Bus Columbia, MO to Milwaukee - Compare all Companies

Compare all timetables for the bus from Columbia, MO to Milwaukee

Here is a selection of the cheapest bus trips from the schedule from Columbia, MO to Milwaukee from various bus operators like Greyhound US for the next days.

today

$77

tomorrow

$73

Saturday

$77

Sunday

$74

Monday

$78

Tuesday

$73

Wednesday

$76

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 25m	8:05 PM	Columbia, MO	Bus Stop	8:30 AM	Milwaukee	Central Bus Station	Economy	$77	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/4/2026 8:05:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/5/2026 8:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 25m
Greyhound US	11h 55m	8:35 PM	Columbia, MO	Red Thread	8:30 AM	Milwaukee	Central Bus Station	Economy	$77	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/4/2026 8:35:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/5/2026 8:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 11h 55m
Greyhound US	15h 30m	10:40 AM	Columbia, MO	Red Thread	2:10 AM	Milwaukee	Central Bus Station	Economy	$82	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/4/2026 10:40:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/5/2026 2:10:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 15h 30m
Greyhound US	17h 40m	8:30 AM	Columbia, MO	Bus Stop	2:10 AM	Milwaukee	Central Bus Station	Economy	$83	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/4/2026 8:30:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/5/2026 2:10:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 17h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 25m	8:05 PM	Columbia, MO	Bus Stop	8:30 AM	Milwaukee	Central Bus Station	Economy	$73	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/5/2026 8:05:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/6/2026 8:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 25m
Greyhound US	11h 55m	8:35 PM	Columbia, MO	Red Thread	8:30 AM	Milwaukee	Central Bus Station	Economy	$73	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/5/2026 8:35:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/6/2026 8:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 11h 55m
Greyhound US	17h 40m	8:30 AM	Columbia, MO	Bus Stop	2:10 AM	Milwaukee	Central Bus Station	Economy	$77	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/5/2026 8:30:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/6/2026 2:10:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 40m
Greyhound US	15h 30m	10:40 AM	Columbia, MO	Red Thread	2:10 AM	Milwaukee	Central Bus Station	Economy	$77	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/5/2026 10:40:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/6/2026 2:10:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 25m	8:05 PM	Columbia, MO	Bus Stop	8:30 AM	Milwaukee	Central Bus Station	Economy	$77	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/6/2026 8:05:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/7/2026 8:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 25m
Greyhound US	11h 55m	8:35 PM	Columbia, MO	Red Thread	8:30 AM	Milwaukee	Central Bus Station	Economy	$79	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/6/2026 8:35:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/7/2026 8:30:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 11h 55m
Greyhound US	17h 40m	8:30 AM	Columbia, MO	Bus Stop	2:10 AM	Milwaukee	Central Bus Station	Economy	$89	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/6/2026 8:30:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/7/2026 2:10:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 17h 40m
Greyhound US	15h 30m	10:40 AM	Columbia, MO	Red Thread	2:10 AM	Milwaukee	Central Bus Station	Economy	$90	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/6/2026 10:40:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/7/2026 2:10:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 15h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 40m	8:30 AM	Columbia, MO	Bus Stop	2:10 AM	Milwaukee	Central Bus Station	Economy	$74	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/7/2026 8:30:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/8/2026 2:10:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 17h 40m
Greyhound US	12h 25m	8:05 PM	Columbia, MO	Bus Stop	8:30 AM	Milwaukee	Central Bus Station	Economy	$74	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/7/2026 8:05:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/8/2026 8:30:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 12h 25m
Greyhound US	15h 30m	10:40 AM	Columbia, MO	Red Thread	2:10 AM	Milwaukee	Central Bus Station	Economy	$75	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/7/2026 10:40:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/8/2026 2:10:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 15h 30m
Greyhound US	11h 55m	8:35 PM	Columbia, MO	Red Thread	8:30 AM	Milwaukee	Central Bus Station	Economy	$75	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/7/2026 8:35:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/8/2026 8:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 11h 55m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 40m	8:30 AM	Columbia, MO	Bus Stop	2:10 AM	Milwaukee	Central Bus Station	Economy	$78	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/8/2026 8:30:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/9/2026 2:10:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 17h 40m
Greyhound US	15h 30m	10:40 AM	Columbia, MO	Red Thread	2:10 AM	Milwaukee	Central Bus Station	Economy	$79	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/8/2026 10:40:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/9/2026 2:10:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 15h 30m
Greyhound US	11h 55m	8:35 PM	Columbia, MO	Red Thread	8:30 AM	Milwaukee	Central Bus Station	Economy	$79	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/8/2026 8:35:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/9/2026 8:30:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 11h 55m
Greyhound US	12h 25m	8:05 PM	Columbia, MO	Bus Stop	8:30 AM	Milwaukee	Central Bus Station	Economy	$80	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/8/2026 8:05:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/9/2026 8:30:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 12h 25m

Did you know that if you travel from Columbia, MO to Milwaukee via Chicago, you can save more than $8? You can find the corresponding connections below.
- Greyhound US
  
  11h 55m
  
  0
  
  8:35 PM
  
  Columbia, MO
  Red Thread
  
  5:45 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $57
  
  A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/8/2026 8:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/9/2026 5:45:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 10m
- Greyhound US
  
  1h 55m
  
  0
  
  6:35 AM
  
  Chicago
  Downtown Bus Station
  
  8:30 AM
  
  Milwaukee
  Central Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/9/2026 6:35:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/9/2026 8:30:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 1h 55m
Travel time is the same as the direct connection, but you will save $8

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 25m	8:05 PM	Columbia, MO	Bus Stop	8:30 AM	Milwaukee	Central Bus Station	Economy	$73	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/9/2026 8:05:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/10/2026 8:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 25m
Greyhound US	17h 40m	8:30 AM	Columbia, MO	Bus Stop	2:10 AM	Milwaukee	Central Bus Station	Economy	$74	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/9/2026 8:30:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/10/2026 2:10:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 17h 40m
Greyhound US	15h 30m	10:40 AM	Columbia, MO	Red Thread	2:10 AM	Milwaukee	Central Bus Station	Economy	$75	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/9/2026 10:40:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/10/2026 2:10:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 15h 30m
Greyhound US	11h 55m	8:35 PM	Columbia, MO	Red Thread	8:30 AM	Milwaukee	Central Bus Station	Economy	$75	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/9/2026 8:35:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/10/2026 8:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 11h 55m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 40m	8:30 AM	Columbia, MO	Bus Stop	2:10 AM	Milwaukee	Central Bus Station	Economy	$76	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/10/2026 8:30:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/11/2026 2:10:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 17h 40m
Greyhound US	12h 25m	8:05 PM	Columbia, MO	Bus Stop	8:30 AM	Milwaukee	Central Bus Station	Economy	$76	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/10/2026 8:05:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/11/2026 8:30:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 25m
Greyhound US	15h 30m	10:40 AM	Columbia, MO	Red Thread	2:10 AM	Milwaukee	Central Bus Station	Economy	$76	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/10/2026 10:40:00 AM to Central Bus Station, Milwaukee (USA) arriving at 6/11/2026 2:10:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 15h 30m
Greyhound US	11h 55m	8:35 PM	Columbia, MO	Red Thread	8:30 AM	Milwaukee	Central Bus Station	Economy	$76	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/10/2026 8:35:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/11/2026 8:30:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 11h 55m

Did you know that if you travel from Columbia, MO to Milwaukee via Chicago, you can save more than $8? You can find the corresponding connections below.
- Greyhound US
  
  17h 35m
  
  0
  
  8:35 PM
  
  Columbia, MO
  Red Thread
  
  5:45 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $54
  
  A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/10/2026 8:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/11/2026 5:45:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 9h 10m
- FlixBus
  
  2h 10m
  
  0
  
  12:00 PM
  
  Chicago
  Downtown Bus Station
  
  2:10 PM
  
  Milwaukee
  Central Bus Station
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/11/2026 12:00:00 PM to Central Bus Station, Milwaukee (USA) arriving at 6/11/2026 2:10:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 2h 10m
Travel time is 5h 40m longer, but you will save $8

Best Price Offer: The price for the cheapest bus from Columbia, MO to Milwaukee is $67 on 6/11/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Columbia, MO and Milwaukee

See here how frequent the connections between Columbia, MO and Milwaukee are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Columbia, MO to Milwaukee. Monday has instead the fewest connections, with only 4 daily coaches between Columbia, MO and Milwaukee.

The busiest time of the day is the Morning, with 20 buses from Columbia, MO to Milwaukee, while Morning sees the fewest connections between Columbia, MO and Milwaukee, with 20 offers.

Facts about the bus from Columbia, MO to Milwaukee

Compare all providers like Greyhound US that travel 5 times every day by bus from Columbia, MO to Milwaukee in one click! Book your bus ticket from Columbia, MO to Milwaukee starting from $67!

Cheapest Bus	$67
Fastest Bus	11h 55m
Earliest Bus	8:30 AM
Latest Bus	8:35 PM
Daily Bus Routes	5 Ø
Distance	363.8 miles
Bus Companies	Greyhound US

Cheapest bus connections from Columbia, MO to Milwaukee

Every day, 5 buses from 1 bus companies leave Columbia, MO for Milwaukee: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/31

Monday 06/01

Tuesday 06/02

Wednesday 06/03

Thursday 06/04

$77

Friday 06/05

$77

Saturday 06/06

$77

Sunday 06/07

$78

Monday 06/08

$78

Tuesday 06/09

$73

Wednesday 06/10

$76

Thursday 06/11

$67

Friday 06/12

$72

Saturday 06/13

Sunday 06/14

$77

Monday 06/15

Tuesday 06/16

$73

Wednesday 06/17

$77

Thursday 06/18

$79

Friday 06/19

Saturday 06/20

Sunday 06/21

$76

Monday 06/22

$78

Tuesday 06/23

$78

Wednesday 06/24

$88

Thursday 06/25

$78

Friday 06/26

$79

Saturday 06/27

The cheapest time to travel from Columbia, MO to Milwaukee

See here on which day and which time of the day you can find the cheapest bus ticket from Columbia, MO to Milwaukee, for the next 30 days.

With a price starting from $67, Thursday is the cheapest day for a bus from Columbia, MO to Milwaukee. Monday instead is the most expensive day with prices starting from $78.

Evening is the cheapest day time for bus tickets from Columbia, MO to Milwaukee, with $73. Morning is the most expensive time of the day with prices starting from $74.

How to save money travelling from Columbia, MO to Milwaukee

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Columbia, MO to Milwaukee in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Columbia, MO to Milwaukee, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Columbia, MO to Milwaukee are also emptier.

All bus stations and stops in Columbia, MO and Milwaukee

In the map below, you can see where to find all bus stations in Columbia, MO and Milwaukee.

Bus Stop

N 10th St 198

Red Thread

Highway 40 W 6401

University

Fellows Pl 1301-1349

Intermodal Station

W. St Paul's Ave 433

Central Bus Station

4960 S. 13th St. Park

Badger

N James Lovell St 635

Downtown Bus Station

Service and Comfort on the bus from Columbia, MO to Milwaukee

Want to know which seat classes are available on the buses from Columbia, MO to Milwaukee? Or which bus companies serve the route Columbia, MO to Milwaukee? Below you will find answers to your questions.

FAQs about the Columbia, MO to Milwaukee bus

How much does a Columbia, MO Milwaukee bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $67 and takes 11h 55m to reach Milwaukee. Compare offers to save money!

How much could I save by comparing buses from Columbia, MO to Milwaukee?

This route is offered by 1 companies with a range of ticket prices between $67 and $90. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milwaukee.

On average, how many connections are available from Columbia, MO to Milwaukee each day?

Every day, the Columbia, MO to Milwaukee bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Columbia, MO to Milwaukee take?

The fastest bus from Columbia, MO to Milwaukee is offered by Greyhound US and takes 11h 55m. Bus tickets for this connection cost $77. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Columbia, MO to Milwaukee?

The earliest bus arriving in Milwaukee from Columbia, MO starts at 8:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Columbia, MO to Milwaukee?

The latest bus trip departing from Columbia, MO for Milwaukee starts at 8:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Columbia, MO Milwaukee route?

When traveling by bus from Columbia, MO to Milwaukee, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Columbia, MO and Milwaukee?

You can check all the direct connections between Columbia, MO and Milwaukee by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Columbia, MO to Milwaukee bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Columbia, MO Milwaukee bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Columbia, MO Milwaukee bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Columbia, MO to Milwaukee on your planned travel date.

How does CheckMyBus find the best bus deals from Columbia, MO to Milwaukee?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Columbia, MO and Milwaukee. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Columbia, MO to Milwaukee?

Prices and availability for 5 trips between Columbia, MO and Milwaukee change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Columbia, MO to Milwaukee

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Columbia, MO and to Milwaukee

Here’s an overview of the most popular bus routes to Columbia, MO and to Milwaukee. Simply click on the connection of your choice, and you will find all the details about your bus route!