Which bus from Prague to Rome is the cheapest?

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Compare all timetables for the bus from Prague to Rome

Here is a selection of the cheapest bus trips from the schedule from Prague to Rome from various bus operators like FlixBus or RegioJet for the next days.

today
$136
tomorrow
$145
Monday
$145
Tuesday
$128
Wednesday
$120
Thursday
$94
Friday
$142

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 20m 10:20 PM Prague Roztyly 9:40 PM Rome Anagnina Bus Station  Economy $136
FlixBus 21h 20m 5:45 PM Prague Na Knížecí Station 3:05 PM Rome Anagnina Bus Station  Economy $151
FlixBus 20h 40m 12:50 PM Prague ÚAN Florenc 9:30 AM Rome Tiburtina Bus Station  Economy $154
FlixBus 20h 25m 1:05 PM Prague Wilsonova Bus Station 9:30 AM Rome Tiburtina Bus Station  Economy $154
FlixBus 22h 0m 8:20 PM Prague Wilsonova Bus Station 6:20 PM Rome Anagnina Bus Station  Economy $154

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 30m 5:35 PM Prague Wilsonova Bus Station 2:05 PM Rome Tiburtina Bus Station  Economy $145
FlixBus 20h 45m 5:20 PM Prague ÚAN Florenc 2:05 PM Rome Tiburtina Bus Station  Economy $145
FlixBus 19h 35m 5:45 PM Prague Na Knížecí Station 1:20 PM Rome Tiburtina Bus Station  Economy $157
FlixBus 24h 25m 12:55 PM Prague Zličín 1:20 PM Rome Tiburtina Bus Station  Economy $158
FlixBus 22h 50m 2:30 PM Prague Černý Most 1:20 PM Rome Tiburtina Bus Station  Economy $160

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 30m 5:35 PM Prague Wilsonova Bus Station 2:05 PM Rome Tiburtina Bus Station  Economy $145
FlixBus 20h 45m 5:20 PM Prague ÚAN Florenc 2:05 PM Rome Tiburtina Bus Station  Economy $145
FlixBus 19h 35m 5:45 PM Prague Na Knížecí Station 1:20 PM Rome Tiburtina Bus Station  Economy $151
FlixBus 22h 50m 2:30 PM Prague Černý Most 1:20 PM Rome Tiburtina Bus Station  Economy $153
FlixBus 22h 15m 3:05 PM Prague Zličín 1:20 PM Rome Tiburtina Bus Station  Economy $155

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 10m 11:50 PM Prague Wilsonova Bus Station 11:00 PM Rome Tiburtina Bus Station  Economy $128
FlixBus 23h 25m 11:35 PM Prague ÚAN Florenc 11:00 PM Rome Tiburtina Bus Station  Economy $128
FlixBus 24h 45m 10:15 PM Prague Na Knížecí Station 11:00 PM Rome Tiburtina Bus Station  Economy $129
FlixBus 21h 50m 5:15 PM Prague ÚAN Florenc 3:05 PM Rome Anagnina Bus Station  Economy $131
FlixBus 23h 20m 10:20 PM Prague Roztyly 9:40 PM Rome Anagnina Bus Station  Economy $131

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 45m 5:20 PM Prague ÚAN Florenc 2:05 PM Rome Tiburtina Bus Station  Economy $120
FlixBus 20h 30m 5:35 PM Prague Wilsonova Bus Station 2:05 PM Rome Tiburtina Bus Station  Economy $120
FlixBus 28h 15m 6:45 PM Prague Wilsonova Bus Station 11:00 PM Rome Tiburtina Bus Station  Economy $122
FlixBus 22h 50m 2:30 PM Prague Černý Most 1:20 PM Rome Tiburtina Bus Station  Economy $123
FlixBus 20h 40m 12:50 PM Prague ÚAN Florenc 9:30 AM Rome Tiburtina Bus Station  Economy $123

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
RegioJet 20h 15m 6:30 PM Prague ÚAN Florenc 2:45 PM Rome Tiburtina Bus Station  Economy $94
FlixBus 20h 30m 5:35 PM Prague Wilsonova Bus Station 2:05 PM Rome Tiburtina Bus Station  Economy $128
FlixBus 20h 45m 5:20 PM Prague ÚAN Florenc 2:05 PM Rome Tiburtina Bus Station  Economy $128
FlixBus 19h 35m 5:45 PM Prague Na Knížecí Station 1:20 PM Rome Tiburtina Bus Station  Economy $136

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 20m 5:45 PM Prague Na Knížecí Station 3:05 PM Rome Anagnina Bus Station  Economy $142
FlixBus 24h 25m 12:55 PM Prague Zličín 1:20 PM Rome Tiburtina Bus Station  Economy $143
FlixBus 22h 50m 2:30 PM Prague Černý Most 1:20 PM Rome Tiburtina Bus Station  Economy $144
FlixBus 19h 35m 5:45 PM Prague Na Knížecí Station 1:20 PM Rome Tiburtina Bus Station  Economy $144
FlixBus 27h 25m 6:05 AM Prague Wilsonova Bus Station 9:30 AM Rome Tiburtina Bus Station  Economy $149

Best Price Offer: The price for the cheapest bus from Prague to Rome is $70 on 1/9/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Prague and Rome

See here how frequent the connections between Prague and Rome are, during different times and days of the week.
Monday is the busiest day, with more than 41 daily buses from Prague to Rome. Wednesday has instead the fewest connections, with only 25 daily coaches between Prague and Rome.
The busiest time of the day is the Afternoon, with 103 buses from Prague to Rome, while Night sees the fewest connections between Prague and Rome, with 5 offers.

Facts about the bus from Prague to Rome

Compare all providers like FlixBus and RegioJet that travel 35 times every day by bus from Prague to Rome in one click! Book your bus ticket from Prague to Rome starting from $70!

Cheapest Bus $70
Fastest Bus 19h 15m
Earliest Bus 11:00 AM
Latest Bus 11:50 PM
Daily Bus Routes 35 Ø
Distance 572.5 miles
Bus Companies FlixBus and RegioJet

Cheapest bus connections from Prague to Rome

Every day, 35 buses from 2 bus companies leave Prague for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/20/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
$151
Sunday 12/21
$145
Monday 12/22
$145
Tuesday 12/23
$128
Wednesday 12/24
$120
Thursday 12/25
$128
Friday 12/26
$142
Saturday 12/27
$132
Sunday 12/28
$128
Monday 12/29
$132
Tuesday 12/30
$128
Wednesday 12/31
$100
Thursday 01/01
$140
Friday 01/02
$125
Saturday 01/03
$122
Sunday 01/04
$117
Monday 01/05
$89
Tuesday 01/06
$84
Wednesday 01/07
$72
Thursday 01/08
$74
Friday 01/09
$70
Saturday 01/10

The cheapest time to travel from Prague to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Rome, for the next 30 days.
With a price starting from $59, Thursday is the cheapest day for a bus from Prague to Rome. Friday instead is the most expensive day with prices starting from $70.
Night is the cheapest day time for bus tickets from Prague to Rome, with $59. Morning is the most expensive time of the day with prices starting from $123.

How to save money travelling from Prague to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Rome are also emptier.

Beloved bus companies from Prague to Rome

These are the most booked bus companies between Prague to Rome from our users.

FlixBus from Prague to Rome

FlixBus

Here you will find the key facts about the FlixBus bus route Prague to Rome:

Cheapest Price $120
Fastest Bus 19h 15m
Earliest Bus 11:00 AM
Last Bus 11:50 PM
Daily Connections 35 Ø
Found on 12/20/2025

All bus stations and stops in Prague and Rome

In the map below, you can see where to find all bus stations in Prague and Rome.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Rome? Compare all modes of transports from Prague to Rome.

Service and Comfort on the bus from Prague to Rome

Want to know which seat classes are available on the buses from Prague to Rome? Or which bus companies serve the route Prague to Rome? Below you will find answers to your questions.

FAQs about the Prague to Rome bus

How much does a Prague Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $70 and takes 20h 15m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Prague to Rome?

This route is offered by 2 companies with a range of ticket prices between $70 and $240. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Prague to Rome each day?

Every day, the Prague to Rome bus route is served by approximately 35 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Rome take?

The fastest bus from Prague to Rome is offered by FlixBus and takes 19h 15m. Bus tickets for this connection cost $178. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Rome?

The earliest bus arriving in Rome from Prague starts at 11:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Rome?

The latest bus trip departing from Prague for Rome starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Rome route?

When traveling by bus from Prague to Rome, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Rome?

You can check all the direct connections between Prague and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Prague to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 35 daily trips between Prague and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Rome?

Prices and availability for 35 trips between Prague and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Rome

Here’s an overview of the most popular bus routes to Prague and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Prague from Brno Bus to Prague from Brno
Buses to Prague from Krakow Buses to Prague from Krakow
From Paris to Prague bus From Paris to Prague bus
Bus Warsaw to Prague Bus Warsaw to Prague
Bus Bologna to Rome Bus Bologna to Rome
Buses Zurich to Rome Buses Zurich to Rome
Bus Bari to Rome Bus Bari to Rome
Buses Barcelona - Rome Buses Barcelona - Rome
Popular Airport Shuttles to Prague and to Rome
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