What is the best way to travel from Prague to Rome?
Looking for a trip? Compare all the available Flights and Buses for the journey to Rome from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Prague?
You can get to Rome with just $49 by taking a Flight from LC Perú, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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LC Perú1h 55m09:10 PMPrague AirportPrague Airport - T1/211:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 9:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/26/2026 11:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 55m
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Ryanair1h 50m07:10 PMPrague AirportPrague Airport - T1/29:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 7:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/26/2026 9:00:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m07:10 PMPrague AirportPrague Airport - T1/29:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 7:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/26/2026 9:00:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 1h 50m
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Smartwings11h 0m06:40 AMPrague AirportPrague Airport - T1/25:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 6:40:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/26/2026 5:40:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 11h 0m
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Buzz4h 50m04:05 PMPrague AirportPrague Airport - T1/28:55 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 4:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/26/2026 8:55:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 4h 50m
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport - T1/21:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/26/2026 1:15:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 55m
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FlixBus22h 30m09:55 PMPragueÚAN Florenc8:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/26/2026 9:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 8:25:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 22h 30m
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FlixBus28h 40m01:20 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 1:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/27/2026 6:00:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 28h 40m
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FlixBus25h 0m05:45 PMPrague AirportPrague Airport - T1/26:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 6:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 25h 0m
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FlixBus27h 0m06:20 AMPragueČerný Most9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/26/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 9:20:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 0m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc4:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/26/2026 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 4:00:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 28h 15m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Wizz Air1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/27/2026 11:20:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/27/2026 11:20:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 55m
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LC Perú23h 10m010:35 PMPrague AirportPrague Airport - T1/29:45 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 10:35:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/28/2026 9:45:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 23h 10m
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Skyscanner1h 50m07:50 PMPrague AirportPrague Airport - T1/29:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 7:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/27/2026 9:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 50m
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Buzz14h 25m06:30 AMPrague AirportPrague Airport - T1/28:55 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 6:30:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/27/2026 8:55:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 14h 25m
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Ryanair1h 50m07:50 PMPrague AirportPrague Airport - T1/29:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 7:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/27/2026 9:40:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 1h 50m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc5:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/27/2026 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/29/2026 5:00:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 28h 15m
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FlixBus23h 50m06:55 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 3/27/2026 6:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 6:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 23h 50m
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FlixBus25h 35m05:10 PMPragueRoztyly6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 3/27/2026 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 6:45:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 25h 35m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/27/2026 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 11:00:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 20h 30m
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FlixBus27h 0m06:20 AMPragueČerný Most9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/27/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 9:20:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 27h 0m
Cheapest Flights Friday
Cheapest Buses Friday
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FlixBus27h 0m06:20 AMPragueČerný Most10:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/28/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/29/2026 10:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 27h 0m
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FlixBus26h 35m09:40 AMPragueNa Knížecí Station1:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/28/2026 9:40:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 3/29/2026 1:15:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 26h 35m
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FlixBus30h 20m010:45 PMPrague AirportPrague Airport - T1/26:05 AMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/28/2026 10:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/30/2026 6:05:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 30h 20m
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FlixBus22h 15m06:50 PMPrague AirportPrague Airport - T1/26:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/28/2026 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/29/2026 6:05:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 22h 15m
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FlixBus22h 55m06:50 PMPrague AirportPrague Airport - T1/26:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/28/2026 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/29/2026 6:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 22h 55m
Cheapest Buses Saturday
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LC Perú27h 5m06:05 PMPrague AirportPrague Airport - T1/29:10 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 6:05:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/30/2026 9:10:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 27h 5m
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LC Perú2h 0m09:25 AMPrague AirportPrague Airport - T1/211:25 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/29/2026 11:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 2h 0m
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Wizz Air2h 0m09:25 AMPrague AirportPrague Airport - T1/211:25 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/29/2026 11:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 2h 0m
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Skyscanner1h 50m01:50 PMPrague AirportPrague Airport - T1/23:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 1:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/29/2026 3:40:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 50m
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Buzz13h 55m07:10 AMPrague AirportPrague Airport - T1/29:05 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 7:10:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/29/2026 9:05:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 13h 55m
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Ryanair1h 50m01:50 PMPrague AirportPrague Airport - T1/23:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 1:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/29/2026 3:40:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 50m
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FlixBus27h 0m06:20 AMPragueČerný Most9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/29/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/30/2026 9:20:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 27h 0m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/30/2026 6:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 10m
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FlixBus20h 35m09:25 PMPragueÚAN Florenc6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/29/2026 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/30/2026 6:00:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 20h 35m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/30/2026 5:25:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 22h 35m
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FlixBus19h 15m02:15 PMPragueWilsonova Bus Station9:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/29/2026 2:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/30/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 15m
Cheapest Flights Sunday
Cheapest Buses Sunday
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FlixBus25h 35m05:10 PMPragueRoztyly6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 3/30/2026 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 6:45:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 25h 35m
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FlixBus22h 40m07:30 AMPragueWilsonova Bus Station6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/30/2026 7:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 6:10:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 22h 40m
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FlixBus22h 30m09:55 PMPragueÚAN Florenc8:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/30/2026 9:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 8:25:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 22h 30m
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FlixBus23h 20m07:25 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 3/30/2026 7:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 6:45:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 23h 20m
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FlixBus20h 35m09:25 PMPragueÚAN Florenc6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/30/2026 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/31/2026 6:00:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 35m
Cheapest Buses Monday
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FlixBus24h 15m09:05 AMPragueWilsonova Bus Station9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/31/2026 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/1/2026 9:20:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 24h 15m
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FlixBus24h 30m08:50 AMPragueÚAN Florenc9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/31/2026 8:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/1/2026 9:20:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 24h 30m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/31/2026 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 11:00:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 30m
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FlixBus27h 0m03:00 PMPragueČerný Most6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/31/2026 3:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 4/1/2026 6:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 27h 0m
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FlixBus26h 30m03:30 PMPragueRoztyly6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 3/31/2026 3:30:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 4/1/2026 6:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 26h 30m
Cheapest Buses Tuesday
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Skyscanner1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 10:05:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 10:05:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m07:20 PMPrague AirportPrague Airport - T1/29:10 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 7:20:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 9:10:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 1h 50m
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Buzz10h 50m011:00 AMPrague AirportPrague Airport - T1/29:50 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 11:00:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 9:50:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 10h 50m
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LC Perú21h 55m010:40 PMPrague AirportPrague Airport - T1/28:35 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 10:40:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/2/2026 8:35:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 21h 55m
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FlixBus23h 50m06:20 AMPragueČerný Most6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 4/1/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 6:10:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 23h 50m
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FlixBus23h 10m07:00 AMPragueÚAN Florenc6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/1/2026 7:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 6:10:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 23h 10m
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FlixBus22h 40m06:45 PMPragueRoztyly5:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 4/1/2026 6:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 5:25:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 22h 40m
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FlixBus24h 15m09:05 AMPragueWilsonova Bus Station9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 4/1/2026 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 9:20:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 24h 15m
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FlixBus24h 30m08:50 AMPragueÚAN Florenc9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/1/2026 8:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 9:20:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 24h 30m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
What are the fastest trips from Prague to Rome?
You can get to Rome from Prague in just 1h 50m with a Flight from Ryanair. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Ryanair1h 50m07:10 PMPrague AirportPrague Airport - T1/29:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 7:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/26/2026 9:00:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m07:10 PMPrague AirportPrague Airport - T1/29:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 7:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/26/2026 9:00:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:10 PMPrague AirportPrague Airport - T1/211:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 9:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/26/2026 11:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 55m
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport - T1/21:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/26/2026 1:15:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 55m
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Buzz4h 50m04:05 PMPrague AirportPrague Airport - T1/28:55 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 4:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/26/2026 8:55:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 4h 50m
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EasyJet Airline6h 5m09:00 AMPrague AirportPrague Airport - T1/23:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 9:00:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/26/2026 3:05:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 6h 5m
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FlixBus22h 30m09:55 PMPragueÚAN Florenc8:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/26/2026 9:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 8:25:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 22h 30m
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FlixBus25h 0m05:45 PMPrague AirportPrague Airport - T1/26:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 6:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 25h 0m
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FlixBus27h 0m06:20 AMPragueČerný Most9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/26/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 9:20:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 0m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc4:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/26/2026 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 4:00:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 28h 15m
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FlixBus28h 40m01:20 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/26/2026 1:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/27/2026 6:00:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 28h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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Skyscanner1h 50m07:50 PMPrague AirportPrague Airport - T1/29:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 7:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/27/2026 9:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m07:50 PMPrague AirportPrague Airport - T1/29:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 7:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/27/2026 9:40:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 1h 50m
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Wizz Air1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/27/2026 11:20:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/27/2026 11:20:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 55m
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Volotea4h 15m08:20 AMPrague AirportPrague Airport - T1/212:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 8:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/27/2026 12:35:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 4h 15m
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TAROM5h 55m09:30 AMPrague AirportPrague Airport - T1/23:25 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from TAROM goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/27/2026 9:30:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/27/2026 3:25:00 PM. 50 Economy ticket for $202 per person are available. Travel duration is 5h 55m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/27/2026 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/27/2026 11:00:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 20h 30m
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FlixBus23h 50m06:55 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 3/27/2026 6:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 6:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 23h 50m
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FlixBus25h 35m05:10 PMPragueRoztyly6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 3/27/2026 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 6:45:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 25h 35m
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FlixBus27h 0m06:20 AMPragueČerný Most9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/27/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/28/2026 9:20:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 27h 0m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc5:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/27/2026 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/29/2026 5:00:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 28h 15m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus22h 15m06:50 PMPrague AirportPrague Airport - T1/26:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/28/2026 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/29/2026 6:05:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 22h 15m
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FlixBus22h 55m06:50 PMPrague AirportPrague Airport - T1/26:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/28/2026 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/29/2026 6:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 22h 55m
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FlixBus26h 35m09:40 AMPragueNa Knížecí Station1:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 3/28/2026 9:40:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 3/29/2026 1:15:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 26h 35m
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FlixBus27h 0m06:20 AMPragueČerný Most10:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/28/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/29/2026 10:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 27h 0m
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FlixBus30h 20m010:45 PMPrague AirportPrague Airport - T1/26:05 AMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/28/2026 10:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/30/2026 6:05:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 30h 20m
Fastest Buses Saturday
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Skyscanner1h 50m01:50 PMPrague AirportPrague Airport - T1/23:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 1:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/29/2026 3:40:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m01:50 PMPrague AirportPrague Airport - T1/23:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 1:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 3/29/2026 3:40:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 50m
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport1:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 3/29/2026 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/29/2026 1:15:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 1h 55m
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LC Perú2h 0m09:25 AMPrague AirportPrague Airport - T1/211:25 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/29/2026 11:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 2h 0m
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Wizz Air2h 0m09:25 AMPrague AirportPrague Airport - T1/211:25 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/29/2026 11:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 2h 0m
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Brussels Airlines12h 5m09:15 PMPrague AirportPrague Airport - T1/29:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 9:15:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/30/2026 9:20:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 12h 5m
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FlixBus19h 15m02:15 PMPragueWilsonova Bus Station9:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/29/2026 2:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/30/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 15m
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FlixBus20h 35m09:25 PMPragueÚAN Florenc6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/29/2026 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/30/2026 6:00:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 20h 35m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/30/2026 5:25:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 3/29/2026 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/30/2026 6:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 10m
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FlixBus27h 0m06:20 AMPragueČerný Most9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/29/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/30/2026 9:20:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 27h 0m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus20h 35m09:25 PMPragueÚAN Florenc6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/30/2026 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/31/2026 6:00:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 35m
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FlixBus22h 30m09:55 PMPragueÚAN Florenc8:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/30/2026 9:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 8:25:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 22h 30m
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FlixBus22h 40m07:30 AMPragueWilsonova Bus Station6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/30/2026 7:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 6:10:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 22h 40m
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FlixBus23h 20m07:25 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 3/30/2026 7:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 6:45:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 23h 20m
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FlixBus25h 35m05:10 PMPragueRoztyly6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 3/30/2026 5:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 6:45:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 25h 35m
Fastest Buses Monday
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/31/2026 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/31/2026 11:00:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 30m
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FlixBus24h 15m09:05 AMPragueWilsonova Bus Station9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 3/31/2026 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/1/2026 9:20:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 24h 15m
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FlixBus24h 30m08:50 AMPragueÚAN Florenc9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 3/31/2026 8:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/1/2026 9:20:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 24h 30m
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FlixBus26h 30m03:30 PMPragueRoztyly6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 3/31/2026 3:30:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 4/1/2026 6:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 26h 30m
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FlixBus27h 0m03:00 PMPragueČerný Most6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 3/31/2026 3:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 4/1/2026 6:00:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 27h 0m
Fastest Buses Tuesday
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Skyscanner1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 10:05:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 10:05:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m07:20 PMPrague AirportPrague Airport - T1/29:10 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 7:20:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 9:10:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 1h 50m
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Buzz10h 50m011:00 AMPrague AirportPrague Airport - T1/29:50 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 11:00:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/1/2026 9:50:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 10h 50m
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LC Perú21h 55m010:40 PMPrague AirportPrague Airport - T1/28:35 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 4/1/2026 10:40:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 4/2/2026 8:35:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 21h 55m
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FlixBus22h 40m06:45 PMPragueRoztyly5:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 4/1/2026 6:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 5:25:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 22h 40m
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FlixBus23h 10m07:00 AMPragueÚAN Florenc6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/1/2026 7:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 6:10:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 23h 10m
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FlixBus23h 50m06:20 AMPragueČerný Most6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 4/1/2026 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 6:10:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 23h 50m
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FlixBus24h 15m09:05 AMPragueWilsonova Bus Station9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 4/1/2026 9:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 9:20:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 24h 15m
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FlixBus24h 30m08:50 AMPragueÚAN Florenc9:20 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 4/1/2026 8:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 4/2/2026 9:20:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 24h 30m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Prague to Rome
What are the most popular stations in Prague and Rome?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Prague? With 10 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Rome, you can pay as low as $49 with a Flight from LC Perú.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Rome in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Rome are FlixBus, LC Perú and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Settebagni, and look at flights from Prague Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Rome?
The most popular companies between Prague and Rome, are FlixBus, LC Perú and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: LC Perú, Skyscanner, Ryanair and 10 more.
All you need to know when you travel from Prague to Rome
Check all information on comfort and services on all modes of transports from Prague to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Rome
How can I reach Rome from Prague?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to Rome from Prague.
How far is Rome from Prague?
The distance between Prague and Rome is 572.5 miles.
What is the most ecofriendly mode of transport between Prague and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Prague to Rome?
You can get to Rome with just $49 by taking a Flight from LC Perú.
What is the fastest way to get from Prague to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 50m with a Flight from Ryanair.
More routes to Prague and to Rome
Looking for more options? Here you can see the most popular routes to Prague and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bratislava to Prague
- Brno to Prague
- Budapest to Prague
- Cologne/Bonn Airport to Prague
- Dortmund to Prague
- Dresden to Prague
- Frankfurt am Main Airport to Prague
- Frankfurt am Main to Prague
- Hamburg to Prague
- Karlovy Vary to Prague
- Krakow to Prague
- Leipzig to Prague
- London to Prague
- Lyon to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Rotterdam to Prague
- Salzburg to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Rome
- Ascoli Piceno to Rome
- Barcellona Pozzo di Gotto to Rome
- Bologna to Rome
- Catania to Rome
- Florence to Rome
- Francavilla Fontana to Rome
- Frascineto to Rome
- L'Aquila to Rome
- Matera to Rome
- Milan to Rome
- Mormanno to Rome
- Naples to Rome
- Palermo to Rome
- Porto D'Ascoli to Rome
- Porto San Giorgio to Rome
- Reggio Calabria to Rome
- Rome Ciampino Airport to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Taranto to Rome
- Teramo to Rome
- Villa San Giovanni to Rome
