Compare all timetables for the bus from Prague to Rome
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 20m | 10:20 PM | Prague | Roztyly | 9:40 PM | Rome | Anagnina Bus Station | Economy | $94 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/5/2025 10:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/6/2025 9:40:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 23h 20m
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| FlixBus | 24h 45m | 10:15 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $106 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/5/2025 10:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 11:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 45m
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| FlixBus | 28h 15m | 6:45 PM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $107 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/5/2025 6:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 11:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 28h 15m
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| FlixBus | 23h 10m | 11:50 PM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $107 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/5/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 11:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 23h 10m
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| FlixBus | 23h 25m | 11:35 PM | Prague | ÚAN Florenc | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $107 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/5/2025 11:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 11:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 23h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 50m | 2:30 PM | Prague | Černý Most | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/6/2025 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 1:20:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 22h 50m
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| FlixBus | 19h 35m | 5:45 PM | Prague | Na Knížecí Station | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/6/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 1:20:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 35m
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| FlixBus | 22h 15m | 3:05 PM | Prague | Zličín | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/6/2025 3:05:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 1:20:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 22h 15m
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| FlixBus | 24h 30m | 12:50 PM | Prague | Hradčanská | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 12/6/2025 12:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 1:20:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 24h 30m
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| FlixBus | 23h 25m | 12:50 PM | Prague | ÚAN Florenc | 12:15 PM | Rome | Anagnina Bus Station | Economy | $88 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/6/2025 12:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/7/2025 12:15:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 23h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 20m | 10:20 PM | Prague | Roztyly | 9:40 PM | Rome | Anagnina Bus Station | Economy | $114 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/7/2025 10:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/8/2025 9:40:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 23h 20m
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| FlixBus | 20h 30m | 2:30 AM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $115 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/7/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 11:00:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 30m
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| FlixBus | 23h 5m | 10:25 AM | Prague | Na Knížecí Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $115 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/7/2025 10:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 9:30:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 23h 5m
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| FlixBus | 19h 35m | 5:45 PM | Prague | Na Knížecí Station | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $116 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/7/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 1:20:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 19h 35m
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| FlixBus | 24h 25m | 12:55 PM | Prague | Zličín | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $116 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/7/2025 12:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 1:20:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 24h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RegioJet | 20h 15m | 6:30 PM | Prague | ÚAN Florenc | 2:45 PM | Rome | Tiburtina Bus Station | Economy | $74 |
A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 12/8/2025 6:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 2:45:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 20h 15m
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| FlixBus | 23h 10m | 11:50 PM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/8/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 11:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 10m
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| FlixBus | 24h 45m | 10:15 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/8/2025 10:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 11:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 24h 45m
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| FlixBus | 23h 25m | 11:35 PM | Prague | ÚAN Florenc | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/8/2025 11:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 11:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 35m | 9:55 AM | Prague | Zličín | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/9/2025 9:55:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 9:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 35m
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| FlixBus | 19h 35m | 5:45 PM | Prague | Na Knížecí Station | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $94 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/9/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 1:20:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 19h 35m
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| FlixBus | 24h 45m | 10:15 PM | Prague | Na Knížecí Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $95 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/9/2025 10:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 11:00:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 24h 45m
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| FlixBus | 24h 20m | 5:45 PM | Prague | Na Knížecí Station | 6:05 PM | Rome | Anagnina Bus Station | Economy | $95 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/9/2025 5:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/10/2025 6:05:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 24h 20m
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| FlixBus | 20h 40m | 9:25 PM | Prague | ÚAN Florenc | 6:05 PM | Rome | Anagnina Bus Station | Economy | $95 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/9/2025 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/10/2025 6:05:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 20h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 50m | 2:30 PM | Prague | Černý Most | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $92 |
A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/10/2025 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 1:20:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 22h 50m
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| FlixBus | 24h 20m | 9:40 AM | Prague | Na Knížecí Station | 10:00 AM | Rome | Tiburtina Bus Station | Economy | $93 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/10/2025 9:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 10:00:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 24h 20m
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| FlixBus | 25h 0m | 8:30 AM | Prague | Roztyly | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $94 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/10/2025 8:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 9:30:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 25h 0m
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| FlixBus | 20h 30m | 5:35 PM | Prague | Wilsonova Bus Station | 2:05 PM | Rome | Tiburtina Bus Station | Economy | $94 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/10/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 2:05:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 30m
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| FlixBus | 19h 35m | 5:45 PM | Prague | Na Knížecí Station | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $94 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/10/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 1:20:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 19h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 50m | 9:40 AM | Prague | Na Knížecí Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $87 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/11/2025 9:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/12/2025 9:30:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 23h 50m
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| FlixBus | 20h 30m | 2:30 AM | Prague | Wilsonova Bus Station | 11:00 PM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/11/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 11:00:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 20h 30m
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| FlixBus | 27h 40m | 5:50 AM | Prague | Wilsonova Bus Station | 9:30 AM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/11/2025 5:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/12/2025 9:30:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 27h 40m
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| FlixBus | 19h 35m | 5:45 PM | Prague | Na Knížecí Station | 1:20 PM | Rome | Tiburtina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/11/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/12/2025 1:20:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 35m
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| FlixBus | 26h 35m | 9:40 AM | Prague | Na Knížecí Station | 12:15 PM | Rome | Anagnina Bus Station | Economy | $88 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/11/2025 9:40:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/12/2025 12:15:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 26h 35m
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Best Price Offer: The price for the cheapest bus from Prague to Rome is $74 on 12/8/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Prague and Rome
Facts about the bus from Prague to Rome
Compare all providers like FlixBus and RegioJet that travel 33 times every day by bus from Prague to Rome in one click! Book your bus ticket from Prague to Rome starting from $74!
| Cheapest Bus | $74 |
| Fastest Bus | 19h 15m |
| Earliest Bus | 2:30 AM |
| Latest Bus | 11:50 PM |
| Daily Bus Routes | 33 Ø |
| Distance | 572.5 miles |
| Bus Companies | FlixBus and RegioJet |
Cheapest bus connections from Prague to Rome
Every day, 33 buses from 2 bus companies leave Prague for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.
The cheapest time to travel from Prague to Rome
How to save money travelling from Prague to Rome
Book the ticket from Prague to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Rome are also emptier.Beloved bus companies from Prague to Rome
FlixBus from Prague to Rome
Here you will find the key facts about the FlixBus bus route Prague to Rome:
| Cheapest Price | $87 |
| Fastest Bus | 19h 15m |
| Earliest Bus | 2:30 AM |
| Last Bus | 11:50 PM |
| Daily Connections | 33 Ø |
| Found on | 12/4/2025 |
All bus stations and stops in Prague and Rome
In the map below, you can see where to find all bus stations in Prague and Rome.
Compare the bus with other modes of transport
Service and Comfort on the bus from Prague to Rome
FAQs about the Prague to Rome bus
How much does a Prague Rome bus trip cost?
How much could I save by comparing buses from Prague to Rome?
On average, how many connections are available from Prague to Rome each day?
How long does a bus journey from Prague to Rome take?
What time is the first bus from Prague to Rome?
What time is the last bus from Prague to Rome?
Which bus companies operate the Prague Rome route?
Is there a direct bus between Prague and Rome?
What can I take with me on the Prague to Rome bus route?
What equipment is available for the Prague Rome bus route?
Available seat classes which are offered on the bus route Prague to Rome
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Prague and to Rome
- Bus Routes to Prague
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- Bus Bern to Prague
- Bus Bled - Prague
- From Bratislava to Prague bus
- Bus to Prague from Brno
- Bus Bucharest - Prague
- Bus Česká Třebová - Prague
- Bus to Prague from Český Krumlov
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- Hamburg to Prague bus
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- From Paris to Prague bus
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- Bus to Prague from Schwandorf
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- Bus from Wroclaw to Prague
- Bus from Zurich to Prague
- Bus Routes to Rome
- Bus Ascoli Piceno to Rome
- Bus Avezzano to Rome
- Bus Bologna to Rome
- From Budapest to Rome bus
- Buses Civitavecchia - Rome
- Bus to Rome from Giulianova
- Bus Lisbon to Rome
- Bus Matera to Rome
- From Meta to Rome bus
- Buses to Rome from Munich
- Buses from Paris to Rome
- Pompei to Rome bus
- Buses Porto San Giorgio to Rome
- Bus from San Salvo Marina to Rome
- Bus from Siena to Rome
- Buses Termoli - Rome
- Buses Vasto - Rome
- Buses Verona to Rome
- Buses to Rome from Villa Rosa
- Buses Zurich to Rome

