What is the best way to travel from Prague to Rome?
Looking for a trip? Compare all the available Buses and Flights for the journey to Rome from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Prague?
You can get to Rome with just $87 by taking a Flight from LC Perú, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/17/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 2:05:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/17/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 2:05:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 45m
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FlixBus30h 45m011:20 AMPrague AirportPrague Airport - T1/26:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/17/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/18/2025 6:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 30h 45m
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FlixBus23h 50m09:40 AMPragueNa Knížecí Station9:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/17/2025 9:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 9:30:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 50m
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FlixBus24h 45m05:20 PMPragueÚAN Florenc6:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/17/2025 5:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/18/2025 6:05:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 45m
Cheapest Buses Wednesday
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 11:20:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 1h 55m
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Buzz7h 50m02:00 PMPrague AirportPrague Airport - T1/29:50 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 2:00:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 9:50:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 7h 50m
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Buzz6h 45m02:00 PMPrague AirportPrague Airport - T1/28:45 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 2:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 8:45:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 6h 45m
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Skyscanner1h 50m07:10 PMPrague AirportPrague Airport - T1/29:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 7:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 9:00:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m08:30 AMPrague AirportPrague Airport - T1/210:20 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 8:30:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 10:20:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 1h 50m
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EasyJet Airline5h 0m04:10 PMPrague AirportPrague Airport - T1/29:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 4:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 5h 0m
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FlixBus22h 10m011:20 AMPrague AirportPrague Airport - T1/29:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 11:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 9:30:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 22h 10m
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FlixBus22h 15m08:50 AMPrague AirportPrague Airport - T1/27:05 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 8:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 7:05:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 22h 15m
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FlixBus24h 15m010:45 PMPrague AirportPrague Airport - T1/211:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 10:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 11:00:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 24h 15m
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FlixBus30h 40m011:20 AMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/19/2025 6:00:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 30h 40m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/18/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 30m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/19/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/20/2025 6:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 10m
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FlixBus23h 50m06:20 AMPragueČerný Most6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/19/2025 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 6:10:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 23h 50m
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FlixBus23h 10m07:00 AMPragueÚAN Florenc6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/19/2025 7:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 6:10:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 23h 10m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc4:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/19/2025 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 4:00:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 28h 15m
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FlixBus23h 50m06:55 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/19/2025 6:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 6:45:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 23h 50m
Cheapest Buses Friday
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Skyscanner1h 50m07:30 PMPrague AirportPrague Airport - T1/29:20 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 7:30:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 9:20:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 10:05:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m02:25 PMPrague AirportPrague Airport - T1/24:15 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 2:25:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 4:15:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 1h 50m
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Buzz11h 55m012:20 PMPrague AirportPrague Airport - T1/212:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 12:20:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/21/2025 12:15:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 11h 55m
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Air Malta11h 5m08:40 PMPrague AirportPrague Airport - T1/27:45 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 8:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/21/2025 7:45:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 11h 5m
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Skyscanner4h 25m06:10 PMPrague AirportPrague Airport - T1/210:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 6:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 10:35:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 4h 25m
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FlixBus23h 20m07:25 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/20/2025 7:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 6:45:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 23h 20m
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FlixBus23h 20m010:20 PMPragueRoztyly9:40 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/20/2025 10:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 9:40:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 20m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc4:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/20/2025 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 4:00:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 28h 15m
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FlixBus20h 35m09:25 PMPragueÚAN Florenc6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/20/2025 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 6:00:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 6:00:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 23h 10m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/21/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/21/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 45m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/21/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/22/2025 6:00:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 23h 10m
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FlixBus19h 35m05:45 PMPragueNa Knížecí Station1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/21/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 1:20:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 19h 35m
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FlixBus24h 25m012:55 PMPragueZličín1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/21/2025 12:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 1:20:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 24h 25m
Cheapest Buses Sunday
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Skyscanner1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/22/2025 10:05:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 50m
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Volotea10h 15m08:35 AMPrague AirportPrague Airport - T1/26:50 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 8:35:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/22/2025 6:50:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 10h 15m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/22/2025 11:20:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 1h 55m
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Skyscanner1h 50m01:55 PMPrague AirportPrague Airport - T1/23:45 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 1:55:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/22/2025 3:45:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 1h 50m
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Buzz1h 50m05:50 PMPrague AirportPrague Airport - T1/27:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 5:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/22/2025 7:40:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 1h 50m
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport - T1/21:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/22/2025 1:15:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 1h 55m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 6:00:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 23h 10m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/22/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 11:00:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 20h 30m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 5:25:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 22h 35m
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FlixBus21h 20m05:45 PMPragueNa Knížecí Station3:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/22/2025 5:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 3:05:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 21h 20m
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FlixBus26h 15m012:50 PMPragueHradčanská3:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 12/22/2025 12:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 3:05:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 26h 15m
Cheapest Flights Monday
Cheapest Buses Monday
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Skyscanner1h 50m08:30 AMPrague AirportPrague Airport - T1/210:20 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 8:30:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/23/2025 10:20:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 50m
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Air Malta11h 5m08:40 PMPrague AirportPrague Airport - T1/27:45 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 8:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/24/2025 7:45:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 11h 5m
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Buzz12h 5m09:35 AMPrague AirportPrague Airport - T1/29:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:35:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/23/2025 9:40:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 12h 5m
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Buzz14h 0m05:55 AMPrague AirportPrague Airport - T1/27:55 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 5:55:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/23/2025 7:55:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 14h 0m
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Buzz10h 10m09:50 PMPrague AirportPrague Airport - T1/28:00 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:50:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/24/2025 8:00:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 10h 10m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/23/2025 11:20:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 1h 55m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 5:25:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/24/2025 6:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 23h 10m
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FlixBus23h 10m011:50 PMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/23/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 11:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 23h 10m
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FlixBus23h 25m011:35 PMPragueÚAN Florenc11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/23/2025 11:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 11:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 23h 25m
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FlixBus23h 20m010:20 PMPragueRoztyly9:40 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/23/2025 10:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/24/2025 9:40:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 20m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
What are the fastest trips from Prague to Rome?
You can get to Rome from Prague in just 1h 50m with a Flight from Skyscanner. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/17/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 2:05:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/17/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 2:05:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 45m
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FlixBus23h 50m09:40 AMPragueNa Knížecí Station9:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/17/2025 9:40:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 9:30:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 50m
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FlixBus24h 45m05:20 PMPragueÚAN Florenc6:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/17/2025 5:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/18/2025 6:05:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 45m
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FlixBus30h 45m011:20 AMPrague AirportPrague Airport - T1/26:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/17/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/18/2025 6:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 30h 45m
Fastest Buses Wednesday
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Skyscanner1h 50m07:10 PMPrague AirportPrague Airport - T1/29:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 7:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 9:00:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m08:30 AMPrague AirportPrague Airport - T1/210:20 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 8:30:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 10:20:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 11:20:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 1h 55m
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport - T1/21:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 1:15:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 1h 55m
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Buzz4h 50m05:55 AMPrague AirportPrague Airport - T1/210:45 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 5:55:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 10:45:00 AM. 50 Economy ticket for $199 per person are available. Travel duration is 4h 50m
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EasyJet Airline5h 0m04:10 PMPrague AirportPrague Airport - T1/29:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 4:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 5h 0m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/18/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 30m
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FlixBus22h 10m011:20 AMPrague AirportPrague Airport - T1/29:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 11:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 9:30:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 22h 10m
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FlixBus22h 15m08:50 AMPrague AirportPrague Airport - T1/27:05 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 8:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 7:05:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 22h 15m
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FlixBus24h 15m010:45 PMPrague AirportPrague Airport - T1/211:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 10:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 11:00:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 24h 15m
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FlixBus30h 40m011:20 AMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/18/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/19/2025 6:00:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 30h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/19/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/20/2025 6:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 10m
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FlixBus23h 10m07:00 AMPragueÚAN Florenc6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/19/2025 7:00:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 6:10:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 23h 10m
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FlixBus23h 50m06:20 AMPragueČerný Most6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 12/19/2025 6:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 6:10:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 23h 50m
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FlixBus23h 50m06:55 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/19/2025 6:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 6:45:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 23h 50m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc4:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/19/2025 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 4:00:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 28h 15m
Fastest Buses Friday
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Skyscanner1h 50m07:30 PMPrague AirportPrague Airport - T1/29:20 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 7:30:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 9:20:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 10:05:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m02:25 PMPrague AirportPrague Airport - T1/24:15 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 2:25:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 4:15:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 11:20:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 1h 55m
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Skyscanner4h 25m06:10 PMPrague AirportPrague Airport - T1/210:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 6:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 10:35:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 4h 25m
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Air Malta11h 5m08:40 PMPrague AirportPrague Airport - T1/27:45 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 8:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/21/2025 7:45:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 11h 5m
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FlixBus20h 35m09:25 PMPragueÚAN Florenc6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/20/2025 9:25:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 6:00:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/20/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 6:00:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 23h 10m
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FlixBus23h 20m07:25 PMPragueZličín6:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/20/2025 7:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 6:45:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 23h 20m
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FlixBus23h 20m010:20 PMPragueRoztyly9:40 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/20/2025 10:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 9:40:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 20m
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FlixBus28h 15m011:45 PMPragueÚAN Florenc4:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/20/2025 11:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 4:00:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 28h 15m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus19h 35m05:45 PMPragueNa Knížecí Station1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/21/2025 5:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 1:20:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 19h 35m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/21/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/21/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 45m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/21/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/22/2025 6:00:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 23h 10m
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FlixBus24h 25m012:55 PMPragueZličín1:20 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 12/21/2025 12:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 1:20:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 24h 25m
Fastest Buses Sunday
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Skyscanner1h 50m08:15 AMPrague AirportPrague Airport - T1/210:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 8:15:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/22/2025 10:05:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m01:55 PMPrague AirportPrague Airport - T1/23:45 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 1:55:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/22/2025 3:45:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 1h 50m
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Buzz1h 50m05:50 PMPrague AirportPrague Airport - T1/27:40 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 5:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/22/2025 7:40:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/22/2025 11:20:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 1h 55m
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport - T1/21:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/22/2025 1:15:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 1h 55m
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Buzz4h 50m03:40 PMPrague AirportPrague Airport - T1/28:30 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 3:40:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/22/2025 8:30:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 4h 50m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/22/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 11:00:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 20h 30m
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FlixBus21h 20m05:45 PMPragueNa Knížecí Station3:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/22/2025 5:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 3:05:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 21h 20m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 5:25:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/22/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 6:00:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 23h 10m
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FlixBus26h 15m012:50 PMPragueHradčanská3:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 12/22/2025 12:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 3:05:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 26h 15m
Fastest Flights Monday
Fastest Buses Monday
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Skyscanner1h 50m08:30 AMPrague AirportPrague Airport - T1/210:20 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 8:30:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/23/2025 10:20:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m02:35 PMPrague AirportPrague Airport - T1/24:25 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 2:35:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/23/2025 4:25:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/23/2025 11:20:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 1h 55m
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Buzz10h 10m09:50 PMPrague AirportPrague Airport - T1/28:00 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:50:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/24/2025 8:00:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 10h 10m
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Buzz10h 15m09:50 PMPrague AirportPrague Airport - T1/28:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/24/2025 8:05:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 10h 15m
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Air Malta11h 5m08:40 PMPrague AirportPrague Airport - T1/27:45 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 8:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/24/2025 7:45:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 11h 5m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 5:25:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/24/2025 6:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 23h 10m
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FlixBus23h 10m011:50 PMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/23/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 11:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 23h 10m
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FlixBus23h 20m010:20 PMPragueRoztyly9:40 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 12/23/2025 10:20:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/24/2025 9:40:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 20m
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FlixBus23h 25m011:35 PMPragueÚAN Florenc11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/23/2025 11:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 11:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 23h 25m
Fastest Flights Tuesday
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from Prague to Rome
What are the most popular stations in Prague and Rome?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Prague? With 10 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Rome, you can pay as low as $87 with a Flight from LC Perú.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Rome in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Rome are FlixBus, Buzz and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Settebagni, and look at flights from Prague Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Rome?
The most popular companies between Prague and Rome, are FlixBus, Buzz and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Buzz, Skyscanner, LC Perú and 8 more.
All you need to know when you travel from Prague to Rome
Check all information on comfort and services on all modes of transports from Prague to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Rome
How can I reach Rome from Prague?
Every day, there are on average 10 connections between Bus and Flight, with which you can get to Rome from Prague.
How far is Rome from Prague?
The distance between Prague and Rome is 572.5 miles.
What is the most ecofriendly mode of transport between Prague and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Prague to Rome?
You can get to Rome with just $87 by taking a Flight from LC Perú.
What is the fastest way to get from Prague to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 50m with a Flight from Skyscanner.
More routes to Prague and to Rome
Looking for more options? Here you can see the most popular routes to Prague and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bern to Prague
- Bratislava to Prague
- Brno to Prague
- Chemnitz to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- London to Prague
- Lyon to Prague
- Memmingen to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Regensburg to Prague
- Teplice to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Rome
- Avellino to Rome
- Benevento to Rome
- Brindisi to Rome
- Caserta to Rome
- Cassino to Rome
- Catania to Rome
- Civitanova to Rome
- Civitavecchia to Rome
- Cosenza to Rome
- Fasano to Rome
- Florence to Rome
- Frascineto to Rome
- Grosseto to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lanciano to Rome
- Milan to Rome
- Naples to Rome
- Porto D'Ascoli to Rome
- Porto San Giorgio to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Todi to Rome

