What is the best way to travel from Portland, OR to San Diego?
Looking for a trip? Compare all the available Buses and Flights for the journey to San Diego from Portland, OR. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach San Diego from Portland, OR?
You can get to San Diego with just $111 by taking a Flight from Frontier Airlines, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Alaska Airlines2h 33m02:44 PMPortland, OR AirportPortland, OR Airport5:17 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:44:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 5:17:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 33m05:30 PMPortland, OR AirportPortland, OR Airport8:03 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 5:30:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 8:03:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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Skyscanner6h 39m02:50 PMPortland, OR AirportPortland, OR Airport9:29 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:50:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 9:29:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 6h 39m
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Skyscanner4h 16m02:56 PMPortland, OR AirportPortland, OR Airport7:12 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:56:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 7:12:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 4h 16m
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United Airlines7h 47m02:45 PMPortland, OR AirportPortland, OR Airport10:32 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:45:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 10:32:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 7h 47m
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Volaris9h 14m011:18 PMPortland, OR AirportPortland, OR Airport8:32 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 11:18:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/21/2025 8:32:00 AM. 50 Economy ticket for $883 per person are available. Travel duration is 9h 14m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/21/2025 11:50:00 PM. 50 Economy ticket for $418 per person are available. Travel duration is 27h 50m
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FlixBus44h 25m08:00 PMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 4:25:00 PM. 50 Economy ticket for $418 per person are available. Travel duration is 44h 25m
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FlixBus50h 15m08:00 PMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $420 per person are available. Travel duration is 50h 15m
Cheapest Flights Saturday
Cheapest Buses Saturday
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Alaska Airlines2h 37m07:03 AMPortland, OR AirportPortland, OR Airport9:40 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 7:03:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 9:40:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 37m
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Alaska Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 11:07:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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Frontier Airlines6h 28m012:47 PMPortland, OR AirportPortland, OR Airport7:15 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 12:47:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 7:15:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 6h 28m
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Frontier Airlines22h 19m02:19 PMPortland, OR AirportPortland, OR Airport12:38 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 2:19:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/22/2025 12:38:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 22h 19m
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United Airlines5h 32m07:30 AMPortland, OR AirportPortland, OR Airport1:02 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 7:30:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 1:02:00 PM. 50 Economy ticket for $275 per person are available. Travel duration is 5h 32m
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Alaska Airlines9h 18m010:30 AMPortland, OR AirportPortland, OR Airport7:48 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/21/2025 7:48:00 PM. 50 Economy ticket for $548 per person are available. Travel duration is 9h 18m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 11:50:00 PM. 50 Economy ticket for $259 per person are available. Travel duration is 27h 50m
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Greyhound US44h 15m02:00 AMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 44h 15m
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Greyhound US38h 25m02:00 AMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 4:25:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 38h 25m
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FlixBus50h 15m08:00 PMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/23/2025 10:15:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 50h 15m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 44h 15m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Greyhound US38h 25m02:00 AMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/22/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/23/2025 4:25:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m02:00 AMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/22/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/23/2025 10:15:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 44h 15m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/22/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/23/2025 11:50:00 PM. 50 Economy ticket for $258 per person are available. Travel duration is 27h 50m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/22/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/23/2025 10:15:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 44h 15m
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FlixBus27h 50m08:00 PMPortland, ORUnion Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/22/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/23/2025 11:50:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 27h 50m
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Frontier Airlines13h 12m08:45 PMPortland, OR AirportPortland, OR Airport9:57 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 8:45:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 9:57:00 AM. 50 Economy ticket for $256 per person are available. Travel duration is 13h 12m
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Alaska Airlines5h 37m07:01 AMPortland, OR AirportPortland, OR Airport12:38 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 7:01:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/22/2025 12:38:00 PM. 50 Economy ticket for $301 per person are available. Travel duration is 5h 37m
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Skyscanner4h 44m07:05 AMPortland, OR AirportPortland, OR Airport11:49 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 7:05:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/22/2025 11:49:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 4h 44m
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Hawaiian Airlines11h 3m09:42 PMPortland, OR AirportPortland, OR Airport8:45 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Hawaiian Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 9:42:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 8:45:00 AM. 50 Economy ticket for $330 per person are available. Travel duration is 11h 3m
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United Airlines5h 32m07:30 AMPortland, OR AirportPortland, OR Airport1:02 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 7:30:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/22/2025 1:02:00 PM. 50 Economy ticket for $332 per person are available. Travel duration is 5h 32m
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Delta Air Lines11h 40m05:30 AMPortland, OR AirportPortland, OR Airport5:10 PMTijuana AirportTijuana Airport0EconomyA Flight from Delta Air Lines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 5:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/22/2025 5:10:00 PM. 50 Economy ticket for $419 per person are available. Travel duration is 11h 40m
Cheapest Buses Monday
Cheapest Flights Monday
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Frontier Airlines21h 42m02:29 PMPortland, OR AirportPortland, OR Airport12:11 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 2:29:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/24/2025 12:11:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 21h 42m
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Frontier Airlines6h 28m012:47 PMPortland, OR AirportPortland, OR Airport7:15 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 12:47:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 7:15:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 6h 28m
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Alaska Airlines2h 37m07:03 AMPortland, OR AirportPortland, OR Airport9:40 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 7:03:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 9:40:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 37m
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Alaska Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 11:07:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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United Airlines8h 34m09:00 AMPortland, OR AirportPortland, OR Airport5:34 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 9:00:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 5:34:00 PM. 50 Economy ticket for $275 per person are available. Travel duration is 8h 34m
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Alaska Airlines9h 28m010:30 AMPortland, OR AirportPortland, OR Airport7:58 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/23/2025 7:58:00 PM. 50 Economy ticket for $543 per person are available. Travel duration is 9h 28m
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FlixBus28h 25m08:00 PMPortland, ORUnion Bus Station12:25 AMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 8:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/25/2025 12:25:00 AM. 50 Economy ticket for $207 per person are available. Travel duration is 28h 25m
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Greyhound US34h 20m02:00 AMPortland, ORUnion Bus Station12:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/24/2025 12:20:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 34h 20m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/24/2025 10:15:00 PM. 50 Economy ticket for $363 per person are available. Travel duration is 44h 15m
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FlixBus27h 50m08:00 PMPortland, ORUnion Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/24/2025 11:50:00 PM. 50 Economy ticket for $372 per person are available. Travel duration is 27h 50m
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Greyhound US38h 25m02:00 AMPortland, ORUnion Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/24/2025 4:25:00 PM. 50 Economy ticket for $373 per person are available. Travel duration is 38h 25m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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FlixBus28h 25m08:00 PMPortland, ORUnion Bus Station12:25 AMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 8:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/26/2025 12:25:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 28h 25m
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Greyhound US34h 20m02:00 AMPortland, ORUnion Bus Station12:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/25/2025 12:20:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 34h 20m
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FlixBus44h 25m08:00 PMPortland, ORUnion Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 4:25:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 44h 25m
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FlixBus43h 55m08:00 PMPortland, ORUnion Bus Station3:55 PMSan DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 8:00:00 PM to La Jolla Village, San Diego (USA) arriving at 12/26/2025 3:55:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 43h 55m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/25/2025 10:15:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 44h 15m
Cheapest Buses Wednesday
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Frontier Airlines11h 12m012:47 PMPortland, OR AirportPortland, OR Airport11:59 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 12:47:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 11:59:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 11h 12m
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Frontier Airlines6h 28m012:47 PMPortland, OR AirportPortland, OR Airport7:15 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 12:47:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 7:15:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 6h 28m
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Skyscanner4h 44m07:05 AMPortland, OR AirportPortland, OR Airport11:49 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 7:05:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 11:49:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 4h 44m
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Alaska Airlines2h 36m010:30 AMPortland, OR AirportPortland, OR Airport1:06 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 10:30:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 1:06:00 PM. 50 Economy ticket for $265 per person are available. Travel duration is 2h 36m
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Alaska Airlines2h 33m02:44 PMPortland, OR AirportPortland, OR Airport5:17 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 2:44:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 5:17:00 PM. 50 Economy ticket for $265 per person are available. Travel duration is 2h 33m
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Delta Air Lines17h 28m05:30 AMPortland, OR AirportPortland, OR Airport10:58 PMTijuana AirportTijuana Airport0EconomyA Flight from Delta Air Lines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 5:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/25/2025 10:58:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 17h 28m
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Greyhound US38h 25m02:00 AMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 4:25:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 38h 25m
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FlixBus44h 25m08:00 PMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/27/2025 4:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 44h 25m
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Greyhound US44h 15m02:00 AMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/26/2025 10:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 44h 15m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 11:50:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 27h 50m
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FlixBus50h 15m08:00 PMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/27/2025 10:15:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 50h 15m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Frontier Airlines12h 2m08:45 PMPortland, OR AirportPortland, OR Airport8:47 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 8:45:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/27/2025 8:47:00 AM. 50 Economy ticket for $262 per person are available. Travel duration is 12h 2m
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Alaska Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/26/2025 11:07:00 PM. 50 Economy ticket for $328 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 33m09:34 PMPortland, OR AirportPortland, OR Airport12:07 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 9:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/27/2025 12:07:00 AM. 50 Economy ticket for $328 per person are available. Travel duration is 2h 33m
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Hawaiian Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Hawaiian Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/26/2025 11:07:00 PM. 50 Economy ticket for $336 per person are available. Travel duration is 2h 33m
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Hawaiian Airlines2h 33m09:34 PMPortland, OR AirportPortland, OR Airport12:07 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Hawaiian Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 9:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/27/2025 12:07:00 AM. 50 Economy ticket for $336 per person are available. Travel duration is 2h 33m
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Hawaiian Airlines28h 2m010:49 AMPortland, OR AirportPortland, OR Airport2:51 PMTijuana AirportTijuana Airport0EconomyA Flight from Hawaiian Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 10:49:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/27/2025 2:51:00 PM. 50 Economy ticket for $598 per person are available. Travel duration is 28h 2m
Cheapest Flights Friday
What are the fastest trips from Portland, OR to San Diego?
You can get to San Diego from Portland, OR in just 2h 33m with a Flight from Alaska Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Alaska Airlines2h 33m02:44 PMPortland, OR AirportPortland, OR Airport5:17 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:44:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 5:17:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 33m05:30 PMPortland, OR AirportPortland, OR Airport8:03 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 5:30:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 8:03:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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Skyscanner4h 16m02:56 PMPortland, OR AirportPortland, OR Airport7:12 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:56:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 7:12:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 4h 16m
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Skyscanner6h 39m02:50 PMPortland, OR AirportPortland, OR Airport9:29 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:50:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 9:29:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 6h 39m
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United Airlines7h 47m02:45 PMPortland, OR AirportPortland, OR Airport10:32 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 2:45:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/20/2025 10:32:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 7h 47m
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Volaris9h 14m011:18 PMPortland, OR AirportPortland, OR Airport8:32 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/20/2025 11:18:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/21/2025 8:32:00 AM. 50 Economy ticket for $883 per person are available. Travel duration is 9h 14m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/21/2025 11:50:00 PM. 50 Economy ticket for $418 per person are available. Travel duration is 27h 50m
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FlixBus44h 25m08:00 PMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 4:25:00 PM. 50 Economy ticket for $418 per person are available. Travel duration is 44h 25m
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FlixBus50h 15m08:00 PMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $420 per person are available. Travel duration is 50h 15m
Fastest Flights Saturday
Fastest Buses Saturday
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Alaska Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 11:07:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 37m07:03 AMPortland, OR AirportPortland, OR Airport9:40 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 7:03:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 9:40:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 37m
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United Airlines5h 32m07:30 AMPortland, OR AirportPortland, OR Airport1:02 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 7:30:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 1:02:00 PM. 50 Economy ticket for $275 per person are available. Travel duration is 5h 32m
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Frontier Airlines6h 28m012:47 PMPortland, OR AirportPortland, OR Airport7:15 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 12:47:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/21/2025 7:15:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 6h 28m
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Alaska Airlines9h 15m010:30 AMPortland, OR AirportPortland, OR Airport7:45 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/21/2025 7:45:00 PM. 50 Economy ticket for $595 per person are available. Travel duration is 9h 15m
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Alaska Airlines9h 18m010:30 AMPortland, OR AirportPortland, OR Airport7:48 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/21/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/21/2025 7:48:00 PM. 50 Economy ticket for $548 per person are available. Travel duration is 9h 18m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 11:50:00 PM. 50 Economy ticket for $259 per person are available. Travel duration is 27h 50m
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Greyhound US38h 25m02:00 AMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 4:25:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m02:00 AMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 44h 15m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 44h 15m
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FlixBus50h 15m08:00 PMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/23/2025 10:15:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 50h 15m
Fastest Flights Sunday
Fastest Buses Sunday
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Skyscanner4h 44m07:05 AMPortland, OR AirportPortland, OR Airport11:49 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 7:05:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/22/2025 11:49:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 4h 44m
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United Airlines5h 32m07:30 AMPortland, OR AirportPortland, OR Airport1:02 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 7:30:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/22/2025 1:02:00 PM. 50 Economy ticket for $332 per person are available. Travel duration is 5h 32m
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Alaska Airlines5h 37m07:01 AMPortland, OR AirportPortland, OR Airport12:38 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 7:01:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/22/2025 12:38:00 PM. 50 Economy ticket for $301 per person are available. Travel duration is 5h 37m
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Alaska Airlines9h 15m010:30 AMPortland, OR AirportPortland, OR Airport7:45 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/22/2025 7:45:00 PM. 50 Economy ticket for $557 per person are available. Travel duration is 9h 15m
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Alaska Airlines9h 18m010:30 AMPortland, OR AirportPortland, OR Airport7:48 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/22/2025 7:48:00 PM. 50 Economy ticket for $532 per person are available. Travel duration is 9h 18m
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Hawaiian Airlines11h 3m09:42 PMPortland, OR AirportPortland, OR Airport8:45 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Hawaiian Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/22/2025 9:42:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 8:45:00 AM. 50 Economy ticket for $330 per person are available. Travel duration is 11h 3m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/22/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/23/2025 11:50:00 PM. 50 Economy ticket for $258 per person are available. Travel duration is 27h 50m
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FlixBus27h 50m08:00 PMPortland, ORUnion Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/22/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/23/2025 11:50:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 27h 50m
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Greyhound US38h 25m02:00 AMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/22/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/23/2025 4:25:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m02:00 AMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/22/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/23/2025 10:15:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 44h 15m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/22/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/23/2025 10:15:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 44h 15m
Fastest Flights Monday
Fastest Buses Monday
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Alaska Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 11:07:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 37m07:03 AMPortland, OR AirportPortland, OR Airport9:40 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 7:03:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 9:40:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 2h 37m
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Frontier Airlines6h 28m012:47 PMPortland, OR AirportPortland, OR Airport7:15 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 12:47:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 7:15:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 6h 28m
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United Airlines8h 34m09:00 AMPortland, OR AirportPortland, OR Airport5:34 PMSan Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 9:00:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/23/2025 5:34:00 PM. 50 Economy ticket for $275 per person are available. Travel duration is 8h 34m
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Volaris9h 14m011:18 PMPortland, OR AirportPortland, OR Airport8:32 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 11:18:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/24/2025 8:32:00 AM. 50 Economy ticket for $772 per person are available. Travel duration is 9h 14m
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Alaska Airlines9h 15m010:30 AMPortland, OR AirportPortland, OR Airport7:45 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/23/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/23/2025 7:45:00 PM. 50 Economy ticket for $567 per person are available. Travel duration is 9h 15m
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FlixBus27h 50m08:00 PMPortland, ORUnion Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/24/2025 11:50:00 PM. 50 Economy ticket for $372 per person are available. Travel duration is 27h 50m
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FlixBus28h 25m08:00 PMPortland, ORUnion Bus Station12:25 AMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 8:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/25/2025 12:25:00 AM. 50 Economy ticket for $207 per person are available. Travel duration is 28h 25m
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Greyhound US34h 20m02:00 AMPortland, ORUnion Bus Station12:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/24/2025 12:20:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 34h 20m
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Greyhound US38h 25m02:00 AMPortland, ORUnion Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/24/2025 4:25:00 PM. 50 Economy ticket for $373 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/24/2025 10:15:00 PM. 50 Economy ticket for $363 per person are available. Travel duration is 44h 15m
Fastest Flights Tuesday
Fastest Buses Tuesday
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FlixBus28h 25m08:00 PMPortland, ORUnion Bus Station12:25 AMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 8:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/26/2025 12:25:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 28h 25m
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Greyhound US34h 20m02:00 AMPortland, ORUnion Bus Station12:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/25/2025 12:20:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 34h 20m
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FlixBus43h 55m08:00 PMPortland, ORUnion Bus Station3:55 PMSan DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 8:00:00 PM to La Jolla Village, San Diego (USA) arriving at 12/26/2025 3:55:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 43h 55m
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Greyhound US44h 15m02:00 AMPortland, ORUnion Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/25/2025 10:15:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 44h 15m
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FlixBus44h 25m08:00 PMPortland, ORUnion Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/24/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 4:25:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 44h 25m
Fastest Buses Wednesday
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Alaska Airlines2h 33m02:44 PMPortland, OR AirportPortland, OR Airport5:17 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 2:44:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 5:17:00 PM. 50 Economy ticket for $265 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 36m010:30 AMPortland, OR AirportPortland, OR Airport1:06 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 10:30:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 1:06:00 PM. 50 Economy ticket for $265 per person are available. Travel duration is 2h 36m
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Skyscanner4h 44m07:05 AMPortland, OR AirportPortland, OR Airport11:49 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 7:05:00 AM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 11:49:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 4h 44m
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Frontier Airlines6h 28m012:47 PMPortland, OR AirportPortland, OR Airport7:15 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 12:47:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/25/2025 7:15:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 6h 28m
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Volaris9h 14m011:18 PMPortland, OR AirportPortland, OR Airport8:32 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 11:18:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/26/2025 8:32:00 AM. 50 Economy ticket for $415 per person are available. Travel duration is 9h 14m
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Alaska Airlines9h 15m010:30 AMPortland, OR AirportPortland, OR Airport7:45 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/25/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/25/2025 7:45:00 PM. 50 Economy ticket for $435 per person are available. Travel duration is 9h 15m
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FlixBus27h 50m08:00 PMPortland, ORGreyhound Bus Station11:50 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 11:50:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 27h 50m
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Greyhound US38h 25m02:00 AMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/26/2025 4:25:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m02:00 AMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/26/2025 10:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 44h 15m
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FlixBus44h 25m08:00 PMPortland, ORGreyhound Bus Station4:25 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/27/2025 4:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 44h 25m
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FlixBus50h 15m08:00 PMPortland, ORGreyhound Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/25/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/27/2025 10:15:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 50h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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Alaska Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/26/2025 11:07:00 PM. 50 Economy ticket for $328 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 33m09:34 PMPortland, OR AirportPortland, OR Airport12:07 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 9:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/27/2025 12:07:00 AM. 50 Economy ticket for $328 per person are available. Travel duration is 2h 33m
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Hawaiian Airlines2h 33m08:34 PMPortland, OR AirportPortland, OR Airport11:07 PMSan Diego AirportSan Diego Airport0EconomyA Flight from Hawaiian Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 8:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/26/2025 11:07:00 PM. 50 Economy ticket for $336 per person are available. Travel duration is 2h 33m
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Hawaiian Airlines2h 33m09:34 PMPortland, OR AirportPortland, OR Airport12:07 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Hawaiian Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 9:34:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/27/2025 12:07:00 AM. 50 Economy ticket for $336 per person are available. Travel duration is 2h 33m
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Alaska Airlines9h 18m010:30 AMPortland, OR AirportPortland, OR Airport7:48 PMTijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 10:30:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 12/26/2025 7:48:00 PM. 50 Economy ticket for $843 per person are available. Travel duration is 9h 18m
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Frontier Airlines12h 2m08:45 PMPortland, OR AirportPortland, OR Airport8:47 AMSan Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 12/26/2025 8:45:00 PM to San Diego Airport, San Diego Airport (USA) arriving at 12/27/2025 8:47:00 AM. 50 Economy ticket for $262 per person are available. Travel duration is 12h 2m
Fastest Flights Friday
Here you will find all operators and timetables for a
Bus from Portland, OR to San Diego
What are the most popular stations in Portland, OR and San Diego?
In Portland, OR, you will usually depart from Greyhound Bus Station, SE 102nd & Washington Bus Stop or Union Bus Station, while in San Diego you will be arriving at San Ysidro Transit Center, University Av & Bancroft St Bus Stop or Old Town Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from Portland, OR? With 11 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Portland, OR and San Diego, you can pay as low as $111 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Alaska Airlines: you will get to San Diego in just 2h 33m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Portland, OR and San Diego are Alaska Airlines, FlixBus and Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Portland, OR and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from West Haven-Sylvan, OR or to San Diego Airport, and look at flights from Portland, OR Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Portland, OR to San Diego?
The most popular companies between Portland, OR and San Diego, are Alaska Airlines, FlixBus and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and Greyhound US
Airlines: Alaska Airlines, Frontier Airlines, Volaris and 4 more.
All you need to know when you travel from Portland, OR to San Diego
Check all information on comfort and services on all modes of transports from Portland, OR to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Portland, OR to San Diego
How can I reach San Diego from Portland, OR?
Every day, there are on average 11 connections between Bus and Flight, with which you can get to San Diego from Portland, OR.
How far is San Diego from Portland, OR?
The distance between Portland, OR and San Diego is 932.4 miles.
What is the most ecofriendly mode of transport between Portland, OR and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 41 kgs of CO2, a train 53 kgs, a car 255 kgs, and a flight 369 kgs.
What is the cheapest mode of transport from Portland, OR to San Diego?
You can get to San Diego with just $111 by taking a Flight from Frontier Airlines.
What is the fastest way to get from Portland, OR to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 2h 33m with a Flight from Alaska Airlines.
More routes to Portland, OR and to San Diego
Looking for more options? Here you can see the most popular routes to Portland, OR and to San Diego. Simply click on a connection, and you’ll find all the details about the route!
