What is the best way to travel from San Antonio, TX to Mesa, AZ?
Looking for a trip? Compare all the available Buses and Flights for the journey to Mesa, AZ from San Antonio, TX. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Mesa, AZ from San Antonio, TX?
You can get to Mesa, AZ with just $61 by taking a Flight from Frontier Airlines, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/6/2025 3:45:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 22h 35m
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Greyhound US31h 30m012:40 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 12:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/6/2025 7:10:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 31h 30m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/6/2025 9:05:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 27h 55m
Cheapest Buses Friday
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/7/2025 3:45:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 35m
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Greyhound US31h 30m012:40 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 12:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/7/2025 7:10:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 31h 30m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/7/2025 9:05:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 27h 55m
Cheapest Buses Saturday
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/9/2025 3:45:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 35m
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Greyhound US31h 30m012:40 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 12:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/9/2025 7:10:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 31h 30m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/9/2025 9:05:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 27h 55m
Cheapest Buses Monday
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/11/2025 3:45:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 22h 35m
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Greyhound US31h 35m012:35 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 12:35:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/11/2025 7:10:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 31h 35m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/11/2025 9:05:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 27h 55m
Cheapest Buses Wednesday
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Frontier Airlines18h 0m03:06 PMSan Antonio AirportSan Antonio Airport8:06 AMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 3:06:00 PM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 8:06:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 0m
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Frontier Airlines13h 10m07:56 PMSan Antonio AirportSan Antonio Airport8:06 AMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 7:56:00 PM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 8:06:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 13h 10m
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Spirit Airlines10h 11m05:40 AMSan Antonio AirportSan Antonio Airport2:51 PMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 5:40:00 AM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/11/2025 2:51:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 10h 11m
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Alaska Airlines19h 5m06:00 AMSan Antonio AirportSan Antonio Airport12:05 AMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 6:00:00 AM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 12:05:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 19h 5m
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Alaska Airlines18h 28m06:55 PMSan Antonio AirportSan Antonio Airport12:23 PMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 6:55:00 PM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 12:23:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 18h 28m
Cheapest Flights Thursday
What are the fastest trips from San Antonio, TX to Mesa, AZ?
You can get to Mesa, AZ from San Antonio, TX in just 10h 11m with a Flight from Spirit Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/6/2025 3:45:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 22h 35m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/6/2025 9:05:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 27h 55m
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Greyhound US31h 30m012:40 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 12:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/6/2025 7:10:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 31h 30m
Fastest Buses Friday
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/7/2025 3:45:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 35m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/7/2025 9:05:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 27h 55m
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Greyhound US31h 30m012:40 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 12:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/7/2025 7:10:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 31h 30m
Fastest Buses Saturday
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/9/2025 3:45:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 35m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/9/2025 9:05:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 27h 55m
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Greyhound US31h 30m012:40 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 12:40:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/9/2025 7:10:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 31h 30m
Fastest Buses Monday
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Greyhound US22h 35m06:10 AMSan Antonio, TXBus Station3:45 AMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 6:10:00 AM to Greyhound, Mesa, AZ (USA) arriving at 12/11/2025 3:45:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 22h 35m
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FlixBus27h 55m06:10 PMSan Antonio, TXBus Station9:05 PMMesa, AZGreyhound0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 6:10:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/11/2025 9:05:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 27h 55m
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Greyhound US31h 35m012:35 PMSan Antonio, TXBus Station7:10 PMMesa, AZGreyhound0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 12:35:00 PM to Greyhound, Mesa, AZ (USA) arriving at 12/11/2025 7:10:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 31h 35m
Fastest Buses Wednesday
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Spirit Airlines10h 11m05:40 AMSan Antonio AirportSan Antonio Airport2:51 PMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 5:40:00 AM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/11/2025 2:51:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 10h 11m
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Frontier Airlines13h 10m07:56 PMSan Antonio AirportSan Antonio Airport8:06 AMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 7:56:00 PM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 8:06:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 13h 10m
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Frontier Airlines18h 0m03:06 PMSan Antonio AirportSan Antonio Airport8:06 AMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 3:06:00 PM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 8:06:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 0m
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Alaska Airlines18h 28m06:55 PMSan Antonio AirportSan Antonio Airport12:23 PMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 6:55:00 PM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 12:23:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 18h 28m
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Alaska Airlines19h 5m06:00 AMSan Antonio AirportSan Antonio Airport12:05 AMPhoenix Sky Harbor AirportPhoenix Sky Harbor Airport0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 12/11/2025 6:00:00 AM to Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) arriving at 12/12/2025 12:05:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 19h 5m
Fastest Flights Thursday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to Mesa, AZ
What are the most popular stations in San Antonio, TX and Mesa, AZ?
In San Antonio, TX, you will usually depart from Tornado Bus Company, Bus Station or W. Southcross & Buffalo Bus Stop, while in Mesa, AZ you will be arriving at Greyhound or Fry’s Fuel Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Mesa, AZ from San Antonio, TX? With 3 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and Mesa, AZ, you can pay as low as $61 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Spirit Airlines: you will get to Mesa, AZ in just 10h 11m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and Mesa, AZ are Greyhound US, FlixBus and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and Mesa, AZ is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Tempe, AZ, and look at flights from San Antonio Airport, and landing at Phoenix Sky Harbor Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to Mesa, AZ?
The most popular companies between San Antonio, TX and Mesa, AZ, are Greyhound US, FlixBus and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Frontier Airlines, Alaska Airlines and Spirit Airlines
All you need to know when you travel from San Antonio, TX to Mesa, AZ
Check all information on comfort and services on all modes of transports from San Antonio, TX to Mesa, AZ. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to Mesa, AZ
How can I reach Mesa, AZ from San Antonio, TX?
Every day, there are on average 3 connections between Bus and Flight, with which you can get to Mesa, AZ from San Antonio, TX.
How far is Mesa, AZ from San Antonio, TX?
The distance between San Antonio, TX and Mesa, AZ is 833.1 miles.
What is the most ecofriendly mode of transport between San Antonio, TX and Mesa, AZ?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 36 kgs of CO2, a train 47 kgs, a car 228 kgs, and a flight 330 kgs.
What is the cheapest mode of transport from San Antonio, TX to Mesa, AZ?
You can get to Mesa, AZ with just $61 by taking a Flight from Frontier Airlines.
What is the fastest way to get from San Antonio, TX to Mesa, AZ?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Mesa, AZ in just 10h 11m with a Flight from Spirit Airlines.
More routes to San Antonio, TX and to Mesa, AZ
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to Mesa, AZ. Simply click on a connection, and you’ll find all the details about the route!
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