Bus Santo Tome, CR to Puerto Iguazú: Compare prices and save money

Compare all timetables for the bus from Santo Tome, CR to Puerto Iguazú

Here is a selection of the cheapest bus trips from the schedule from Santo Tome, CR to Puerto Iguazú from various bus operators like 20 de Junio or Rio Uruguay for the next days.

today

tomorrow

$43

Monday

Tuesday

$43

Wednesday

Thursday

Friday

$43

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Rio Uruguay	8h 0m	5:30 AM	Santo Tome, CR	Bus Stop	1:30 PM	Puerto Iguazú	Bus Station		First Class	$43	A Bus from Rio Uruguay goes from Bus Stop, Santo Tome, CR (Argentina) at 3/22/2026 5:30:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/22/2026 1:30:00 PM. 50 First Class ticket for $43 per person are available. Travel duration is 8h 0m
	20 de Junio	7h 15m	5:00 AM	Santo Tome, CR	Bus Stop	12:15 PM	Puerto Iguazú	Bus Station		Premium Economy	$55	A Bus from 20 de Junio goes from Bus Stop, Santo Tome, CR (Argentina) at 3/22/2026 5:00:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/22/2026 12:15:00 PM. 50 Premium Economy ticket for $55 per person are available. Travel duration is 7h 15m

Did you know that if you travel from Santo Tome, CR to Puerto Iguazú via Posadas, AR, you can save more than $7? You can find the corresponding connections below.
- Rio Uruguay
  
  8h 55m
  
  0
  
  3:00 AM
  
  Santo Tome, CR
  Bus Stop
  
  5:30 AM
  
  Posadas, AR
  Bus Station
  
  0
  
  Premium Economy
  
  $13
  
  A Bus from Rio Uruguay goes from Bus Stop, Santo Tome, CR (Argentina) at 3/22/2026 3:00:00 AM to Bus Station, Posadas, AR (Argentina) arriving at 3/22/2026 5:30:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 2h 30m
- Rio Uruguay
  
  4h 40m
  
  0
  
  7:15 AM
  
  Posadas, AR
  Bus Station
  
  11:55 AM
  
  Puerto Iguazú
  Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Rio Uruguay goes from Bus Station, Posadas, AR (Argentina) at 3/22/2026 7:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/22/2026 11:55:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 4h 40m
Travel time is 1h 40m longer, but you will save $7

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Rio Uruguay	8h 0m	5:30 AM	Santo Tome, CR	Bus Stop	1:30 PM	Puerto Iguazú	Bus Station		First Class	$43	A Bus from Rio Uruguay goes from Bus Stop, Santo Tome, CR (Argentina) at 3/24/2026 5:30:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/24/2026 1:30:00 PM. 50 First Class ticket for $43 per person are available. Travel duration is 8h 0m
	20 de Junio	7h 15m	5:00 AM	Santo Tome, CR	Bus Stop	12:15 PM	Puerto Iguazú	Bus Station		Premium Economy	$55	A Bus from 20 de Junio goes from Bus Stop, Santo Tome, CR (Argentina) at 3/24/2026 5:00:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/24/2026 12:15:00 PM. 50 Premium Economy ticket for $55 per person are available. Travel duration is 7h 15m

Did you know that if you travel from Santo Tome, CR to Puerto Iguazú via Posadas, AR, you can save more than $11? You can find the corresponding connections below.
- Flecha Bus
  
  7h 40m
  
  0
  
  8:20 AM
  
  Santo Tome, CR
  Bus Stop
  
  10:35 AM
  
  Posadas, AR
  Bus Station
  
  0
  
  Premium Economy
  
  $10
  
  A Bus from Flecha Bus goes from Bus Stop, Santo Tome, CR (Argentina) at 3/24/2026 8:20:00 AM to Bus Station, Posadas, AR (Argentina) arriving at 3/24/2026 10:35:00 AM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 2h 15m
- Rio Uruguay
  
  5h 0m
  
  0
  
  11:00 AM
  
  Posadas, AR
  Bus Station
  
  4:00 PM
  
  Puerto Iguazú
  Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Rio Uruguay goes from Bus Station, Posadas, AR (Argentina) at 3/24/2026 11:00:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/24/2026 4:00:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 0m
Travel time is 0h 25m longer, but you will save $11

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Rio Uruguay	8h 0m	5:30 AM	Santo Tome, CR	Bus Stop	1:30 PM	Puerto Iguazú	Bus Station		First Class	$43	A Bus from Rio Uruguay goes from Bus Stop, Santo Tome, CR (Argentina) at 3/27/2026 5:30:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/27/2026 1:30:00 PM. 50 First Class ticket for $43 per person are available. Travel duration is 8h 0m
	20 de Junio	7h 15m	5:00 AM	Santo Tome, CR	Bus Stop	12:15 PM	Puerto Iguazú	Bus Station		Premium Economy	$55	A Bus from 20 de Junio goes from Bus Stop, Santo Tome, CR (Argentina) at 3/27/2026 5:00:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/27/2026 12:15:00 PM. 50 Premium Economy ticket for $55 per person are available. Travel duration is 7h 15m

Did you know that if you travel from Santo Tome, CR to Puerto Iguazú via Posadas, AR, you can save more than $11? You can find the corresponding connections below.
- Flecha Bus
  
  7h 40m
  
  0
  
  8:20 AM
  
  Santo Tome, CR
  Bus Stop
  
  10:35 AM
  
  Posadas, AR
  Bus Station
  
  0
  
  Premium Economy
  
  $10
  
  A Bus from Flecha Bus goes from Bus Stop, Santo Tome, CR (Argentina) at 3/24/2026 8:20:00 AM to Bus Station, Posadas, AR (Argentina) arriving at 3/24/2026 10:35:00 AM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 2h 15m
- Rio Uruguay
  
  5h 0m
  
  0
  
  11:00 AM
  
  Posadas, AR
  Bus Station
  
  4:00 PM
  
  Puerto Iguazú
  Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Rio Uruguay goes from Bus Station, Posadas, AR (Argentina) at 3/24/2026 11:00:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 3/24/2026 4:00:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 0m
Travel time is 0h 25m longer, but you will save $11

Best Price Offer: The price for the cheapest bus from Santo Tome, CR to Puerto Iguazú is $39 on 4/6/2026. Flexible travelers save on ticket prices.

Facts about the bus from Santo Tome, CR to Puerto Iguazú

Compare all providers like 20 de Junio and Rio Uruguay that travel 3 times every day by bus from Santo Tome, CR to Puerto Iguazú in one click! Book your bus ticket from Santo Tome, CR to Puerto Iguazú starting from $39!

Cheapest Bus	$39
Fastest Bus	7h 15m
Earliest Bus	5:00 AM
Latest Bus	5:30 AM
Daily Bus Routes	3 Ø
Distance	223.3 miles
Bus Companies	20 de Junio and Rio Uruguay

Cheapest bus connections from Santo Tome, CR to Puerto Iguazú

Every day, 3 buses from 2 bus companies leave Santo Tome, CR for Puerto Iguazú: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/15

Monday 03/16

Tuesday 03/17

Wednesday 03/18

Thursday 03/19

Friday 03/20

Saturday 03/21

Sunday 03/22

$43

Monday 03/23

Tuesday 03/24

$43

Wednesday 03/25

Thursday 03/26

Friday 03/27

$43

Saturday 03/28

Sunday 03/29

Monday 03/30

Tuesday 03/31

Wednesday 04/01

Thursday 04/02

Friday 04/03

$43

Saturday 04/04

Sunday 04/05

$43

Monday 04/06

$39

Tuesday 04/07

Wednesday 04/08

$39

Thursday 04/09

$39

Friday 04/10

$39

Saturday 04/11

How to save money travelling from Santo Tome, CR to Puerto Iguazú

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santo Tome, CR to Puerto Iguazú in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santo Tome, CR to Puerto Iguazú, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santo Tome, CR to Puerto Iguazú are also emptier.

All bus stations and stops in Santo Tome, CR and Puerto Iguazú

In the map below, you can see where to find all bus stations in Santo Tome, CR and Puerto Iguazú.

Bus Stop

Bus Station

Av. Misiónes 1-99

Grand Crucero Iguazú

Puerto

Taxi y remis Junior Turismo Bus Stop

Service and Comfort on the bus from Santo Tome, CR to Puerto Iguazú

Want to know which seat classes are available on the buses from Santo Tome, CR to Puerto Iguazú? Or which bus companies serve the route Santo Tome, CR to Puerto Iguazú? Below you will find answers to your questions.

FAQs about the Santo Tome, CR to Puerto Iguazú bus

How much does a Santo Tome, CR Puerto Iguazú bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $39 and takes 8h 0m to reach Puerto Iguazú. Compare offers to save money!

How much could I save by comparing buses from Santo Tome, CR to Puerto Iguazú?

This route is offered by 2 companies with a range of ticket prices between $39 and $65. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Puerto Iguazú.

On average, how many connections are available from Santo Tome, CR to Puerto Iguazú each day?

Every day, the Santo Tome, CR to Puerto Iguazú bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santo Tome, CR to Puerto Iguazú take?

The fastest bus from Santo Tome, CR to Puerto Iguazú is offered by 20 de Junio and takes 7h 15m. Bus tickets for this connection cost $65. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santo Tome, CR to Puerto Iguazú?

The earliest bus arriving in Puerto Iguazú from Santo Tome, CR starts at 5:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santo Tome, CR to Puerto Iguazú?

The latest bus trip departing from Santo Tome, CR for Puerto Iguazú starts at 5:30 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santo Tome, CR Puerto Iguazú route?

When traveling by bus from Santo Tome, CR to Puerto Iguazú, passengers can travel with 20 de Junio and Rio Uruguay. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santo Tome, CR and Puerto Iguazú?

You can check all the direct connections between Santo Tome, CR and Puerto Iguazú by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: 20 de Junio and Rio Uruguay.

What can I take with me on the Santo Tome, CR to Puerto Iguazú bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santo Tome, CR Puerto Iguazú bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santo Tome, CR Puerto Iguazú bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santo Tome, CR to Puerto Iguazú on your planned travel date.

How does CheckMyBus find the best bus deals from Santo Tome, CR to Puerto Iguazú?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Santo Tome, CR and Puerto Iguazú. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santo Tome, CR to Puerto Iguazú?

Prices and availability for 3 trips between Santo Tome, CR and Puerto Iguazú change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santo Tome, CR to Puerto Iguazú

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santo Tome, CR and to Puerto Iguazú

Here’s an overview of the most popular bus routes to Santo Tome, CR and to Puerto Iguazú. Simply click on the connection of your choice, and you will find all the details about your bus route!