What is the best way to travel from Rome to Brno?
Looking for a trip? Compare all the available Buses, Flights and Carpool for the journey to Brno from Rome. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brno from Rome?
You can get to Brno with just $84 by taking a Bus from RegioJet, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/18/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 8:25:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 40m
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FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/18/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 12:25:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 23h 20m
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FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/18/2025 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 12:25:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 25h 40m
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/18/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 12:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 19h 20m
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Ryanair10h 50m011:25 AMRome Ciampino AirportRome Ciampino Airport10:15 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/18/2025 11:25:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/18/2025 10:15:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 10h 50m
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LC Perú15h 30m06:45 AMRome Fiumicino AirportRome Fiumicino Airport10:15 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/18/2025 6:45:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/18/2025 10:15:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 15h 30m
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EasyJet Airline11h 20m010:55 AMRome Fiumicino AirportRome Fiumicino Airport10:15 PMBrno AirportBrno Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/18/2025 10:55:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/18/2025 10:15:00 PM. 50 Economy ticket for $250 per person are available. Travel duration is 11h 20m
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Ryanair26h 25m07:45 PMRome Ciampino AirportRome Ciampino Airport10:10 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/18/2025 7:45:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/19/2025 10:10:00 PM. 50 Economy ticket for $290 per person are available. Travel duration is 26h 25m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/19/2025 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 12:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 25h 40m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 8:25:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 19h 40m
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FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 12:25:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 23h 20m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 8:25:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 5m
Cheapest Buses Friday
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FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 12:25:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 25h 40m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/20/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 5:45:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 24h 20m
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 12:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 19h 20m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 8:25:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 20h 5m
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Ryanair28h 35m02:05 PMRome Ciampino AirportRome Ciampino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 2:05:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 28h 35m
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Skyscanner26h 40m04:00 PMRome Ciampino AirportRome Ciampino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 4:00:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 26h 40m
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Ryanair22h 5m08:35 PMRome Ciampino AirportRome Ciampino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 8:35:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 22h 5m
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EasyJet Airline22h 55m07:45 PMRome Fiumicino AirportRome Fiumicino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 7:45:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 22h 55m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/21/2025 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 12:25:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 25h 40m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 5:45:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 24h 20m
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FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 12:25:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 23h 20m
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 12:25:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 19h 20m
Cheapest Buses Sunday
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 8:25:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 19h 40m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 5:45:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 24h 20m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 8:25:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 8:00:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 20h 55m
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Skyscanner26h 55m09:05 AMRome Ciampino AirportRome Ciampino Airport12:00 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/22/2025 9:05:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 12:00:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 26h 55m
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Ryanair25h 50m010:10 AMRome Ciampino AirportRome Ciampino Airport12:00 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/22/2025 10:10:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 12:00:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 25h 50m
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LC Perú16h 40m07:20 PMRome Fiumicino AirportRome Fiumicino Airport12:00 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/22/2025 7:20:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 12:00:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 16h 40m
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Vueling Airlines31h 30m010:35 AMRome Fiumicino AirportRome Fiumicino Airport6:05 PMBrno AirportBrno Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/22/2025 10:35:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 31h 30m
Cheapest Buses Monday
Cheapest Flights Monday
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RegioJet17h 40m01:00 PMRomeTiburtina Bus Station6:40 AMBrnoBenesova Bus Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 12/24/2025 6:40:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 17h 40m
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RegioJet20h 6m01:00 PMRomeTiburtina Bus Station9:06 AMBrnoKrálovo Pole Train Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:00:00 PM to Královo Pole Train Station, Brno (Czech Republic) arriving at 12/24/2025 9:06:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 6m
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FlixBus25h 40m010:45 AMRome Ciampino AirportRome Ciampino Airport12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/23/2025 10:45:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 12/24/2025 12:25:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 25h 40m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/23/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/24/2025 5:45:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 24h 20m
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LC Perú11h 25m06:40 AMRome Fiumicino AirportRome Fiumicino Airport6:05 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/23/2025 6:40:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 11h 25m
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Ryanair20h 50m06:35 PMRome Ciampino AirportRome Ciampino Airport3:25 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/23/2025 6:35:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/24/2025 3:25:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 20h 50m
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Skyscanner19h 5m08:20 PMRome Ciampino AirportRome Ciampino Airport3:25 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/23/2025 8:20:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/24/2025 3:25:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 19h 5m
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Skyscanner23h 55m03:30 PMRome Ciampino AirportRome Ciampino Airport3:25 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/23/2025 3:30:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/24/2025 3:25:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 23h 55m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/25/2025 5:45:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 24h 20m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/25/2025 8:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 20h 5m
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/25/2025 12:25:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 20m
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FlixBus26h 25m010:55 PMRomeTiburtina Bus Station1:20 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 10:55:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/26/2025 1:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 26h 25m
Cheapest Buses Wednesday
What are the fastest trips from Rome to Brno?
You can get to Brno from Rome in just 10h 50m with a Flight from Ryanair. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Ryanair10h 50m011:25 AMRome Ciampino AirportRome Ciampino Airport10:15 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/18/2025 11:25:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/18/2025 10:15:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 10h 50m
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EasyJet Airline11h 20m010:55 AMRome Fiumicino AirportRome Fiumicino Airport10:15 PMBrno AirportBrno Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/18/2025 10:55:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/18/2025 10:15:00 PM. 50 Economy ticket for $250 per person are available. Travel duration is 11h 20m
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LC Perú15h 30m06:45 AMRome Fiumicino AirportRome Fiumicino Airport10:15 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/18/2025 6:45:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/18/2025 10:15:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 15h 30m
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Ryanair26h 25m07:45 PMRome Ciampino AirportRome Ciampino Airport10:10 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/18/2025 7:45:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/19/2025 10:10:00 PM. 50 Economy ticket for $290 per person are available. Travel duration is 26h 25m
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/18/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 12:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 19h 20m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/18/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 8:25:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 40m
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FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/18/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 12:25:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 23h 20m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/18/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/19/2025 5:45:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 24h 20m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 8:25:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 8:25:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 8:00:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 20h 55m
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FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/20/2025 12:25:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 23h 20m
Fastest Buses Friday
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 12:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 19h 20m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 8:25:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 8:00:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 20h 55m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/20/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/21/2025 5:45:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 24h 20m
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Ryanair22h 5m08:35 PMRome Ciampino AirportRome Ciampino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 8:35:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 22h 5m
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EasyJet Airline22h 55m07:45 PMRome Fiumicino AirportRome Fiumicino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 7:45:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 22h 55m
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Skyscanner26h 40m04:00 PMRome Ciampino AirportRome Ciampino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 4:00:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 26h 40m
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Ryanair28h 35m02:05 PMRome Ciampino AirportRome Ciampino Airport6:40 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 2:05:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/21/2025 6:40:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 28h 35m
Fastest Buses Saturday
Fastest Flights Saturday
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 12:25:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 19h 20m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 8:00:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 20h 55m
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FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 12:25:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 23h 20m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/22/2025 5:45:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 24h 20m
Fastest Buses Sunday
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EasyJet Airline15h 5m08:55 PMRome Fiumicino AirportRome Fiumicino Airport12:00 PMBrno AirportBrno Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/22/2025 8:55:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 12:00:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 15h 5m
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LC Perú16h 40m07:20 PMRome Fiumicino AirportRome Fiumicino Airport12:00 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/22/2025 7:20:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 12:00:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 16h 40m
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Ryanair25h 50m010:10 AMRome Ciampino AirportRome Ciampino Airport12:00 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/22/2025 10:10:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 12:00:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 25h 50m
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Skyscanner26h 55m09:05 AMRome Ciampino AirportRome Ciampino Airport12:00 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/22/2025 9:05:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 12:00:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 26h 55m
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FlixBus19h 40m012:45 PMRomeAnagnina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 12:45:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 8:25:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 19h 40m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 8:25:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 20h 5m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 8:00:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 20h 55m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/23/2025 5:45:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 24h 20m
Fastest Flights Monday
Fastest Buses Monday
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LC Perú11h 25m06:40 AMRome Fiumicino AirportRome Fiumicino Airport6:05 PMBrno AirportBrno Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/23/2025 6:40:00 AM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 11h 25m
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Skyscanner19h 5m08:20 PMRome Ciampino AirportRome Ciampino Airport3:25 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/23/2025 8:20:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/24/2025 3:25:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 19h 5m
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Ryanair20h 50m06:35 PMRome Ciampino AirportRome Ciampino Airport3:25 PMBrno AirportBrno Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/23/2025 6:35:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/24/2025 3:25:00 PM. 50 Economy ticket for $215 per person are available. Travel duration is 20h 50m
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Skyscanner23h 55m03:30 PMRome Ciampino AirportRome Ciampino Airport3:25 PMBrno AirportBrno Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/23/2025 3:30:00 PM to Brno Airport, Brno Airport (Czech Republic) arriving at 12/24/2025 3:25:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 23h 55m
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RegioJet17h 40m01:00 PMRomeTiburtina Bus Station6:40 AMBrnoBenesova Bus Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 12/24/2025 6:40:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 17h 40m
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RegioJet20h 6m01:00 PMRomeTiburtina Bus Station9:06 AMBrnoKrálovo Pole Train Station0EconomyA Bus from RegioJet goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:00:00 PM to Královo Pole Train Station, Brno (Czech Republic) arriving at 12/24/2025 9:06:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 6m
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FlixBus20h 55m011:05 PMRomeTiburtina Bus Station8:00 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 11:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/24/2025 8:00:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 20h 55m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/23/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/24/2025 5:45:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 24h 20m
Fastest Flights Tuesday
Fastest Buses Tuesday
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FlixBus19h 20m05:05 PMRomeTiburtina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 5:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/25/2025 12:25:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 20m
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FlixBus20h 5m012:20 PMRomeTiburtina Bus Station8:25 AMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 12:20:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/25/2025 8:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 20h 5m
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FlixBus23h 20m01:05 PMRomeAnagnina Bus Station12:25 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 1:05:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/25/2025 12:25:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 23h 20m
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FlixBus24h 20m05:25 PMRomeAnagnina Bus Station5:45 PMBrnoHotel Grand0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 5:25:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 12/25/2025 5:45:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 24h 20m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Rome to Brno
What are the most popular stations in Rome and Brno?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Brno you will be arriving at Train station, Židenice or Hotel Grand, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brno from Rome? With 7 connections between 2 Bus, Flight and Carpool operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Brno, you can pay as low as $84 with a Bus from RegioJet.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Brno in just 10h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Brno are FlixBus, Ryanair and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Brno is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Moravany, and look at flights from Rome Ciampino Airport, and landing at Brno Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Brno?
The most popular companies between Rome and Brno, are FlixBus, Ryanair and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Ryanair, Skyscanner, LC Perú and 2 more.
All you need to know when you travel from Rome to Brno
Check all information on comfort and services on all modes of transports from Rome to Brno. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Brno
How can I reach Brno from Rome?
Every day, there are on average 7 connections between Bus, Flight and Carpool, with which you can get to Brno from Rome.
How far is Brno from Rome?
The distance between Rome and Brno is 541.7 miles.
What is the most ecofriendly mode of transport between Rome and Brno?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 148 kgs, and a flight 214 kgs.
What is the cheapest mode of transport from Rome to Brno?
You can get to Brno with just $84 by taking a Bus from RegioJet.
What is the fastest way to get from Rome to Brno?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brno in just 10h 50m with a Flight from Ryanair.
More routes to Rome and to Brno
Looking for more options? Here you can see the most popular routes to Rome and to Brno. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Foggia to Rome
- Genoa to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Brno
- Bratislava to Brno
- Břeclav to Brno
- Česká Třebová to Brno
- Dusseldorf to Brno
- Florence to Brno
- Györ to Brno
- Jihlava to Brno
- Katowice Airport to Brno
- Krakow to Brno
- Kysak to Brno
- Munich to Brno
- Olomouc to Brno
- Ostrava to Brno
- Pilsen to Brno
- Prague Airport to Brno
- Prague to Brno
- Split to Brno
- Uherský Brod to Brno
- Vienna Airport to Brno
- Vienna to Brno
- Zlín to Brno
- Zurich to Brno
- Zvolen to Brno

