Bus Mendoza to Santa Fe, SF - Compare all Companies

Compare all timetables for the bus from Mendoza to Santa Fe, SF

Here is a selection of the cheapest bus trips from the schedule from Mendoza to Santa Fe, SF from various bus operators like 20 de Junio, Andesmar or Flecha Bus for the next days.

today

$53

tomorrow

$57

Sunday

$57

Monday

$57

Tuesday

Wednesday

$57

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
20 de Junio	16h 5m	9:00 AM	Mendoza	Bus Station	1:05 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$53	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/5/2025 9:00:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 1:05:00 AM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 16h 5m
20 de Junio	15h 55m	9:30 PM	Mendoza	Bus Station	1:25 PM	Santa Fe, SF	Central Bus Station	Premium Economy	$53	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/5/2025 9:30:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 1:25:00 PM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 15h 55m
Flecha Bus	14h 25m	2:15 PM	Mendoza	Bus Station	4:40 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Bus Station, Mendoza (Argentina) at 12/5/2025 2:15:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 4:40:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 25m
Andesmar	14h 45m	8:00 PM	Mendoza	Bus Station	10:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/5/2025 8:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/6/2025 10:45:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 25m	2:15 PM	Mendoza	Bus Station	4:40 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Bus Station, Mendoza (Argentina) at 12/6/2025 2:15:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 4:40:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 25m
Andesmar	14h 45m	8:00 PM	Mendoza	Bus Station	10:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/6/2025 8:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 10:45:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 45m
20 de Junio	16h 5m	9:00 AM	Mendoza	Bus Station	1:05 AM	Santa Fe, SF	Central Bus Station	First Class	$82	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/6/2025 9:00:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 1:05:00 AM. 50 First Class ticket for $82 per person are available. Travel duration is 16h 5m
20 de Junio	15h 55m	9:30 PM	Mendoza	Bus Station	1:25 PM	Santa Fe, SF	Central Bus Station	First Class	$82	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/6/2025 9:30:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/7/2025 1:25:00 PM. 50 First Class ticket for $82 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Mendoza to Santa Fe, SF via Córdoba, CD, you can save more than $8? You can find the corresponding connections below.
- Plataforma 10
  
  17h 50m
  
  0
  
  11:00 AM
  
  Mendoza
  Bus Station
  
  11:30 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $34
  
  A Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 12/7/2025 11:00:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 12/7/2025 11:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 12h 30m
- Voyenbus
  
  5h 0m
  
  0
  
  11:50 PM
  
  Córdoba, CD
  Bus Station
  
  4:50 AM
  
  Santa Fe, SF
  Central Bus Station
  
  0
  
  Premium Economy
  
  $15
  
  A Bus from Voyenbus goes from Bus Station, Córdoba, CD (Argentina) at 12/7/2025 11:50:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 4:50:00 AM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 0m
Travel time is 3h 25m longer, but you will save $8

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 25m	2:15 PM	Mendoza	Bus Station	4:40 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Bus Station, Mendoza (Argentina) at 12/7/2025 2:15:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 4:40:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 25m
20 de Junio	16h 5m	9:00 AM	Mendoza	Bus Station	1:05 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/7/2025 9:00:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 1:05:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 16h 5m
20 de Junio	15h 55m	9:30 PM	Mendoza	Bus Station	1:25 PM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/7/2025 9:30:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 1:25:00 PM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 15h 55m
Andesmar	14h 45m	8:00 PM	Mendoza	Bus Station	10:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/7/2025 8:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/8/2025 10:45:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 45m

Did you know that if you travel from Mendoza to Santa Fe, SF via Córdoba, CD, you can save more than $11? You can find the corresponding connections below.
- Plataforma 10
  
  17h 50m
  
  0
  
  11:00 AM
  
  Mendoza
  Bus Station
  
  11:30 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $31
  
  A Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 12/8/2025 11:00:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 12/8/2025 11:30:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 12h 30m
- Voyenbus
  
  5h 0m
  
  0
  
  11:50 PM
  
  Córdoba, CD
  Bus Station
  
  4:50 AM
  
  Santa Fe, SF
  Central Bus Station
  
  0
  
  Premium Economy
  
  $15
  
  A Bus from Voyenbus goes from Bus Station, Córdoba, CD (Argentina) at 12/8/2025 11:50:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 4:50:00 AM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 0m
Travel time is 3h 25m longer, but you will save $11

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 25m	2:15 PM	Mendoza	Bus Station	4:40 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Bus Station, Mendoza (Argentina) at 12/8/2025 2:15:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 4:40:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 25m
Andesmar	14h 45m	8:00 PM	Mendoza	Bus Station	10:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/8/2025 8:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 10:45:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 45m
20 de Junio	16h 5m	9:00 AM	Mendoza	Bus Station	1:05 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/8/2025 9:00:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 1:05:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 16h 5m
20 de Junio	15h 55m	9:30 PM	Mendoza	Bus Station	1:25 PM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/8/2025 9:30:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/9/2025 1:25:00 PM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Mendoza to Santa Fe, SF via Córdoba, CD, you can save more than $15? You can find the corresponding connections below.
- Plataforma 10
  
  17h 50m
  
  0
  
  11:00 AM
  
  Mendoza
  Bus Station
  
  11:30 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $27
  
  A Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 12/9/2025 11:00:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 12/9/2025 11:30:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 30m
- Voyenbus
  
  5h 0m
  
  0
  
  11:50 PM
  
  Córdoba, CD
  Bus Station
  
  4:50 AM
  
  Santa Fe, SF
  Central Bus Station
  
  0
  
  Premium Economy
  
  $15
  
  A Bus from Voyenbus goes from Bus Station, Córdoba, CD (Argentina) at 12/9/2025 11:50:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/10/2025 4:50:00 AM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 0m
Travel time is 3h 25m longer, but you will save $15

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flecha Bus	14h 25m	2:15 PM	Mendoza	Bus Station	4:40 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$57	A Bus from Flecha Bus goes from Bus Station, Mendoza (Argentina) at 12/10/2025 2:15:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 4:40:00 AM. 50 Premium Economy ticket for $57 per person are available. Travel duration is 14h 25m
20 de Junio	16h 5m	9:00 AM	Mendoza	Bus Station	1:05 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/10/2025 9:00:00 AM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 1:05:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 16h 5m
20 de Junio	15h 55m	9:30 PM	Mendoza	Bus Station	1:25 PM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from 20 de Junio goes from Bus Station, Mendoza (Argentina) at 12/10/2025 9:30:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 1:25:00 PM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 15h 55m
Andesmar	14h 45m	8:00 PM	Mendoza	Bus Station	10:45 AM	Santa Fe, SF	Central Bus Station	Premium Economy	$66	A Bus from Andesmar goes from Bus Station, Mendoza (Argentina) at 12/10/2025 8:00:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/11/2025 10:45:00 AM. 50 Premium Economy ticket for $66 per person are available. Travel duration is 14h 45m

Did you know that if you travel from Mendoza to Santa Fe, SF via Córdoba, CD, you can save more than $15? You can find the corresponding connections below.
- Plataforma 10
  
  17h 50m
  
  0
  
  11:00 AM
  
  Mendoza
  Bus Station
  
  11:30 PM
  
  Córdoba, CD
  Bus Station
  
  0
  
  Premium Economy
  
  $27
  
  A Bus from Plataforma 10 goes from Bus Station, Mendoza (Argentina) at 12/9/2025 11:00:00 AM to Bus Station, Córdoba, CD (Argentina) arriving at 12/9/2025 11:30:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 30m
- Voyenbus
  
  5h 0m
  
  0
  
  11:50 PM
  
  Córdoba, CD
  Bus Station
  
  4:50 AM
  
  Santa Fe, SF
  Central Bus Station
  
  0
  
  Premium Economy
  
  $15
  
  A Bus from Voyenbus goes from Bus Station, Córdoba, CD (Argentina) at 12/9/2025 11:50:00 PM to Central Bus Station, Santa Fe, SF (Argentina) arriving at 12/10/2025 4:50:00 AM. 50 Premium Economy ticket for $15 per person are available. Travel duration is 5h 0m
Travel time is 3h 25m longer, but you will save $15

Best Price Offer: The price for the cheapest bus from Mendoza to Santa Fe, SF is $33 on 12/13/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Mendoza and Santa Fe, SF

See here how frequent the connections between Mendoza and Santa Fe, SF are, during different times and days of the week.

Friday is the busiest day, with more than 15 daily buses from Mendoza to Santa Fe, SF. Wednesday has instead the fewest connections, with only 8 daily coaches between Mendoza and Santa Fe, SF.

The busiest time of the day is the Evening, with 32 buses from Mendoza to Santa Fe, SF, while Afternoon sees the fewest connections between Mendoza and Santa Fe, SF, with 7 offers.

Facts about the bus from Mendoza to Santa Fe, SF

Compare all providers like 20 de Junio, Andesmar and Flecha Bus that travel 10 times every day by bus from Mendoza to Santa Fe, SF in one click! Book your bus ticket from Mendoza to Santa Fe, SF starting from $33!

Cheapest Bus	$33
Fastest Bus	14h 25m
Earliest Bus	9:00 AM
Latest Bus	9:30 PM
Daily Bus Routes	10 Ø
Distance	484.2 miles
Bus Companies	20 de Junio, Andesmar and Flecha Bus

Cheapest bus connections from Mendoza to Santa Fe, SF

Every day, 10 buses from 3 bus companies leave Mendoza for Santa Fe, SF: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$53

Saturday 12/06

$55

Sunday 12/07

$46

Monday 12/08

$46

Tuesday 12/09

Wednesday 12/10

$57

Thursday 12/11

Friday 12/12

$55

Saturday 12/13

$33

Sunday 12/14

$55

Monday 12/15

$46

Tuesday 12/16

Wednesday 12/17

$50

Thursday 12/18

Friday 12/19

$55

Saturday 12/20

$52

Sunday 12/21

$57

Monday 12/22

$53

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

$53

Friday 12/26

$57

Saturday 12/27

The cheapest time to travel from Mendoza to Santa Fe, SF

See here on which day and which time of the day you can find the cheapest bus ticket from Mendoza to Santa Fe, SF, for the next 30 days.

With a price starting from $33, Saturday is the cheapest day for a bus from Mendoza to Santa Fe, SF. Friday instead is the most expensive day with prices starting from $53.

Morning is the cheapest day time for bus tickets from Mendoza to Santa Fe, SF, with $53. Afternoon is the most expensive time of the day with prices starting from $57.

How to save money travelling from Mendoza to Santa Fe, SF

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mendoza to Santa Fe, SF in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mendoza to Santa Fe, SF, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mendoza to Santa Fe, SF are also emptier.

All bus stations and stops in Mendoza and Santa Fe, SF

In the map below, you can see where to find all bus stations in Mendoza and Santa Fe, SF.

Bus Station

Juan B. Alberdi s/n

Hotel Internacional

Av. Sarmiento 720

Hotel NH Cordillera

1324 1324

Casa Juri

Centro Informacion Turistica

de Julio 9

Central Bus Station

Gral. Manuel Belgrano 2910

Bus Stop

Las Avispas

Córdoba

Service and Comfort on the bus from Mendoza to Santa Fe, SF

Want to know which seat classes are available on the buses from Mendoza to Santa Fe, SF? Or which bus companies serve the route Mendoza to Santa Fe, SF? Below you will find answers to your questions.

FAQs about the Mendoza to Santa Fe, SF bus

How much does a Mendoza Santa Fe, SF bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $33 and takes 16h 5m to reach Santa Fe, SF. Compare offers to save money!

How much could I save by comparing buses from Mendoza to Santa Fe, SF?

This route is offered by 3 companies with a range of ticket prices between $33 and $89. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Fe, SF.

On average, how many connections are available from Mendoza to Santa Fe, SF each day?

Every day, the Mendoza to Santa Fe, SF bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mendoza to Santa Fe, SF take?

The fastest bus from Mendoza to Santa Fe, SF is offered by Flecha Bus and takes 14h 25m. Bus tickets for this connection cost $57. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mendoza to Santa Fe, SF?

The earliest bus arriving in Santa Fe, SF from Mendoza starts at 9:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mendoza to Santa Fe, SF?

The latest bus trip departing from Mendoza for Santa Fe, SF starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mendoza Santa Fe, SF route?

When traveling by bus from Mendoza to Santa Fe, SF, passengers can travel with 20 de Junio, Andesmar and Flecha Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mendoza and Santa Fe, SF?

You can check all the direct connections between Mendoza and Santa Fe, SF by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: 20 de Junio, Andesmar and Flecha Bus.

What can I take with me on the Mendoza to Santa Fe, SF bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mendoza Santa Fe, SF bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mendoza Santa Fe, SF bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mendoza to Santa Fe, SF on your planned travel date.

Available seat classes which are offered on the bus route Mendoza to Santa Fe, SF

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Mendoza and to Santa Fe, SF

Here’s an overview of the most popular bus routes to Mendoza and to Santa Fe, SF. Simply click on the connection of your choice, and you will find all the details about your bus route!