Bus Rochester, NY to Myrtle Beach, SC: Compare prices and save money

Compare all timetables for the bus from Rochester, NY to Myrtle Beach, SC

Here is a selection of the cheapest bus trips from the schedule from Rochester, NY to Myrtle Beach, SC from various bus operators like FlixBus or Greyhound US for the next days.

today

$160

tomorrow

$125

Wednesday

$121

Thursday

$113

Friday

$122

Saturday

Sunday

$112

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	42h 55m	10:15 PM	Rochester, NY	Greyhound	5:10 PM	Myrtle Beach, SC	Bus Stop		Economy	$160	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 1/19/2026 10:15:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/21/2026 5:10:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 42h 55m
	FlixBus	27h 45m	12:05 PM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$164	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/19/2026 12:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/20/2026 3:50:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 27h 45m

Did you know that if you travel from Rochester, NY to Myrtle Beach, SC via Washington, DC, you can save more than $17? You can find the corresponding connections below.
- FlixBus
  
  40h 15m
  
  0
  
  11:35 PM
  
  Rochester, NY
  Greyhound
  
  11:30 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $75
  
  A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/20/2026 11:35:00 PM to Union Station, Washington, DC (USA) arriving at 1/21/2026 11:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 11h 55m
- Busbud
  
  12h 10m
  
  0
  
  3:40 AM
  
  Washington, DC
  Union Station
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $68
  
  A Bus from Busbud goes from Union Station, Washington, DC (USA) at 1/22/2026 3:40:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/22/2026 3:50:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 12h 10m
Travel time is 12h 30m longer, but you will save $17

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	42h 55m	10:15 PM	Rochester, NY	Greyhound	5:10 PM	Myrtle Beach, SC	Bus Stop		Economy	$125	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 1/20/2026 10:15:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/22/2026 5:10:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 42h 55m
	FlixBus	27h 45m	12:05 PM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$129	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/20/2026 12:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/21/2026 3:50:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 27h 45m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	29h 30m	10:20 AM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$121	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/21/2026 10:20:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/22/2026 3:50:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 29h 30m
	Greyhound US	42h 55m	10:15 PM	Rochester, NY	Greyhound	5:10 PM	Myrtle Beach, SC	Bus Stop		Economy	$121	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 1/21/2026 10:15:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/23/2026 5:10:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 42h 55m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	40h 15m	11:35 PM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$113	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/22/2026 11:35:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/24/2026 3:50:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 40h 15m
	FlixBus	27h 45m	12:05 PM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$118	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/22/2026 12:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/23/2026 3:50:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 27h 45m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	27h 45m	12:05 PM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$122	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/23/2026 12:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/24/2026 3:50:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 27h 45m
	FlixBus	40h 15m	11:35 PM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$123	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/23/2026 11:35:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/25/2026 3:50:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 40h 15m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	27h 45m	12:05 PM	Rochester, NY	Greyhound	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$112	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 1/25/2026 12:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/26/2026 3:50:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 27h 45m
	Greyhound US	42h 55m	10:15 PM	Rochester, NY	Greyhound	5:10 PM	Myrtle Beach, SC	Bus Stop		Economy	$114	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 1/25/2026 10:15:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 1/27/2026 5:10:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 42h 55m

Best Price Offer: The price for the cheapest bus from Rochester, NY to Myrtle Beach, SC is $92 on 2/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Rochester, NY and Myrtle Beach, SC

See here how frequent the connections between Rochester, NY and Myrtle Beach, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 2 daily buses from Rochester, NY to Myrtle Beach, SC. Sunday has instead the fewest connections, with only 2 daily coaches between Rochester, NY and Myrtle Beach, SC.

The busiest time of the day is the Evening, with 6 buses from Rochester, NY to Myrtle Beach, SC, while Morning sees the fewest connections between Rochester, NY and Myrtle Beach, SC, with 1 offers.

Facts about the bus from Rochester, NY to Myrtle Beach, SC

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Rochester, NY to Myrtle Beach, SC in one click! Book your bus ticket from Rochester, NY to Myrtle Beach, SC starting from $92!

Cheapest Bus	$92
Fastest Bus	27h 45m
Earliest Bus	12:05 PM
Latest Bus	10:15 PM
Daily Bus Routes	2 Ø
Distance	657.9 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Rochester, NY to Myrtle Beach, SC

Every day, 2 buses from 2 bus companies leave Rochester, NY for Myrtle Beach, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$160

Tuesday 01/20

$125

Wednesday 01/21

$121

Thursday 01/22

$113

Friday 01/23

$122

Saturday 01/24

Sunday 01/25

$112

Monday 01/26

$104

Tuesday 01/27

$109

Wednesday 01/28

Thursday 01/29

$96

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

$92

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

$94

Friday 02/13

$97

Saturday 02/14

The cheapest time to travel from Rochester, NY to Myrtle Beach, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Rochester, NY to Myrtle Beach, SC, for the next 30 days.

With a price starting from $92, Sunday is the cheapest day for a bus from Rochester, NY to Myrtle Beach, SC. Wednesday instead is the most expensive day with prices starting from $121.

Afternoon is the cheapest day time for bus tickets from Rochester, NY to Myrtle Beach, SC, with $112. Morning is the most expensive time of the day with prices starting from $120.

How to save money travelling from Rochester, NY to Myrtle Beach, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rochester, NY to Myrtle Beach, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rochester, NY to Myrtle Beach, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rochester, NY to Myrtle Beach, SC are also emptier.

All bus stations and stops in Rochester, NY and Myrtle Beach, SC

In the map below, you can see where to find all bus stations in Rochester, NY and Myrtle Beach, SC.

Greyhound

Cumberland St 186

Rush Rhees Library

Library Rd 755

Trailways-LATS

Airport & Terminal Lower Leve

Raj Mahal Indian Restaurant

Jefferson Road 368

Bus Stop

7th Ave N 511

Service and Comfort on the bus from Rochester, NY to Myrtle Beach, SC

Want to know which seat classes are available on the buses from Rochester, NY to Myrtle Beach, SC? Or which bus companies serve the route Rochester, NY to Myrtle Beach, SC? Below you will find answers to your questions.

FAQs about the Rochester, NY to Myrtle Beach, SC bus

How much does a Rochester, NY Myrtle Beach, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $92 and takes 27h 45m to reach Myrtle Beach, SC. Compare offers to save money!

How much could I save by comparing buses from Rochester, NY to Myrtle Beach, SC?

This route is offered by 2 companies with a range of ticket prices between $92 and $164. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Myrtle Beach, SC.

On average, how many connections are available from Rochester, NY to Myrtle Beach, SC each day?

Every day, the Rochester, NY to Myrtle Beach, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rochester, NY to Myrtle Beach, SC take?

The fastest bus from Rochester, NY to Myrtle Beach, SC is offered by FlixBus and takes 27h 45m. Bus tickets for this connection cost $164. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rochester, NY to Myrtle Beach, SC?

The earliest bus arriving in Myrtle Beach, SC from Rochester, NY starts at 12:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rochester, NY to Myrtle Beach, SC?

The latest bus trip departing from Rochester, NY for Myrtle Beach, SC starts at 10:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rochester, NY Myrtle Beach, SC route?

When traveling by bus from Rochester, NY to Myrtle Beach, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rochester, NY and Myrtle Beach, SC?

You can check all the direct connections between Rochester, NY and Myrtle Beach, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Rochester, NY to Myrtle Beach, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rochester, NY Myrtle Beach, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rochester, NY Myrtle Beach, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rochester, NY to Myrtle Beach, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Rochester, NY to Myrtle Beach, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Rochester, NY and Myrtle Beach, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rochester, NY to Myrtle Beach, SC?

Prices and availability for 2 trips between Rochester, NY and Myrtle Beach, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rochester, NY to Myrtle Beach, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rochester, NY and to Myrtle Beach, SC

Here’s an overview of the most popular bus routes to Rochester, NY and to Myrtle Beach, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!