What is the best way to travel from Mendoza to Santiago del Estero?
Looking for a trip? Compare all the available Buses and Flights for the journey to Santiago del Estero from Mendoza. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Santiago del Estero from Mendoza?
You can get to Santiago del Estero with just $72 by taking a Bus from San Juan Mar del Plata, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/4/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/5/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
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20 de Junio19h 20m08:30 PMMendozaBus Station3:50 PMSantiago del EsteroCentral Bus Station0First ClassA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/4/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/5/2025 3:50:00 PM. 50 First Class ticket for $104 per person are available. Travel duration is 19h 20m
Cheapest Buses Thursday
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/6/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
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Andesmar16h 5m09:30 PMMendozaBus Station1:35 PMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/6/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
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20 de Junio19h 20m08:30 PMMendozaBus Station3:50 PMSantiago del EsteroCentral Bus Station0First ClassA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/6/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 3:50:00 PM. 50 First Class ticket for $99 per person are available. Travel duration is 19h 20m
Cheapest Buses Saturday
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/7/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
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Andesmar16h 5m09:30 PMMendozaBus Station1:35 PMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/7/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
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20 de Junio19h 20m08:30 PMMendozaBus Station3:50 PMSantiago del EsteroCentral Bus Station0First ClassA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/7/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 3:50:00 PM. 50 First Class ticket for $99 per person are available. Travel duration is 19h 20m
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JetSMART Airlines Peru20h 25m010:20 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport6:45 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from JetSMART Airlines Peru goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 10:20:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/8/2025 6:45:00 PM. 50 Economy ticket for $279 per person are available. Travel duration is 20h 25m
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Aerolíneas Argentinas5h 20m07:30 AMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport12:50 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 7:30:00 AM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/7/2025 12:50:00 PM. 50 Economy ticket for $347 per person are available. Travel duration is 5h 20m
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Aerolíneas Argentinas7h 10m02:25 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport9:35 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 2:25:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/7/2025 9:35:00 PM. 50 Economy ticket for $491 per person are available. Travel duration is 7h 10m
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Flybondi5h 35m04:00 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport9:35 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 4:00:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/7/2025 9:35:00 PM. 50 Economy ticket for $532 per person are available. Travel duration is 5h 35m
Cheapest Buses Sunday
Cheapest Flights Sunday
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/8/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
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Andesmar16h 5m09:30 PMMendozaBus Station1:35 PMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/8/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
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Flybondi22h 25m08:55 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:20 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 8:55:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $322 per person are available. Travel duration is 22h 25m
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Flybondi26h 55m04:25 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:20 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 4:25:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $323 per person are available. Travel duration is 26h 55m
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Flybondi21h 20m010:00 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:20 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 10:00:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $325 per person are available. Travel duration is 21h 20m
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Aerolíneas Argentinas11h 15m07:30 AMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport6:45 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 7:30:00 AM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/8/2025 6:45:00 PM. 50 Economy ticket for $337 per person are available. Travel duration is 11h 15m
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Aerolíneas Argentinas5h 55m012:50 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport6:45 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 12:50:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/8/2025 6:45:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 5h 55m
Cheapest Buses Monday
Cheapest Flights Monday
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JetSMART Airlines Peru21h 50m010:40 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport8:30 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from JetSMART Airlines Peru goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 10:40:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/11/2025 8:30:00 PM. 50 Economy ticket for $276 per person are available. Travel duration is 21h 50m
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Aerolíneas Argentinas25h 25m07:05 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport8:30 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 7:05:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/11/2025 8:30:00 PM. 50 Economy ticket for $289 per person are available. Travel duration is 25h 25m
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Flybondi11h 10m07:55 AMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:05 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 7:55:00 AM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/10/2025 7:05:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 11h 10m
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Flybondi5h 40m01:25 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:05 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 1:25:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/10/2025 7:05:00 PM. 50 Economy ticket for $297 per person are available. Travel duration is 5h 40m
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Aerolíneas Argentinas5h 30m01:35 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:05 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 1:35:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/10/2025 7:05:00 PM. 50 Economy ticket for $342 per person are available. Travel duration is 5h 30m
Cheapest Flights Wednesday
What are the fastest trips from Mendoza to Santiago del Estero?
You can get to Santiago del Estero from Mendoza in just 5h 20m with a Flight from Aerolíneas Argentinas. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/4/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/5/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
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20 de Junio19h 20m08:30 PMMendozaBus Station3:50 PMSantiago del EsteroCentral Bus Station0First ClassA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/4/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/5/2025 3:50:00 PM. 50 First Class ticket for $104 per person are available. Travel duration is 19h 20m
Fastest Buses Thursday
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Andesmar16h 5m09:30 PMMendozaBus Station1:35 PMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/6/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/6/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
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20 de Junio19h 20m08:30 PMMendozaBus Station3:50 PMSantiago del EsteroCentral Bus Station0First ClassA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/6/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 3:50:00 PM. 50 First Class ticket for $99 per person are available. Travel duration is 19h 20m
Fastest Buses Saturday
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Aerolíneas Argentinas5h 20m07:30 AMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport12:50 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 7:30:00 AM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/7/2025 12:50:00 PM. 50 Economy ticket for $347 per person are available. Travel duration is 5h 20m
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Flybondi5h 35m04:00 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport9:35 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 4:00:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/7/2025 9:35:00 PM. 50 Economy ticket for $532 per person are available. Travel duration is 5h 35m
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Aerolíneas Argentinas7h 10m02:25 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport9:35 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 2:25:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/7/2025 9:35:00 PM. 50 Economy ticket for $491 per person are available. Travel duration is 7h 10m
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JetSMART Airlines Peru20h 25m010:20 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport6:45 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from JetSMART Airlines Peru goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/7/2025 10:20:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/8/2025 6:45:00 PM. 50 Economy ticket for $279 per person are available. Travel duration is 20h 25m
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Andesmar16h 5m09:30 PMMendozaBus Station1:35 PMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/7/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/7/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
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20 de Junio19h 20m08:30 PMMendozaBus Station3:50 PMSantiago del EsteroCentral Bus Station0First ClassA Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/7/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 3:50:00 PM. 50 First Class ticket for $99 per person are available. Travel duration is 19h 20m
Fastest Flights Sunday
Fastest Buses Sunday
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Aerolíneas Argentinas5h 55m012:50 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport6:45 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 12:50:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/8/2025 6:45:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 5h 55m
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Aerolíneas Argentinas11h 15m07:30 AMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport6:45 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 7:30:00 AM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/8/2025 6:45:00 PM. 50 Economy ticket for $337 per person are available. Travel duration is 11h 15m
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Flybondi21h 20m010:00 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:20 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 10:00:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $325 per person are available. Travel duration is 21h 20m
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Flybondi22h 25m08:55 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:20 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 8:55:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $322 per person are available. Travel duration is 22h 25m
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Flybondi26h 55m04:25 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:20 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/8/2025 4:25:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $323 per person are available. Travel duration is 26h 55m
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Andesmar16h 5m09:30 PMMendozaBus Station1:35 PMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/8/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
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San Juan Mar del Plata17h 10m010:50 AMMendozaBus Station4:00 AMSantiago del EsteroCentral Bus Station0Premium EconomyA Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/8/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
Fastest Flights Monday
Fastest Buses Monday
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Aerolíneas Argentinas5h 30m01:35 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:05 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 1:35:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/10/2025 7:05:00 PM. 50 Economy ticket for $342 per person are available. Travel duration is 5h 30m
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Flybondi5h 40m01:25 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:05 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 1:25:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/10/2025 7:05:00 PM. 50 Economy ticket for $297 per person are available. Travel duration is 5h 40m
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Flybondi11h 10m07:55 AMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport7:05 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Flybondi goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 7:55:00 AM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/10/2025 7:05:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 11h 10m
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JetSMART Airlines Peru21h 50m010:40 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport8:30 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from JetSMART Airlines Peru goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 10:40:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/11/2025 8:30:00 PM. 50 Economy ticket for $276 per person are available. Travel duration is 21h 50m
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Aerolíneas Argentinas25h 25m07:05 PMMendoza Governor Francisco Gabrielli AirportMendoza Governor Francisco Gabrielli Airport8:30 PMSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés AirportSantiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport0EconomyA Flight from Aerolíneas Argentinas goes from Mendoza Governor Francisco Gabrielli Airport, Mendoza Governor Francisco Gabrielli Airport (Argentina) at 12/10/2025 7:05:00 PM to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport (Argentina) arriving at 12/11/2025 8:30:00 PM. 50 Economy ticket for $289 per person are available. Travel duration is 25h 25m
Fastest Flights Wednesday
Here you will find all operators and timetables for a
Bus from Mendoza to Santiago del Estero
What are the most popular stations in Mendoza and Santiago del Estero?
In Mendoza, you will usually depart from Hotel Hyatt, Bus Station or Vizcacheras, while in Santiago del Estero you will be arriving at Central Bus Station, Bus Stop or Av. Libertad & Av. Aguirre, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Santiago del Estero from Mendoza? With 6 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mendoza and Santiago del Estero, you can pay as low as $72 with a Bus from San Juan Mar del Plata.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Aerolíneas Argentinas: you will get to Santiago del Estero in just 5h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mendoza and Santiago del Estero are San Juan Mar del Plata, Andesmar and Aerolíneas Argentinas, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mendoza and Santiago del Estero is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Godoy Cruz, MZ or to Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport, and look at flights from Mendoza Governor Francisco Gabrielli Airport, and landing at Santiago del Estero - Vicecomodoro Ángel de la Paz Aragonés Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mendoza to Santiago del Estero?
The most popular companies between Mendoza and Santiago del Estero, are San Juan Mar del Plata, Andesmar and Aerolíneas Argentinas. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: San Juan Mar del Plata, Andesmar and 20 de Junio
Airlines: Aerolíneas Argentinas, Flybondi and JetSMART Airlines Peru
All you need to know when you travel from Mendoza to Santiago del Estero
Check all information on comfort and services on all modes of transports from Mendoza to Santiago del Estero. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mendoza to Santiago del Estero
How can I reach Santiago del Estero from Mendoza?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to Santiago del Estero from Mendoza.
How far is Santiago del Estero from Mendoza?
The distance between Mendoza and Santiago del Estero is 445.5 miles.
What is the most ecofriendly mode of transport between Mendoza and Santiago del Estero?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 176 kgs.
What is the cheapest mode of transport from Mendoza to Santiago del Estero?
You can get to Santiago del Estero with just $72 by taking a Bus from San Juan Mar del Plata.
What is the fastest way to get from Mendoza to Santiago del Estero?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago del Estero in just 5h 20m with a Flight from Aerolíneas Argentinas.
More routes to Mendoza and to Santiago del Estero
Looking for more options? Here you can see the most popular routes to Mendoza and to Santiago del Estero. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mendoza
- Bahía Blanca to Mendoza
- Bariloche to Mendoza
- Buenos Aires to Mendoza
- Córdoba, CD to Mendoza
- Corrientes to Mendoza
- La Serena to Mendoza
- Mar del Plata to Mendoza
- Puerto Madryn to Mendoza
- Resistencia to Mendoza
- Rosario, SF to Mendoza
- Salta to Mendoza
- San Miguel de Tucumán to Mendoza
- San Salvador de Jujuy, JJ to Mendoza
- Santiago del Estero to Mendoza
- Santiago, RM to Mendoza

