Bus Buenos Aires to Santiago del Estero

Compare all timetables for the bus from Buenos Aires to Santiago del Estero

Here is a selection of the cheapest bus trips from the schedule from Buenos Aires to Santiago del Estero from various bus operators like Balut, Flecha Bus or Vosa for the next days.

today

$52

tomorrow

$48

Wednesday

$59

Thursday

$31

Friday

$34

Saturday

$48

Sunday

$48

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Crucero del Sur	15h 10m	10:00 PM	Buenos Aires	Retiro Bus Station	1:10 PM	Santiago del Estero	Central Bus Station	Premium Economy	$52	A Bus from Crucero del Sur goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/22/2025 10:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/23/2025 1:10:00 PM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 10m
Balut	15h 15m	2:15 PM	Buenos Aires	Retiro Bus Station	5:30 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/22/2025 2:15:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/23/2025 5:30:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 15m
Vosa	14h 0m	8:20 PM	Buenos Aires	Julio A. Roca Bus Stop	10:20 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Vosa goes from Julio A. Roca Bus Stop, Buenos Aires (Argentina) at 12/22/2025 8:20:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/23/2025 10:20:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 14h 0m
Flecha Bus	17h 50m	3:30 PM	Buenos Aires	Liniers Bus Station	9:20 AM	Santiago del Estero	Central Bus Station	Premium Economy	$60	A Bus from Flecha Bus goes from Liniers Bus Station, Buenos Aires (Argentina) at 12/22/2025 3:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/23/2025 9:20:00 AM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 17h 50m
20 de Junio	17h 15m	12:00 PM	Buenos Aires	Retiro Bus Station	5:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$63	A Bus from 20 de Junio goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/22/2025 12:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/23/2025 5:15:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 17h 15m

Did you know that if you travel from Buenos Aires to Santiago del Estero via Rosario, SF, you can save more than $22? You can find the corresponding connections below.
- Voyenbus
  
  18h 25m
  
  0
  
  7:00 AM
  
  Buenos Aires
  Retiro Bus Station
  
  11:10 AM
  
  Rosario, SF
  Bus Station
  
  0
  
  Premium Economy
  
  $22
  
  A Bus from Voyenbus goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/24/2025 7:00:00 AM to Bus Station, Rosario, SF (Argentina) arriving at 12/24/2025 11:10:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 10m
- Voyenbus
  
  10h 0m
  
  0
  
  3:25 PM
  
  Rosario, SF
  Bus Station
  
  1:25 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  First Class
  
  $9
  
  A Bus from Voyenbus goes from Bus Station, Rosario, SF (Argentina) at 12/24/2025 3:25:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 1:25:00 AM. 50 First Class ticket for $9 per person are available. Travel duration is 10h 0m
Travel time is 4h 25m longer, but you will save $22

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
La Unión	19h 0m	11:00 AM	Buenos Aires	Retiro Bus Station	6:00 AM	Santiago del Estero	Central Bus Station	Premium Economy	$48	A Bus from La Unión goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/23/2025 11:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/24/2025 6:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 19h 0m
Crucero del Sur	15h 10m	10:00 PM	Buenos Aires	Retiro Bus Station	1:10 PM	Santiago del Estero	Central Bus Station	Premium Economy	$52	A Bus from Crucero del Sur goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/23/2025 10:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/24/2025 1:10:00 PM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 10m
Balut	15h 0m	10:25 AM	Buenos Aires	Terminal de Ómnibus Dellepiane	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Terminal de Ómnibus Dellepiane, Buenos Aires (Argentina) at 12/23/2025 10:25:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/24/2025 1:25:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 0m
Flecha Bus	15h 35m	5:35 PM	Buenos Aires	Retiro Bus Station	9:10 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Flecha Bus goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/23/2025 5:35:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/24/2025 9:10:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 35m
Vosa	13h 50m	8:30 PM	Buenos Aires	Julio A. Roca Bus Stop	10:20 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Vosa goes from Julio A. Roca Bus Stop, Buenos Aires (Argentina) at 12/23/2025 8:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/24/2025 10:20:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 13h 50m

Did you know that if you travel from Buenos Aires to Santiago del Estero via Rosario, SF, you can save more than $19? You can find the corresponding connections below.
- Voyenbus
  
  18h 40m
  
  0
  
  10:50 AM
  
  Buenos Aires
  Liniers Bus Station
  
  3:25 PM
  
  Rosario, SF
  Bus Station
  
  0
  
  Premium Economy
  
  $21
  
  A Bus from Voyenbus goes from Liniers Bus Station, Buenos Aires (Argentina) at 12/24/2025 10:50:00 AM to Bus Station, Rosario, SF (Argentina) arriving at 12/24/2025 3:25:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 4h 35m
- Voyenbus
  
  10h 0m
  
  0
  
  7:30 PM
  
  Rosario, SF
  Bus Station
  
  5:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  First Class
  
  $9
  
  A Bus from Voyenbus goes from Bus Station, Rosario, SF (Argentina) at 12/24/2025 7:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 5:30:00 AM. 50 First Class ticket for $9 per person are available. Travel duration is 10h 0m
Travel time is 4h 50m longer, but you will save $19

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Balut	15h 25m	10:00 AM	Buenos Aires	Retiro Bus Station	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/24/2025 10:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 1:25:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 25m
Balut	15h 15m	2:15 PM	Buenos Aires	Retiro Bus Station	5:30 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/24/2025 2:15:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 5:30:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 15m
Balut	15h 0m	10:25 AM	Buenos Aires	Terminal de Ómnibus Dellepiane	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Terminal de Ómnibus Dellepiane, Buenos Aires (Argentina) at 12/24/2025 10:25:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 1:25:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 0m
Balut	14h 45m	2:45 PM	Buenos Aires	Terminal de Ómnibus Dellepiane	5:30 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Terminal de Ómnibus Dellepiane, Buenos Aires (Argentina) at 12/24/2025 2:45:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 5:30:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 14h 45m
Balut	14h 35m	10:50 AM	Buenos Aires	Liniers Bus Station	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Liniers Bus Station, Buenos Aires (Argentina) at 12/24/2025 10:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 1:25:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 14h 35m

Did you know that if you travel from Buenos Aires to Santiago del Estero via Rosario, SF, you can save more than $30? You can find the corresponding connections below.
- Voyenbus
  
  18h 40m
  
  0
  
  10:50 AM
  
  Buenos Aires
  Liniers Bus Station
  
  3:25 PM
  
  Rosario, SF
  Bus Station
  
  0
  
  Premium Economy
  
  $21
  
  A Bus from Voyenbus goes from Liniers Bus Station, Buenos Aires (Argentina) at 12/24/2025 10:50:00 AM to Bus Station, Rosario, SF (Argentina) arriving at 12/24/2025 3:25:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 4h 35m
- Voyenbus
  
  10h 0m
  
  0
  
  7:30 PM
  
  Rosario, SF
  Bus Station
  
  5:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  First Class
  
  $9
  
  A Bus from Voyenbus goes from Bus Station, Rosario, SF (Argentina) at 12/24/2025 7:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 5:30:00 AM. 50 First Class ticket for $9 per person are available. Travel duration is 10h 0m
Travel time is 4h 5m longer, but you will save $30

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
La Unión	19h 0m	11:00 AM	Buenos Aires	Retiro Bus Station	6:00 AM	Santiago del Estero	Central Bus Station	Premium Economy	$31	A Bus from La Unión goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/25/2025 11:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/26/2025 6:00:00 AM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 19h 0m
20 de Junio	17h 15m	12:00 PM	Buenos Aires	Retiro Bus Station	5:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$39	A Bus from 20 de Junio goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/25/2025 12:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/26/2025 5:15:00 AM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 17h 15m
Balut	15h 0m	10:25 AM	Buenos Aires	Terminal de Ómnibus Dellepiane	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$44	A Bus from Balut goes from Terminal de Ómnibus Dellepiane, Buenos Aires (Argentina) at 12/25/2025 10:25:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/26/2025 1:25:00 AM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 15h 0m
La Veloz del Norte	18h 25m	9:50 AM	Buenos Aires	Terminal de Ómnibus Dellepiane	4:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$49	A Bus from La Veloz del Norte goes from Terminal de Ómnibus Dellepiane, Buenos Aires (Argentina) at 12/25/2025 9:50:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/26/2025 4:15:00 AM. 50 Premium Economy ticket for $49 per person are available. Travel duration is 18h 25m
Flecha Bus	15h 45m	4:30 PM	Buenos Aires	Retiro Bus Station	8:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$56	A Bus from Flecha Bus goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/25/2025 4:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/26/2025 8:15:00 AM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
La Unión	19h 0m	11:00 AM	Buenos Aires	Retiro Bus Station	6:00 AM	Santiago del Estero	Central Bus Station	Premium Economy	$34	A Bus from La Unión goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/26/2025 11:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/27/2025 6:00:00 AM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 19h 0m
Balut	15h 25m	10:00 AM	Buenos Aires	Retiro Bus Station	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$44	A Bus from Balut goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/26/2025 10:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/27/2025 1:25:00 AM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 15h 25m
20 de Junio	17h 15m	12:00 PM	Buenos Aires	Retiro Bus Station	5:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$50	A Bus from 20 de Junio goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/26/2025 12:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/27/2025 5:15:00 AM. 50 Premium Economy ticket for $50 per person are available. Travel duration is 17h 15m
Crucero del Sur	15h 10m	10:00 PM	Buenos Aires	Retiro Bus Station	1:10 PM	Santiago del Estero	Central Bus Station	Premium Economy	$52	A Bus from Crucero del Sur goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/26/2025 10:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/27/2025 1:10:00 PM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 10m
Flecha Bus	15h 45m	4:30 PM	Buenos Aires	Retiro Bus Station	8:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$56	A Bus from Flecha Bus goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/26/2025 4:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/27/2025 8:15:00 AM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 45m

Did you know that if you travel from Buenos Aires to Santiago del Estero via Rosario, SF, you can save more than $5? You can find the corresponding connections below.
- Voyenbus
  
  18h 40m
  
  0
  
  10:50 AM
  
  Buenos Aires
  Liniers Bus Station
  
  3:25 PM
  
  Rosario, SF
  Bus Station
  
  0
  
  Premium Economy
  
  $21
  
  A Bus from Voyenbus goes from Liniers Bus Station, Buenos Aires (Argentina) at 12/24/2025 10:50:00 AM to Bus Station, Rosario, SF (Argentina) arriving at 12/24/2025 3:25:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 4h 35m
- Voyenbus
  
  10h 0m
  
  0
  
  7:30 PM
  
  Rosario, SF
  Bus Station
  
  5:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  First Class
  
  $9
  
  A Bus from Voyenbus goes from Bus Station, Rosario, SF (Argentina) at 12/24/2025 7:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 5:30:00 AM. 50 First Class ticket for $9 per person are available. Travel duration is 10h 0m
Travel time is 3h 30m longer, but you will save $5

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
La Unión	19h 0m	11:00 AM	Buenos Aires	Retiro Bus Station	6:00 AM	Santiago del Estero	Central Bus Station	Premium Economy	$48	A Bus from La Unión goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/27/2025 11:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/28/2025 6:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 19h 0m
Crucero del Sur	15h 10m	10:00 PM	Buenos Aires	Retiro Bus Station	1:10 PM	Santiago del Estero	Central Bus Station	Premium Economy	$52	A Bus from Crucero del Sur goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/27/2025 10:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/28/2025 1:10:00 PM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 10m
Flecha Bus	15h 45m	4:30 PM	Buenos Aires	Retiro Bus Station	8:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$56	A Bus from Flecha Bus goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/27/2025 4:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/28/2025 8:15:00 AM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 45m
Balut	15h 0m	10:25 AM	Buenos Aires	Terminal de Ómnibus Dellepiane	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Terminal de Ómnibus Dellepiane, Buenos Aires (Argentina) at 12/27/2025 10:25:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/28/2025 1:25:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 0m
Vosa	14h 0m	8:20 PM	Buenos Aires	Julio A. Roca Bus Stop	10:20 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Vosa goes from Julio A. Roca Bus Stop, Buenos Aires (Argentina) at 12/27/2025 8:20:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/28/2025 10:20:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 14h 0m

Did you know that if you travel from Buenos Aires to Santiago del Estero via Rosario, SF, you can save more than $19? You can find the corresponding connections below.
- Voyenbus
  
  18h 40m
  
  0
  
  10:50 AM
  
  Buenos Aires
  Liniers Bus Station
  
  3:25 PM
  
  Rosario, SF
  Bus Station
  
  0
  
  Premium Economy
  
  $21
  
  A Bus from Voyenbus goes from Liniers Bus Station, Buenos Aires (Argentina) at 12/24/2025 10:50:00 AM to Bus Station, Rosario, SF (Argentina) arriving at 12/24/2025 3:25:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 4h 35m
- Voyenbus
  
  10h 0m
  
  0
  
  7:30 PM
  
  Rosario, SF
  Bus Station
  
  5:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  First Class
  
  $9
  
  A Bus from Voyenbus goes from Bus Station, Rosario, SF (Argentina) at 12/24/2025 7:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 5:30:00 AM. 50 First Class ticket for $9 per person are available. Travel duration is 10h 0m
Travel time is 4h 40m longer, but you will save $19

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Transporte La Union	19h 0m	11:00 AM	Buenos Aires	Retiro Bus Station	6:00 AM	Santiago del Estero	Central Bus Station	Premium Economy	$48	A Bus from Transporte La Union goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/28/2025 11:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/29/2025 6:00:00 AM. 50 Premium Economy ticket for $48 per person are available. Travel duration is 19h 0m
Flecha Bus	15h 45m	4:30 PM	Buenos Aires	Retiro Bus Station	8:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$56	A Bus from Flecha Bus goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/28/2025 4:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/29/2025 8:15:00 AM. 50 Premium Economy ticket for $56 per person are available. Travel duration is 15h 45m
Balut	15h 25m	10:00 AM	Buenos Aires	Retiro Bus Station	1:25 AM	Santiago del Estero	Central Bus Station	Premium Economy	$59	A Bus from Balut goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/28/2025 10:00:00 AM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/29/2025 1:25:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 25m
20 de Junio	17h 15m	12:00 PM	Buenos Aires	Retiro Bus Station	5:15 AM	Santiago del Estero	Central Bus Station	Premium Economy	$63	A Bus from 20 de Junio goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/28/2025 12:00:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/29/2025 5:15:00 AM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 17h 15m
Vosa	13h 45m	6:30 PM	Buenos Aires	Retiro Bus Station	8:15 AM	Santiago del Estero	Central Bus Station	First Class	$75	A Bus from Vosa goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/28/2025 6:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/29/2025 8:15:00 AM. 50 First Class ticket for $75 per person are available. Travel duration is 13h 45m

Did you know that if you travel from Buenos Aires to Santiago del Estero via Rosario, SF, you can save more than $19? You can find the corresponding connections below.
- Voyenbus
  
  18h 40m
  
  0
  
  10:50 AM
  
  Buenos Aires
  Liniers Bus Station
  
  3:25 PM
  
  Rosario, SF
  Bus Station
  
  0
  
  Premium Economy
  
  $21
  
  A Bus from Voyenbus goes from Liniers Bus Station, Buenos Aires (Argentina) at 12/24/2025 10:50:00 AM to Bus Station, Rosario, SF (Argentina) arriving at 12/24/2025 3:25:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 4h 35m
- Voyenbus
  
  10h 0m
  
  0
  
  7:30 PM
  
  Rosario, SF
  Bus Station
  
  5:30 AM
  
  Santiago del Estero
  Central Bus Station
  
  0
  
  First Class
  
  $9
  
  A Bus from Voyenbus goes from Bus Station, Rosario, SF (Argentina) at 12/24/2025 7:30:00 PM to Central Bus Station, Santiago del Estero (Argentina) arriving at 12/25/2025 5:30:00 AM. 50 First Class ticket for $9 per person are available. Travel duration is 10h 0m
Travel time is 4h 55m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from Buenos Aires to Santiago del Estero is $31 on 12/25/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Buenos Aires and Santiago del Estero

See here how frequent the connections between Buenos Aires and Santiago del Estero are, during different times and days of the week.

Saturday is the busiest day, with more than 97 daily buses from Buenos Aires to Santiago del Estero. Wednesday has instead the fewest connections, with only 20 daily coaches between Buenos Aires and Santiago del Estero.

The busiest time of the day is the Evening, with 244 buses from Buenos Aires to Santiago del Estero, while Morning sees the fewest connections between Buenos Aires and Santiago del Estero, with 94 offers.

Facts about the bus from Buenos Aires to Santiago del Estero

Compare all providers like Balut, Flecha Bus and Vosa that travel 73 times every day by bus from Buenos Aires to Santiago del Estero in one click! Book your bus ticket from Buenos Aires to Santiago del Estero starting from $31!

Cheapest Bus	$31
Fastest Bus	12h 5m
Earliest Bus	12:00 PM
Latest Bus	11:05 PM
Daily Bus Routes	73 Ø
Distance	586.1 miles
Bus Companies	Balut, Flecha Bus, Vosa, 20 de Junio, Rutatlántica, Crucero del Sur, La Veloz del Norte, La Unión, Transporte La Union and Almirante Brown

Cheapest bus connections from Buenos Aires to Santiago del Estero

Every day, 73 buses from 10 bus companies leave Buenos Aires for Santiago del Estero: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/22/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

$48

Tuesday 12/23

$48

Wednesday 12/24

$59

Thursday 12/25

$48

Friday 12/26

$48

Saturday 12/27

$56

Sunday 12/28

$48

Monday 12/29

$48

Tuesday 12/30

$49

Wednesday 12/31

$59

Thursday 01/01

$48

Friday 01/02

$48

Saturday 01/03

$49

Sunday 01/04

$48

Monday 01/05

$48

Tuesday 01/06

$49

Wednesday 01/07

$48

Thursday 01/08

$48

Friday 01/09

$49

Saturday 01/10

$48

Sunday 01/11

$48

Monday 01/12

$59

Tuesday 01/13

$42

Wednesday 01/14

$42

Thursday 01/15

$48

Friday 01/16

$42

Saturday 01/17

The cheapest time to travel from Buenos Aires to Santiago del Estero

See here on which day and which time of the day you can find the cheapest bus ticket from Buenos Aires to Santiago del Estero, for the next 30 days.

With a price starting from $31, Thursday is the cheapest day for a bus from Buenos Aires to Santiago del Estero. Monday instead is the most expensive day with prices starting from $48.

Morning is the cheapest day time for bus tickets from Buenos Aires to Santiago del Estero, with $31. Afternoon is the most expensive time of the day with prices starting from $39.

How to save money travelling from Buenos Aires to Santiago del Estero

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buenos Aires to Santiago del Estero in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buenos Aires to Santiago del Estero, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buenos Aires to Santiago del Estero are also emptier.

Beloved bus companies from Buenos Aires to Santiago del Estero

These are the most booked bus companies between Buenos Aires to Santiago del Estero from our users.

20 de Junio from Buenos Aires to Santiago del Estero

Here you will find the key facts about the 20 de Junio bus route Buenos Aires to Santiago del Estero:

Cheapest Price	$39
Fastest Bus	17h 5m
Earliest Bus	12:00 PM
Last Bus	9:30 PM
Daily Connections	8 Ø
Found on	12/22/2025

Balut from Buenos Aires to Santiago del Estero

Here you will find the key facts about the Balut bus route Buenos Aires to Santiago del Estero:

Cheapest Price	$44
Fastest Bus	13h 25m
Earliest Bus	2:15 PM
Last Bus	11:05 PM
Daily Connections	36 Ø
Found on	12/22/2025

Latest reviews for bus companies on the route Buenos Aires - Santiago del Estero

Nicole , 10/14/2025

Caía agua por los parlantes y rejilla de ventilación arriba de nuestras cabezas nos pudimos cambiar cuando bajo más gente. Sucio realmente (paredes de los costados, asientos, piso de abajo inundado po ... Caía agua por los parlantes y rejilla de ventilación arriba de nuestras cabezas nos pudimos cambiar cuando bajo más gente. Sucio realmente (paredes de los costados, asientos, piso de abajo inundado porque el baño empezó a largar agua por el hindoro por ende tremendo olor). Nos atendió dos personas distintas al momento de los boletos la chica un amor el pibe el trabajo que hizo lo hizo mal y ella tuvo que repararlo. Por ende de principio a fin era las ganas de llegar para nunca mas viajar por esa línea. Otra cosa la "comodidad" del semi cama es nula, realmente vale la pena pagar un poco más e ir más cómodos en cama. Grabamos videos del agua cayendo pero acá no da posibilidad de subirlo

All bus stations and stops in Buenos Aires and Santiago del Estero

In the map below, you can see where to find all bus stations in Buenos Aires and Santiago del Estero.

Liniers Bus Station

Avenida General Paz , Liniers 10868/76

Retiro Bus Station

Av. Antártida Argentina y Calle 10 - Capital Federal. 10

Terminal de Ómnibus Dellepiane

Teniente General Luís Dellepiane Av. Perito Moreno 3950, Villa Soldati, Ciudad de Buenos Aires

Villa Tesei

Reyes Catolicos 246

Thames - Panamericana

Central Bus Station

Av. Roca Norte 100

Av. Libertad & Av. Aguirre

Ambargasta

Bus Stop

RN9

El Saladillo

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Buenos Aires to Santiago del Estero? Compare all modes of transports from Buenos Aires to Santiago del Estero.

Service and Comfort on the bus from Buenos Aires to Santiago del Estero

Want to know which seat classes are available on the buses from Buenos Aires to Santiago del Estero? Or which bus companies serve the route Buenos Aires to Santiago del Estero? Below you will find answers to your questions.

FAQs about the Buenos Aires to Santiago del Estero bus

How much does a Buenos Aires Santiago del Estero bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $31 and takes 19h 0m to reach Santiago del Estero. Compare offers to save money!

How much could I save by comparing buses from Buenos Aires to Santiago del Estero?

This route is offered by 10 companies with a range of ticket prices between $31 and $111. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago del Estero.

On average, how many connections are available from Buenos Aires to Santiago del Estero each day?

Every day, the Buenos Aires to Santiago del Estero bus route is served by approximately 73 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buenos Aires to Santiago del Estero take?

The fastest bus from Buenos Aires to Santiago del Estero is offered by Vosa and takes 12h 5m. Bus tickets for this connection cost $87. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buenos Aires to Santiago del Estero?

The earliest bus arriving in Santiago del Estero from Buenos Aires starts at 12:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buenos Aires to Santiago del Estero?

The latest bus trip departing from Buenos Aires for Santiago del Estero starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buenos Aires Santiago del Estero route?

When traveling by bus from Buenos Aires to Santiago del Estero, passengers can travel with Balut, Flecha Bus and Vosa. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buenos Aires and Santiago del Estero?

You can check all the direct connections between Buenos Aires and Santiago del Estero by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Balut, Flecha Bus and Vosa.

What can I take with me on the Buenos Aires to Santiago del Estero bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buenos Aires Santiago del Estero bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buenos Aires Santiago del Estero bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buenos Aires to Santiago del Estero on your planned travel date.

How does CheckMyBus find the best bus deals from Buenos Aires to Santiago del Estero?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 73 daily trips between Buenos Aires and Santiago del Estero. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Buenos Aires to Santiago del Estero?

Prices and availability for 73 trips between Buenos Aires and Santiago del Estero change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Buenos Aires to Santiago del Estero

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Buenos Aires and to Santiago del Estero

Here’s an overview of the most popular bus routes to Buenos Aires and to Santiago del Estero. Simply click on the connection of your choice, and you will find all the details about your bus route!