What is the best way to travel from Mestre to Florence?
Looking for a trip? Compare all the available Buses and Trains for the journey to Florence from Mestre. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Florence from Mestre?
You can get to Florence with just $8 by taking a Bus from Itabus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/5/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 25m
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FlixBus5h 41m011:59 PMVenice AirportVenice Airport5:40 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 11:59:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 5:40:00 AM. 50 Economy ticket for $18 per person are available. Travel duration is 5h 41m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0BasicA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 3:10:00 AM. 50 Basic ticket for $18 per person are available. Travel duration is 4h 50m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/5/2026 6:05:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 35m
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Trenitalia4h 44m05:26 PMMestreVenice - Mestre Ospedale Train Station10:10 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/5/2026 10:10:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 44m
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Trenitalia3h 56m05:26 PMMestreVenice - Mestre Ospedale Train Station9:22 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/5/2026 9:22:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 3h 56m
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Trenitalia4h 1m01:26 PMMestreVenice - Mestre Ospedale Train Station5:27 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 1:26:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/5/2026 5:27:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 4h 1m
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Trenitalia3h 49m012:26 PMMestreVenice - Mestre Ospedale Train Station4:15 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 12:26:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/5/2026 4:15:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 3h 49m
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Trenitalia3h 27m02:58 PMMestreVenice - Mestre Ospedale Train Station6:25 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 2:58:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/5/2026 6:25:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 3h 27m
Cheapest Buses Thursday
Cheapest Trains Thursday
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 25m
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FlixBus4h 20m011:20 AMVenice AirportVenice Airport3:40 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 11:20:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 3:40:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 20m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 6:05:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 35m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 3:10:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 50m
Cheapest Buses Friday
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 4:20:00 PM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 4h 25m
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Itabus4h 20m012:30 AMVenice AirportVenice Airport4:50 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 12:30:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 4:50:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 20m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 35m
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FlixBus4h 20m011:20 AMVenice AirportVenice Airport3:40 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 11:20:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 3:40:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 4h 20m
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Trenitalia3h 27m02:58 PMMestreVenice - Mestre Ospedale Train Station6:25 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 2:58:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/7/2026 6:25:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 3h 27m
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Trenitalia4h 44m05:26 PMMestreVenice - Mestre Ospedale Train Station10:10 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/7/2026 10:10:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 44m
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Trenitalia3h 29m08:58 AMMestreVenice - Mestre Ospedale Train Station12:27 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 8:58:00 AM to Rifredi Train Station, Florence (Italy) arriving at 2/7/2026 12:27:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 3h 29m
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Trenitalia3h 56m05:26 PMMestreVenice - Mestre Ospedale Train Station9:22 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/7/2026 9:22:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 3h 56m
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Trenitalia4h 52m05:20 AMMestreVenice - Mestre Ospedale Train Station10:12 AMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 5:20:00 AM to Rifredi Train Station, Florence (Italy) arriving at 2/7/2026 10:12:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 4h 52m
Cheapest Buses Saturday
Cheapest Trains Saturday
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/8/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 25m
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FlixBus4h 20m011:20 AMVenice AirportVenice Airport3:40 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 11:20:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/8/2026 3:40:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 4h 20m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/9/2026 3:10:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 4h 50m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/8/2026 6:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 35m
Cheapest Buses Sunday
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/9/2026 4:20:00 PM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 4h 25m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 3:10:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 50m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/9/2026 6:05:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 4h 35m
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FlixBus4h 40m08:25 PMVenice AirportVenice Airport1:05 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 8:25:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 1:05:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 4h 40m
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FlixBus5h 5m08:25 PMVenice AirportVenice Airport1:30 AMFlorencePiazzale Montelungo Bus Stop0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 8:25:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 2/10/2026 1:30:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 5m
Cheapest Buses Monday
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/11/2026 3:10:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 4h 50m
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 25m
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Itabus4h 20m012:30 AMVenice AirportVenice Airport4:50 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 12:30:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 4:50:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 20m
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FlixBus5h 5m08:25 PMVenice AirportVenice Airport1:30 AMFlorencePiazzale Montelungo Bus Stop0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 8:25:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 2/11/2026 1:30:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 5h 5m
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FlixBus4h 40m08:25 PMVenice AirportVenice Airport1:05 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 8:25:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/11/2026 1:05:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 4h 40m
Cheapest Buses Tuesday
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/11/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/11/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 25m
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FlixBus5h 5m08:25 PMVenice AirportVenice Airport1:30 AMFlorencePiazzale Montelungo Bus Stop0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/11/2026 8:25:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 2/12/2026 1:30:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 5m
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FlixBus4h 40m08:25 PMVenice AirportVenice Airport1:05 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/11/2026 8:25:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/12/2026 1:05:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 40m
Cheapest Buses Wednesday
What are the fastest trips from Mestre to Florence?
You can get to Florence from Mestre in just 3h 27m with a Train from Trenitalia. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Trenitalia3h 27m02:58 PMMestreVenice - Mestre Ospedale Train Station6:25 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 2:58:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/5/2026 6:25:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 3h 27m
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Trenitalia3h 49m012:26 PMMestreVenice - Mestre Ospedale Train Station4:15 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 12:26:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/5/2026 4:15:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 3h 49m
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Trenitalia3h 56m05:26 PMMestreVenice - Mestre Ospedale Train Station9:22 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/5/2026 9:22:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 3h 56m
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Trenitalia4h 1m01:26 PMMestreVenice - Mestre Ospedale Train Station5:27 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 1:26:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/5/2026 5:27:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 4h 1m
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Trenitalia4h 44m05:26 PMMestreVenice - Mestre Ospedale Train Station10:10 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/5/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/5/2026 10:10:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 44m
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/5/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 25m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/5/2026 6:05:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 35m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0BasicA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 3:10:00 AM. 50 Basic ticket for $18 per person are available. Travel duration is 4h 50m
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FlixBus5h 41m011:59 PMVenice AirportVenice Airport5:40 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/5/2026 11:59:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 5:40:00 AM. 50 Economy ticket for $18 per person are available. Travel duration is 5h 41m
Fastest Trains Thursday
Fastest Buses Thursday
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FlixBus4h 20m011:20 AMVenice AirportVenice Airport3:40 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 11:20:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 3:40:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 20m
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 25m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/6/2026 6:05:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 4h 35m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/6/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 3:10:00 AM. 50 Premium Economy ticket for $22 per person are available. Travel duration is 4h 50m
Fastest Buses Friday
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Trenitalia3h 27m02:58 PMMestreVenice - Mestre Ospedale Train Station6:25 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 2:58:00 PM to Rifredi Train Station, Florence (Italy) arriving at 2/7/2026 6:25:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 3h 27m
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Trenitalia3h 29m08:58 AMMestreVenice - Mestre Ospedale Train Station12:27 PMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 8:58:00 AM to Rifredi Train Station, Florence (Italy) arriving at 2/7/2026 12:27:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 3h 29m
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Trenitalia3h 56m05:26 PMMestreVenice - Mestre Ospedale Train Station9:22 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/7/2026 9:22:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 3h 56m
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Trenitalia4h 44m05:26 PMMestreVenice - Mestre Ospedale Train Station10:10 PMFlorenceSanta Maria Novella Central Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 5:26:00 PM to Santa Maria Novella Central Station, Florence (Italy) arriving at 2/7/2026 10:10:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 44m
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Trenitalia4h 52m05:20 AMMestreVenice - Mestre Ospedale Train Station10:12 AMFlorenceRifredi Train Station0EconomyA Train from Trenitalia goes from Venice - Mestre Ospedale Train Station, Mestre (Italy) at 2/7/2026 5:20:00 AM to Rifredi Train Station, Florence (Italy) arriving at 2/7/2026 10:12:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 4h 52m
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Itabus4h 20m012:30 AMVenice AirportVenice Airport4:50 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 12:30:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 4:50:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 20m
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FlixBus4h 20m011:20 AMVenice AirportVenice Airport3:40 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 11:20:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 3:40:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 4h 20m
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 4:20:00 PM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 4h 25m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/7/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 35m
Fastest Trains Saturday
Fastest Buses Saturday
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FlixBus4h 20m011:20 AMVenice AirportVenice Airport3:40 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 11:20:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/8/2026 3:40:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 4h 20m
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/8/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 25m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/8/2026 6:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 35m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/8/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/9/2026 3:10:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 4h 50m
Fastest Buses Sunday
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/9/2026 4:20:00 PM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 4h 25m
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FlixBus4h 35m01:30 PMVenice AirportVenice Airport6:05 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 1:30:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/9/2026 6:05:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 4h 35m
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FlixBus4h 40m08:25 PMVenice AirportVenice Airport1:05 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 8:25:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 1:05:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 4h 40m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 3:10:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 50m
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FlixBus5h 5m08:25 PMVenice AirportVenice Airport1:30 AMFlorencePiazzale Montelungo Bus Stop0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/9/2026 8:25:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 2/10/2026 1:30:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 5m
Fastest Buses Monday
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Itabus4h 20m012:30 AMVenice AirportVenice Airport4:50 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 12:30:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 4:50:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 20m
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/10/2026 4:20:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 25m
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FlixBus4h 40m08:25 PMVenice AirportVenice Airport1:05 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 8:25:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/11/2026 1:05:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 4h 40m
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Itabus4h 50m010:20 PMVenice AirportVenice Airport3:10 AMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 10:20:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/11/2026 3:10:00 AM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 4h 50m
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FlixBus5h 5m08:25 PMVenice AirportVenice Airport1:30 AMFlorencePiazzale Montelungo Bus Stop0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/10/2026 8:25:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 2/11/2026 1:30:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 5h 5m
Fastest Buses Tuesday
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Itabus4h 25m011:55 AMVenice AirportVenice Airport4:20 PMFlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Itabus goes from Venice Airport, Venice Airport (Italy) at 2/11/2026 11:55:00 AM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/11/2026 4:20:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 25m
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FlixBus4h 40m08:25 PMVenice AirportVenice Airport1:05 AMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/11/2026 8:25:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 2/12/2026 1:05:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 40m
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FlixBus5h 5m08:25 PMVenice AirportVenice Airport1:30 AMFlorencePiazzale Montelungo Bus Stop0EconomyA Bus from FlixBus goes from Venice Airport, Venice Airport (Italy) at 2/11/2026 8:25:00 PM to Piazzale Montelungo Bus Stop, Florence (Italy) arriving at 2/12/2026 1:30:00 AM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 5m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Mestre to Florence
What are the most popular stations in Mestre and Florence?
In Mestre, you will usually depart from Venice - Mestre Ospedale Train Station or Centro Bus Stop, while in Florence you will be arriving at Santa Maria Novella Central Station, Villa Costanza Bus Station or Piazzale Montelungo Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Florence from Mestre? With 6 connections between 1 Bus and Train operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mestre and Florence, you can pay as low as $8 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Trenitalia: you will get to Florence in just 3h 27m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mestre and Florence are Itabus, FlixBus and Trenitalia, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mestre and Florence is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Zelarino or to Scandicci, and look at flights from Venice Airport, and landing at Florence Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mestre to Florence?
The most popular companies between Mestre and Florence, are Itabus, FlixBus and Trenitalia. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus and FlixBus
Train companies: Trenitalia
All you need to know when you travel from Mestre to Florence
Check all information on comfort and services on all modes of transports from Mestre to Florence. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mestre to Florence
How can I reach Florence from Mestre?
Every day, there are on average 6 connections between Bus and Train, with which you can get to Florence from Mestre.
How far is Florence from Mestre?
The distance between Mestre and Florence is 128.6 miles.
What is the most ecofriendly mode of transport between Mestre and Florence?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 6 kgs of CO2, a train 7 kgs, a car 35 kgs, and a flight 51 kgs.
What is the cheapest mode of transport from Mestre to Florence?
You can get to Florence with just $8 by taking a Bus from Itabus.
What is the fastest way to get from Mestre to Florence?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Florence in just 3h 27m with a Train from Trenitalia.
More routes to Mestre and to Florence
Looking for more options? Here you can see the most popular routes to Mestre and to Florence. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mestre
- Rome to Mestre
- Trips to Florence
- Bari to Florence
- Bologna Airport to Florence
- Bologna to Florence
- Brescia to Florence
- Cassino to Florence
- Cosenza to Florence
- Foligno to Florence
- Genoa to Florence
- La Spezia to Florence
- Marseille to Florence
- Milan to Florence
- Naples to Florence
- Padua to Florence
- Perugia to Florence
- Pisa Airport to Florence
- Pisa to Florence
- Reggio Calabria to Florence
- Rimini to Florence
- Rome Fiumicino Airport to Florence
- Rome to Florence
- Sala Consilina to Florence
- Salerno to Florence
- Siena to Florence
- Venice to Florence
