Bus Santa Fe, SF to Mendoza: Compare prices and save money

Compare all timetables for the bus from Santa Fe, SF to Mendoza

Here is a selection of the cheapest bus trips from the schedule from Santa Fe, SF to Mendoza from various bus operators like 20 de Junio, Andesmar or Flecha Bus for the next days.

today

tomorrow

$57

Friday

$46

Saturday

$57

Sunday

$57

Monday

$57

Tuesday

$57

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 20m	6:30 AM	Santa Fe, SF	Central Bus Station	8:50 PM	Mendoza	Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/18/2025 6:30:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 8:50:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 20m
Andesmar	14h 52m	9:00 PM	Santa Fe, SF	Central Bus Station	11:52 AM	Mendoza	Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/18/2025 9:00:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/19/2025 11:52:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 52m
20 de Junio	16h 0m	2:00 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Mendoza	Bus Station	Premium Economy	$67	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/18/2025 2:00:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/18/2025 6:00:00 PM. 50 Premium Economy ticket for $67 per person are available. Travel duration is 16h 0m
20 de Junio	15h 30m	5:30 PM	Santa Fe, SF	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$67	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/18/2025 5:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/19/2025 9:00:00 AM. 50 Premium Economy ticket for $67 per person are available. Travel duration is 15h 30m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
20 de Junio	15h 30m	5:30 PM	Santa Fe, SF	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$46	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/19/2025 5:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/20/2025 9:00:00 AM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 15h 30m
Flecha Bus	14h 20m	6:30 AM	Santa Fe, SF	Central Bus Station	8:50 PM	Mendoza	Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/19/2025 6:30:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/19/2025 8:50:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 20m
20 de Junio	16h 0m	2:00 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Mendoza	Bus Station	Premium Economy	$64	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/19/2025 2:00:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/19/2025 6:00:00 PM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 16h 0m
Andesmar	14h 52m	9:00 PM	Santa Fe, SF	Central Bus Station	11:52 AM	Mendoza	Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/19/2025 9:00:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/20/2025 11:52:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 52m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 20m	6:30 AM	Santa Fe, SF	Central Bus Station	8:50 PM	Mendoza	Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/20/2025 6:30:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/20/2025 8:50:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 20m
Andesmar	14h 52m	9:00 PM	Santa Fe, SF	Central Bus Station	11:52 AM	Mendoza	Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/20/2025 9:00:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/21/2025 11:52:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 52m
20 de Junio	16h 0m	2:00 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/20/2025 2:00:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/20/2025 6:00:00 PM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 16h 0m
20 de Junio	15h 30m	5:30 PM	Santa Fe, SF	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/20/2025 5:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/21/2025 9:00:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 15h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 20m	6:30 AM	Santa Fe, SF	Central Bus Station	8:50 PM	Mendoza	Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/21/2025 6:30:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/21/2025 8:50:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 20m
Andesmar	14h 52m	9:00 PM	Santa Fe, SF	Central Bus Station	11:52 AM	Mendoza	Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/21/2025 9:00:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/22/2025 11:52:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 52m
20 de Junio	16h 0m	2:00 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/21/2025 2:00:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/21/2025 6:00:00 PM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 16h 0m
20 de Junio	15h 30m	5:30 PM	Santa Fe, SF	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/21/2025 5:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/22/2025 9:00:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 15h 30m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 20m	6:30 AM	Santa Fe, SF	Central Bus Station	8:50 PM	Mendoza	Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/22/2025 6:30:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/22/2025 8:50:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 20m
Andesmar	14h 52m	9:00 PM	Santa Fe, SF	Central Bus Station	11:52 AM	Mendoza	Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/22/2025 9:00:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/23/2025 11:52:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 52m
20 de Junio	16h 0m	2:00 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/22/2025 2:00:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/22/2025 6:00:00 PM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 16h 0m
20 de Junio	15h 30m	5:30 PM	Santa Fe, SF	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/22/2025 5:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/23/2025 9:00:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 15h 30m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 20m	6:30 AM	Santa Fe, SF	Central Bus Station	8:50 PM	Mendoza	Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/23/2025 6:30:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/23/2025 8:50:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 20m
Flecha Bus	14h 20m	6:35 AM	Santa Fe, SF	Central Bus Station	8:55 PM	Mendoza	Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/23/2025 6:35:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/23/2025 8:55:00 PM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 20m
Andesmar	14h 52m	9:00 PM	Santa Fe, SF	Central Bus Station	11:52 AM	Mendoza	Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/23/2025 9:00:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/24/2025 11:52:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 52m
20 de Junio	16h 0m	2:00 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/23/2025 2:00:00 AM to Bus Station, Mendoza (Argentina) arriving at 12/23/2025 6:00:00 PM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 16h 0m
20 de Junio	15h 30m	5:30 PM	Santa Fe, SF	Central Bus Station	9:00 AM	Mendoza	Bus Station	Premium Economy	$75	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 12/23/2025 5:30:00 PM to Bus Station, Mendoza (Argentina) arriving at 12/24/2025 9:00:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 15h 30m

Best Price Offer: The price for the cheapest bus from Santa Fe, SF to Mendoza is $46 on 12/19/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Santa Fe, SF and Mendoza

See here how frequent the connections between Santa Fe, SF and Mendoza are, during different times and days of the week.

Sunday is the busiest day, with more than 19 daily buses from Santa Fe, SF to Mendoza. Tuesday has instead the fewest connections, with only 13 daily coaches between Santa Fe, SF and Mendoza.

The busiest time of the day is the Evening, with 28 buses from Santa Fe, SF to Mendoza, while Morning sees the fewest connections between Santa Fe, SF and Mendoza, with 12 offers.

Facts about the bus from Santa Fe, SF to Mendoza

Compare all providers like 20 de Junio, Andesmar and Flecha Bus that travel 14 times every day by bus from Santa Fe, SF to Mendoza in one click! Book your bus ticket from Santa Fe, SF to Mendoza starting from $46!

Cheapest Bus	$46
Fastest Bus	14h 20m
Earliest Bus	2:00 AM
Latest Bus	9:00 PM
Daily Bus Routes	14 Ø
Distance	484.2 miles
Bus Companies	20 de Junio, Andesmar and Flecha Bus

Cheapest bus connections from Santa Fe, SF to Mendoza

Every day, 14 buses from 3 bus companies leave Santa Fe, SF for Mendoza: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$57

Friday 12/19

$57

Saturday 12/20

$66

Sunday 12/21

$66

Monday 12/22

$57

Tuesday 12/23

$66

Wednesday 12/24

$77

Thursday 12/25

$66

Friday 12/26

$57

Saturday 12/27

$57

Sunday 12/28

$57

Monday 12/29

$57

Tuesday 12/30

$57

Wednesday 12/31

$57

Thursday 01/01

$66

Friday 01/02

$57

Saturday 01/03

$57

Sunday 01/04

$57

Monday 01/05

$57

Tuesday 01/06

$57

Wednesday 01/07

$57

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Santa Fe, SF to Mendoza

See here on which day and which time of the day you can find the cheapest bus ticket from Santa Fe, SF to Mendoza, for the next 30 days.

With a price starting from $46, Friday is the cheapest day for a bus from Santa Fe, SF to Mendoza. Sunday instead is the most expensive day with prices starting from $57.

Afternoon is the cheapest day time for bus tickets from Santa Fe, SF to Mendoza, with $46. Evening is the most expensive time of the day with prices starting from $66.

How to save money travelling from Santa Fe, SF to Mendoza

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Fe, SF to Mendoza in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Fe, SF to Mendoza, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Fe, SF to Mendoza are also emptier.

Beloved bus companies from Santa Fe, SF to Mendoza

These are the most booked bus companies between Santa Fe, SF to Mendoza from our users.

20 de Junio from Santa Fe, SF to Mendoza

Here you will find the key facts about the 20 de Junio bus route Santa Fe, SF to Mendoza:

Cheapest Price	$46
Fastest Bus	15h 30m
Earliest Bus	2:00 AM
Last Bus	5:30 PM
Daily Connections	8 Ø
Found on	12/15/2025

All bus stations and stops in Santa Fe, SF and Mendoza

In the map below, you can see where to find all bus stations in Santa Fe, SF and Mendoza.

Central Bus Station

Gral. Manuel Belgrano 2910

Bus Stop

Las Avispas

Córdoba

Bus Station

Juan B. Alberdi s/n

Hotel Internacional

Av. Sarmiento 720

Hotel Hyatt

Chile 1124

Hotel NH Cordillera

1324 1324

Casa Juri

Service and Comfort on the bus from Santa Fe, SF to Mendoza

Want to know which seat classes are available on the buses from Santa Fe, SF to Mendoza? Or which bus companies serve the route Santa Fe, SF to Mendoza? Below you will find answers to your questions.

FAQs about the Santa Fe, SF to Mendoza bus

How much does a Santa Fe, SF Mendoza bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $46 and takes 15h 30m to reach Mendoza. Compare offers to save money!

How much could I save by comparing buses from Santa Fe, SF to Mendoza?

This route is offered by 3 companies with a range of ticket prices between $46 and $104. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mendoza.

On average, how many connections are available from Santa Fe, SF to Mendoza each day?

Every day, the Santa Fe, SF to Mendoza bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Fe, SF to Mendoza take?

The fastest bus from Santa Fe, SF to Mendoza is offered by Flecha Bus and takes 14h 20m. Bus tickets for this connection cost $57. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Fe, SF to Mendoza?

The earliest bus arriving in Mendoza from Santa Fe, SF starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Fe, SF to Mendoza?

The latest bus trip departing from Santa Fe, SF for Mendoza starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Fe, SF Mendoza route?

When traveling by bus from Santa Fe, SF to Mendoza, passengers can travel with 20 de Junio, Andesmar and Flecha Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Fe, SF and Mendoza?

You can check all the direct connections between Santa Fe, SF and Mendoza by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: 20 de Junio, Andesmar and Flecha Bus.

What can I take with me on the Santa Fe, SF to Mendoza bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Fe, SF Mendoza bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Fe, SF Mendoza bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Fe, SF to Mendoza on your planned travel date.

How does CheckMyBus find the best bus deals from Santa Fe, SF to Mendoza?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Santa Fe, SF and Mendoza. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santa Fe, SF to Mendoza?

Prices and availability for 14 trips between Santa Fe, SF and Mendoza change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santa Fe, SF to Mendoza

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santa Fe, SF and to Mendoza

Here’s an overview of the most popular bus routes to Santa Fe, SF and to Mendoza. Simply click on the connection of your choice, and you will find all the details about your bus route!