Bus Fort Pierce, FL to Frederick, MD

Compare all timetables for the bus from Fort Pierce, FL to Frederick, MD

Here is a selection of the cheapest bus trips from the schedule from Fort Pierce, FL to Frederick, MD from various bus operators like FlixBus or Greyhound US for the next days.

today

$128

tomorrow

Wednesday

Thursday

Friday

$128

Saturday

Sunday

$144

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	39h 35m	3:05 PM	Fort Pierce, FL	Greyhound Bus Station	6:40 AM	Frederick, MD	Bus Stop		Economy	$128	A Bus from Greyhound US goes from Greyhound Bus Station, Fort Pierce, FL (USA) at 4/20/2026 3:05:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/22/2026 6:40:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 39h 35m
	FlixBus	28h 45m	1:55 AM	Fort Pierce, FL	Okeechobee Road	6:40 AM	Frederick, MD	Bus Stop		Economy	$129	A Bus from FlixBus goes from Okeechobee Road, Fort Pierce, FL (USA) at 4/20/2026 1:55:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/21/2026 6:40:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 28h 45m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	28h 45m	1:55 AM	Fort Pierce, FL	Okeechobee Road	6:40 AM	Frederick, MD	Bus Stop		Economy	$128	A Bus from FlixBus goes from Okeechobee Road, Fort Pierce, FL (USA) at 4/24/2026 1:55:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/25/2026 6:40:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 28h 45m
	Greyhound US	34h 10m	8:30 PM	Fort Pierce, FL	Greyhound Bus Station	6:40 AM	Frederick, MD	Bus Stop		Economy	$134	A Bus from Greyhound US goes from Greyhound Bus Station, Fort Pierce, FL (USA) at 4/24/2026 8:30:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/26/2026 6:40:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 34h 10m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	28h 45m	1:55 AM	Fort Pierce, FL	Okeechobee Road	6:40 AM	Frederick, MD	Bus Stop		Economy	$144	A Bus from FlixBus goes from Okeechobee Road, Fort Pierce, FL (USA) at 4/26/2026 1:55:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/27/2026 6:40:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 28h 45m
	Greyhound US	34h 10m	8:30 PM	Fort Pierce, FL	Greyhound Bus Station	6:40 AM	Frederick, MD	Bus Stop		Economy	$146	A Bus from Greyhound US goes from Greyhound Bus Station, Fort Pierce, FL (USA) at 4/26/2026 8:30:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/28/2026 6:40:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 34h 10m

Did you know that if you travel from Fort Pierce, FL to Frederick, MD via Washington, DC, you can save more than $16? You can find the corresponding connections below.
- FlixBus
  
  40h 25m
  
  0
  
  3:00 AM
  
  Fort Pierce, FL
  Okeechobee Road
  
  10:35 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $120
  
  A Bus from FlixBus goes from Okeechobee Road, Fort Pierce, FL (USA) at 4/21/2026 3:00:00 AM to Union Station, Washington, DC (USA) arriving at 4/22/2026 10:35:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 31h 35m
- Greyhound US
  
  1h 50m
  
  0
  
  5:35 PM
  
  Washington, DC
  Union Station
  
  7:25 PM
  
  Frederick, MD
  Bus Stop
  
  0
  
  Economy
  
  $8
  
  A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 4/22/2026 5:35:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/22/2026 7:25:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 1h 50m
Travel time is 11h 40m longer, but you will save $16

Best Price Offer: The price for the cheapest bus from Fort Pierce, FL to Frederick, MD is $109 on 5/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Fort Pierce, FL and Frederick, MD

See here how frequent the connections between Fort Pierce, FL and Frederick, MD are, during different times and days of the week.

Sunday is the busiest day, with more than 2 daily buses from Fort Pierce, FL to Frederick, MD. Sunday has instead the fewest connections, with only 2 daily coaches between Fort Pierce, FL and Frederick, MD.

The busiest time of the day is the Night, with 3 buses from Fort Pierce, FL to Frederick, MD, while Afternoon sees the fewest connections between Fort Pierce, FL and Frederick, MD, with 1 offers.

Facts about the bus from Fort Pierce, FL to Frederick, MD

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Fort Pierce, FL to Frederick, MD in one click! Book your bus ticket from Fort Pierce, FL to Frederick, MD starting from $109!

Cheapest Bus	$109
Fastest Bus	28h 45m
Earliest Bus	1:55 AM
Latest Bus	8:30 PM
Daily Bus Routes	2 Ø
Distance	844.4 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Fort Pierce, FL to Frederick, MD

Every day, 2 buses from 2 bus companies leave Fort Pierce, FL for Frederick, MD: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$128

Tuesday 04/21

Wednesday 04/22

Thursday 04/23

Friday 04/24

$128

Saturday 04/25

Sunday 04/26

$144

Monday 04/27

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

$120

Friday 05/01

Saturday 05/02

Sunday 05/03

Monday 05/04

$131

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

Sunday 05/10

Monday 05/11

Tuesday 05/12

Wednesday 05/13

Thursday 05/14

$109

Friday 05/15

Saturday 05/16

The cheapest time to travel from Fort Pierce, FL to Frederick, MD

See here on which day and which time of the day you can find the cheapest bus ticket from Fort Pierce, FL to Frederick, MD, for the next 30 days.

With a price starting from $128, Monday is the cheapest day for a bus from Fort Pierce, FL to Frederick, MD. Sunday instead is the most expensive day with prices starting from $144.

Night is the cheapest day time for bus tickets from Fort Pierce, FL to Frederick, MD, with $109. Evening is the most expensive time of the day with prices starting from $134.

How to save money travelling from Fort Pierce, FL to Frederick, MD

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Fort Pierce, FL to Frederick, MD in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Fort Pierce, FL to Frederick, MD, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Fort Pierce, FL to Frederick, MD are also emptier.

Beloved bus companies from Fort Pierce, FL to Frederick, MD

These are the most booked bus companies between Fort Pierce, FL to Frederick, MD from our users.

FlixBus from Fort Pierce, FL to Frederick, MD

Here you will find the key facts about the FlixBus bus route Fort Pierce, FL to Frederick, MD:

Cheapest Price	$128
Fastest Bus	28h 45m
Earliest Bus	1:55 AM
Last Bus	1:55 AM
Daily Connections	1 Ø
Found on	3/27/2026

All bus stations and stops in Fort Pierce, FL and Frederick, MD

In the map below, you can see where to find all bus stations in Fort Pierce, FL and Frederick, MD.

Greyhound Bus Station

Okeechobee Rd 7150

Bus Stop

Okeechobee Road

Okeechobee Road 5151

Juanita Ave

Bus Stop

Se St 100

Prospect Plaza - Dollar tree Bus Stop

Service and Comfort on the bus from Fort Pierce, FL to Frederick, MD

Want to know which seat classes are available on the buses from Fort Pierce, FL to Frederick, MD? Or which bus companies serve the route Fort Pierce, FL to Frederick, MD? Below you will find answers to your questions.

FAQs about the Fort Pierce, FL to Frederick, MD bus

How much does a Fort Pierce, FL Frederick, MD bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $109 and takes 39h 35m to reach Frederick, MD. Compare offers to save money!

How much could I save by comparing buses from Fort Pierce, FL to Frederick, MD?

This route is offered by 2 companies with a range of ticket prices between $109 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Frederick, MD.

On average, how many connections are available from Fort Pierce, FL to Frederick, MD each day?

Every day, the Fort Pierce, FL to Frederick, MD bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Fort Pierce, FL to Frederick, MD take?

The fastest bus from Fort Pierce, FL to Frederick, MD is offered by FlixBus and takes 28h 45m. Bus tickets for this connection cost $129. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Fort Pierce, FL to Frederick, MD?

The earliest bus arriving in Frederick, MD from Fort Pierce, FL starts at 1:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Fort Pierce, FL to Frederick, MD?

The latest bus trip departing from Fort Pierce, FL for Frederick, MD starts at 8:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Fort Pierce, FL Frederick, MD route?

When traveling by bus from Fort Pierce, FL to Frederick, MD, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Fort Pierce, FL and Frederick, MD?

You can check all the direct connections between Fort Pierce, FL and Frederick, MD by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Fort Pierce, FL to Frederick, MD bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Fort Pierce, FL Frederick, MD bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Fort Pierce, FL Frederick, MD bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Fort Pierce, FL to Frederick, MD on your planned travel date.

How does CheckMyBus find the best bus deals from Fort Pierce, FL to Frederick, MD?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Fort Pierce, FL and Frederick, MD. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Fort Pierce, FL to Frederick, MD?

Prices and availability for 2 trips between Fort Pierce, FL and Frederick, MD change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Fort Pierce, FL to Frederick, MD

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Fort Pierce, FL and to Frederick, MD

Here’s an overview of the most popular bus routes to Fort Pierce, FL and to Frederick, MD. Simply click on the connection of your choice, and you will find all the details about your bus route!