What is the best way to travel from Southampton to Middlesbrough?
Looking for a trip? Compare all the available Flights, Trains and Buses for the journey to Middlesbrough from Southampton. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Middlesbrough from Southampton?
You can get to Middlesbrough with just $26 by taking a Bus from National Express, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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National Express10h 5m05:50 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/17/2026 5:50:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/18/2026 3:55:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 5m
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National Express10h 55m012:45 PMSouthamptonBus Station11:40 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/17/2026 12:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/17/2026 11:40:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 55m
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National Express10h 40m010:05 AMSouthamptonBus Station8:45 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/17/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/17/2026 8:45:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 10h 40m
Cheapest Buses Saturday
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/18/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/18/2026 12:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 35m
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National Express10h 55m012:45 PMSouthamptonBus Station11:40 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/18/2026 12:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/18/2026 11:40:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 55m
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National Express10h 5m05:50 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/18/2026 5:50:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 3:55:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 10h 5m
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FlixBus9h 40m04:45 PMSouthamptonBus Station2:25 AMMiddlesbroughBus Station0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/18/2026 4:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 2:25:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 9h 40m
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KLM Cityhopper7h 55m09:15 AMSouthampton AirportSouthampton Airport5:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/18/2026 9:15:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/18/2026 5:10:00 PM. 50 Economy ticket for $393 per person are available. Travel duration is 7h 55m
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KLM Cityhopper4h 10m05:20 PMSouthampton AirportSouthampton Airport9:30 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/18/2026 5:20:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/18/2026 9:30:00 PM. 50 Economy ticket for $393 per person are available. Travel duration is 4h 10m
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EasyJet Airline9h 45m08:25 AMSouthampton AirportSouthampton Airport6:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/18/2026 8:25:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/18/2026 6:10:00 PM. 50 Economy ticket for $503 per person are available. Travel duration is 9h 45m
Cheapest Buses Sunday
Cheapest Flights Sunday
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National Express9h 20m06:35 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 6:35:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 3:55:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 20m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 12:55:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 35m
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National Express11h 10m012:15 PMSouthamptonBus Station11:25 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 12:15:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 11:25:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 11h 10m
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National Express10h 0m010:05 AMSouthamptonBus Station8:05 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 8:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 0m
Cheapest Buses Monday
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National Express9h 20m06:35 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 6:35:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 3:55:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 9h 20m
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National Express11h 10m012:15 PMSouthamptonBus Station11:25 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 12:15:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 11:25:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 11h 10m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 12:55:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 10h 35m
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National Express10h 0m010:05 AMSouthamptonBus Station8:05 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 8:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 0m
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Ryanair20h 25m011:25 AMBournemouth AirportBournemouth Airport7:50 AMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from Ryanair goes from Bournemouth Airport, Bournemouth Airport (United Kingdom) at 10/20/2026 11:25:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/21/2026 7:50:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 20h 25m
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Ryanair11h 10m08:40 PMBournemouth AirportBournemouth Airport7:50 AMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from Ryanair goes from Bournemouth Airport, Bournemouth Airport (United Kingdom) at 10/20/2026 8:40:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/21/2026 7:50:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 11h 10m
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KLM Cityhopper8h 5m09:05 AMSouthampton AirportSouthampton Airport5:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/20/2026 9:05:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/20/2026 5:10:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 8h 5m
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KLM Cityhopper4h 10m05:20 PMSouthampton AirportSouthampton Airport9:30 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/20/2026 5:20:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/20/2026 9:30:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 4h 10m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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National Express11h 10m012:15 PMSouthamptonBus Station11:25 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 12:15:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 11:25:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 11h 10m
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National Express9h 20m06:35 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 6:35:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/22/2026 3:55:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 9h 20m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 12:55:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 10h 35m
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National Express10h 0m010:05 AMSouthamptonBus Station8:05 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 8:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 0m
Cheapest Buses Wednesday
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Ryanair9h 45m08:40 AMBournemouth AirportBournemouth Airport6:25 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from Ryanair goes from Bournemouth Airport, Bournemouth Airport (United Kingdom) at 10/22/2026 8:40:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/22/2026 6:25:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 9h 45m
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KLM Cityhopper4h 10m05:20 PMSouthampton AirportSouthampton Airport9:30 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/22/2026 5:20:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/22/2026 9:30:00 PM. 50 Economy ticket for $323 per person are available. Travel duration is 4h 10m
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KLM Cityhopper8h 5m09:05 AMSouthampton AirportSouthampton Airport5:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/22/2026 9:05:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/22/2026 5:10:00 PM. 50 Economy ticket for $496 per person are available. Travel duration is 8h 5m
Cheapest Flights Thursday
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National Express11h 10m012:45 PMSouthamptonBus Station11:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/23/2026 12:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 11:55:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 11h 10m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/23/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 12:55:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 35m
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National Express10h 5m05:50 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/23/2026 5:50:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/24/2026 3:55:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 5m
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FlixBus9h 40m04:45 PMSouthamptonBus Station2:25 AMMiddlesbroughBus Station0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/23/2026 4:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/24/2026 2:25:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 9h 40m
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South Western Railway6h 0m04:49 AMSouthamptonCentral Station10:49 AMMiddlesbroughCentral Station0EconomyA Train from South Western Railway goes from Central Station, Southampton (United Kingdom) at 10/23/2026 4:49:00 AM to Central Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 10:49:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 6h 0m
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CrossCountry6h 21m05:15 AMSouthamptonCentral Station11:36 AMMiddlesbroughCentral Station0EconomyA Train from CrossCountry goes from Central Station, Southampton (United Kingdom) at 10/23/2026 5:15:00 AM to Central Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 11:36:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 6h 21m
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South Western Railway6h 26m04:49 AMSouthamptonCentral Station11:15 AMMiddlesbroughNunthorpe Train Station0EconomyA Train from South Western Railway goes from Central Station, Southampton (United Kingdom) at 10/23/2026 4:49:00 AM to Nunthorpe Train Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 11:15:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 6h 26m
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South Western Railway6h 22m05:52 AMSouthamptonCentral Station12:14 PMMiddlesbroughNunthorpe Train Station0EconomyA Train from South Western Railway goes from Central Station, Southampton (United Kingdom) at 10/23/2026 5:52:00 AM to Nunthorpe Train Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 12:14:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 6h 22m
Cheapest Buses Friday
Cheapest Trains Friday
What are the fastest trips from Southampton to Middlesbrough?
You can get to Middlesbrough from Southampton in just 4h 10m with a Flight from KLM Cityhopper. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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National Express10h 5m05:50 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/17/2026 5:50:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/18/2026 3:55:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 5m
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National Express10h 40m010:05 AMSouthamptonBus Station8:45 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/17/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/17/2026 8:45:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 10h 40m
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National Express10h 55m012:45 PMSouthamptonBus Station11:40 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/17/2026 12:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/17/2026 11:40:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 55m
Fastest Buses Saturday
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KLM Cityhopper4h 10m05:20 PMSouthampton AirportSouthampton Airport9:30 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/18/2026 5:20:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/18/2026 9:30:00 PM. 50 Economy ticket for $393 per person are available. Travel duration is 4h 10m
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KLM Cityhopper7h 55m09:15 AMSouthampton AirportSouthampton Airport5:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/18/2026 9:15:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/18/2026 5:10:00 PM. 50 Economy ticket for $393 per person are available. Travel duration is 7h 55m
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EasyJet Airline9h 45m08:25 AMSouthampton AirportSouthampton Airport6:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from EasyJet Airline goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/18/2026 8:25:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/18/2026 6:10:00 PM. 50 Economy ticket for $503 per person are available. Travel duration is 9h 45m
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FlixBus9h 20m05:05 PMSouthamptonUniversity2:25 AMMiddlesbroughBus Station0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/18/2026 5:05:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 2:25:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 9h 20m
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FlixBus9h 40m04:45 PMSouthamptonBus Station2:25 AMMiddlesbroughBus Station0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/18/2026 4:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 2:25:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 9h 40m
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National Express10h 5m05:50 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/18/2026 5:50:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 3:55:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 10h 5m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/18/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/18/2026 12:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 35m
Fastest Flights Sunday
Fastest Buses Sunday
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National Express9h 20m06:35 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 6:35:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 3:55:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 20m
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National Express10h 0m010:05 AMSouthamptonBus Station8:05 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 8:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 0m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 12:55:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 10h 35m
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National Express11h 10m012:15 PMSouthamptonBus Station11:25 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/19/2026 12:15:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/19/2026 11:25:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 11h 10m
Fastest Buses Monday
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KLM Cityhopper4h 10m05:20 PMSouthampton AirportSouthampton Airport9:30 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/20/2026 5:20:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/20/2026 9:30:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 4h 10m
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KLM Cityhopper8h 5m09:05 AMSouthampton AirportSouthampton Airport5:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/20/2026 9:05:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/20/2026 5:10:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 8h 5m
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Ryanair11h 10m08:40 PMBournemouth AirportBournemouth Airport7:50 AMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from Ryanair goes from Bournemouth Airport, Bournemouth Airport (United Kingdom) at 10/20/2026 8:40:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/21/2026 7:50:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 11h 10m
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Ryanair20h 25m011:25 AMBournemouth AirportBournemouth Airport7:50 AMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from Ryanair goes from Bournemouth Airport, Bournemouth Airport (United Kingdom) at 10/20/2026 11:25:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/21/2026 7:50:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 20h 25m
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National Express9h 20m06:35 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 6:35:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 3:55:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 9h 20m
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National Express10h 0m010:05 AMSouthamptonBus Station8:05 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 8:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 0m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 12:55:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 10h 35m
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National Express11h 10m012:15 PMSouthamptonBus Station11:25 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/20/2026 12:15:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/20/2026 11:25:00 PM. 50 Economy ticket for $29 per person are available. Travel duration is 11h 10m
Fastest Flights Tuesday
Fastest Buses Tuesday
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National Express9h 20m06:35 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 6:35:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/22/2026 3:55:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 9h 20m
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National Express10h 0m010:05 AMSouthamptonBus Station8:05 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 10:05:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 8:05:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 0m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 12:55:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 10h 35m
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National Express11h 10m012:15 PMSouthamptonBus Station11:25 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/21/2026 12:15:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/21/2026 11:25:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 11h 10m
Fastest Buses Wednesday
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KLM Cityhopper4h 10m05:20 PMSouthampton AirportSouthampton Airport9:30 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/22/2026 5:20:00 PM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/22/2026 9:30:00 PM. 50 Economy ticket for $323 per person are available. Travel duration is 4h 10m
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KLM Cityhopper8h 5m09:05 AMSouthampton AirportSouthampton Airport5:10 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from KLM Cityhopper goes from Southampton Airport, Southampton Airport (United Kingdom) at 10/22/2026 9:05:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/22/2026 5:10:00 PM. 50 Economy ticket for $496 per person are available. Travel duration is 8h 5m
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Ryanair9h 45m08:40 AMBournemouth AirportBournemouth Airport6:25 PMDurham Tees Valley AirportDurham Tees Valley Airport0EconomyA Flight from Ryanair goes from Bournemouth Airport, Bournemouth Airport (United Kingdom) at 10/22/2026 8:40:00 AM to Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) arriving at 10/22/2026 6:25:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 9h 45m
Fastest Flights Thursday
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South Western Railway6h 0m04:49 AMSouthamptonCentral Station10:49 AMMiddlesbroughCentral Station0EconomyA Train from South Western Railway goes from Central Station, Southampton (United Kingdom) at 10/23/2026 4:49:00 AM to Central Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 10:49:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 6h 0m
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CrossCountry6h 21m05:15 AMSouthamptonCentral Station11:36 AMMiddlesbroughCentral Station0EconomyA Train from CrossCountry goes from Central Station, Southampton (United Kingdom) at 10/23/2026 5:15:00 AM to Central Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 11:36:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 6h 21m
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South Western Railway6h 22m05:52 AMSouthamptonCentral Station12:14 PMMiddlesbroughNunthorpe Train Station0EconomyA Train from South Western Railway goes from Central Station, Southampton (United Kingdom) at 10/23/2026 5:52:00 AM to Nunthorpe Train Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 12:14:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 6h 22m
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South Western Railway6h 26m04:49 AMSouthamptonCentral Station11:15 AMMiddlesbroughNunthorpe Train Station0EconomyA Train from South Western Railway goes from Central Station, Southampton (United Kingdom) at 10/23/2026 4:49:00 AM to Nunthorpe Train Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 11:15:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 6h 26m
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FlixBus9h 20m05:05 PMSouthamptonUniversity2:25 AMMiddlesbroughBus Station0EconomyA Bus from FlixBus goes from University, Southampton (United Kingdom) at 10/23/2026 5:05:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/24/2026 2:25:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 9h 20m
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FlixBus9h 40m04:45 PMSouthamptonBus Station2:25 AMMiddlesbroughBus Station0EconomyA Bus from FlixBus goes from Bus Station, Southampton (United Kingdom) at 10/23/2026 4:45:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/24/2026 2:25:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 9h 40m
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National Express10h 5m05:50 PMSouthamptonBus Station3:55 AMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/23/2026 5:50:00 PM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/24/2026 3:55:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 5m
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National Express10h 35m02:20 AMSouthamptonBus Station12:55 PMMiddlesbroughBus Station0EconomyA Bus from National Express goes from Bus Station, Southampton (United Kingdom) at 10/23/2026 2:20:00 AM to Bus Station, Middlesbrough (United Kingdom) arriving at 10/23/2026 12:55:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 35m
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Here you will find all operators and timetables for a
Bus from Southampton to Middlesbrough
What are the most popular stations in Southampton and Middlesbrough?
In Southampton, you will usually depart from Bus Station, Central Station or SeaCity Museum, while in Middlesbrough you will be arriving at Bus Station, Central Station or South Bank Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Middlesbrough from Southampton? With 5 connections between 4 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Southampton and Middlesbrough, you can pay as low as $26 with a Bus from National Express.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from KLM Cityhopper: you will get to Middlesbrough in just 4h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Southampton and Middlesbrough are National Express, KLM Cityhopper and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Southampton and Middlesbrough is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Netley or to Thornaby, and look at flights from Bournemouth Airport, and landing at Durham Tees Valley Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Southampton to Middlesbrough?
The most popular companies between Southampton and Middlesbrough, are National Express, KLM Cityhopper and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: National Express and FlixBus
Train companies: South Western Railway and CrossCountry
Airlines: KLM Cityhopper, Ryanair and EasyJet Airline
All you need to know when you travel from Southampton to Middlesbrough
Check all information on comfort and services on all modes of transports from Southampton to Middlesbrough. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Southampton to Middlesbrough
How can I reach Middlesbrough from Southampton?
Every day, there are on average 5 connections between Flight, Train and Bus, with which you can get to Middlesbrough from Southampton.
How far is Middlesbrough from Southampton?
The distance between Southampton and Middlesbrough is 253.4 miles.
What is the most ecofriendly mode of transport between Southampton and Middlesbrough?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 69 kgs, and a flight 100 kgs.
What is the cheapest mode of transport from Southampton to Middlesbrough?
You can get to Middlesbrough with just $26 by taking a Bus from National Express.
What is the fastest way to get from Southampton to Middlesbrough?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Middlesbrough in just 4h 10m with a Flight from KLM Cityhopper.
More routes to Southampton and to Middlesbrough
Looking for more options? Here you can see the most popular routes to Southampton and to Middlesbrough. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Southampton
- Aberdeen to Southampton
- Birmingham to Southampton
- Blackpool to Southampton
- Bournemouth to Southampton
- Brighton to Southampton
- Bristol to Southampton
- Edinburgh to Southampton
- Exeter to Southampton
- Glasgow to Southampton
- Leeds to Southampton
- London Gatwick Airport to Southampton
- London to Southampton
- Middlesbrough to Southampton
- Newcastle upon Tyne to Southampton
- Oxford to Southampton
- Poole to Southampton
- Portsmouth to Southampton
- Ringwood to Southampton
- Sheffield to Southampton
- Trips to Middlesbrough
- Birmingham to Middlesbrough
- Bournemouth to Middlesbrough
- Bristol to Middlesbrough
- Glasgow to Middlesbrough
- Leicester to Middlesbrough
- Liverpool to Middlesbrough
- London to Middlesbrough
- Manchester to Middlesbrough
- Newcastle upon Tyne to Middlesbrough
- Nottingham to Middlesbrough
- York to Middlesbrough
