Bus McAllen, TX to Louisville, KY: Compare prices and save money

Compare all timetables for the bus from McAllen, TX to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from McAllen, TX to Louisville, KY from various bus operators like FlixBus, Valley Transit or Greyhound US for the next days.

today

$123

tomorrow

$141

Wednesday

$154

Thursday

$128

Friday

$137

Saturday

$158

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	30h 35m	6:35 AM	McAllen, TX	Central Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$123	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/20/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/21/2026 2:10:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 30h 35m
Valley Transit	33h 20m	11:15 PM	McAllen, TX	Central Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$123	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/20/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/22/2026 9:35:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 33h 20m
Greyhound US	34h 10m	2:20 PM	McAllen, TX	Central Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$123	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 4/20/2026 2:20:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/22/2026 1:30:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 34h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	33h 20m	11:15 PM	McAllen, TX	Central Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$141	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/21/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/23/2026 9:35:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 33h 20m
Valley Transit	30h 35m	6:35 AM	McAllen, TX	Central Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$142	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/21/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/22/2026 2:10:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 30h 35m
Greyhound Lines Mexico	37h 10m	11:20 AM	McAllen, TX	Central Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$143	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 4/21/2026 11:20:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/23/2026 1:30:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 37h 10m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	30h 35m	6:35 AM	McAllen, TX	Central Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$154	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/22/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/23/2026 2:10:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 30h 35m
Valley Transit	32h 25m	4:05 PM	McAllen, TX	Central Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$154	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/22/2026 4:05:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/24/2026 1:30:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 32h 25m
Valley Transit	33h 20m	11:15 PM	McAllen, TX	Central Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$154	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/22/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/24/2026 9:35:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 33h 20m

Did you know that if you travel from McAllen, TX to Louisville, KY via Reynosa, you can save more than $17? You can find the corresponding connections below.
- Greyhound Lines Mexico
  
  41h 5m
  
  0
  
  3:30 PM
  
  McAllen, TX
  Central Bus Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 4/21/2026 3:30:00 PM to Hotel City Express, Reynosa (Mexico) arriving at 4/21/2026 5:00:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 30m
- Greyhound Lines Mexico
  
  39h 5m
  
  0
  
  5:30 PM
  
  Reynosa
  Hotel City Express
  
  9:35 AM
  
  Louisville, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $130
  
  A Bus from Greyhound Lines Mexico goes from Hotel City Express, Reynosa (Mexico) at 4/21/2026 5:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/23/2026 9:35:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 39h 5m
Travel time is 9h 30m longer, but you will save $17

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	30h 35m	6:35 AM	McAllen, TX	Central Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$128	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/23/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/24/2026 2:10:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 30h 35m
Valley Transit	32h 25m	4:05 PM	McAllen, TX	Central Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$128	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/23/2026 4:05:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/25/2026 1:30:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 32h 25m
Valley Transit	33h 20m	11:15 PM	McAllen, TX	Central Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$128	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 4/23/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/25/2026 9:35:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 33h 20m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 35m	6:35 AM	McAllen, TX	Central Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$137	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 4/24/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/25/2026 2:10:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 30h 35m
FlixBus	32h 25m	4:05 PM	McAllen, TX	Central Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$137	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 4/24/2026 4:05:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/26/2026 1:30:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 32h 25m
FlixBus	33h 20m	11:15 PM	McAllen, TX	Central Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$137	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 4/24/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/26/2026 9:35:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 33h 20m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 35m	6:35 AM	McAllen, TX	Central Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$158	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 4/25/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/26/2026 2:10:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 30h 35m
FlixBus	32h 25m	4:05 PM	McAllen, TX	Central Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$158	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 4/25/2026 4:05:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/27/2026 1:30:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 32h 25m
FlixBus	33h 20m	11:15 PM	McAllen, TX	Central Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$158	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 4/25/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/27/2026 9:35:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 33h 20m

Did you know that if you travel from McAllen, TX to Louisville, KY via Reynosa, you can save more than $21? You can find the corresponding connections below.
- Greyhound Lines Mexico
  
  41h 5m
  
  0
  
  3:30 PM
  
  McAllen, TX
  Central Bus Station
  
  5:00 PM
  
  Reynosa
  Hotel City Express
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 4/21/2026 3:30:00 PM to Hotel City Express, Reynosa (Mexico) arriving at 4/21/2026 5:00:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 30m
- Greyhound Lines Mexico
  
  39h 5m
  
  0
  
  5:30 PM
  
  Reynosa
  Hotel City Express
  
  9:35 AM
  
  Louisville, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $130
  
  A Bus from Greyhound Lines Mexico goes from Hotel City Express, Reynosa (Mexico) at 4/21/2026 5:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 4/23/2026 9:35:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 39h 5m
Travel time is 9h 30m longer, but you will save $21

Best Price Offer: The price for the cheapest bus from McAllen, TX to Louisville, KY is $114 on 5/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between McAllen, TX and Louisville, KY

See here how frequent the connections between McAllen, TX and Louisville, KY are, during different times and days of the week.

Monday is the busiest day, with more than 6 daily buses from McAllen, TX to Louisville, KY. Tuesday has instead the fewest connections, with only 3 daily coaches between McAllen, TX and Louisville, KY.

The busiest time of the day is the Morning, with 10 buses from McAllen, TX to Louisville, KY, while Afternoon sees the fewest connections between McAllen, TX and Louisville, KY, with 8 offers.

Facts about the bus from McAllen, TX to Louisville, KY

Compare all providers like FlixBus, Valley Transit and Greyhound US that travel 4 times every day by bus from McAllen, TX to Louisville, KY in one click! Book your bus ticket from McAllen, TX to Louisville, KY starting from $114!

Cheapest Bus	$114
Fastest Bus	31h 35m
Earliest Bus	6:35 AM
Latest Bus	11:15 PM
Daily Bus Routes	4 Ø
Distance	1,104.6 miles
Bus Companies	FlixBus, Valley Transit, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from McAllen, TX to Louisville, KY

Every day, 4 buses from 4 bus companies leave McAllen, TX for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$127

Tuesday 04/21

$141

Wednesday 04/22

$158

Thursday 04/23

$132

Friday 04/24

$137

Saturday 04/25

$158

Sunday 04/26

Monday 04/27

$125

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

$126

Friday 05/01

$117

Saturday 05/02

$143

Sunday 05/03

$121

Monday 05/04

$114

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$116

Saturday 05/09

$124

Sunday 05/10

$114

Monday 05/11

Tuesday 05/12

Wednesday 05/13

Thursday 05/14

$116

Friday 05/15

$114

Saturday 05/16

The cheapest time to travel from McAllen, TX to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from McAllen, TX to Louisville, KY, for the next 30 days.

With a price starting from $114, Monday is the cheapest day for a bus from McAllen, TX to Louisville, KY. Wednesday instead is the most expensive day with prices starting from $154.

Morning is the cheapest day time for bus tickets from McAllen, TX to Louisville, KY, with $123. Afternoon is the most expensive time of the day with prices starting from $123.

How to save money travelling from McAllen, TX to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from McAllen, TX to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from McAllen, TX to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from McAllen, TX to Louisville, KY are also emptier.

All bus stations and stops in McAllen, TX and Louisville, KY

In the map below, you can see where to find all bus stations in McAllen, TX and Louisville, KY.

Central Bus Station

U.S. 83 Business 1501

Frontera México-USA

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Service and Comfort on the bus from McAllen, TX to Louisville, KY

Want to know which seat classes are available on the buses from McAllen, TX to Louisville, KY? Or which bus companies serve the route McAllen, TX to Louisville, KY? Below you will find answers to your questions.

FAQs about the McAllen, TX to Louisville, KY bus

How much does a McAllen, TX Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $114 and takes 31h 35m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from McAllen, TX to Louisville, KY?

This route is offered by 4 companies with a range of ticket prices between $114 and $158. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from McAllen, TX to Louisville, KY each day?

Every day, the McAllen, TX to Louisville, KY bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from McAllen, TX to Louisville, KY take?

The fastest bus from McAllen, TX to Louisville, KY is offered by Valley Transit and takes 31h 35m. Bus tickets for this connection cost $123. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from McAllen, TX to Louisville, KY?

The earliest bus arriving in Louisville, KY from McAllen, TX starts at 6:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from McAllen, TX to Louisville, KY?

The latest bus trip departing from McAllen, TX for Louisville, KY starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the McAllen, TX Louisville, KY route?

When traveling by bus from McAllen, TX to Louisville, KY, passengers can travel with FlixBus, Valley Transit and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between McAllen, TX and Louisville, KY?

You can check all the direct connections between McAllen, TX and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Valley Transit and Greyhound US.

What can I take with me on the McAllen, TX to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the McAllen, TX Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the McAllen, TX Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from McAllen, TX to Louisville, KY on your planned travel date.

How does CheckMyBus find the best bus deals from McAllen, TX to Louisville, KY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between McAllen, TX and Louisville, KY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from McAllen, TX to Louisville, KY?

Prices and availability for 4 trips between McAllen, TX and Louisville, KY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route McAllen, TX to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to McAllen, TX and to Louisville, KY

Here’s an overview of the most popular bus routes to McAllen, TX and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!