Bus Mendoza to Santiago del Estero - Compare all Companies

Compare all timetables for the bus from Mendoza to Santiago del Estero

Here is a selection of the cheapest bus trips from the schedule from Mendoza to Santiago del Estero from various bus operators like San Juan Mar del Plata, Andesmar or 20 de Junio for the next days.

today

$72

tomorrow

Saturday

$72

Sunday

$72

Monday

$72

Tuesday

Wednesday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	San Juan Mar del Plata	17h 10m	10:50 AM	Mendoza	Bus Station	4:00 AM	Santiago del Estero	Central Bus Station		Premium Economy	$72	A Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/4/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/5/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
	20 de Junio	19h 20m	8:30 PM	Mendoza	Bus Station	3:50 PM	Santiago del Estero	Central Bus Station		First Class	$104	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/4/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/5/2025 3:50:00 PM. 50 First Class ticket for $104 per person are available. Travel duration is 19h 20m

Did you know that if you travel from Mendoza to Santiago del Estero via San Fernando del Valle de Catamarca, you can save more than $21? You can find the corresponding connections below.
- Voyenbus
  
  24h 35m
  
  0
  
  1:00 PM
  
  Mendoza
  Bus Station
  
  11:25 PM
  
  San Fernando del Valle de Catamarca
  Bus Station
  
  0
  
  Premium Economy
  
  $26
  
  A Bus from Voyenbus goes from Bus Station, Mendoza (Argentina) at 12/5/2025 1:00:00 PM to Bus Station, San Fernando del Valle de Catamarca (Argentina) arriving at 12/5/2025 11:25:00 PM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 10h 25m
- Voyenbus
  
  5h 50m
  
  0
  
  7:45 AM
  
  San Fernando del Valle de Catamarca
  Bus Station
  
  1:35 PM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  Premium Economy
  
  $25
  
  A Bus from Voyenbus goes from Bus Station, San Fernando del Valle de Catamarca (Argentina) at 12/6/2025 7:45:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/6/2025 1:35:00 PM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 5h 50m
Travel time is 7h 25m longer, but you will save $21

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
San Juan Mar del Plata	17h 10m	10:50 AM	Mendoza	Bus Station	4:00 AM	Santiago del Estero	Central Bus Station	Premium Economy	$72	A Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/6/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
Andesmar	16h 5m	9:30 PM	Mendoza	Bus Station	1:35 PM	Santiago del Estero	Central Bus Station	Premium Economy	$73	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/6/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
20 de Junio	19h 20m	8:30 PM	Mendoza	Bus Station	3:50 PM	Santiago del Estero	Central Bus Station	First Class	$99	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/6/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/7/2025 3:50:00 PM. 50 First Class ticket for $99 per person are available. Travel duration is 19h 20m

Did you know that if you travel from Mendoza to Santiago del Estero via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
- Plataforma 10
  
  16h 45m
  
  0
  
  9:00 AM
  
  Mendoza
  Bus Station
  
  7:30 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $31
  
  A Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 12/8/2025 9:00:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 12/8/2025 7:30:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 10h 30m
- Plataforma 10
  
  5h 55m
  
  0
  
  7:50 PM
  
  Córdoba, CD
  Bus Station
  
  1:45 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Plataforma 10 goes from Bus Station, Córdoba, CD (Argentina) at 12/8/2025 7:50:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 1:45:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 55m
Travel time is 0h 40m longer, but you will save $24

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
San Juan Mar del Plata	17h 10m	10:50 AM	Mendoza	Bus Station	4:00 AM	Santiago del Estero	Central Bus Station	Premium Economy	$72	A Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/7/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
Andesmar	16h 5m	9:30 PM	Mendoza	Bus Station	1:35 PM	Santiago del Estero	Central Bus Station	Premium Economy	$73	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/7/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m
20 de Junio	19h 20m	8:30 PM	Mendoza	Bus Station	3:50 PM	Santiago del Estero	Central Bus Station	First Class	$99	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/7/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/8/2025 3:50:00 PM. 50 First Class ticket for $99 per person are available. Travel duration is 19h 20m

Did you know that if you travel from Mendoza to Santiago del Estero via Córdoba, CD, you can save more than $24? You can find the corresponding connections below.
- Plataforma 10
  
  16h 45m
  
  0
  
  9:00 AM
  
  Mendoza
  Bus Station
  
  7:30 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $31
  
  A Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 12/8/2025 9:00:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 12/8/2025 7:30:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 10h 30m
- Plataforma 10
  
  5h 55m
  
  0
  
  7:50 PM
  
  Córdoba, CD
  Bus Station
  
  1:45 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Plataforma 10 goes from Bus Station, Córdoba, CD (Argentina) at 12/8/2025 7:50:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 1:45:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 55m
Travel time is 0h 40m longer, but you will save $24

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	San Juan Mar del Plata	17h 10m	10:50 AM	Mendoza	Bus Station	4:00 AM	Santiago del Estero	Central Bus Station		Premium Economy	$72	A Bus from San Juan Mar del Plata goes from Bus Station, Mendoza (Argentina) at 12/8/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 4:00:00 AM. 50 Premium Economy ticket for $72 per person are available. Travel duration is 17h 10m
	Andesmar	16h 5m	9:30 PM	Mendoza	Bus Station	1:35 PM	Santiago del Estero	Central Bus Station		Premium Economy	$73	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/8/2025 9:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/9/2025 1:35:00 PM. 50 Premium Economy ticket for $73 per person are available. Travel duration is 16h 5m

Did you know that if you travel from Mendoza to Santiago del Estero via Córdoba, CD, you can save more than $28? You can find the corresponding connections below.
- Plataforma 10
  
  21h 40m
  
  0
  
  9:30 PM
  
  Mendoza
  Bus Station
  
  7:35 AM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $27
  
  A Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 12/9/2025 9:30:00 PM to Bus Station, Córdoba, CD (Argentina) arriving at 12/10/2025 7:35:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 5m
- Voyenbus
  
  5h 55m
  
  0
  
  1:15 PM
  
  Córdoba, CD
  Bus Station
  
  7:10 PM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  Premium Economy
  
  $17
  
  A Bus from Voyenbus goes from Bus Station, Córdoba, CD (Argentina) at 12/10/2025 1:15:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/10/2025 7:10:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 5h 55m
Travel time is 5h 35m longer, but you will save $28

Best Price Offer: The price for the cheapest bus from Mendoza to Santiago del Estero is $58 on 12/3/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Mendoza and Santiago del Estero

See here how frequent the connections between Mendoza and Santiago del Estero are, during different times and days of the week.

Sunday is the busiest day, with more than 10 daily buses from Mendoza to Santiago del Estero. Monday has instead the fewest connections, with only 3 daily coaches between Mendoza and Santiago del Estero.

The busiest time of the day is the Evening, with 16 buses from Mendoza to Santiago del Estero, while Morning sees the fewest connections between Mendoza and Santiago del Estero, with 13 offers.

Facts about the bus from Mendoza to Santiago del Estero

Compare all providers like San Juan Mar del Plata, Andesmar and 20 de Junio that travel 7 times every day by bus from Mendoza to Santiago del Estero in one click! Book your bus ticket from Mendoza to Santiago del Estero starting from $58!

Cheapest Bus	$58
Fastest Bus	16h 5m
Earliest Bus	10:50 AM
Latest Bus	9:30 PM
Daily Bus Routes	7 Ø
Distance	445.5 miles
Bus Companies	San Juan Mar del Plata, Andesmar and 20 de Junio

Cheapest bus connections from Mendoza to Santiago del Estero

Every day, 7 buses from 3 bus companies leave Mendoza for Santiago del Estero: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

$69

Friday 12/05

Saturday 12/06

$66

Sunday 12/07

$72

Monday 12/08

$72

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

Friday 12/12

$72

Saturday 12/13

$66

Sunday 12/14

Monday 12/15

Tuesday 12/16

$61

Wednesday 12/17

Thursday 12/18

$63

Friday 12/19

Saturday 12/20

$66

Sunday 12/21

$72

Monday 12/22

Tuesday 12/23

$72

Wednesday 12/24

Thursday 12/25

Friday 12/26

$72

Saturday 12/27

The cheapest time to travel from Mendoza to Santiago del Estero

See here on which day and which time of the day you can find the cheapest bus ticket from Mendoza to Santiago del Estero, for the next 30 days.

With a price starting from $63, Thursday is the cheapest day for a bus from Mendoza to Santiago del Estero. Sunday instead is the most expensive day with prices starting from $72.

Morning is the cheapest day time for bus tickets from Mendoza to Santiago del Estero, with $72. Evening is the most expensive time of the day with prices starting from $73.

How to save money travelling from Mendoza to Santiago del Estero

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mendoza to Santiago del Estero in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mendoza to Santiago del Estero, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mendoza to Santiago del Estero are also emptier.

All bus stations and stops in Mendoza and Santiago del Estero

In the map below, you can see where to find all bus stations in Mendoza and Santiago del Estero.

Bus Station

Juan B. Alberdi s/n

Hotel Internacional

Av. Sarmiento 720

Hotel Hyatt

Chile 1124

Hotel NH Cordillera

1324 1324

Casa Juri

Central Bus Station

Av. Roca Norte 100

Av. Libertad & Av. Aguirre

Ambargasta

El Saladillo

Regional Hospital "Dr. Ramón Carrillo"

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mendoza to Santiago del Estero? Compare all modes of transports from Mendoza to Santiago del Estero.

Service and Comfort on the bus from Mendoza to Santiago del Estero

Want to know which seat classes are available on the buses from Mendoza to Santiago del Estero? Or which bus companies serve the route Mendoza to Santiago del Estero? Below you will find answers to your questions.

FAQs about the Mendoza to Santiago del Estero bus

How much does a Mendoza Santiago del Estero bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $58 and takes 17h 10m to reach Santiago del Estero. Compare offers to save money!

How much could I save by comparing buses from Mendoza to Santiago del Estero?

This route is offered by 3 companies with a range of ticket prices between $58 and $112. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago del Estero.

On average, how many connections are available from Mendoza to Santiago del Estero each day?

Every day, the Mendoza to Santiago del Estero bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mendoza to Santiago del Estero take?

The fastest bus from Mendoza to Santiago del Estero is offered by Andesmar and takes 16h 5m. Bus tickets for this connection cost $73. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mendoza to Santiago del Estero?

The earliest bus arriving in Santiago del Estero from Mendoza starts at 10:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mendoza to Santiago del Estero?

The latest bus trip departing from Mendoza for Santiago del Estero starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mendoza Santiago del Estero route?

When traveling by bus from Mendoza to Santiago del Estero, passengers can travel with San Juan Mar del Plata, Andesmar and 20 de Junio. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mendoza and Santiago del Estero?

You can check all the direct connections between Mendoza and Santiago del Estero by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: San Juan Mar del Plata, Andesmar and 20 de Junio.

What can I take with me on the Mendoza to Santiago del Estero bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mendoza Santiago del Estero bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mendoza Santiago del Estero bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mendoza to Santiago del Estero on your planned travel date.

Available seat classes which are offered on the bus route Mendoza to Santiago del Estero

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Mendoza and to Santiago del Estero

Here’s an overview of the most popular bus routes to Mendoza and to Santiago del Estero. Simply click on the connection of your choice, and you will find all the details about your bus route!