Bus Chicago to Frederick, MD - Compare all Companies

Compare all timetables for the bus from Chicago to Frederick, MD

Here is a selection of the cheapest bus trips from the schedule from Chicago to Frederick, MD from various bus operators like Greyhound US or FlixBus for the next days.

today

$73

tomorrow

$73

Wednesday

Thursday

$75

Friday

Saturday

$77

Sunday

$79

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	7:00 AM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$73	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/20/2026 7:00:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/21/2026 12:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 30m
Greyhound US	15h 20m	6:00 PM	Chicago	Downtown Bus Station	10:20 AM	Frederick, MD	Bus Stop	Economy	$73	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/20/2026 6:00:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/21/2026 10:20:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 15h 20m
Greyhound US	23h 55m	11:35 PM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$93	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/20/2026 11:35:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/22/2026 12:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 55m
FlixBus	16h 30m	11:30 AM	Chicago	Downtown Bus Station	5:00 AM	Frederick, MD	Bus Stop	Economy	$94	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/20/2026 11:30:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/21/2026 5:00:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	7:00 AM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$73	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/21/2026 7:00:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/22/2026 12:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 30m
Greyhound US	15h 20m	6:00 PM	Chicago	Downtown Bus Station	10:20 AM	Frederick, MD	Bus Stop	Economy	$75	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/21/2026 6:00:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/22/2026 10:20:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 15h 20m
Greyhound US	23h 55m	11:35 PM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$93	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/21/2026 11:35:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/23/2026 12:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 55m
FlixBus	16h 30m	11:30 AM	Chicago	Downtown Bus Station	5:00 AM	Frederick, MD	Bus Stop	Economy	$94	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/21/2026 11:30:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/22/2026 5:00:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 30m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	7:00 AM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$75	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/23/2026 7:00:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/24/2026 12:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 30m
Greyhound US	15h 20m	6:00 PM	Chicago	Downtown Bus Station	10:20 AM	Frederick, MD	Bus Stop	Economy	$75	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/23/2026 6:00:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/24/2026 10:20:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 15h 20m
Greyhound US	23h 55m	11:35 PM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$93	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/23/2026 11:35:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/25/2026 12:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 55m
FlixBus	16h 30m	11:30 AM	Chicago	Downtown Bus Station	5:00 AM	Frederick, MD	Bus Stop	Economy	$94	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/23/2026 11:30:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/24/2026 5:00:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	7:00 AM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$77	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/25/2026 7:00:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/26/2026 12:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 30m
Greyhound US	15h 20m	6:00 PM	Chicago	Downtown Bus Station	10:20 AM	Frederick, MD	Bus Stop	Economy	$77	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/25/2026 6:00:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/26/2026 10:20:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 20m
Greyhound US	23h 55m	11:35 PM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$93	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/25/2026 11:35:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/27/2026 12:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 55m
FlixBus	16h 30m	11:30 AM	Chicago	Downtown Bus Station	5:00 AM	Frederick, MD	Bus Stop	Economy	$95	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/25/2026 11:30:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/26/2026 5:00:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 16h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	7:00 AM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$79	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/26/2026 7:00:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/27/2026 12:30:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 16h 30m
Greyhound US	15h 20m	6:00 PM	Chicago	Downtown Bus Station	10:20 AM	Frederick, MD	Bus Stop	Economy	$79	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/26/2026 6:00:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/27/2026 10:20:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 15h 20m
Greyhound US	23h 55m	11:35 PM	Chicago	Downtown Bus Station	12:30 AM	Frederick, MD	Bus Stop	Economy	$93	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 4/26/2026 11:35:00 PM to Bus Stop, Frederick, MD (USA) arriving at 4/28/2026 12:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 55m
FlixBus	16h 30m	11:30 AM	Chicago	Downtown Bus Station	5:00 AM	Frederick, MD	Bus Stop	Economy	$94	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 4/26/2026 11:30:00 AM to Bus Stop, Frederick, MD (USA) arriving at 4/27/2026 5:00:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 16h 30m

Best Price Offer: The price for the cheapest bus from Chicago to Frederick, MD is $73 on 4/20/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Frederick, MD

See here how frequent the connections between Chicago and Frederick, MD are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Chicago to Frederick, MD. Sunday has instead the fewest connections, with only 6 daily coaches between Chicago and Frederick, MD.

The busiest time of the day is the Morning, with 15 buses from Chicago to Frederick, MD, while Morning sees the fewest connections between Chicago and Frederick, MD, with 15 offers.

Facts about the bus from Chicago to Frederick, MD

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Chicago to Frederick, MD in one click! Book your bus ticket from Chicago to Frederick, MD starting from $73!

Cheapest Bus	$73
Fastest Bus	16h 20m
Earliest Bus	7:00 AM
Latest Bus	11:35 PM
Daily Bus Routes	6 Ø
Distance	563.7 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Frederick, MD

Every day, 6 buses from 2 bus companies leave Chicago for Frederick, MD: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$73

Tuesday 04/21

$73

Wednesday 04/22

Thursday 04/23

$75

Friday 04/24

Saturday 04/25

$77

Sunday 04/26

$79

Monday 04/27

Tuesday 04/28

$75

Wednesday 04/29

$75

Thursday 04/30

Friday 05/01

$77

Saturday 05/02

Sunday 05/03

Monday 05/04

$81

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

Sunday 05/10

$77

Monday 05/11

$73

Tuesday 05/12

$73

Wednesday 05/13

Thursday 05/14

Friday 05/15

$89

Saturday 05/16

The cheapest time to travel from Chicago to Frederick, MD

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Frederick, MD, for the next 30 days.

With a price starting from $73, Monday is the cheapest day for a bus from Chicago to Frederick, MD. Sunday instead is the most expensive day with prices starting from $77.

Morning is the cheapest day time for bus tickets from Chicago to Frederick, MD, with $73. Morning is the most expensive time of the day with prices starting from $73.

How to save money travelling from Chicago to Frederick, MD

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Frederick, MD in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Frederick, MD, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Frederick, MD are also emptier.

All bus stations and stops in Chicago and Frederick, MD

In the map below, you can see where to find all bus stations in Chicago and Frederick, MD.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Bus Stop

Se St 100

Prospect Plaza - Dollar tree Bus Stop

Service and Comfort on the bus from Chicago to Frederick, MD

Want to know which seat classes are available on the buses from Chicago to Frederick, MD? Or which bus companies serve the route Chicago to Frederick, MD? Below you will find answers to your questions.

FAQs about the Chicago to Frederick, MD bus

How much does a Chicago Frederick, MD bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $73 and takes 17h 30m to reach Frederick, MD. Compare offers to save money!

How much could I save by comparing buses from Chicago to Frederick, MD?

This route is offered by 2 companies with a range of ticket prices between $73 and $101. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Frederick, MD.

On average, how many connections are available from Chicago to Frederick, MD each day?

Every day, the Chicago to Frederick, MD bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Frederick, MD take?

The fastest bus from Chicago to Frederick, MD is offered by Greyhound US and takes 16h 20m. Bus tickets for this connection cost $73. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Frederick, MD?

The earliest bus arriving in Frederick, MD from Chicago starts at 7:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Frederick, MD?

The latest bus trip departing from Chicago for Frederick, MD starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Frederick, MD route?

When traveling by bus from Chicago to Frederick, MD, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Frederick, MD?

You can check all the direct connections between Chicago and Frederick, MD by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Frederick, MD bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Frederick, MD bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Frederick, MD bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Frederick, MD on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to Frederick, MD?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Chicago and Frederick, MD. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to Frederick, MD?

Prices and availability for 6 trips between Chicago and Frederick, MD change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to Frederick, MD

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Frederick, MD

Here’s an overview of the most popular bus routes to Chicago and to Frederick, MD. Simply click on the connection of your choice, and you will find all the details about your bus route!