Bus Florence to Palermo - Compare all Companies

Compare all timetables for the bus from Florence to Palermo

Here is a selection of the cheapest bus trips from the schedule from Florence to Palermo from various bus operators like FlixBus for the next days.

today

$110

tomorrow

$97

Sunday

$65

Monday

$70

Tuesday

$87

Wednesday

Thursday

$129

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 5m	5:55 PM	Florence	Villa Costanza Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$110	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/12/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/13/2025 11:00:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 17h 5m
FlixBus	20h 30m	5:55 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$110	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/12/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/13/2025 2:25:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 20h 30m
FlixBus	16h 25m	10:00 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$110	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/12/2025 10:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/13/2025 2:25:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 16h 25m

Did you know that if you travel from Florence to Palermo via Rome, you can save more than $34? You can find the corresponding connections below.
- Bookaway
  
  17h 55m
  
  0
  
  8:30 PM
  
  Florence
  Villa Costanza Bus Station
  
  11:45 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Basic
  
  $10
  
  A Bus from Bookaway goes from Villa Costanza Bus Station, Florence (Italy) at 12/13/2025 8:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/13/2025 11:45:00 PM. 50 Basic ticket for $10 per person are available. Travel duration is 3h 15m
- FlixBus
  
  13h 10m
  
  0
  
  1:15 AM
  
  Rome
  Tiburtina Bus Station
  
  2:25 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  0
  
  Economy
  
  $66
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/14/2025 1:15:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/14/2025 2:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 10m
Travel time is 1h 30m longer, but you will save $34

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 30m	5:55 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$97	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/13/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/14/2025 2:25:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 20h 30m
FlixBus	16h 25m	10:00 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$101	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/13/2025 10:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/14/2025 2:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 16h 25m
FlixBus	17h 5m	5:55 PM	Florence	Villa Costanza Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$108	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/13/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/14/2025 11:00:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 17h 5m

Did you know that if you travel from Florence to Palermo via Rome, you can save more than $21? You can find the corresponding connections below.
- Bookaway
  
  17h 55m
  
  0
  
  8:30 PM
  
  Florence
  Villa Costanza Bus Station
  
  11:45 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Basic
  
  $10
  
  A Bus from Bookaway goes from Villa Costanza Bus Station, Florence (Italy) at 12/13/2025 8:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/13/2025 11:45:00 PM. 50 Basic ticket for $10 per person are available. Travel duration is 3h 15m
- FlixBus
  
  13h 10m
  
  0
  
  1:15 AM
  
  Rome
  Tiburtina Bus Station
  
  2:25 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  0
  
  Economy
  
  $66
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/14/2025 1:15:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/14/2025 2:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 10m
Travel time is 1h 30m longer, but you will save $21

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 5m	5:55 PM	Florence	Villa Costanza Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$65	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/14/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/15/2025 11:00:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 17h 5m
FlixBus	20h 30m	5:55 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$69	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/14/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/15/2025 2:25:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 20h 30m
FlixBus	16h 25m	10:00 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$82	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/14/2025 10:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/15/2025 2:25:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 16h 25m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 30m	5:55 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$70	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/15/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/16/2025 2:25:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 20h 30m
FlixBus	17h 5m	5:55 PM	Florence	Villa Costanza Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$73	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/15/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/16/2025 11:00:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 17h 5m
FlixBus	16h 25m	10:00 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$87	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/15/2025 10:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/16/2025 2:25:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 16h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 5m	5:55 PM	Florence	Villa Costanza Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$87	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/16/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/17/2025 11:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 5m
FlixBus	20h 30m	5:55 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$89	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/16/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/17/2025 2:25:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 20h 30m
FlixBus	16h 25m	10:00 PM	Florence	Villa Costanza Bus Station	2:25 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$93	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/16/2025 10:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/17/2025 2:25:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 25m

Did you know that if you travel from Florence to Palermo via Rome, you can save more than $11? You can find the corresponding connections below.
- Bookaway
  
  17h 55m
  
  0
  
  8:30 PM
  
  Florence
  Villa Costanza Bus Station
  
  11:45 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Basic
  
  $10
  
  A Bus from Bookaway goes from Villa Costanza Bus Station, Florence (Italy) at 12/13/2025 8:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/13/2025 11:45:00 PM. 50 Basic ticket for $10 per person are available. Travel duration is 3h 15m
- FlixBus
  
  13h 10m
  
  0
  
  1:15 AM
  
  Rome
  Tiburtina Bus Station
  
  2:25 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  0
  
  Economy
  
  $66
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/14/2025 1:15:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/14/2025 2:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 10m
Travel time is 1h 30m longer, but you will save $11

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	17h 5m	5:55 PM	Florence	Villa Costanza Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$129	A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 12/18/2025 5:55:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/19/2025 11:00:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 17h 5m

Did you know that if you travel from Florence to Palermo via Rome, you can save more than $67? You can find the corresponding connections below.
- Distribusion
  
  17h 30m
  
  0
  
  2:30 PM
  
  Florence
  Villa Costanza Bus Station
  
  5:45 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $14
  
  A Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 12/20/2025 2:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 5:45:00 PM. 50 Premium Economy ticket for $14 per person are available. Travel duration is 3h 15m
- Bookaway
  
  13h 15m
  
  0
  
  6:45 PM
  
  Rome
  Tiburtina Bus Station
  
  8:00 AM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  0
  
  Basic
  
  $48
  
  A Bus from Bookaway goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 6:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 12/21/2025 8:00:00 AM. 50 Basic ticket for $48 per person are available. Travel duration is 13h 15m
Travel time is 0h 25m longer, but you will save $67

Best Price Offer: The price for the cheapest bus from Florence to Palermo is $65 on 1/2/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Florence and Palermo

See here how frequent the connections between Florence and Palermo are, during different times and days of the week.

Sunday is the busiest day, with more than 3 daily buses from Florence to Palermo. Thursday has instead the fewest connections, with only 1 daily coaches between Florence and Palermo.

The busiest time of the day is the Afternoon, with 11 buses from Florence to Palermo, while Evening sees the fewest connections between Florence and Palermo, with 5 offers.

Facts about the bus from Florence to Palermo

Compare all providers like FlixBus that travel 2 times every day by bus from Florence to Palermo in one click! Book your bus ticket from Florence to Palermo starting from $65!

Cheapest Bus	$65
Fastest Bus	16h 25m
Earliest Bus	5:55 PM
Latest Bus	5:55 PM
Daily Bus Routes	2 Ø
Distance	406.1 miles
Bus Companies	FlixBus

Cheapest bus connections from Florence to Palermo

Every day, 2 buses from 1 bus companies leave Florence for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/12/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

Friday 12/12

$110

Saturday 12/13

$97

Sunday 12/14

$65

Monday 12/15

$70

Tuesday 12/16

$87

Wednesday 12/17

Thursday 12/18

$129

Friday 12/19

$128

Saturday 12/20

$175

Sunday 12/21

$160

Monday 12/22

$163

Tuesday 12/23

$185

Wednesday 12/24

$121

Thursday 12/25

Friday 12/26

Saturday 12/27

$81

Sunday 12/28

$77

Monday 12/29

$93

Tuesday 12/30

$95

Wednesday 12/31

$87

Thursday 01/01

Friday 01/02

$65

Saturday 01/03

The cheapest time to travel from Florence to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Florence to Palermo, for the next 30 days.

With a price starting from $41, Monday is the cheapest day for a bus from Florence to Palermo. Thursday instead is the most expensive day with prices starting from $128.

Afternoon is the cheapest day time for bus tickets from Florence to Palermo, with $65. Evening is the most expensive time of the day with prices starting from $82.

How to save money travelling from Florence to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence to Palermo are also emptier.

All bus stations and stops in Florence and Palermo

In the map below, you can see where to find all bus stations in Florence and Palermo.

Guidoni T2 Bus Station

Viale Alessandro Guidoni 211

Piazza della Stazione Bus Station

Piazza della Stazione

Piazzale Montelungo Bus Stop

Viale Filippo Strozzi - Piazzale Montelungo (Stazione Novella)

Villa Costanza Bus Station

A1 73B

Calenzano Testanera Bus Stop

Via Vittorio Emanuele 3

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Florence to Palermo? Compare all modes of transports from Florence to Palermo.

Service and Comfort on the bus from Florence to Palermo

Want to know which seat classes are available on the buses from Florence to Palermo? Or which bus companies serve the route Florence to Palermo? Below you will find answers to your questions.

FAQs about the Florence to Palermo bus

How much does a Florence Palermo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $65 and takes 17h 5m to reach Palermo. Compare offers to save money!

How much could I save by comparing buses from Florence to Palermo?

This route is offered by 1 companies with a range of ticket prices between $65 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Palermo.

On average, how many connections are available from Florence to Palermo each day?

Every day, the Florence to Palermo bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence to Palermo take?

The fastest bus from Florence to Palermo is offered by FlixBus and takes 16h 25m. Bus tickets for this connection cost $110. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence to Palermo?

The earliest bus arriving in Palermo from Florence starts at 5:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence to Palermo?

The latest bus trip departing from Florence for Palermo starts at 5:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence Palermo route?

When traveling by bus from Florence to Palermo, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence and Palermo?

You can check all the direct connections between Florence and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Florence to Palermo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence Palermo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence to Palermo on your planned travel date.

How does CheckMyBus find the best bus deals from Florence to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Florence and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Florence to Palermo?

Prices and availability for 2 trips between Florence and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Florence to Palermo

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Florence and to Palermo

Here’s an overview of the most popular bus routes to Florence and to Palermo. Simply click on the connection of your choice, and you will find all the details about your bus route!