Compare all timetables for the bus from Frederick, MD to Chicago
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 15h 25m | 7:35 PM | Frederick, MD | Bus Stop | 10:00 AM | Chicago | Downtown Bus Station | Economy | $86 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/19/2026 7:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/20/2026 10:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 15h 25m
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| Greyhound US | 18h 50m | 7:35 PM | Frederick, MD | Bus Stop | 1:25 PM | Chicago | 95th Red Line Station | Economy | $96 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/19/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/20/2026 1:25:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 18h 50m
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| Greyhound US | 22h 40m | 10:20 AM | Frederick, MD | Bus Stop | 8:00 AM | Chicago | Union Station | Economy | $109 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/19/2026 10:20:00 AM to Union Station, Chicago (USA) arriving at 1/20/2026 8:00:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 22h 40m
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| Greyhound US | 23h 5m | 10:20 AM | Frederick, MD | Bus Stop | 8:25 AM | Chicago | Downtown Bus Station | Economy | $109 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/19/2026 10:20:00 AM to Downtown Bus Station, Chicago (USA) arriving at 1/20/2026 8:25:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 5m
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| Greyhound US | 24h 30m | 10:20 AM | Frederick, MD | Bus Stop | 9:50 AM | Chicago | 95th Red Line Station | Economy | $113 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/19/2026 10:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/20/2026 9:50:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 24h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 15h 25m | 7:35 PM | Frederick, MD | Bus Stop | 10:00 AM | Chicago | Downtown Bus Station | Economy | $86 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/20/2026 7:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/21/2026 10:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 15h 25m
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| Greyhound US | 18h 50m | 7:35 PM | Frederick, MD | Bus Stop | 1:25 PM | Chicago | 95th Red Line Station | Economy | $96 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/20/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/21/2026 1:25:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 18h 50m
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| Greyhound US | 27h 55m | 5:05 AM | Frederick, MD | Bus Stop | 8:00 AM | Chicago | Union Station | Economy | $107 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/20/2026 5:05:00 AM to Union Station, Chicago (USA) arriving at 1/21/2026 8:00:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 27h 55m
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| Greyhound US | 28h 20m | 5:05 AM | Frederick, MD | Bus Stop | 8:25 AM | Chicago | Downtown Bus Station | Economy | $107 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/20/2026 5:05:00 AM to Downtown Bus Station, Chicago (USA) arriving at 1/21/2026 8:25:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 28h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 15h 25m | 7:35 PM | Frederick, MD | Bus Stop | 10:00 AM | Chicago | Downtown Bus Station | Economy | $84 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/24/2026 7:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/25/2026 10:00:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 15h 25m
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| Greyhound US | 18h 50m | 7:35 PM | Frederick, MD | Bus Stop | 1:25 PM | Chicago | 95th Red Line Station | Economy | $96 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/24/2026 7:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/25/2026 1:25:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 18h 50m
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| Greyhound US | 20h 20m | 10:20 AM | Frederick, MD | Bus Stop | 5:40 AM | Chicago | 95th Red Line Station | Economy | $102 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/24/2026 10:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/25/2026 5:40:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 20m
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| Greyhound US | 22h 40m | 10:20 AM | Frederick, MD | Bus Stop | 8:00 AM | Chicago | Union Station | Economy | $102 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/24/2026 10:20:00 AM to Union Station, Chicago (USA) arriving at 1/25/2026 8:00:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 40m
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| Greyhound US | 20h 50m | 10:20 AM | Frederick, MD | Bus Stop | 6:10 AM | Chicago | Downtown Bus Station | Economy | $103 |
A Bus from Greyhound US goes from Bus Stop, Frederick, MD (USA) at 1/24/2026 10:20:00 AM to Downtown Bus Station, Chicago (USA) arriving at 1/25/2026 6:10:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 20h 50m
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Best Price Offer: The price for the cheapest bus from Frederick, MD to Chicago is $84 on 1/24/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Frederick, MD and Chicago
Facts about the bus from Frederick, MD to Chicago
Compare all providers like Greyhound US that travel 4 times every day by bus from Frederick, MD to Chicago in one click! Book your bus ticket from Frederick, MD to Chicago starting from $84!
| Cheapest Bus | $84 |
| Fastest Bus | 14h 25m |
| Earliest Bus | 10:20 AM |
| Latest Bus | 7:35 PM |
| Daily Bus Routes | 4 Ø |
| Distance | 563.7 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Frederick, MD to Chicago
Every day, 4 buses from 1 bus companies leave Frederick, MD for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.
The cheapest time to travel from Frederick, MD to Chicago
How to save money travelling from Frederick, MD to Chicago
Book the ticket from Frederick, MD to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frederick, MD to Chicago, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frederick, MD to Chicago are also emptier.All bus stations and stops in Frederick, MD and Chicago
In the map below, you can see where to find all bus stations in Frederick, MD and Chicago.
Service and Comfort on the bus from Frederick, MD to Chicago
FAQs about the Frederick, MD to Chicago bus
How much does a Frederick, MD Chicago bus trip cost?
How much could I save by comparing buses from Frederick, MD to Chicago?
On average, how many connections are available from Frederick, MD to Chicago each day?
How long does a bus journey from Frederick, MD to Chicago take?
What time is the first bus from Frederick, MD to Chicago?
What time is the last bus from Frederick, MD to Chicago?
Which bus companies operate the Frederick, MD Chicago route?
Is there a direct bus between Frederick, MD and Chicago?
What can I take with me on the Frederick, MD to Chicago bus route?
What equipment is available for the Frederick, MD Chicago bus route?
How does CheckMyBus find the best bus deals from Frederick, MD to Chicago?
How does CheckMyBus technology work for trips from Frederick, MD to Chicago?
Available seat classes which are offered on the bus route Frederick, MD to Chicago
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Frederick, MD and to Chicago
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