What is the best way to travel from Siena to Lecce?
Looking for a trip? Compare all the available Trains and Buses for the journey to Lecce from Siena. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Lecce from Siena?
You can get to Lecce with just $23 by taking a Bus from Itabus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLecceCentral Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 4/28/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/28/2026 9:00:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 35m
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Itabus11h 35m09:25 AMSienaCentral Bus Station9:00 PMLecceCentral Bus Station0BasicA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 4/28/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/28/2026 9:00:00 PM. 50 Basic ticket for $27 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLeccePiazza Carmelo Bene Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 4/28/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/29/2026 9:00:00 AM. 50 Basic ticket for $48 per person are available. Travel duration is 12h 30m
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MarinoBus11h 35m011:05 AMSienaCentral Bus Station10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 4/28/2026 11:05:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/28/2026 10:40:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 11h 35m
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FlixBus14h 20m010:45 AMSienaTrain Station1:05 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 4/28/2026 10:45:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/29/2026 1:05:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 20m
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Trenitalia13h 31m09:18 AMSienaTrain Station10:49 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 9:18:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 10:49:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 13h 31m
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Trenitalia13h 59m06:36 AMSienaTrain Station8:35 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 6:36:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 8:35:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 13h 59m
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Trenitalia13h 12m08:18 PMSienaTrain Station9:30 AMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 8:18:00 PM to Central Station, Lecce (Italy) arriving at 4/29/2026 9:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 12m
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Trenitalia12h 54m06:25 AMSienaTrain Station7:19 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 6:25:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 7:19:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 54m
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Trenitalia11h 47m08:48 AMSienaTrain Station8:35 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 8:48:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 8:35:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 11h 47m
Cheapest Buses Tuesday
Cheapest Trains Tuesday
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Itabus11h 35m09:25 AMSienaCentral Bus Station9:00 PMLecceCentral Bus Station0BasicA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 4/29/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/29/2026 9:00:00 PM. 50 Basic ticket for $43 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaCentral Bus Station9:00 AMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 4/29/2026 8:30:00 PM to Central Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 AM. 50 Basic ticket for $52 per person are available. Travel duration is 12h 30m
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 4/29/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/29/2026 9:00:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 35m
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MarinoBus11h 35m011:05 AMSienaCentral Bus Station10:40 PMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 4/29/2026 11:05:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/29/2026 10:40:00 PM. 50 Basic ticket for $61 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaPiazza Antonio Gramsci9:00 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 4/29/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 30m
Cheapest Buses Wednesday
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLecceCentral Bus Station0EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 4/30/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 35m
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 4/30/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 4/30/2026 8:30:00 PM to Central Bus Station, Lecce (Italy) arriving at 5/1/2026 9:00:00 AM. 50 Basic ticket for $57 per person are available. Travel duration is 12h 30m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLeccePiazza Carmelo Bene Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 4/30/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 9:00:00 AM. 50 Basic ticket for $61 per person are available. Travel duration is 12h 30m
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FlixBus12h 25m012:40 PMSienaTrain Station1:05 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 4/30/2026 12:40:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 1:05:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 25m
Cheapest Buses Thursday
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FlixBus16h 5m06:40 PMSienaTrain Station10:45 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/1/2026 6:40:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 10:45:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 16h 5m
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FlixBus12h 20m06:25 PMSienaTrain Station6:45 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/1/2026 6:25:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 6:45:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 12h 20m
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/1/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 9:00:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaPiazza Antonio Gramsci9:00 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/1/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 9:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 30m
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MarinoBus11h 35m011:05 AMSienaPiazza Antonio Gramsci10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/1/2026 11:05:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 10:40:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 11h 35m
Cheapest Buses Friday
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FlixBus13h 55m08:45 AMSienaTrain Station10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/2/2026 8:45:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 10:40:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 55m
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FlixBus15h 54m02:51 PMSienaBus Stop6:45 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 5/2/2026 2:51:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 6:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 15h 54m
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/2/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 9:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaPiazza Antonio Gramsci9:00 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/2/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 9:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 30m
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MarinoBus11h 35m011:05 AMSienaPiazza Antonio Gramsci10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/2/2026 11:05:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 10:40:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 11h 35m
Cheapest Buses Saturday
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FlixBus16h 5m010:25 PMSienaTrain Station2:30 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/3/2026 10:25:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 2:30:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 16h 5m
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FlixBus12h 25m012:40 PMSienaTrain Station1:05 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/3/2026 12:40:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 1:05:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 12h 25m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLeccePiazza Carmelo Bene Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 5/3/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 9:00:00 AM. 50 Basic ticket for $58 per person are available. Travel duration is 12h 30m
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLeccePiazza Carmelo Bene Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 5/3/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 9:00:00 PM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 11h 35m
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/3/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 9:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 35m
Cheapest Buses Sunday
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FlixBus16h 5m010:25 PMSienaTrain Station2:30 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/4/2026 10:25:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/5/2026 2:30:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 16h 5m
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FlixBus15h 40m07:00 AMSienaTrain Station10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/4/2026 7:00:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 10:40:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 15h 40m
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLecceCentral Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 5/4/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 5/4/2026 9:00:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 11h 35m
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Itabus13h 50m05:15 AMSienaTrain Station7:05 PMLecceCentral Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 5/4/2026 5:15:00 AM to Central Bus Station, Lecce (Italy) arriving at 5/4/2026 7:05:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 13h 50m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 5/4/2026 8:30:00 PM to Central Bus Station, Lecce (Italy) arriving at 5/5/2026 9:00:00 AM. 50 Basic ticket for $48 per person are available. Travel duration is 12h 30m
Cheapest Buses Monday
What are the fastest trips from Siena to Lecce?
You can get to Lecce from Siena in just 11h 35m with a Bus from Itabus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLecceCentral Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 4/28/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/28/2026 9:00:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 35m
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Itabus11h 35m09:25 AMSienaCentral Bus Station9:00 PMLecceCentral Bus Station0BasicA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 4/28/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/28/2026 9:00:00 PM. 50 Basic ticket for $27 per person are available. Travel duration is 11h 35m
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MarinoBus11h 35m011:05 AMSienaCentral Bus Station10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 4/28/2026 11:05:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/28/2026 10:40:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLeccePiazza Carmelo Bene Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 4/28/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/29/2026 9:00:00 AM. 50 Basic ticket for $48 per person are available. Travel duration is 12h 30m
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FlixBus14h 20m010:45 AMSienaTrain Station1:05 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 4/28/2026 10:45:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/29/2026 1:05:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 20m
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Trenitalia11h 47m08:48 AMSienaTrain Station8:35 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 8:48:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 8:35:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 11h 47m
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Trenitalia12h 54m06:25 AMSienaTrain Station7:19 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 6:25:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 7:19:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 54m
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Trenitalia13h 12m08:18 PMSienaTrain Station9:30 AMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 8:18:00 PM to Central Station, Lecce (Italy) arriving at 4/29/2026 9:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 12m
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Trenitalia13h 31m09:18 AMSienaTrain Station10:49 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 9:18:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 10:49:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 13h 31m
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Trenitalia13h 59m06:36 AMSienaTrain Station8:35 PMLecceCentral Station0EconomyA Train from Trenitalia goes from Train Station, Siena (Italy) at 4/28/2026 6:36:00 AM to Central Station, Lecce (Italy) arriving at 4/28/2026 8:35:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 13h 59m
Fastest Buses Tuesday
Fastest Trains Tuesday
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Itabus11h 35m09:25 AMSienaCentral Bus Station9:00 PMLecceCentral Bus Station0BasicA Bus from Itabus goes from Central Bus Station, Siena (Italy) at 4/29/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/29/2026 9:00:00 PM. 50 Basic ticket for $43 per person are available. Travel duration is 11h 35m
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 4/29/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/29/2026 9:00:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 35m
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MarinoBus11h 35m011:05 AMSienaCentral Bus Station10:40 PMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 4/29/2026 11:05:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/29/2026 10:40:00 PM. 50 Basic ticket for $61 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaCentral Bus Station9:00 AMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Central Bus Station, Siena (Italy) at 4/29/2026 8:30:00 PM to Central Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 AM. 50 Basic ticket for $52 per person are available. Travel duration is 12h 30m
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MarinoBus12h 30m08:30 PMSienaPiazza Antonio Gramsci9:00 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 4/29/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 30m
Fastest Buses Wednesday
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLecceCentral Bus Station0EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 4/30/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 35m
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 4/30/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 4/30/2026 9:00:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 35m
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FlixBus12h 25m012:40 PMSienaTrain Station1:05 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 4/30/2026 12:40:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 1:05:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 25m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 4/30/2026 8:30:00 PM to Central Bus Station, Lecce (Italy) arriving at 5/1/2026 9:00:00 AM. 50 Basic ticket for $57 per person are available. Travel duration is 12h 30m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLeccePiazza Carmelo Bene Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 4/30/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 9:00:00 AM. 50 Basic ticket for $61 per person are available. Travel duration is 12h 30m
Fastest Buses Thursday
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/1/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 9:00:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 11h 35m
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MarinoBus11h 35m011:05 AMSienaPiazza Antonio Gramsci10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/1/2026 11:05:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/1/2026 10:40:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 11h 35m
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FlixBus12h 20m06:25 PMSienaTrain Station6:45 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/1/2026 6:25:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 6:45:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 12h 20m
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MarinoBus12h 30m08:30 PMSienaPiazza Antonio Gramsci9:00 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/1/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 9:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 30m
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FlixBus16h 5m06:40 PMSienaTrain Station10:45 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/1/2026 6:40:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 10:45:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 16h 5m
Fastest Buses Friday
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/2/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 9:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 11h 35m
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MarinoBus11h 35m011:05 AMSienaPiazza Antonio Gramsci10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/2/2026 11:05:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 10:40:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaPiazza Antonio Gramsci9:00 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from MarinoBus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/2/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 9:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 30m
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FlixBus13h 55m08:45 AMSienaTrain Station10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/2/2026 8:45:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/2/2026 10:40:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 13h 55m
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FlixBus15h 54m02:51 PMSienaBus Stop6:45 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Bus Stop, Siena (Italy) at 5/2/2026 2:51:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 6:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 15h 54m
Fastest Buses Saturday
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLeccePiazza Carmelo Bene Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 5/3/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 9:00:00 PM. 50 Premium Economy ticket for $60 per person are available. Travel duration is 11h 35m
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Itabus11h 35m09:25 AMSienaPiazza Antonio Gramsci9:00 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 5/3/2026 9:25:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/3/2026 9:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 11h 35m
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FlixBus12h 25m012:40 PMSienaTrain Station1:05 AMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/3/2026 12:40:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 1:05:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 12h 25m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLeccePiazza Carmelo Bene Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 5/3/2026 8:30:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 9:00:00 AM. 50 Basic ticket for $58 per person are available. Travel duration is 12h 30m
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FlixBus16h 5m010:25 PMSienaTrain Station2:30 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/3/2026 10:25:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 2:30:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 16h 5m
Fastest Buses Sunday
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Itabus11h 35m09:25 AMSienaTrain Station9:00 PMLecceCentral Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 5/4/2026 9:25:00 AM to Central Bus Station, Lecce (Italy) arriving at 5/4/2026 9:00:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 11h 35m
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MarinoBus12h 30m08:30 PMSienaTrain Station9:00 AMLecceCentral Bus Station0BasicA Bus from MarinoBus goes from Train Station, Siena (Italy) at 5/4/2026 8:30:00 PM to Central Bus Station, Lecce (Italy) arriving at 5/5/2026 9:00:00 AM. 50 Basic ticket for $48 per person are available. Travel duration is 12h 30m
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Itabus13h 50m05:15 AMSienaTrain Station7:05 PMLecceCentral Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 5/4/2026 5:15:00 AM to Central Bus Station, Lecce (Italy) arriving at 5/4/2026 7:05:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 13h 50m
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FlixBus15h 40m07:00 AMSienaTrain Station10:40 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/4/2026 7:00:00 AM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/4/2026 10:40:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 15h 40m
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FlixBus16h 5m010:25 PMSienaTrain Station2:30 PMLeccePiazza Carmelo Bene Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 5/4/2026 10:25:00 PM to Piazza Carmelo Bene Bus Station, Lecce (Italy) arriving at 5/5/2026 2:30:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 16h 5m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Siena to Lecce
What are the most popular stations in Siena and Lecce?
In Siena, you will usually depart from Bus Stop, Train Station or Central Bus Station, while in Lecce you will be arriving at Piazza Carmelo Bene Bus Station, Central Bus Station or Central Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lecce from Siena? With 5 connections between 4 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Siena and Lecce, you can pay as low as $23 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Itabus: you will get to Lecce in just 11h 35m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Siena and Lecce are MarinoBus, Itabus and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Siena and Lecce is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Castagno or to Merine, and look at flights from , and landing at Brindisi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Siena to Lecce?
The most popular companies between Siena and Lecce, are MarinoBus, Itabus and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: MarinoBus, Itabus and FlixBus
Train companies: Trenitalia
All you need to know when you travel from Siena to Lecce
Check all information on comfort and services on all modes of transports from Siena to Lecce. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Siena to Lecce
How can I reach Lecce from Siena?
Every day, there are on average 5 connections between Train and Bus, with which you can get to Lecce from Siena.
How far is Lecce from Siena?
The distance between Siena and Lecce is 407.6 miles.
What is the most ecofriendly mode of transport between Siena and Lecce?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 18 kgs of CO2, a train 23 kgs, a car 112 kgs, and a flight 161 kgs.
What is the cheapest mode of transport from Siena to Lecce?
You can get to Lecce with just $23 by taking a Bus from Itabus.
What is the fastest way to get from Siena to Lecce?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lecce in just 11h 35m with a Bus from Itabus.
More routes to Siena and to Lecce
Looking for more options? Here you can see the most popular routes to Siena and to Lecce. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Siena
- Assisi to Siena
- Avellino to Siena
- Bari to Siena
- Bologna to Siena
- Caserta to Siena
- Cassino to Siena
- Cosenza to Siena
- Florence to Siena
- Frosinone to Siena
- Grosseto to Siena
- Lucca to Siena
- Milan to Siena
- Naples to Siena
- Perugia to Siena
- Pescara to Siena
- Pisa to Siena
- Prato to Siena
- Rome to Siena
- Salerno to Siena
- Sicignano degli Alburni to Siena
- Taranto to Siena
- Turin to Siena
- Trips to Lecce
- Bari Airport to Lecce
- Bologna to Lecce
- Brindisi Airport to Lecce
- Catania to Lecce
- Cosenza to Lecce
- Fasano to Lecce
- Foggia to Lecce
- Galatone to Lecce
- Gallipoli to Lecce
- Milan to Lecce
- Naples to Lecce
- Nardò to Lecce
- Orvieto to Lecce
- Otranto to Lecce
- Palermo to Lecce
- Pescara to Lecce
- Potenza to Lecce
- Rimini to Lecce
- Salerno to Lecce
- Taranto to Lecce
- Turin to Lecce
- Ugento to Lecce
