What is the best way to travel from Prague to Rome?
Looking for a trip? Compare all the available Buses and Flights for the journey to Rome from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Prague?
You can get to Rome with just $66 by taking a Flight from Smartwings, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/24/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 2:05:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 20h 45m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/24/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 2:05:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 20h 30m
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FlixBus22h 10m011:20 AMPrague AirportPrague Airport - T1/29:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/24/2025 11:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 9:30:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 10m
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FlixBus24h 15m010:45 PMPrague AirportPrague Airport - T1/211:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/24/2025 10:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 11:00:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 24h 15m
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FlixBus28h 15m06:45 PMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/24/2025 6:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 11:00:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 28h 15m
Cheapest Buses Wednesday
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport - T1/21:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/25/2025 1:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/25/2025 11:20:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 1h 55m
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Air Bagan8h 10m05:05 PMPrague AirportPrague Airport - T1/21:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 5:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 1:15:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 8h 10m
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Wizz Air8h 10m05:05 PMPrague AirportPrague Airport1:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 12/25/2025 5:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 1:15:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 8h 10m
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Iberia8h 35m03:40 PMPrague AirportPrague Airport - T1/212:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 3:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 12:15:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 8h 35m
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Air Bagan21h 50m05:05 PMPrague AirportPrague Airport - T1/22:55 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 5:05:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/26/2025 2:55:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 21h 50m
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RegioJet20h 15m06:30 PMPragueÚAN Florenc2:45 PMRomeTiburtina Bus Station0EconomyA Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 12/25/2025 6:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 2:45:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 15m
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FlixBus30h 40m011:20 AMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/26/2025 6:00:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 30h 40m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/25/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/25/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 45m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/27/2025 6:00:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 23h 10m
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FlixBus27h 45m011:20 AMPrague AirportPrague Airport - T1/23:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/27/2025 3:05:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 27h 45m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/26/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 2:05:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/26/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 2:05:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 20h 45m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 5:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 22h 35m
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport1:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 1:15:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 1h 55m
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Air Serbia11h 45m08:30 PMPrague AirportPrague Airport8:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 8:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/27/2025 8:15:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 11h 45m
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Volotea10h 55m08:35 AMPrague AirportPrague Airport7:30 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 8:35:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 7:30:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 10h 55m
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Brussels Airlines8h 35m011:40 AMPrague AirportPrague Airport8:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 11:40:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 8:15:00 PM. 50 Economy ticket for $201 per person are available. Travel duration is 8h 35m
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EasyJet Airline10h 50m09:05 AMPrague AirportPrague Airport7:55 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 9:05:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 7:55:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 10h 50m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus27h 45m011:20 AMPrague AirportPrague Airport - T1/23:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/28/2025 3:05:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 27h 45m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/28/2025 6:00:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 23h 10m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/27/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/28/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/27/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/28/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 45m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/28/2025 5:25:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 22h 35m
Cheapest Buses Saturday
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Buzz1h 50m06:20 AMPrague AirportPrague Airport - T1/28:10 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:20:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/28/2025 8:10:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/28/2025 11:20:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 1h 55m
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Air Serbia11h 45m08:30 PMPrague AirportPrague Airport - T1/28:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 8:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/29/2025 8:15:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 11h 45m
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Skyscanner1h 50m06:40 PMPrague AirportPrague Airport - T1/28:30 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:40:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/28/2025 8:30:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 50m
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EasyJet Airline28h 30m08:45 PMPrague AirportPrague Airport1:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 12/28/2025 8:45:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/30/2025 1:15:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 28h 30m
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Jet2.com16h 55m07:40 PMPrague AirportPrague Airport - T1/212:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 7:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/29/2025 12:35:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 16h 55m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 5:25:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/29/2025 6:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 23h 10m
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RegioJet20h 15m06:30 PMPragueÚAN Florenc2:45 PMRomeTiburtina Bus Station0EconomyA Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 12/28/2025 6:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 2:45:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 15m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/28/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 2:05:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 20h 30m
Cheapest Flights Sunday
Cheapest Buses Sunday
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/29/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/30/2025 6:00:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 23h 10m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/29/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 5:25:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 22h 35m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/29/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/29/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 45m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/29/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 11:00:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 20h 30m
Cheapest Buses Monday
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/31/2025 6:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 10m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/30/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 11:00:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 30m
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FlixBus24h 45m010:15 PMPragueNa Knížecí Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/30/2025 10:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/31/2025 11:00:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 24h 45m
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FlixBus23h 10m011:50 PMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/30/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/31/2025 11:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 10m
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FlixBus23h 25m011:35 PMPragueÚAN Florenc11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/30/2025 11:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/31/2025 11:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 25m
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Jet2.com21h 5m04:00 PMPrague AirportPrague Airport - T1/21:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 4:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/31/2025 1:05:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 21h 5m
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Ryanair8h 55m011:35 AMPrague AirportPrague Airport - T1/28:30 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 11:35:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/30/2025 8:30:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 8h 55m
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Jet2.com7h 45m012:45 PMPrague AirportPrague Airport - T1/28:30 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 12:45:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/30/2025 8:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 7h 45m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/30/2025 11:20:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 1h 55m
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Smartwings28h 35m06:40 AMPrague AirportPrague Airport11:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 12/30/2025 6:40:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/31/2025 11:15:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 28h 35m
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Buzz10h 25m09:15 PMPrague AirportPrague Airport - T1/27:40 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 9:15:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/31/2025 7:40:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 10h 25m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
What are the fastest trips from Prague to Rome?
You can get to Rome from Prague in just 1h 50m with a Flight from Buzz. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/24/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 2:05:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/24/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 2:05:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 20h 45m
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FlixBus22h 10m011:20 AMPrague AirportPrague Airport - T1/29:30 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/24/2025 11:20:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 9:30:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 10m
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FlixBus24h 15m010:45 PMPrague AirportPrague Airport - T1/211:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/24/2025 10:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 11:00:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 24h 15m
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FlixBus28h 15m06:45 PMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/24/2025 6:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 11:00:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 28h 15m
Fastest Buses Wednesday
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport - T1/21:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/25/2025 1:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/25/2025 11:20:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 1h 55m
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Air Bagan8h 10m05:05 PMPrague AirportPrague Airport - T1/21:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 5:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 1:15:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 8h 10m
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Wizz Air8h 10m05:05 PMPrague AirportPrague Airport1:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 12/25/2025 5:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 1:15:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 8h 10m
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Iberia8h 35m03:40 PMPrague AirportPrague Airport - T1/212:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 3:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 12:15:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 8h 35m
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Swiss International Air Lines15h 25m08:15 PMPrague AirportPrague Airport - T1/211:40 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Swiss International Air Lines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 8:15:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/26/2025 11:40:00 AM. 50 Economy ticket for $434 per person are available. Travel duration is 15h 25m
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RegioJet20h 15m06:30 PMPragueÚAN Florenc2:45 PMRomeTiburtina Bus Station0EconomyA Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 12/25/2025 6:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 2:45:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 15m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/25/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/25/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 2:05:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 20h 45m
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FlixBus30h 40m011:20 AMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/26/2025 6:00:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 30h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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Smartwings1h 55m011:20 AMPrague AirportPrague Airport1:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 11:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 1:15:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 1h 55m
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Brussels Airlines8h 35m011:40 AMPrague AirportPrague Airport8:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 11:40:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 8:15:00 PM. 50 Economy ticket for $201 per person are available. Travel duration is 8h 35m
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EasyJet Airline10h 50m09:05 AMPrague AirportPrague Airport7:55 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 9:05:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 7:55:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 10h 50m
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Volotea10h 55m08:35 AMPrague AirportPrague Airport7:30 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 8:35:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/26/2025 7:30:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 10h 55m
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Air Serbia11h 45m08:30 PMPrague AirportPrague Airport8:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 12/26/2025 8:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/27/2025 8:15:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 11h 45m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/26/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 2:05:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/26/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 2:05:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 20h 45m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 5:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/27/2025 6:00:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 23h 10m
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FlixBus27h 45m011:20 AMPrague AirportPrague Airport - T1/23:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/27/2025 3:05:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 27h 45m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/27/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/28/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/27/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/28/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 45m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/28/2025 5:25:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/28/2025 6:00:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 23h 10m
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FlixBus27h 45m011:20 AMPrague AirportPrague Airport - T1/23:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 11:20:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/28/2025 3:05:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 27h 45m
Fastest Buses Saturday
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Buzz1h 50m06:20 AMPrague AirportPrague Airport - T1/28:10 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:20:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/28/2025 8:10:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m06:40 PMPrague AirportPrague Airport - T1/28:30 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:40:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/28/2025 8:30:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/28/2025 11:20:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 1h 55m
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Air Serbia11h 45m08:30 PMPrague AirportPrague Airport - T1/28:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 8:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/29/2025 8:15:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 11h 45m
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Ryanair14h 45m09:50 PMPrague AirportPrague Airport - T1/212:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 9:50:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/29/2025 12:35:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 14h 45m
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Jet2.com16h 55m07:40 PMPrague AirportPrague Airport - T1/212:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 7:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/29/2025 12:35:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 16h 55m
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RegioJet20h 15m06:30 PMPragueÚAN Florenc2:45 PMRomeTiburtina Bus Station0EconomyA Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 12/28/2025 6:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 2:45:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 15m
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/28/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 2:05:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 20h 30m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 5:25:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/29/2025 6:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 23h 10m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus20h 30m05:35 PMPragueWilsonova Bus Station2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/29/2025 5:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 30m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/29/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 11:00:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m05:20 PMPragueÚAN Florenc2:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/29/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 2:05:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 20h 45m
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FlixBus22h 35m06:50 PMPrague AirportPrague Airport - T1/25:25 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/29/2025 6:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 5:25:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/29/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/30/2025 6:00:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 23h 10m
Fastest Buses Monday
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Skyscanner1h 50m08:30 AMPrague AirportPrague Airport - T1/210:20 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 8:30:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/30/2025 10:20:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m02:35 PMPrague AirportPrague Airport - T1/24:25 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 2:35:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/30/2025 4:25:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m09:25 AMPrague AirportPrague Airport - T1/211:20 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 9:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/30/2025 11:20:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 1h 55m
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Jet2.com7h 45m012:45 PMPrague AirportPrague Airport - T1/28:30 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 12:45:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/30/2025 8:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 7h 45m
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Ryanair8h 55m011:35 AMPrague AirportPrague Airport - T1/28:30 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 11:35:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/30/2025 8:30:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 8h 55m
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Buzz10h 25m09:15 PMPrague AirportPrague Airport - T1/27:40 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 9:15:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/31/2025 7:40:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 10h 25m
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FlixBus20h 30m02:30 AMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/30/2025 2:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/30/2025 11:00:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 30m
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FlixBus23h 10m06:50 PMPrague AirportPrague Airport - T1/26:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/30/2025 6:50:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/31/2025 6:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 10m
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FlixBus23h 10m011:50 PMPragueWilsonova Bus Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/30/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/31/2025 11:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 10m
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FlixBus23h 25m011:35 PMPragueÚAN Florenc11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/30/2025 11:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/31/2025 11:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 25m
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FlixBus24h 45m010:15 PMPragueNa Knížecí Station11:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/30/2025 10:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/31/2025 11:00:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 24h 45m
Fastest Flights Tuesday
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from Prague to Rome
What are the most popular stations in Prague and Rome?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Prague? With 9 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Rome, you can pay as low as $66 with a Flight from Smartwings.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Buzz: you will get to Rome in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Rome are FlixBus, Smartwings and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Settebagni, and look at flights from Prague Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Rome?
The most popular companies between Prague and Rome, are FlixBus, Smartwings and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Smartwings, Skyscanner, Jet2.com and 13 more.
All you need to know when you travel from Prague to Rome
Check all information on comfort and services on all modes of transports from Prague to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Rome
How can I reach Rome from Prague?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Rome from Prague.
How far is Rome from Prague?
The distance between Prague and Rome is 572.5 miles.
What is the most ecofriendly mode of transport between Prague and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Prague to Rome?
You can get to Rome with just $66 by taking a Flight from Smartwings.
What is the fastest way to get from Prague to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 50m with a Flight from Buzz.
More routes to Prague and to Rome
Looking for more options? Here you can see the most popular routes to Prague and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Brno to Prague
- Budapest to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Michalovce to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Pelhřimov to Prague
- Presov to Prague
- Třebíč to Prague
- Vienna to Prague
- Vilnius to Prague
- Zurich to Prague
- Trips to Rome
- Ascoli Piceno to Rome
- Caserta to Rome
- Catania to Rome
- Ciampino to Rome
- Ferrandina to Rome
- Frascineto to Rome
- L'Aquila to Rome
- London to Rome
- Matera to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Parma to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Porto San Giorgio to Rome
- Reggio Calabria to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Siena to Rome
- Turin to Rome
- Villa San Giovanni to Rome
