Bus from Prague to Odesa from $50

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Compare all timetables for the bus from Prague to Odesa

Here is a selection of the cheapest bus trips from the schedule from Prague to Odesa from various bus operators like FlixBus, Openline or Like Bus for the next days.
today
from $76
tomorrow
from $76
Tuesday
from $76
Wednesday
Thursday
from $76
Friday
from $76
Saturday
from $50

Cheapest bus trips today

Prices are for one way and one person
  • Openline
    30h 30m
    0
    8:50 AM
    Prague
    ÚAN Florenc
    3:20 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $76
  • Openline
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $81
  • Like Bus
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Like Bus
    Economy
    $81

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Openline
    30h 30m
    0
    8:50 AM
    Prague
    ÚAN Florenc
    3:20 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $76
  • Openline
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $81
  • Like Bus
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Like Bus
    Economy
    $81
  • FlixBus
    35h 15m
    0
    5:55 AM
    Prague
    ÚAN Florenc
    5:10 PM
    Odesa
    Central Bus Station
    0
    FlixBus
    Economy
    $93
  • KLR Bus
    34h 0m
    0
    7:00 PM
    Prague
    Train station Wilsonova
    5:00 AM
    Odesa
    Central Bus Station
    0
    KLR Bus
    Economy
    $93

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Openline
    30h 30m
    0
    8:50 AM
    Prague
    ÚAN Florenc
    3:20 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $76
  • Openline
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $81
  • Like Bus
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Like Bus
    Economy
    $81
  • FlixBus
    35h 15m
    0
    5:55 AM
    Prague
    ÚAN Florenc
    5:10 PM
    Odesa
    Central Bus Station
    0
    FlixBus
    Economy
    $89
  • KLR Bus
    34h 0m
    0
    7:00 PM
    Prague
    Train station Wilsonova
    5:00 AM
    Odesa
    Central Bus Station
    0
    KLR Bus
    Economy
    $93

Cheapest bus trips Thursday

Prices are for one way and one person
  • Openline
    30h 30m
    0
    8:50 AM
    Prague
    ÚAN Florenc
    3:20 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $76
  • Openline
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $81
  • Like Bus
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Like Bus
    Economy
    $81
  • FlixBus
    43h 5m
    0
    12:20 AM
    Prague
    Černý Most
    7:25 PM
    Odesa
    Central Bus Station
    0
    FlixBus
    Economy
    $89
  • FlixBus
    37h 35m
    0
    5:50 AM
    Prague
    Wilsonova Bus Station
    7:25 PM
    Odesa
    Central Bus Station
    0
    FlixBus
    Economy
    $89

Cheapest bus trips Friday

Prices are for one way and one person
  • Openline
    30h 30m
    0
    8:50 AM
    Prague
    ÚAN Florenc
    3:20 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $76
  • Openline
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $81
  • Like Bus
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Like Bus
    Economy
    $81

Cheapest bus trips Saturday

Prices are for one way and one person
  • East West Eurolines
    31h 40m
    0
    2:00 PM
    Prague
    ÚAN Florenc
    9:40 PM
    Odesa
    Central Bus Station
    0
    East West Eurolines
    Economy
    $50
  • Lux Bus
    27h 10m
    0
    10:50 AM
    Prague
    ÚAN Florenc
    2:00 PM
    Odesa
    Central Bus Station
    0
    Lux Bus
    Economy
    $66
  • СТЕЦИК Т.В. ФОП
    31h 50m
    0
    1:20 PM
    Prague
    ÚAN Florenc
    9:10 PM
    Odesa
    Central Bus Station
    0
    СТЕЦИК Т.В. ФОП
    Economy
    $67
  • Openline
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Openline
    Economy
    $81
  • Like Bus
    29h 40m
    0
    8:50 AM
    Prague
    Train station Wilsonova
    2:30 PM
    Odesa
    Central Bus Station
    0
    Like Bus
    Economy
    $81

Frequency of bus connections between Prague and Odesa

See here how frequent the connections between Prague and Odesa are, during different times and days of the week.
Saturday is the busiest day, with more than 25 daily buses from Prague to Odesa. Sunday has instead the fewest connections, with only 3 daily coaches between Prague and Odesa.
The busiest time of the day is the Morning, with 32 buses from Prague to Odesa, while Afternoon sees the fewest connections between Prague and Odesa, with 2 offers.

Facts about the bus from Prague to Odesa

Compare all providers like FlixBus, Openline and Like Bus that travel 9 times every day by bus from Prague to Odesa in one click! Book your bus ticket from Prague to Odesa starting from $50!

Cheapest Bus $50
Fastest Bus 27h 10m
Earliest Bus 8:50 AM
Latest Bus 11:25 PM
Daily Bus Routes 9 Ø
Distance 787.3 miles
Bus Companies FlixBus, Openline, Like Bus, KLR Bus, ECOLINES, Musil Tour, Lux Bus, СТЕЦИК Т.В. ФОП and East West Eurolines

Cheapest bus connections from Prague to Odesa

Every day, 9 buses from 9 bus companies leave Prague for Odesa: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
$81
Monday 06/23
$81
Tuesday 06/24
$89
Wednesday 06/25
Thursday 06/26
$76
Friday 06/27
$81
Saturday 06/28
$50
Sunday 06/29
$81
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
Friday 07/04
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12
Sunday 07/13
Monday 07/14
Tuesday 07/15
Wednesday 07/16
Thursday 07/17
Friday 07/18
Saturday 07/19

The cheapest time to travel from Prague to Odesa

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Odesa, for the next 30 days.
With a price starting from $50, Saturday is the cheapest day for a bus from Prague to Odesa. Sunday instead is the most expensive day with prices starting from $76.
Afternoon is the cheapest day time for bus tickets from Prague to Odesa, with $50. Evening is the most expensive time of the day with prices starting from $90.

How to save money travelling from Prague to Odesa

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Odesa in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Odesa, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Odesa are also emptier.

Beloved bus companies from Prague to Odesa

These are the most booked bus companies between Prague to Odesa from our users.

Openline from Prague to Odesa

Openline

Here you will find the key facts about the Openline bus route Prague to Odesa:

Cheapest Price $76
Fastest Bus 29h 40m
Earliest Bus 8:50 AM
Last Bus 8:50 AM
Daily Connections 2 Ø
Found on 6/19/2025

All bus stations and stops in Prague and Odesa

In the map below, you can see where to find all bus stations in Prague and Odesa.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Odesa? Compare all modes of transports from Prague to Odesa.

Service and Comfort on the bus from Prague to Odesa

Want to know which seat classes are available on the buses from Prague to Odesa? Or which bus companies serve the route Prague to Odesa? Below you will find answers to your questions.

FAQs about the Prague to Odesa bus

How much does a Prague Odesa bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $50 and takes 31h 40m to reach Odesa. Compare offers to save money!

How much could I save by comparing buses from Prague to Odesa?

This route is offered by 9 companies with a range of ticket prices between $50 and $135. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Odesa.

On average, how many connections are available from Prague to Odesa each day?

Every day, the Prague to Odesa bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Odesa take?

The fastest bus from Prague to Odesa is offered by Lux Bus and takes 27h 10m. Bus tickets for this connection cost $66. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Odesa?

The earliest bus arriving in Odesa from Prague starts at 8:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Odesa?

The latest bus trip departing from Prague for Odesa starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Odesa route?

When traveling by bus from Prague to Odesa, passengers can travel with FlixBus, Openline and Like Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Odesa?

You can check all the direct connections between Prague and Odesa by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Openline and Like Bus.

What can I take with me on the Prague to Odesa bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Odesa bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Odesa bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Odesa on your planned travel date.

Available seat classes which are offered on the bus route Prague to Odesa

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Odesa

Here’s an overview of the most popular bus routes to Prague and to Odesa. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Paris to Prague bus Paris to Prague bus
From Warsaw to Prague bus From Warsaw to Prague bus
Bus to Prague from Pilsen Bus to Prague from Pilsen
Bus Chisinau to Odesa Bus Chisinau to Odesa
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Bus to Odesa from Kyiv Bus to Odesa from Kyiv
Bus Bucharest - Odesa Bus Bucharest - Odesa
Popular Airport Shuttles to Prague and to Odesa
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