Bus from Prague to Rome from $73

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Compare all timetables for the bus from Prague to Rome

Here is a selection of the cheapest bus trips from the schedule from Prague to Rome from various bus operators like FlixBus or RegioJet for the next days.
today
from $82
tomorrow
from $115
Sunday
from $117
Monday
from $73
Tuesday
from $91
Wednesday
from $95
Thursday
from $100

Cheapest bus trips today

Prices are for one way and one person
  • RegioJet
    20h 15m
    0
    6:30 PM
    Prague
    ÚAN Florenc
    2:45 PM
    Rome
    Tiburtina Bus Station
    0
    RegioJet
    Economy
    $82
  • FlixBus
    24h 45m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $125
  • FlixBus
    23h 25m
    0
    11:35 PM
    Prague
    ÚAN Florenc
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $125
  • FlixBus
    28h 15m
    0
    6:45 PM
    Prague
    Wilsonova Bus Station
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $126

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    20h 30m
    0
    2:30 AM
    Prague
    Wilsonova Bus Station
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $115
  • FlixBus
    27h 40m
    0
    5:50 AM
    Prague
    Wilsonova Bus Station
    9:30 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $116
  • FlixBus
    20h 30m
    0
    5:35 PM
    Prague
    Wilsonova Bus Station
    2:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $117
  • FlixBus
    20h 45m
    0
    5:20 PM
    Prague
    ÚAN Florenc
    2:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $117
  • FlixBus
    21h 15m
    0
    4:00 PM
    Prague
    ÚAN Florenc
    1:15 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $117

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    23h 10m
    0
    11:50 PM
    Prague
    Wilsonova Bus Station
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $117
  • FlixBus
    23h 25m
    0
    11:35 PM
    Prague
    ÚAN Florenc
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $117
  • FlixBus
    20h 30m
    0
    5:35 PM
    Prague
    Wilsonova Bus Station
    2:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $120
  • FlixBus
    20h 45m
    0
    5:20 PM
    Prague
    ÚAN Florenc
    2:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $120
  • FlixBus
    20h 0m
    0
    9:25 PM
    Prague
    ÚAN Florenc
    5:25 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $128
  • Did you know that if you travel from Prague to Rome via Udine, you can save more than $19? You can find the corresponding connections below.
    • RegioJet
      23h 35m
      0
      6:30 PM
      Prague
      ÚAN Florenc
      5:05 AM
      Udine
      Train Station
      0
      RegioJet
      Economy
      $55
      • Waiting Time 2h 30m
    • FlixBus
      10h 30m
      0
      7:35 AM
      Udine
      Train Station
      6:05 PM
      Rome
      Anagnina Bus Station
      0
      FlixBus
      Economy
      $44
    Travel time is 3h 35m longer, but you will save $19

Cheapest bus trips Monday

Prices are for one way and one person
  • RegioJet
    20h 15m
    0
    6:30 PM
    Prague
    ÚAN Florenc
    2:45 PM
    Rome
    Tiburtina Bus Station
    0
    RegioJet
    Economy
    $73
  • FlixBus
    24h 45m
    0
    10:15 PM
    Prague
    Na Knížecí Station
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $93
  • FlixBus
    23h 10m
    0
    11:50 PM
    Prague
    Wilsonova Bus Station
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $94
  • FlixBus
    23h 25m
    0
    11:35 PM
    Prague
    ÚAN Florenc
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $94

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    20h 30m
    0
    2:30 AM
    Prague
    Wilsonova Bus Station
    11:00 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $91
  • FlixBus
    27h 40m
    0
    5:50 AM
    Prague
    Wilsonova Bus Station
    9:30 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $92
  • FlixBus
    24h 15m
    0
    9:05 AM
    Prague
    Wilsonova Bus Station
    9:20 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $92
  • FlixBus
    20h 25m
    0
    1:05 PM
    Prague
    Wilsonova Bus Station
    9:30 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $92
  • FlixBus
    20h 30m
    0
    5:35 PM
    Prague
    Wilsonova Bus Station
    2:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $92

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    24h 15m
    0
    9:05 AM
    Prague
    Wilsonova Bus Station
    9:20 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $95
  • FlixBus
    20h 30m
    0
    5:35 PM
    Prague
    Wilsonova Bus Station
    2:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $95
  • FlixBus
    20h 45m
    0
    5:20 PM
    Prague
    ÚAN Florenc
    2:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $95
  • FlixBus
    27h 40m
    0
    5:50 AM
    Prague
    Wilsonova Bus Station
    9:30 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $96
  • FlixBus
    25h 0m
    0
    8:30 AM
    Prague
    Roztyly
    9:30 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $96

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    20h 25m
    0
    1:05 PM
    Prague
    Wilsonova Bus Station
    9:30 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $100
  • FlixBus
    20h 40m
    0
    12:50 PM
    Prague
    ÚAN Florenc
    9:30 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $100
  • FlixBus
    24h 25m
    0
    12:50 PM
    Prague
    Hradčanská
    1:15 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $100
  • FlixBus
    23h 25m
    0
    12:50 PM
    Prague
    ÚAN Florenc
    12:15 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $100
  • FlixBus
    23h 10m
    0
    1:05 PM
    Prague
    Wilsonova Bus Station
    12:15 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $100

Frequency of bus connections between Prague and Rome

See here how frequent the connections between Prague and Rome are, during different times and days of the week.
Saturday is the busiest day, with more than 46 daily buses from Prague to Rome. Wednesday has instead the fewest connections, with only 33 daily coaches between Prague and Rome.
The busiest time of the day is the Afternoon, with 106 buses from Prague to Rome, while Night sees the fewest connections between Prague and Rome, with 19 offers.

Facts about the bus from Prague to Rome

Compare all providers like FlixBus and RegioJet that travel 41 times every day by bus from Prague to Rome in one click! Book your bus ticket from Prague to Rome starting from $73!

Cheapest Bus $73
Fastest Bus 19h 15m
Earliest Bus 2:30 AM
Latest Bus 11:50 PM
Daily Bus Routes 41 Ø
Distance 572.5 miles
Bus Companies FlixBus and RegioJet

Cheapest bus connections from Prague to Rome

Every day, 41 buses from 2 bus companies leave Prague for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
$125
Saturday 06/21
$115
Sunday 06/22
$117
Monday 06/23
$93
Tuesday 06/24
$91
Wednesday 06/25
$95
Thursday 06/26
$100
Friday 06/27
$108
Saturday 06/28
$110
Sunday 06/29
$117
Monday 06/30
$95
Tuesday 07/01
$91
Wednesday 07/02
$100
Thursday 07/03
$103
Friday 07/04
$108
Saturday 07/05
$101
Sunday 07/06
$104
Monday 07/07
$94
Tuesday 07/08
$91
Wednesday 07/09
$94
Thursday 07/10
$92
Friday 07/11
$105
Saturday 07/12

The cheapest time to travel from Prague to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Rome, for the next 30 days.
With a price starting from $73, Monday is the cheapest day for a bus from Prague to Rome. Sunday instead is the most expensive day with prices starting from $117.
Evening is the cheapest day time for bus tickets from Prague to Rome, with $73. Afternoon is the most expensive time of the day with prices starting from $92.

How to save money travelling from Prague to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Rome are also emptier.

All bus stations and stops in Prague and Rome

In the map below, you can see where to find all bus stations in Prague and Rome.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Rome? Compare all modes of transports from Prague to Rome.

Service and Comfort on the bus from Prague to Rome

Want to know which seat classes are available on the buses from Prague to Rome? Or which bus companies serve the route Prague to Rome? Below you will find answers to your questions.

FAQs about the Prague to Rome bus

How much does a Prague Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $73 and takes 20h 15m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Prague to Rome?

This route is offered by 2 companies with a range of ticket prices between $73 and $242. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Prague to Rome each day?

Every day, the Prague to Rome bus route is served by approximately 41 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Rome take?

The fastest bus from Prague to Rome is offered by FlixBus and takes 19h 15m. Bus tickets for this connection cost $157. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Rome?

The earliest bus arriving in Rome from Prague starts at 2:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Rome?

The latest bus trip departing from Prague for Rome starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Rome route?

When traveling by bus from Prague to Rome, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Rome?

You can check all the direct connections between Prague and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Prague to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Rome on your planned travel date.

Available seat classes which are offered on the bus route Prague to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Rome

Here’s an overview of the most popular bus routes to Prague and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Milan to Prague bus From Milan to Prague bus
Buses from Istanbul to Prague Buses from Istanbul to Prague
Bus Budapest - Prague Bus Budapest - Prague
Buses Vienna - Prague Buses Vienna - Prague
Bus to Rome from Amalfi Bus to Rome from Amalfi
Buses Assisi - Rome Buses Assisi - Rome
Buses Milan to Rome Buses Milan to Rome
From Pisa to Rome bus From Pisa to Rome bus
Popular Airport Shuttles to Prague and to Rome
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