Bus from Opelika, AL to Gainesville, FL from $58

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Opelika, AL to Gainesville, FL

Here is a selection of the cheapest bus trips from the schedule from Opelika, AL to Gainesville, FL from various bus operators like Greyhound US for the next days.

today
tomorrow
$77
Wednesday
$75
Thursday
Friday
$69
Saturday
$59
Sunday
$68

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 30m 4:10 PM Opelika, AL Bus Stop 3:40 AM Gainesville, FL Rosa Parks Transfer station  Economy $77
Greyhound US 14h 30m 9:00 AM Opelika, AL Bus Stop 12:30 AM Gainesville, FL Greyhound Bus Station  Economy $78
Greyhound US 11h 0m 5:15 PM Opelika, AL Bus Stop 5:15 AM Gainesville, FL Rosa Parks Transfer station  Economy $78
  • Did you know that if you travel from Opelika, AL to Gainesville, FL via Atlanta, GA, you can save more than $16? You can find the corresponding connections below.
    • Greyhound US
      10h 30m
      0
      4:10 PM
      Opelika, AL
      Bus Stop
      8:10 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 1h 20m
    • FlixBus
      6h 10m
      0
      9:30 PM
      Atlanta, GA
      Garnett Transit Station
      3:40 AM
      Gainesville, FL
      Rosa Parks Transfer station
      0
      FlixBus
      Economy
      $40
    Travel Time is 1h 0m shorter, and you will save $16

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 11h 0m 5:15 PM Opelika, AL Bus Stop 5:15 AM Gainesville, FL Rosa Parks Transfer station  Economy $75
Greyhound US 10h 30m 4:10 PM Opelika, AL Bus Stop 3:40 AM Gainesville, FL Rosa Parks Transfer station  Economy $76
Greyhound US 14h 30m 9:00 AM Opelika, AL Bus Stop 12:30 AM Gainesville, FL North Walmart Supercenter Bus Stop  Economy $77
  • Did you know that if you travel from Opelika, AL to Gainesville, FL via Atlanta, GA, you can save more than $14? You can find the corresponding connections below.
    • Greyhound US
      10h 30m
      0
      4:10 PM
      Opelika, AL
      Bus Stop
      8:10 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 1h 20m
    • FlixBus
      6h 10m
      0
      9:30 PM
      Atlanta, GA
      Garnett Transit Station
      3:40 AM
      Gainesville, FL
      Rosa Parks Transfer station
      0
      FlixBus
      Economy
      $40
    Travel Time is 1h 0m shorter, and you will save $14

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 11h 0m 5:15 PM Opelika, AL Bus Stop 5:15 AM Gainesville, FL Rosa Parks Transfer station  Economy $69
Greyhound US 14h 30m 9:00 AM Opelika, AL Bus Stop 12:30 AM Gainesville, FL Greyhound Bus Station  Economy $70
Greyhound US 10h 30m 4:10 PM Opelika, AL Bus Stop 3:40 AM Gainesville, FL Rosa Parks Transfer station  Economy $70
  • Did you know that if you travel from Opelika, AL to Gainesville, FL via Atlanta, GA, you can save more than $8? You can find the corresponding connections below.
    • Greyhound US
      10h 30m
      0
      4:10 PM
      Opelika, AL
      Bus Stop
      8:10 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 1h 20m
    • FlixBus
      6h 10m
      0
      9:30 PM
      Atlanta, GA
      Garnett Transit Station
      3:40 AM
      Gainesville, FL
      Rosa Parks Transfer station
      0
      FlixBus
      Economy
      $40
    Travel Time is 1h 0m shorter, and you will save $8

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 30m 9:00 AM Opelika, AL Bus Stop 12:30 AM Gainesville, FL North Walmart Supercenter Bus Stop  Economy $59
Greyhound US 10h 30m 4:10 PM Opelika, AL Bus Stop 3:40 AM Gainesville, FL Rosa Parks Transfer station  Economy $60
Greyhound US 11h 0m 5:15 PM Opelika, AL Bus Stop 5:15 AM Gainesville, FL Rosa Parks Transfer station  Economy $60

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 30m 4:10 PM Opelika, AL Bus Stop 3:40 AM Gainesville, FL Rosa Parks Transfer station  Economy $68
Greyhound US 14h 30m 9:00 AM Opelika, AL Bus Stop 12:30 AM Gainesville, FL Greyhound Bus Station  Economy $69
Greyhound US 11h 0m 5:15 PM Opelika, AL Bus Stop 5:15 AM Gainesville, FL Rosa Parks Transfer station  Economy $69
  • Did you know that if you travel from Opelika, AL to Gainesville, FL via Atlanta, GA, you can save more than $7? You can find the corresponding connections below.
    • Greyhound US
      10h 30m
      0
      4:10 PM
      Opelika, AL
      Bus Stop
      8:10 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 1h 20m
    • FlixBus
      6h 10m
      0
      9:30 PM
      Atlanta, GA
      Garnett Transit Station
      3:40 AM
      Gainesville, FL
      Rosa Parks Transfer station
      0
      FlixBus
      Economy
      $40
    Travel Time is 1h 0m shorter, and you will save $7

Best Price Offer: The price for the cheapest bus from Opelika, AL to Gainesville, FL is $58 on 4/30/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Opelika, AL and Gainesville, FL

See here how frequent the connections between Opelika, AL and Gainesville, FL are, during different times and days of the week.
Sunday is the busiest day, with more than 3 daily buses from Opelika, AL to Gainesville, FL. Sunday has instead the fewest connections, with only 3 daily coaches between Opelika, AL and Gainesville, FL.
The busiest time of the day is the Afternoon, with 10 buses from Opelika, AL to Gainesville, FL, while Morning sees the fewest connections between Opelika, AL and Gainesville, FL, with 5 offers.

Facts about the bus from Opelika, AL to Gainesville, FL

Compare all providers like Greyhound US that travel 3 times every day by bus from Opelika, AL to Gainesville, FL in one click! Book your bus ticket from Opelika, AL to Gainesville, FL starting from $58!

Cheapest Bus $58
Fastest Bus 11h 30m
Earliest Bus 9:00 AM
Latest Bus 5:15 PM
Daily Bus Routes 3 Ø
Distance 275.0 miles
Bus Companies Greyhound US

Cheapest bus connections from Opelika, AL to Gainesville, FL

Every day, 3 buses from 1 bus companies leave Opelika, AL for Gainesville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/19
Monday 04/20
Tuesday 04/21
$77
Wednesday 04/22
$75
Thursday 04/23
Friday 04/24
$69
Saturday 04/25
$59
Sunday 04/26
$68
Monday 04/27
Tuesday 04/28
$79
Wednesday 04/29
$68
Thursday 04/30
$58
Friday 05/01
$63
Saturday 05/02
Sunday 05/03
$58
Monday 05/04
Tuesday 05/05
$70
Wednesday 05/06
Thursday 05/07
Friday 05/08
$70
Saturday 05/09
$68
Sunday 05/10
$66
Monday 05/11
$69
Tuesday 05/12
$69
Wednesday 05/13
$71
Thursday 05/14
$67
Friday 05/15
$68
Saturday 05/16

The cheapest time to travel from Opelika, AL to Gainesville, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Opelika, AL to Gainesville, FL, for the next 30 days.
With a price starting from $58, Sunday is the cheapest day for a bus from Opelika, AL to Gainesville, FL. Tuesday instead is the most expensive day with prices starting from $69.
Morning is the cheapest day time for bus tickets from Opelika, AL to Gainesville, FL, with $59. Afternoon is the most expensive time of the day with prices starting from $60.

How to save money travelling from Opelika, AL to Gainesville, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Opelika, AL to Gainesville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Opelika, AL to Gainesville, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Opelika, AL to Gainesville, FL are also emptier.

All bus stations and stops in Opelika, AL and Gainesville, FL

In the map below, you can see where to find all bus stations in Opelika, AL and Gainesville, FL.

Service and Comfort on the bus from Opelika, AL to Gainesville, FL

Want to know which seat classes are available on the buses from Opelika, AL to Gainesville, FL? Or which bus companies serve the route Opelika, AL to Gainesville, FL? Below you will find answers to your questions.

FAQs about the Opelika, AL to Gainesville, FL bus

How much does a Opelika, AL Gainesville, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $58 and takes 15h 30m to reach Gainesville, FL. Compare offers to save money!

How much could I save by comparing buses from Opelika, AL to Gainesville, FL?

This route is offered by 1 companies with a range of ticket prices between $58 and $78. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Gainesville, FL.

On average, how many connections are available from Opelika, AL to Gainesville, FL each day?

Every day, the Opelika, AL to Gainesville, FL bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Opelika, AL to Gainesville, FL take?

The fastest bus from Opelika, AL to Gainesville, FL is offered by Greyhound US and takes 11h 30m. Bus tickets for this connection cost $77. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Opelika, AL to Gainesville, FL?

The earliest bus arriving in Gainesville, FL from Opelika, AL starts at 9:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Opelika, AL to Gainesville, FL?

The latest bus trip departing from Opelika, AL for Gainesville, FL starts at 5:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Opelika, AL Gainesville, FL route?

When traveling by bus from Opelika, AL to Gainesville, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Opelika, AL and Gainesville, FL?

You can check all the direct connections between Opelika, AL and Gainesville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Opelika, AL to Gainesville, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Opelika, AL Gainesville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Opelika, AL Gainesville, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Opelika, AL to Gainesville, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Opelika, AL to Gainesville, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Opelika, AL and Gainesville, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Opelika, AL to Gainesville, FL?

Prices and availability for 3 trips between Opelika, AL and Gainesville, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Opelika, AL to Gainesville, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Opelika, AL and to Gainesville, FL

Here’s an overview of the most popular bus routes to Opelika, AL and to Gainesville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Savannah, GA to Opelika, AL Bus Savannah, GA to Opelika, AL
Buses Houston - Opelika, AL Buses Houston - Opelika, AL
Buses from Morelia to Opelika, AL Buses from Morelia to Opelika, AL
Buses Montgomery, AL to Opelika, AL Buses Montgomery, AL to Opelika, AL
Anniston, AL to Gainesville, FL bus Anniston, AL to Gainesville, FL bus
Bus Rockledge, FL - Gainesville, FL Bus Rockledge, FL - Gainesville, FL
Buses Biloxi, MS - Gainesville, FL Buses Biloxi, MS - Gainesville, FL
Bus Macon, GA - Gainesville, FL Bus Macon, GA - Gainesville, FL
Popular Airport Shuttles to Opelika, AL and to Gainesville, FL
CheckMyBus › Buses in USA › Bus to Opelika, AL › Bus to Gainesville, FL

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.