Bus Siena to Rome: Compare prices and save money

Compare all timetables for the bus from Siena to Rome

Here is a selection of the cheapest bus trips from the schedule from Siena to Rome from various bus operators like Itabus, FlixBus or MarinoBus for the next days.

today

tomorrow

Sunday

Monday

Tuesday

Wednesday

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	12:10 PM	Siena	Train Station	3:00 PM	Rome	Tiburtina Bus Station	Premium Economy	$6	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/5/2025 12:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 3:00:00 PM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	5:15 AM	Siena	Train Station	8:05 AM	Rome	Tiburtina Bus Station	Premium Economy	$8	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/5/2025 5:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 8:05:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 2h 50m
FlixBus	3h 5m	8:15 AM	Siena	Train Station	11:20 AM	Rome	Tiburtina Bus Station	Economy	$10	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/5/2025 8:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 11:20:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 3h 5m
FlixBus	2h 50m	10:30 AM	Siena	Train Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$10	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/5/2025 10:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 1:20:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05 AM	Siena	Train Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$15	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 12/5/2025 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 2:20:00 PM. 50 Basic ticket for $15 per person are available. Travel duration is 3h 15m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	6:50 PM	Siena	Piazza Antonio Gramsci	9:40 PM	Rome	Tiburtina Bus Station	Economy	$9	A Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 12/6/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 9:40:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 50m
FlixBus	2h 50m	7:45 PM	Siena	Train Station	10:35 PM	Rome	Tiburtina Bus Station	Economy	$11	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/6/2025 7:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 10:35:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 50m
FlixBus	2h 45m	9:00 PM	Siena	Train Station	11:45 PM	Rome	Tiburtina Bus Station	Economy	$11	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/6/2025 9:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 11:45:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 2h 45m
Itabus	2h 50m	6:05 AM	Siena	Train Station	8:55 AM	Rome	Tiburtina Bus Station	Premium Economy	$12	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/6/2025 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 8:55:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05 AM	Siena	Train Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$15	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 12/6/2025 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 2:20:00 PM. 50 Basic ticket for $15 per person are available. Travel duration is 3h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	9:00 AM	Siena	Train Station	11:50 AM	Rome	Tiburtina Bus Station	Premium Economy	$6	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/7/2025 9:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 11:50:00 AM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	12:10 PM	Siena	Train Station	3:00 PM	Rome	Tiburtina Bus Station	Premium Economy	$6	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/7/2025 12:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 3:00:00 PM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 50m
FlixBus	2h 45m	10:25 PM	Siena	Train Station	1:10 AM	Rome	Tiburtina Bus Station	Economy	$8	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 10:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 1:10:00 AM. 50 Economy ticket for $8 per person are available. Travel duration is 2h 45m
FlixBus	2h 50m	10:30 AM	Siena	Train Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$10	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 10:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 1:20:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05 AM	Siena	Train Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$15	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 12/7/2025 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 2:20:00 PM. 50 Basic ticket for $15 per person are available. Travel duration is 3h 15m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	5:15 AM	Siena	Train Station	8:05 AM	Rome	Tiburtina Bus Station	Premium Economy	$6	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/8/2025 5:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 8:05:00 AM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	6:05 AM	Siena	Train Station	8:55 AM	Rome	Tiburtina Bus Station	Premium Economy	$6	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/8/2025 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 8:55:00 AM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 50m
FlixBus	2h 55m	7:15 AM	Siena	Train Station	10:10 AM	Rome	Tiburtina Bus Station	Economy	$9	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/8/2025 7:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 10:10:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 55m
FlixBus	3h 5m	7:05 AM	Siena	Piazza Antonio Gramsci	10:10 AM	Rome	Tiburtina Bus Station	Economy	$9	A Bus from FlixBus goes from Piazza Antonio Gramsci, Siena (Italy) at 12/8/2025 7:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 10:10:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 3h 5m
MarinoBus	3h 15m	11:05 AM	Siena	Train Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$15	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 12/8/2025 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 2:20:00 PM. 50 Basic ticket for $15 per person are available. Travel duration is 3h 15m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	2h 45m	6:25 PM	Siena	Train Station	9:10 PM	Rome	Tiburtina Bus Station	Economy	$9	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/9/2025 6:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 9:10:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 45m
Itabus	2h 50m	12:10 PM	Siena	Train Station	3:00 PM	Rome	Tiburtina Bus Station	Premium Economy	$10	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/9/2025 12:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 3:00:00 PM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	1:45 PM	Siena	Train Station	4:35 PM	Rome	Tiburtina Bus Station	Premium Economy	$10	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/9/2025 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 4:35:00 PM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 2h 50m
FlixBus	2h 50m	11:45 AM	Siena	Train Station	2:35 PM	Rome	Tiburtina Bus Station	Economy	$10	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/9/2025 11:45:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 2:35:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05 AM	Siena	Train Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$15	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 12/9/2025 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 2:20:00 PM. 50 Basic ticket for $15 per person are available. Travel duration is 3h 15m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	9:00 AM	Siena	Central Bus Station	11:50 AM	Rome	Tiburtina Bus Station	Basic	$7	A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 12/10/2025 9:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 11:50:00 AM. 50 Basic ticket for $7 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	12:10 PM	Siena	Central Bus Station	3:00 PM	Rome	Tiburtina Bus Station	Basic	$7	A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 12/10/2025 12:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 3:00:00 PM. 50 Basic ticket for $7 per person are available. Travel duration is 2h 50m
FlixBus	3h 5m	8:15 AM	Siena	Train Station	11:20 AM	Rome	Tiburtina Bus Station	Economy	$12	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/10/2025 8:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 11:20:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 5m
FlixBus	2h 50m	10:30 AM	Siena	Train Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$12	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/10/2025 10:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 1:20:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05 AM	Siena	Train Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$15	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 12/10/2025 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 2:20:00 PM. 50 Basic ticket for $15 per person are available. Travel duration is 3h 15m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	2h 50m	1:45 PM	Siena	Train Station	4:35 PM	Rome	Tiburtina Bus Station	Premium Economy	$6	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/11/2025 1:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 4:35:00 PM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 50m
Itabus	2h 50m	6:05 AM	Siena	Train Station	8:55 AM	Rome	Tiburtina Bus Station	Premium Economy	$8	A Bus from Itabus goes from Train Station, Siena (Italy) at 12/11/2025 6:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 8:55:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 2h 50m
FlixBus	2h 50m	10:30 AM	Siena	Train Station	1:20 PM	Rome	Tiburtina Bus Station	Economy	$9	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/11/2025 10:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 1:20:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 50m
FlixBus	2h 50m	7:45 PM	Siena	Train Station	10:35 PM	Rome	Tiburtina Bus Station	Economy	$9	A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/11/2025 7:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 10:35:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 50m
MarinoBus	3h 15m	11:05 AM	Siena	Train Station	2:20 PM	Rome	Tiburtina Bus Station	Basic	$15	A Bus from MarinoBus goes from Train Station, Siena (Italy) at 12/11/2025 11:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 2:20:00 PM. 50 Basic ticket for $15 per person are available. Travel duration is 3h 15m

Best Price Offer: The price for the cheapest bus from Siena to Rome is $6 on 12/5/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Siena and Rome

See here how frequent the connections between Siena and Rome are, during different times and days of the week.

Monday is the busiest day, with more than 71 daily buses from Siena to Rome. Thursday has instead the fewest connections, with only 60 daily coaches between Siena and Rome.

The busiest time of the day is the Morning, with 184 buses from Siena to Rome, while Night sees the fewest connections between Siena and Rome, with 72 offers.

Facts about the bus from Siena to Rome

Compare all providers like Itabus, FlixBus and MarinoBus that travel 65 times every day by bus from Siena to Rome in one click! Book your bus ticket from Siena to Rome starting from $6!

Cheapest Bus	$6
Fastest Bus	2h 40m
Earliest Bus	1:05 AM
Latest Bus	10:25 PM
Daily Bus Routes	65 Ø
Distance	114.5 miles
Bus Companies	Itabus, FlixBus and MarinoBus

Cheapest bus connections from Siena to Rome

Every day, 65 buses from 3 bus companies leave Siena for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

$11

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

Friday 12/12

$12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

$11

Thursday 12/18

$10

Friday 12/19

$13

Saturday 12/20

$12

Sunday 12/21

$12

Monday 12/22

$12

Tuesday 12/23

$30

Wednesday 12/24

$12

Thursday 12/25

Friday 12/26

$13

Saturday 12/27

The cheapest time to travel from Siena to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Siena to Rome, for the next 30 days.

With a price starting from $6, Sunday is the cheapest day for a bus from Siena to Rome. Saturday instead is the most expensive day with prices starting from $9.

Morning is the cheapest day time for bus tickets from Siena to Rome, with $6. Evening is the most expensive time of the day with prices starting from $7.

How to save money travelling from Siena to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Siena to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siena to Rome are also emptier.

Beloved bus companies from Siena to Rome

These are the most booked bus companies between Siena to Rome from our users.

Itabus from Siena to Rome

Here you will find the key facts about the Itabus bus route Siena to Rome:

Cheapest Price	$6
Fastest Bus	2h 50m
Earliest Bus	1:05 AM
Last Bus	6:50 PM
Daily Connections	36 Ø
Found on	12/3/2025

FlixBus from Siena to Rome

Here you will find the key facts about the FlixBus bus route Siena to Rome:

Cheapest Price	$8
Fastest Bus	2h 40m
Earliest Bus	5:35 AM
Last Bus	10:25 PM
Daily Connections	17 Ø
Found on	12/3/2025

All bus stations and stops in Siena and Rome

In the map below, you can see where to find all bus stations in Siena and Rome.

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Siena to Rome? Compare all modes of transports from Siena to Rome.

Service and Comfort on the bus from Siena to Rome

Want to know which seat classes are available on the buses from Siena to Rome? Or which bus companies serve the route Siena to Rome? Below you will find answers to your questions.

FAQs about the Siena to Rome bus

How much does a Siena Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $6 and takes 2h 50m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Siena to Rome?

This route is offered by 3 companies with a range of ticket prices between $6 and $52. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Siena to Rome each day?

Every day, the Siena to Rome bus route is served by approximately 65 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Siena to Rome take?

The fastest bus from Siena to Rome is offered by FlixBus and takes 2h 40m. Bus tickets for this connection cost $11. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Siena to Rome?

The earliest bus arriving in Rome from Siena starts at 1:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Siena to Rome?

The latest bus trip departing from Siena for Rome starts at 10:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Siena Rome route?

When traveling by bus from Siena to Rome, passengers can travel with Itabus, FlixBus and MarinoBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Siena and Rome?

You can check all the direct connections between Siena and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, FlixBus and MarinoBus.

What can I take with me on the Siena to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Siena Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Siena Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siena to Rome on your planned travel date.

Available seat classes which are offered on the bus route Siena to Rome

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Siena and to Rome

Here’s an overview of the most popular bus routes to Siena and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!