of transport
Service and Comfort on the bus from Siena to Rome
FAQs about the Siena to Rome bus
How much does a Siena Rome bus trip cost?
How much could I save by comparing buses from Siena to Rome?
On average, how many connections are available from Siena to Rome each day?
How long does a bus journey from Siena to Rome take?
What time is the first bus from Siena to Rome?
What time is the last bus from Siena to Rome?
Which bus companies operate the Siena Rome route?
Is there a direct bus between Siena and Rome?
What can I take with me on the Siena to Rome bus route?
What equipment is available for the Siena Rome bus route?
How does CheckMyBus find the best bus deals from Siena to Rome?
How does CheckMyBus technology work for trips from Siena to Rome?
Available seat classes which are offered on the bus route Siena to Rome
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Siena and to Rome
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