Bus Santa Fe, SF to Puerto Iguazú: Compare prices and save money

Compare all timetables for the bus from Santa Fe, SF to Puerto Iguazú

Here is a selection of the cheapest bus trips from the schedule from Santa Fe, SF to Puerto Iguazú from various bus operators like Rio Uruguay or 20 de Junio for the next days.

today

$86

tomorrow

$68

Wednesday

$68

Thursday

Friday

$68

Saturday

$78

Sunday

$68

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Rio Uruguay	15h 55m	4:45 PM	Santa Fe, SF	Central Bus Station	8:40 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/10/2026 4:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/11/2026 8:40:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 15h 55m
Rio Uruguay	14h 25m	8:45 PM	Santa Fe, SF	Central Bus Station	11:10 AM	Puerto Iguazú	Bus Station	First Class	$93	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/10/2026 8:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/11/2026 11:10:00 AM. 50 First Class ticket for $93 per person are available. Travel duration is 14h 25m
Rio Uruguay	17h 0m	10:15 PM	Santa Fe, SF	Central Bus Station	3:15 PM	Puerto Iguazú	Bus Station	First Class	$93	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/10/2026 10:15:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/11/2026 3:15:00 PM. 50 First Class ticket for $93 per person are available. Travel duration is 17h 0m

Did you know that if you travel from Santa Fe, SF to Puerto Iguazú via Paso de los Libres, CR, you can save more than $23? You can find the corresponding connections below.
- Rio Uruguay
  
  16h 15m
  
  0
  
  8:45 PM
  
  Santa Fe, SF
  Central Bus Station
  
  2:30 AM
  
  Paso de los Libres, CR
  Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/11/2026 8:45:00 PM to Bus Station, Paso de los Libres, CR (Argentina) arriving at 8/12/2026 2:30:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 45m
- 20 de Junio
  
  9h 10m
  
  0
  
  3:50 AM
  
  Paso de los Libres, CR
  Bus Station
  
  1:00 PM
  
  Puerto Iguazú
  Bus Station
  
  0
  
  Premium Economy
  
  $40
  
  A Bus from 20 de Junio goes from Bus Station, Paso de los Libres, CR (Argentina) at 8/12/2026 3:50:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/12/2026 1:00:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 9h 10m
Travel time is 1h 50m longer, but you will save $23

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
20 de Junio	16h 45m	1:15 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Puerto Iguazú	Bus Station	Premium Economy	$68	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/11/2026 1:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/11/2026 6:00:00 PM. 50 Premium Economy ticket for $68 per person are available. Travel duration is 16h 45m
Rio Uruguay	17h 6m	12:15 AM	Santa Fe, SF	Central Bus Station	5:21 PM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/11/2026 12:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/11/2026 5:21:00 PM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 17h 6m
Rio Uruguay	15h 55m	4:45 PM	Santa Fe, SF	Central Bus Station	8:40 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/11/2026 4:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/12/2026 8:40:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 15h 55m
Rio Uruguay	14h 25m	8:45 PM	Santa Fe, SF	Central Bus Station	11:10 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/11/2026 8:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/12/2026 11:10:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 14h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
20 de Junio	16h 45m	1:15 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Puerto Iguazú	Bus Station	Premium Economy	$68	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/12/2026 1:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/12/2026 6:00:00 PM. 50 Premium Economy ticket for $68 per person are available. Travel duration is 16h 45m
Rio Uruguay	17h 0m	10:15 PM	Santa Fe, SF	Central Bus Station	3:15 PM	Puerto Iguazú	Bus Station	First Class	$74	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/12/2026 10:15:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/13/2026 3:15:00 PM. 50 First Class ticket for $74 per person are available. Travel duration is 17h 0m
Rio Uruguay	17h 6m	12:15 AM	Santa Fe, SF	Central Bus Station	5:21 PM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/12/2026 12:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/12/2026 5:21:00 PM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 17h 6m
Rio Uruguay	15h 55m	4:45 PM	Santa Fe, SF	Central Bus Station	8:40 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/12/2026 4:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/13/2026 8:40:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 15h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
20 de Junio	16h 45m	1:15 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Puerto Iguazú	Bus Station	Premium Economy	$68	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/14/2026 1:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/14/2026 6:00:00 PM. 50 Premium Economy ticket for $68 per person are available. Travel duration is 16h 45m
Rio Uruguay	14h 25m	8:45 PM	Santa Fe, SF	Central Bus Station	11:10 AM	Puerto Iguazú	Bus Station	First Class	$74	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/14/2026 8:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/15/2026 11:10:00 AM. 50 First Class ticket for $74 per person are available. Travel duration is 14h 25m
Rio Uruguay	17h 0m	10:15 PM	Santa Fe, SF	Central Bus Station	3:15 PM	Puerto Iguazú	Bus Station	First Class	$74	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/14/2026 10:15:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/15/2026 3:15:00 PM. 50 First Class ticket for $74 per person are available. Travel duration is 17h 0m
Rio Uruguay	17h 6m	12:15 AM	Santa Fe, SF	Central Bus Station	5:21 PM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/14/2026 12:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/14/2026 5:21:00 PM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 17h 6m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
20 de Junio	16h 45m	1:15 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Puerto Iguazú	Bus Station	Premium Economy	$78	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/15/2026 1:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/15/2026 6:00:00 PM. 50 Premium Economy ticket for $78 per person are available. Travel duration is 16h 45m
Rio Uruguay	17h 6m	12:15 AM	Santa Fe, SF	Central Bus Station	5:21 PM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/15/2026 12:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/15/2026 5:21:00 PM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 17h 6m
Rio Uruguay	15h 55m	4:45 PM	Santa Fe, SF	Central Bus Station	8:40 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/15/2026 4:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/16/2026 8:40:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 15h 55m
Rio Uruguay	14h 25m	8:45 PM	Santa Fe, SF	Central Bus Station	11:10 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/15/2026 8:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/16/2026 11:10:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 14h 25m

Did you know that if you travel from Santa Fe, SF to Puerto Iguazú via Paso de los Libres, CR, you can save more than $15? You can find the corresponding connections below.
- Rio Uruguay
  
  16h 15m
  
  0
  
  8:45 PM
  
  Santa Fe, SF
  Central Bus Station
  
  2:30 AM
  
  Paso de los Libres, CR
  Bus Station
  
  0
  
  Premium Economy
  
  $23
  
  A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/11/2026 8:45:00 PM to Bus Station, Paso de los Libres, CR (Argentina) arriving at 8/12/2026 2:30:00 AM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 5h 45m
- 20 de Junio
  
  9h 10m
  
  0
  
  3:50 AM
  
  Paso de los Libres, CR
  Bus Station
  
  1:00 PM
  
  Puerto Iguazú
  Bus Station
  
  0
  
  Premium Economy
  
  $40
  
  A Bus from 20 de Junio goes from Bus Station, Paso de los Libres, CR (Argentina) at 8/12/2026 3:50:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/12/2026 1:00:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 9h 10m
Travel time is 1h 50m longer, but you will save $15

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
20 de Junio	16h 45m	1:15 AM	Santa Fe, SF	Central Bus Station	6:00 PM	Puerto Iguazú	Bus Station	Premium Economy	$68	A Bus from 20 de Junio goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/16/2026 1:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/16/2026 6:00:00 PM. 50 Premium Economy ticket for $68 per person are available. Travel duration is 16h 45m
Rio Uruguay	17h 6m	12:15 AM	Santa Fe, SF	Central Bus Station	5:21 PM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/16/2026 12:15:00 AM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/16/2026 5:21:00 PM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 17h 6m
Rio Uruguay	15h 55m	4:45 PM	Santa Fe, SF	Central Bus Station	8:40 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/16/2026 4:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/17/2026 8:40:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 15h 55m
Rio Uruguay	14h 25m	8:45 PM	Santa Fe, SF	Central Bus Station	11:10 AM	Puerto Iguazú	Bus Station	Premium Economy	$86	A Bus from Rio Uruguay goes from Central Bus Station, Santa Fe, SF (Argentina) at 8/16/2026 8:45:00 PM to Bus Station, Puerto Iguazú (Argentina) arriving at 8/17/2026 11:10:00 AM. 50 Premium Economy ticket for $86 per person are available. Travel duration is 14h 25m

Best Price Offer: The price for the cheapest bus from Santa Fe, SF to Puerto Iguazú is $68 on 8/9/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santa Fe, SF and Puerto Iguazú

See here how frequent the connections between Santa Fe, SF and Puerto Iguazú are, during different times and days of the week.

Sunday is the busiest day, with more than 20 daily buses from Santa Fe, SF to Puerto Iguazú. Monday has instead the fewest connections, with only 4 daily coaches between Santa Fe, SF and Puerto Iguazú.

The busiest time of the day is the Night, with 42 buses from Santa Fe, SF to Puerto Iguazú, while Afternoon sees the fewest connections between Santa Fe, SF and Puerto Iguazú, with 18 offers.

Facts about the bus from Santa Fe, SF to Puerto Iguazú

Compare all providers like Rio Uruguay and 20 de Junio that travel 14 times every day by bus from Santa Fe, SF to Puerto Iguazú in one click! Book your bus ticket from Santa Fe, SF to Puerto Iguazú starting from $68!

Cheapest Bus	$68
Fastest Bus	14h 25m
Earliest Bus	4:45 PM
Latest Bus	10:15 PM
Daily Bus Routes	14 Ø
Distance	557.2 miles
Bus Companies	Rio Uruguay and 20 de Junio

Cheapest bus connections from Santa Fe, SF to Puerto Iguazú

Every day, 14 buses from 2 bus companies leave Santa Fe, SF for Puerto Iguazú: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/10/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/09

Monday 08/10

$68

Tuesday 08/11

$68

Wednesday 08/12

$68

Thursday 08/13

Friday 08/14

$68

Saturday 08/15

$74

Sunday 08/16

$68

Monday 08/17

$68

Tuesday 08/18

$68

Wednesday 08/19

$68

Thursday 08/20

$68

Friday 08/21

$68

Saturday 08/22

$68

Sunday 08/23

Monday 08/24

$68

Tuesday 08/25

$68

Wednesday 08/26

$68

Thursday 08/27

$68

Friday 08/28

$68

Saturday 08/29

$68

Sunday 08/30

$68

Monday 08/31

Tuesday 09/01

$68

Wednesday 09/02

$68

Thursday 09/03

$68

Friday 09/04

$68

Saturday 09/05

The cheapest time to travel from Santa Fe, SF to Puerto Iguazú

See here on which day and which time of the day you can find the cheapest bus ticket from Santa Fe, SF to Puerto Iguazú, for the next 30 days.

With a price starting from $68, Sunday is the cheapest day for a bus from Santa Fe, SF to Puerto Iguazú. Monday instead is the most expensive day with prices starting from $68.

Night is the cheapest day time for bus tickets from Santa Fe, SF to Puerto Iguazú, with $68. Afternoon is the most expensive time of the day with prices starting from $86.

How to save money travelling from Santa Fe, SF to Puerto Iguazú

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Fe, SF to Puerto Iguazú in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Fe, SF to Puerto Iguazú, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Fe, SF to Puerto Iguazú are also emptier.

All bus stations and stops in Santa Fe, SF and Puerto Iguazú

In the map below, you can see where to find all bus stations in Santa Fe, SF and Puerto Iguazú.

Central Bus Station

Gral. Manuel Belgrano 2910

Bus Stop

Las Avispas

Córdoba

Bus Station

Av. Misiónes 1-99

Grand Crucero Iguazú

Taxi y remis Junior Turismo Bus Stop

Puerto

Service and Comfort on the bus from Santa Fe, SF to Puerto Iguazú

Want to know which seat classes are available on the buses from Santa Fe, SF to Puerto Iguazú? Or which bus companies serve the route Santa Fe, SF to Puerto Iguazú? Below you will find answers to your questions.

FAQs about the Santa Fe, SF to Puerto Iguazú bus

How much does a Santa Fe, SF Puerto Iguazú bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $68 and takes 16h 45m to reach Puerto Iguazú. Compare offers to save money!

How much could I save by comparing buses from Santa Fe, SF to Puerto Iguazú?

This route is offered by 2 companies with a range of ticket prices between $68 and $117. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Puerto Iguazú.

On average, how many connections are available from Santa Fe, SF to Puerto Iguazú each day?

Every day, the Santa Fe, SF to Puerto Iguazú bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Fe, SF to Puerto Iguazú take?

The fastest bus from Santa Fe, SF to Puerto Iguazú is offered by Rio Uruguay and takes 14h 25m. Bus tickets for this connection cost $93. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Fe, SF to Puerto Iguazú?

The earliest bus arriving in Puerto Iguazú from Santa Fe, SF starts at 4:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Fe, SF to Puerto Iguazú?

The latest bus trip departing from Santa Fe, SF for Puerto Iguazú starts at 10:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Fe, SF Puerto Iguazú route?

When traveling by bus from Santa Fe, SF to Puerto Iguazú, passengers can travel with Rio Uruguay and 20 de Junio. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Fe, SF and Puerto Iguazú?

You can check all the direct connections between Santa Fe, SF and Puerto Iguazú by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Rio Uruguay and 20 de Junio.

What can I take with me on the Santa Fe, SF to Puerto Iguazú bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Fe, SF Puerto Iguazú bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Fe, SF Puerto Iguazú bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Fe, SF to Puerto Iguazú on your planned travel date.

How does CheckMyBus find the best bus deals from Santa Fe, SF to Puerto Iguazú?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Santa Fe, SF and Puerto Iguazú. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santa Fe, SF to Puerto Iguazú?

Prices and availability for 14 trips between Santa Fe, SF and Puerto Iguazú change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santa Fe, SF to Puerto Iguazú

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santa Fe, SF and to Puerto Iguazú

Here’s an overview of the most popular bus routes to Santa Fe, SF and to Puerto Iguazú. Simply click on the connection of your choice, and you will find all the details about your bus route!