Bus from Frederick, MD to Chicago from $67

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Compare all timetables for the bus from Frederick, MD to Chicago

Here is a selection of the cheapest bus trips from the schedule from Frederick, MD to Chicago from various bus operators like Greyhound US for the next days.

today
$67
tomorrow
$93
Wednesday
$67
Thursday
Friday
$75
Saturday
Sunday
$75

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $67
Greyhound US 18h 50m 7:35 PM Frederick, MD Bus Stop 1:25 PM Chicago 95th Red Line Station  Economy $89
Greyhound US 22h 35m 10:25 AM Frederick, MD Bus Stop 8:00 AM Chicago Canal & Van Buren  Economy $97
Greyhound US 20h 45m 10:25 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $97
Greyhound US 20h 15m 10:25 AM Frederick, MD Bus Stop 5:40 AM Chicago 95th Red Line Station  Economy $98

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 18h 50m 7:35 PM Frederick, MD Bus Stop 1:25 PM Chicago 95th Red Line Station  Economy $93
Greyhound US 25h 35m 5:05 AM Frederick, MD Bus Stop 5:40 AM Chicago 95th Red Line Station  Economy $107
  • Did you know that if you travel from Frederick, MD to Chicago via Washington, DC, you can save more than $17? You can find the corresponding connections below.
    • Greyhound US
      24h 35m
      0
      10:25 AM
      Frederick, MD
      Bus Stop
      11:35 AM
      Washington, DC
      Union Station
      0
      Greyhound US
      Economy
      $10
      • Waiting Time 6h 0m
    • Greyhound US
      17h 25m
      0
      5:35 PM
      Washington, DC
      Union Station
      10:00 AM
      Chicago
      Downtown Bus Station
      0
      Greyhound US
      Economy
      $66
    Travel time is 6h 45m longer, but you will save $17

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $67
Greyhound US 18h 50m 7:35 PM Frederick, MD Bus Stop 1:25 PM Chicago 95th Red Line Station  Economy $89
Greyhound US 25h 35m 5:05 AM Frederick, MD Bus Stop 5:40 AM Chicago 95th Red Line Station  Economy $103
Greyhound US 27h 55m 5:05 AM Frederick, MD Bus Stop 8:00 AM Chicago Canal & Van Buren  Economy $103
Greyhound US 26h 5m 5:05 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $103

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $75
Greyhound US 22h 35m 10:25 AM Frederick, MD Bus Stop 8:00 AM Chicago Union Station  Economy $101
Greyhound US 20h 45m 10:25 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $101

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 25m 7:35 PM Frederick, MD Bus Stop 10:00 AM Chicago Downtown Bus Station  Economy $75
Greyhound US 18h 50m 7:35 PM Frederick, MD Bus Stop 1:25 PM Chicago 95th Red Line Station  Economy $93
Greyhound US 22h 35m 10:25 AM Frederick, MD Bus Stop 8:00 AM Chicago Union Station  Economy $101
Greyhound US 20h 45m 10:25 AM Frederick, MD Bus Stop 6:10 AM Chicago Downtown Bus Station  Economy $101
Greyhound US 20h 15m 10:25 AM Frederick, MD Bus Stop 5:40 AM Chicago 95th Red Line Station  Economy $102

Best Price Offer: The price for the cheapest bus from Frederick, MD to Chicago is $67 on 5/5/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Frederick, MD and Chicago

See here how frequent the connections between Frederick, MD and Chicago are, during different times and days of the week.
Wednesday is the busiest day, with more than 10 daily buses from Frederick, MD to Chicago. Tuesday has instead the fewest connections, with only 2 daily coaches between Frederick, MD and Chicago.
The busiest time of the day is the Evening, with 11 buses from Frederick, MD to Chicago, while Night sees the fewest connections between Frederick, MD and Chicago, with 7 offers.

Facts about the bus from Frederick, MD to Chicago

Compare all providers like Greyhound US that travel 5 times every day by bus from Frederick, MD to Chicago in one click! Book your bus ticket from Frederick, MD to Chicago starting from $67!

Cheapest Bus $67
Fastest Bus 14h 25m
Earliest Bus 10:25 AM
Latest Bus 7:35 PM
Daily Bus Routes 5 Ø
Distance 563.7 miles
Bus Companies Greyhound US

Cheapest bus connections from Frederick, MD to Chicago

Every day, 5 buses from 1 bus companies leave Frederick, MD for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/19
Monday 04/20
$71
Tuesday 04/21
$93
Wednesday 04/22
$71
Thursday 04/23
Friday 04/24
$75
Saturday 04/25
Sunday 04/26
$75
Monday 04/27
Tuesday 04/28
$73
Wednesday 04/29
$93
Thursday 04/30
$93
Friday 05/01
$79
Saturday 05/02
$79
Sunday 05/03
$107
Monday 05/04
$73
Tuesday 05/05
$67
Wednesday 05/06
Thursday 05/07
Friday 05/08
$75
Saturday 05/09
Sunday 05/10
$71
Monday 05/11
$67
Tuesday 05/12
Wednesday 05/13
Thursday 05/14
$69
Friday 05/15
$89
Saturday 05/16

The cheapest time to travel from Frederick, MD to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Frederick, MD to Chicago, for the next 30 days.
With a price starting from $67, Monday is the cheapest day for a bus from Frederick, MD to Chicago. Friday instead is the most expensive day with prices starting from $75.
Evening is the cheapest day time for bus tickets from Frederick, MD to Chicago, with $67. Morning is the most expensive time of the day with prices starting from $97.

How to save money travelling from Frederick, MD to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Frederick, MD to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Frederick, MD to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Frederick, MD to Chicago are also emptier.

All bus stations and stops in Frederick, MD and Chicago

In the map below, you can see where to find all bus stations in Frederick, MD and Chicago.

Service and Comfort on the bus from Frederick, MD to Chicago

Want to know which seat classes are available on the buses from Frederick, MD to Chicago? Or which bus companies serve the route Frederick, MD to Chicago? Below you will find answers to your questions.

FAQs about the Frederick, MD to Chicago bus

How much does a Frederick, MD Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $67 and takes 14h 25m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Frederick, MD to Chicago?

This route is offered by 1 companies with a range of ticket prices between $67 and $107. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Frederick, MD to Chicago each day?

Every day, the Frederick, MD to Chicago bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Frederick, MD to Chicago take?

The fastest bus from Frederick, MD to Chicago is offered by Greyhound US and takes 14h 25m. Bus tickets for this connection cost $67. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Frederick, MD to Chicago?

The earliest bus arriving in Chicago from Frederick, MD starts at 10:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Frederick, MD to Chicago?

The latest bus trip departing from Frederick, MD for Chicago starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Frederick, MD Chicago route?

When traveling by bus from Frederick, MD to Chicago, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Frederick, MD and Chicago?

You can check all the direct connections between Frederick, MD and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Frederick, MD to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Frederick, MD Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Frederick, MD Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Frederick, MD to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Frederick, MD to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Frederick, MD and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Frederick, MD to Chicago?

Prices and availability for 5 trips between Frederick, MD and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Frederick, MD to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Frederick, MD and to Chicago

Here’s an overview of the most popular bus routes to Frederick, MD and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Fort Pierce, FL - Frederick, MD Bus Fort Pierce, FL - Frederick, MD
Bus Roanoke, VA - Frederick, MD Bus Roanoke, VA - Frederick, MD
Albany, NY to Frederick, MD bus Albany, NY to Frederick, MD bus
Bus to Frederick, MD from Statesville, NC Bus to Frederick, MD from Statesville, NC
Buses London, ON to Chicago Buses London, ON to Chicago
Bus to Chicago from Jackson, TN Bus to Chicago from Jackson, TN
Buses Ciudad Juárez - Chicago Buses Ciudad Juárez - Chicago
Bus Niagara Falls, ON to Chicago Bus Niagara Falls, ON to Chicago
Popular Airport Shuttles to Frederick, MD and to Chicago
CheckMyBus › Buses in USA › Bus to Frederick, MD › Bus to Chicago

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