Bus Puerto Iguazú to Santa Fe, SF - Compare all Companies

Compare all timetables for the bus from Puerto Iguazú to Santa Fe, SF

Here is a selection of the cheapest bus trips from the schedule from Puerto Iguazú to Santa Fe, SF from various bus operators like Rio Uruguay or Expreso Singer for the next days.

today

$12

tomorrow

$12

Sunday

$77

Monday

$77

Tuesday

$12

Wednesday

$12

Thursday

$12

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Expreso Singer	16h 20m	4:00 PM	Puerto Iguazú	Bus Station	8:20 AM	Santa Fe, SF	Central Bus Station	First Class	$12	A Bus from Expreso Singer goes from Bus Station, Puerto Iguazú (Argentina) at 12/5/2025 4:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 8:20:00 AM. 50 First Class ticket for $12 per person are available. Travel duration is 16h 20m
Rio Uruguay	17h 30m	7:30 AM	Puerto Iguazú	Bus Station	1:00 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/5/2025 7:30:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 1:00:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 17h 30m
Rio Uruguay	16h 45m	12:00 PM	Puerto Iguazú	Bus Station	4:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/5/2025 12:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 4:45:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 16h 45m
Rio Uruguay	16h 0m	2:00 PM	Puerto Iguazú	Bus Station	6:00 AM	Santa Fe, SF	Central Bus Station	First Class	$84	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/5/2025 2:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 6:00:00 AM. 50 First Class ticket for $84 per person are available. Travel duration is 16h 0m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Expreso Singer	16h 20m	4:00 PM	Puerto Iguazú	Bus Station	8:20 AM	Santa Fe, SF	Central Bus Station	First Class	$12	A Bus from Expreso Singer goes from Bus Station, Puerto Iguazú (Argentina) at 12/6/2025 4:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 8:20:00 AM. 50 First Class ticket for $12 per person are available. Travel duration is 16h 20m
Rio Uruguay	17h 30m	7:30 AM	Puerto Iguazú	Bus Station	1:00 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/6/2025 7:30:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 1:00:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 17h 30m
Rio Uruguay	16h 45m	12:00 PM	Puerto Iguazú	Bus Station	4:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/6/2025 12:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 4:45:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 16h 45m
Rio Uruguay	16h 0m	2:00 PM	Puerto Iguazú	Bus Station	6:00 AM	Santa Fe, SF	Central Bus Station	First Class	$84	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/6/2025 2:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 6:00:00 AM. 50 First Class ticket for $84 per person are available. Travel duration is 16h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Rio Uruguay	17h 30m	7:30 AM	Puerto Iguazú	Bus Station	1:00 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/7/2025 7:30:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 1:00:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 17h 30m
Rio Uruguay	16h 45m	12:00 PM	Puerto Iguazú	Bus Station	4:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/7/2025 12:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 4:45:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 16h 45m
Rio Uruguay	16h 0m	2:00 PM	Puerto Iguazú	Bus Station	6:00 AM	Santa Fe, SF	Central Bus Station	First Class	$84	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/7/2025 2:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 6:00:00 AM. 50 First Class ticket for $84 per person are available. Travel duration is 16h 0m
Expreso Singer	16h 20m	4:00 PM	Puerto Iguazú	Bus Station	8:20 AM	Santa Fe, SF	Central Bus Station	First Class	$96	A Bus from Expreso Singer goes from Bus Station, Puerto Iguazú (Argentina) at 12/7/2025 4:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 8:20:00 AM. 50 First Class ticket for $96 per person are available. Travel duration is 16h 20m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Rio Uruguay	17h 30m	7:30 AM	Puerto Iguazú	Bus Station	1:00 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/8/2025 7:30:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 1:00:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 17h 30m
Rio Uruguay	16h 45m	12:00 PM	Puerto Iguazú	Bus Station	4:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/8/2025 12:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 4:45:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 16h 45m
Rio Uruguay	16h 0m	2:00 PM	Puerto Iguazú	Bus Station	6:00 AM	Santa Fe, SF	Central Bus Station	First Class	$84	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/8/2025 2:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 6:00:00 AM. 50 First Class ticket for $84 per person are available. Travel duration is 16h 0m
Expreso Singer	16h 20m	4:00 PM	Puerto Iguazú	Bus Station	8:20 AM	Santa Fe, SF	Central Bus Station	First Class	$96	A Bus from Expreso Singer goes from Bus Station, Puerto Iguazú (Argentina) at 12/8/2025 4:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 8:20:00 AM. 50 First Class ticket for $96 per person are available. Travel duration is 16h 20m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Expreso Singer	16h 20m	4:00 PM	Puerto Iguazú	Bus Station	8:20 AM	Santa Fe, SF	Central Bus Station	First Class	$12	A Bus from Expreso Singer goes from Bus Station, Puerto Iguazú (Argentina) at 12/9/2025 4:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/10/2025 8:20:00 AM. 50 First Class ticket for $12 per person are available. Travel duration is 16h 20m
Rio Uruguay	17h 30m	7:30 AM	Puerto Iguazú	Bus Station	1:00 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/9/2025 7:30:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/10/2025 1:00:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 17h 30m
Rio Uruguay	16h 45m	12:00 PM	Puerto Iguazú	Bus Station	4:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/9/2025 12:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/10/2025 4:45:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 16h 45m
Rio Uruguay	16h 0m	2:00 PM	Puerto Iguazú	Bus Station	6:00 AM	Santa Fe, SF	Central Bus Station	First Class	$84	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/9/2025 2:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/10/2025 6:00:00 AM. 50 First Class ticket for $84 per person are available. Travel duration is 16h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Expreso Singer	16h 20m	4:00 PM	Puerto Iguazú	Bus Station	8:20 AM	Santa Fe, SF	Central Bus Station	First Class	$12	A Bus from Expreso Singer goes from Bus Station, Puerto Iguazú (Argentina) at 12/10/2025 4:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 8:20:00 AM. 50 First Class ticket for $12 per person are available. Travel duration is 16h 20m
Rio Uruguay	17h 30m	7:30 AM	Puerto Iguazú	Bus Station	1:00 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/10/2025 7:30:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 1:00:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 17h 30m
Rio Uruguay	16h 45m	12:00 PM	Puerto Iguazú	Bus Station	4:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/10/2025 12:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 4:45:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 16h 45m
Rio Uruguay	16h 0m	2:00 PM	Puerto Iguazú	Bus Station	6:00 AM	Santa Fe, SF	Central Bus Station	First Class	$84	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/10/2025 2:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 6:00:00 AM. 50 First Class ticket for $84 per person are available. Travel duration is 16h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Expreso Singer	16h 20m	4:00 PM	Puerto Iguazú	Bus Station	8:20 AM	Santa Fe, SF	Central Bus Station	First Class	$12	A Bus from Expreso Singer goes from Bus Station, Puerto Iguazú (Argentina) at 12/11/2025 4:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/12/2025 8:20:00 AM. 50 First Class ticket for $12 per person are available. Travel duration is 16h 20m
Rio Uruguay	17h 30m	7:30 AM	Puerto Iguazú	Bus Station	1:00 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/11/2025 7:30:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/12/2025 1:00:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 17h 30m
Rio Uruguay	16h 45m	12:00 PM	Puerto Iguazú	Bus Station	4:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$77	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/11/2025 12:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/12/2025 4:45:00 AM. 50 Premium Economy ticket for $77 per person are available. Travel duration is 16h 45m
Rio Uruguay	16h 0m	2:00 PM	Puerto Iguazú	Bus Station	6:00 AM	Santa Fe, SF	Central Bus Station	First Class	$84	A Bus from Rio Uruguay goes from Bus Station, Puerto Iguazú (Argentina) at 12/11/2025 2:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/12/2025 6:00:00 AM. 50 First Class ticket for $84 per person are available. Travel duration is 16h 0m

Best Price Offer: The price for the cheapest bus from Puerto Iguazú to Santa Fe, SF is $12 on 11/30/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Puerto Iguazú and Santa Fe, SF

See here how frequent the connections between Puerto Iguazú and Santa Fe, SF are, during different times and days of the week.

Tuesday is the busiest day, with more than 9 daily buses from Puerto Iguazú to Santa Fe, SF. Sunday has instead the fewest connections, with only 8 daily coaches between Puerto Iguazú and Santa Fe, SF.

The busiest time of the day is the Afternoon, with 47 buses from Puerto Iguazú to Santa Fe, SF, while Morning sees the fewest connections between Puerto Iguazú and Santa Fe, SF, with 14 offers.

Facts about the bus from Puerto Iguazú to Santa Fe, SF

Compare all providers like Rio Uruguay and Expreso Singer that travel 8 times every day by bus from Puerto Iguazú to Santa Fe, SF in one click! Book your bus ticket from Puerto Iguazú to Santa Fe, SF starting from $12!

Cheapest Bus	$12
Fastest Bus	16h 0m
Earliest Bus	7:30 AM
Latest Bus	4:00 PM
Daily Bus Routes	8 Ø
Distance	557.2 miles
Bus Companies	Rio Uruguay and Expreso Singer

Cheapest bus connections from Puerto Iguazú to Santa Fe, SF

Every day, 8 buses from 2 bus companies leave Puerto Iguazú for Santa Fe, SF: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$12

Saturday 12/06

$12

Sunday 12/07

$77

Monday 12/08

$77

Tuesday 12/09

$12

Wednesday 12/10

$12

Thursday 12/11

$12

Friday 12/12

$96

Saturday 12/13

$12

Sunday 12/14

$12

Monday 12/15

$12

Tuesday 12/16

$77

Wednesday 12/17

Thursday 12/18

$68

Friday 12/19

$68

Saturday 12/20

Sunday 12/21

$77

Monday 12/22

$77

Tuesday 12/23

$77

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Puerto Iguazú to Santa Fe, SF

See here on which day and which time of the day you can find the cheapest bus ticket from Puerto Iguazú to Santa Fe, SF, for the next 30 days.

With a price starting from $12, Tuesday is the cheapest day for a bus from Puerto Iguazú to Santa Fe, SF. Sunday instead is the most expensive day with prices starting from $12.

Afternoon is the cheapest day time for bus tickets from Puerto Iguazú to Santa Fe, SF, with $12. Morning is the most expensive time of the day with prices starting from $77.

How to save money travelling from Puerto Iguazú to Santa Fe, SF

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Puerto Iguazú to Santa Fe, SF in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Puerto Iguazú to Santa Fe, SF, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Puerto Iguazú to Santa Fe, SF are also emptier.

All bus stations and stops in Puerto Iguazú and Santa Fe, SF

In the map below, you can see where to find all bus stations in Puerto Iguazú and Santa Fe, SF.

Bus Station

Av. Misiónes 1-99

Grand Crucero Iguazú

Puerto

Central Bus Station

Gral. Manuel Belgrano 2910

Bus Stop

Las Avispas

Córdoba

Service and Comfort on the bus from Puerto Iguazú to Santa Fe, SF

Want to know which seat classes are available on the buses from Puerto Iguazú to Santa Fe, SF? Or which bus companies serve the route Puerto Iguazú to Santa Fe, SF? Below you will find answers to your questions.

FAQs about the Puerto Iguazú to Santa Fe, SF bus

How much does a Puerto Iguazú Santa Fe, SF bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $12 and takes 16h 20m to reach Santa Fe, SF. Compare offers to save money!

How much could I save by comparing buses from Puerto Iguazú to Santa Fe, SF?

This route is offered by 2 companies with a range of ticket prices between $12 and $96. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Fe, SF.

On average, how many connections are available from Puerto Iguazú to Santa Fe, SF each day?

Every day, the Puerto Iguazú to Santa Fe, SF bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Puerto Iguazú to Santa Fe, SF take?

The fastest bus from Puerto Iguazú to Santa Fe, SF is offered by Rio Uruguay and takes 16h 0m. Bus tickets for this connection cost $84. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Puerto Iguazú to Santa Fe, SF?

The earliest bus arriving in Santa Fe, SF from Puerto Iguazú starts at 7:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Puerto Iguazú to Santa Fe, SF?

The latest bus trip departing from Puerto Iguazú for Santa Fe, SF starts at 4:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Puerto Iguazú Santa Fe, SF route?

When traveling by bus from Puerto Iguazú to Santa Fe, SF, passengers can travel with Rio Uruguay and Expreso Singer. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Puerto Iguazú and Santa Fe, SF?

You can check all the direct connections between Puerto Iguazú and Santa Fe, SF by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Rio Uruguay and Expreso Singer.

What can I take with me on the Puerto Iguazú to Santa Fe, SF bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Puerto Iguazú Santa Fe, SF bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Puerto Iguazú Santa Fe, SF bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Puerto Iguazú to Santa Fe, SF on your planned travel date.

Available seat classes which are offered on the bus route Puerto Iguazú to Santa Fe, SF

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Puerto Iguazú and to Santa Fe, SF

Here’s an overview of the most popular bus routes to Puerto Iguazú and to Santa Fe, SF. Simply click on the connection of your choice, and you will find all the details about your bus route!