Bus Buffalo, NY to Chicago - Compare all Companies

Compare all timetables for the bus from Buffalo, NY to Chicago

Here is a selection of the cheapest bus trips from the schedule from Buffalo, NY to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today

$67

tomorrow

$78

Saturday

$77

Sunday

$64

Monday

$71

Tuesday

$67

Wednesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	11h 55m	11:05 PM	Buffalo, NY	Central Bus Station	10:00 AM	Chicago	Downtown Bus Station	Economy	$67	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/5/2026 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/6/2026 10:00:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 11h 55m
Greyhound US	15h 15m	11:05 PM	Buffalo, NY	Central Bus Station	1:20 PM	Chicago	95th Red Line Station	Economy	$69	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/5/2026 11:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 1:20:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 15h 15m
FlixBus	17h 45m	1:25 PM	Buffalo, NY	Central Bus Station	6:10 AM	Chicago	Downtown Bus Station	Economy	$70	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/5/2026 1:25:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/6/2026 6:10:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 45m
Greyhound US	13h 10m	7:55 AM	Buffalo, NY	Central Bus Station	8:05 PM	Chicago	Downtown Bus Station	Economy	$72	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/5/2026 7:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 11/5/2026 8:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 13h 10m
FlixBus	17h 15m	1:25 PM	Buffalo, NY	Central Bus Station	5:40 AM	Chicago	95th Red Line Station	Economy	$72	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/5/2026 1:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 5:40:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 17h 15m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	11h 55m	11:05 PM	Buffalo, NY	Central Bus Station	10:00 AM	Chicago	Downtown Bus Station	Economy	$78	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/6/2026 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/7/2026 10:00:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 11h 55m
Greyhound US	15h 15m	11:05 PM	Buffalo, NY	Central Bus Station	1:20 PM	Chicago	95th Red Line Station	Economy	$80	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/6/2026 11:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/7/2026 1:20:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 15h 15m
Greyhound US	13h 10m	7:55 AM	Buffalo, NY	Central Bus Station	8:05 PM	Chicago	Downtown Bus Station	Economy	$84	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/6/2026 7:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 11/6/2026 8:05:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 13h 10m
FlixBus	17h 45m	1:25 PM	Buffalo, NY	Central Bus Station	6:10 AM	Chicago	Downtown Bus Station	Economy	$84	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/6/2026 1:25:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/7/2026 6:10:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 17h 45m
FlixBus	17h 15m	1:25 PM	Buffalo, NY	Central Bus Station	5:40 AM	Chicago	95th Red Line Station	Economy	$86	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/6/2026 1:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/7/2026 5:40:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 15m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 10m	7:55 AM	Buffalo, NY	Central Bus Station	8:05 PM	Chicago	Downtown Bus Station	Economy	$77	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/7/2026 7:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 11/7/2026 8:05:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 13h 10m
Greyhound US	11h 55m	11:05 PM	Buffalo, NY	Central Bus Station	10:00 AM	Chicago	Downtown Bus Station	Economy	$77	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/7/2026 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/8/2026 10:00:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 11h 55m
FlixBus	17h 35m	1:05 PM	Buffalo, NY	Central Bus Station	5:40 AM	Chicago	95th Red Line Station	Economy	$77	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/7/2026 1:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/8/2026 5:40:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 35m
FlixBus	18h 5m	1:05 PM	Buffalo, NY	Central Bus Station	6:10 AM	Chicago	Downtown Bus Station	Economy	$77	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/7/2026 1:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/8/2026 6:10:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 18h 5m
Greyhound US	16h 35m	7:55 AM	Buffalo, NY	Central Bus Station	11:30 PM	Chicago	95th Red Line Station	Economy	$78	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/7/2026 7:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/7/2026 11:30:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 16h 35m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 10m	7:55 AM	Buffalo, NY	Central Bus Station	8:05 PM	Chicago	Downtown Bus Station	Economy	$64	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/8/2026 7:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 11/8/2026 8:05:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 13h 10m
Greyhound US	11h 55m	11:05 PM	Buffalo, NY	Central Bus Station	10:00 AM	Chicago	Downtown Bus Station	Economy	$64	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/8/2026 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/9/2026 10:00:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 11h 55m
FlixBus	18h 5m	1:05 PM	Buffalo, NY	Central Bus Station	6:10 AM	Chicago	Downtown Bus Station	Economy	$65	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/8/2026 1:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/9/2026 6:10:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 18h 5m
FlixBus	17h 35m	1:05 PM	Buffalo, NY	Central Bus Station	5:40 AM	Chicago	95th Red Line Station	Economy	$66	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/8/2026 1:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/9/2026 5:40:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 17h 35m
Greyhound US	16h 35m	7:55 AM	Buffalo, NY	Central Bus Station	11:30 PM	Chicago	95th Red Line Station	Economy	$67	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/8/2026 7:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/8/2026 11:30:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 16h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 10m	7:55 AM	Buffalo, NY	Central Bus Station	8:05 PM	Chicago	Downtown Bus Station	Economy	$71	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/9/2026 7:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 11/9/2026 8:05:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 13h 10m
Greyhound US	11h 55m	11:05 PM	Buffalo, NY	Central Bus Station	10:00 AM	Chicago	Downtown Bus Station	Economy	$71	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/9/2026 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/10/2026 10:00:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 11h 55m
FlixBus	17h 45m	1:25 PM	Buffalo, NY	Central Bus Station	6:10 AM	Chicago	Downtown Bus Station	Economy	$71	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/9/2026 1:25:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/10/2026 6:10:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 17h 45m
Greyhound US	16h 35m	7:55 AM	Buffalo, NY	Central Bus Station	11:30 PM	Chicago	95th Red Line Station	Economy	$73	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/9/2026 7:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/9/2026 11:30:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 35m
FlixBus	17h 15m	1:25 PM	Buffalo, NY	Central Bus Station	5:40 AM	Chicago	95th Red Line Station	Economy	$73	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 11/9/2026 1:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/10/2026 5:40:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 17h 15m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 10m	7:55 AM	Buffalo, NY	Central Bus Station	8:05 PM	Chicago	Downtown Bus Station	Economy	$67	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/10/2026 7:55:00 AM to Downtown Bus Station, Chicago (USA) arriving at 11/10/2026 8:05:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 13h 10m
Greyhound US	11h 55m	11:05 PM	Buffalo, NY	Central Bus Station	10:00 AM	Chicago	Downtown Bus Station	Economy	$67	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/10/2026 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/11/2026 10:00:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 11h 55m
Greyhound US	16h 35m	7:55 AM	Buffalo, NY	Central Bus Station	11:30 PM	Chicago	95th Red Line Station	Economy	$72	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/10/2026 7:55:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/10/2026 11:30:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 35m
Greyhound US	15h 20m	11:05 PM	Buffalo, NY	Central Bus Station	1:25 PM	Chicago	95th Red Line Station	Economy	$72	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 11/10/2026 11:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/11/2026 1:25:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 15h 20m

Best Price Offer: The price for the cheapest bus from Buffalo, NY to Chicago is $60 on 11/17/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Buffalo, NY and Chicago

See here how frequent the connections between Buffalo, NY and Chicago are, during different times and days of the week.

Sunday is the busiest day, with more than 12 daily buses from Buffalo, NY to Chicago. Tuesday has instead the fewest connections, with only 4 daily coaches between Buffalo, NY and Chicago.

The busiest time of the day is the Morning, with 22 buses from Buffalo, NY to Chicago, while Afternoon sees the fewest connections between Buffalo, NY and Chicago, with 20 offers.

Facts about the bus from Buffalo, NY to Chicago

Compare all providers like Greyhound US and FlixBus that travel 10 times every day by bus from Buffalo, NY to Chicago in one click! Book your bus ticket from Buffalo, NY to Chicago starting from $60!

Cheapest Bus	$60
Fastest Bus	10h 55m
Earliest Bus	7:55 AM
Latest Bus	11:05 PM
Daily Bus Routes	10 Ø
Distance	452.7 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Buffalo, NY to Chicago

Every day, 10 buses from 2 bus companies leave Buffalo, NY for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/05/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/01

Monday 11/02

Tuesday 11/03

Wednesday 11/04

Thursday 11/05

$67

Friday 11/06

$78

Saturday 11/07

$77

Sunday 11/08

$71

Monday 11/09

$71

Tuesday 11/10

$67

Wednesday 11/11

Thursday 11/12

$77

Friday 11/13

$73

Saturday 11/14

$70

Sunday 11/15

$72

Monday 11/16

$65

Tuesday 11/17

$60

Wednesday 11/18

Thursday 11/19

$88

Friday 11/20

$94

Saturday 11/21

$94

Sunday 11/22

Monday 11/23

$100

Tuesday 11/24

$106

Wednesday 11/25

$100

Thursday 11/26

$81

Friday 11/27

$89

Saturday 11/28

The cheapest time to travel from Buffalo, NY to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Buffalo, NY to Chicago, for the next 30 days.

With a price starting from $60, Tuesday is the cheapest day for a bus from Buffalo, NY to Chicago. Friday instead is the most expensive day with prices starting from $73.

Morning is the cheapest day time for bus tickets from Buffalo, NY to Chicago, with $64. Afternoon is the most expensive time of the day with prices starting from $65.

How to save money travelling from Buffalo, NY to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buffalo, NY to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buffalo, NY to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buffalo, NY to Chicago are also emptier.

Beloved bus companies from Buffalo, NY to Chicago

These are the most booked bus companies between Buffalo, NY to Chicago from our users.

Greyhound US from Buffalo, NY to Chicago

Here you will find the key facts about the Greyhound US bus route Buffalo, NY to Chicago:

Cheapest Price	$64
Fastest Bus	10h 55m
Earliest Bus	7:55 AM
Last Bus	11:05 PM
Daily Connections	7 Ø
Found on	11/4/2026

All bus stations and stops in Buffalo, NY and Chicago

In the map below, you can see where to find all bus stations in Buffalo, NY and Chicago.

Central Bus Station

Ellicott Street 181

MTC / Downtown Terminal

Ellicott Street 181

Maple Road Gulf

Maple Rd 4641

Cleveland Hall

Asia Food Market

Niagara Falls Blvd 2055

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Buffalo, NY to Chicago

Want to know which seat classes are available on the buses from Buffalo, NY to Chicago? Or which bus companies serve the route Buffalo, NY to Chicago? Below you will find answers to your questions.

FAQs about the Buffalo, NY to Chicago bus

How much does a Buffalo, NY Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $60 and takes 12h 10m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Buffalo, NY to Chicago?

This route is offered by 2 companies with a range of ticket prices between $60 and $113. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Buffalo, NY to Chicago each day?

Every day, the Buffalo, NY to Chicago bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buffalo, NY to Chicago take?

The fastest bus from Buffalo, NY to Chicago is offered by Greyhound US and takes 10h 55m. Bus tickets for this connection cost $67. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buffalo, NY to Chicago?

The earliest bus arriving in Chicago from Buffalo, NY starts at 7:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buffalo, NY to Chicago?

The latest bus trip departing from Buffalo, NY for Chicago starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buffalo, NY Chicago route?

When traveling by bus from Buffalo, NY to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buffalo, NY and Chicago?

You can check all the direct connections between Buffalo, NY and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Buffalo, NY to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buffalo, NY Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buffalo, NY Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buffalo, NY to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Buffalo, NY to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Buffalo, NY and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Buffalo, NY to Chicago?

Prices and availability for 10 trips between Buffalo, NY and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Buffalo, NY to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Buffalo, NY and to Chicago

Here’s an overview of the most popular bus routes to Buffalo, NY and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!