What is the best way to travel from Rome to Brno?
Looking for a trip? Compare all the available Carpool and Buses for the journey to Brno from Rome. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Brno from Rome?
You can get to Brno with just $73 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 3/26/2026 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 12:25:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 25h 40m
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/26/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 8:25:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 19h 40m
-
FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/26/2026 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 12:25:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 23h 20m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/26/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 8:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 5m
-
FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/26/2026 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 12:25:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 19h 20m
Cheapest Buses Thursday
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/27/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 8:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 19h 40m
-
FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/27/2026 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 12:25:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 20m
-
FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 3/27/2026 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 12:25:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 25h 40m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/27/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 8:25:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 20h 5m
-
FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/27/2026 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 8:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 55m
Cheapest Buses Friday
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station9:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/28/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 9:25:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 19h 40m
-
FlixBus24h 0m01:05 PMRomeAnagnina Bus Station2:05 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/28/2026 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 2:05:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 24h 0m
-
FlixBus19h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/28/2026 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 8:00:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 19h 55m
-
FlixBus20h 55m05:05 PMRomeTiburtina Bus Station3:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/28/2026 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 3:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 20h 55m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station9:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/28/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 9:25:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 5m
Cheapest Buses Saturday
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/29/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 8:25:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 19h 40m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/29/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 8:25:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 5m
-
FlixBus26h 25m010:55 PMRomeTiburtina Bus Station1:20 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/29/2026 10:55:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/31/2026 1:20:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 26h 25m
-
FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 3/29/2026 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 12:25:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 25h 40m
-
FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/29/2026 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 12:25:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 23h 20m
Cheapest Buses Sunday
What are the fastest trips from Rome to Brno?
You can get to Brno from Rome in just 19h 20m with a Bus from FlixBus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/26/2026 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 12:25:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 19h 20m
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/26/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 8:25:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 19h 40m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/26/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 8:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 5m
-
FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/26/2026 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 12:25:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 23h 20m
-
FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 3/26/2026 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 3/27/2026 12:25:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 25h 40m
Fastest Buses Thursday
-
FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/27/2026 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 12:25:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 20m
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/27/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 8:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 19h 40m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/27/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 8:25:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 20h 5m
-
FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/27/2026 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 8:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 20h 55m
-
FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 3/27/2026 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 3/28/2026 12:25:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 25h 40m
Fastest Buses Friday
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station9:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/28/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 9:25:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 19h 40m
-
FlixBus19h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/28/2026 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 8:00:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 19h 55m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station9:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/28/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 9:25:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 5m
-
FlixBus20h 55m05:05 PMRomeTiburtina Bus Station3:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/28/2026 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 3:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 20h 55m
-
FlixBus24h 0m01:05 PMRomeAnagnina Bus Station2:05 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/28/2026 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/29/2026 2:05:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 24h 0m
Fastest Buses Saturday
-
FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/29/2026 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 8:25:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 19h 40m
-
FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/29/2026 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 8:25:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 5m
-
FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 3/29/2026 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 12:25:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 23h 20m
-
FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 3/29/2026 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 3/30/2026 12:25:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 25h 40m
-
FlixBus26h 25m010:55 PMRomeTiburtina Bus Station1:20 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 3/29/2026 10:55:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 3/31/2026 1:20:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 26h 25m
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Rome to Brno
What are the most popular stations in Rome and Brno?
In Rome, you will usually depart from Termini Bus Station, Ostiense Train Station or Termini Central Station, while in Brno you will be arriving at Hotel Grand, Židenice or Train station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brno from Rome? With 5 connections between 1 Carpool and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Brno, you can pay as low as $73 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Brno in just 19h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Brno are FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Brno is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Moravany, and look at flights from Rome Ciampino Airport, and landing at Brno Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Brno?
The most popular companies between Rome and Brno, are FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
All you need to know when you travel from Rome to Brno
Check all information on comfort and services on all modes of transports from Rome to Brno. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Brno
How can I reach Brno from Rome?
Every day, there are on average 5 connections between Carpool and Bus, with which you can get to Brno from Rome.
How far is Brno from Rome?
The distance between Rome and Brno is 541.7 miles.
What is the most ecofriendly mode of transport between Rome and Brno?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 148 kgs, and a flight 214 kgs.
What is the cheapest mode of transport from Rome to Brno?
You can get to Brno with just $73 by taking a Bus from FlixBus.
What is the fastest way to get from Rome to Brno?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brno in just 19h 20m with a Bus from FlixBus.
More routes to Rome and to Brno
Looking for more options? Here you can see the most popular routes to Rome and to Brno. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Caserta to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lanciano to Rome
- Lecce to Rome
- Marseille to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Perugia to Rome
- Pescara to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Brno
- Bratislava to Brno
- Budapest to Brno
- Florence to Brno
- Györ to Brno
- Jihlava to Brno
- Katowice Airport to Brno
- Krakow John Paul II Airport to Brno
- Lucenec to Brno
- Olomouc to Brno
- Ostrava to Brno
- Pilsen to Brno
- Prague Airport to Brno
- Prague to Brno
- Split to Brno
- Trnava to Brno
- Uherský Brod to Brno
- Vienna Airport to Brno
- Vienna to Brno
- Vsetín to Brno
- Zlín to Brno
- Zurich to Brno
- Zvolen to Brno
