Bus Indianapolis to Myrtle Beach, SC

Compare all timetables for the bus from Indianapolis to Myrtle Beach, SC

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to Myrtle Beach, SC from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$97

Friday

$104

Saturday

$111

Sunday

$104

Monday

$97

Tuesday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	23h 45m	4:05 PM	Indianapolis	Central Bus Station	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$97	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 4/30/2026 4:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/1/2026 3:50:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 23h 45m
	FlixBus	21h 25m	6:25 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop		Economy	$97	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 4/30/2026 6:25:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/1/2026 3:50:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 21h 25m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 45m	4:05 PM	Indianapolis	Central Bus Station	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$104	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/1/2026 4:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/2/2026 3:50:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 45m
FlixBus	21h 25m	6:25 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$104	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/1/2026 6:25:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/2/2026 3:50:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 21h 25m
FlixBus	40h 20m	11:30 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$106	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/1/2026 11:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/3/2026 3:50:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 40h 20m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 45m	4:05 PM	Indianapolis	Central Bus Station	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$111	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/2/2026 4:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/3/2026 3:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 23h 45m
FlixBus	21h 25m	6:25 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$111	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/2/2026 6:25:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/3/2026 3:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 21h 25m
FlixBus	40h 20m	11:30 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$114	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/2/2026 11:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/4/2026 3:50:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 40h 20m

Did you know that if you travel from Indianapolis to Myrtle Beach, SC via Florence, SC, you can save more than $14? You can find the corresponding connections below.
- FlixBus
  
  21h 25m
  
  0
  
  6:25 PM
  
  Indianapolis
  Downtown Transit Center
  
  1:30 PM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $86
  
  A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 4/30/2026 6:25:00 PM to Bus Station, Florence, SC (USA) arriving at 5/1/2026 1:30:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 5m
- Greyhound US
  
  1h 40m
  
  0
  
  2:10 PM
  
  Florence, SC
  Bus Station
  
  3:50 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $11
  
  A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 5/1/2026 2:10:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/1/2026 3:50:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 1h 40m
Travel time is the same as the direct connection, but you will save $14

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 45m	4:05 PM	Indianapolis	Central Bus Station	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$104	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/3/2026 4:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/4/2026 3:50:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 45m
FlixBus	21h 25m	6:25 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$104	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/3/2026 6:25:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/4/2026 3:50:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 21h 25m
FlixBus	40h 20m	11:30 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$107	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/3/2026 11:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/5/2026 3:50:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 40h 20m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 45m	4:05 PM	Indianapolis	Central Bus Station	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$97	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/4/2026 4:05:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/5/2026 3:50:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 23h 45m
FlixBus	21h 25m	6:25 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$97	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/4/2026 6:25:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/5/2026 3:50:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 21h 25m
FlixBus	40h 20m	11:30 PM	Indianapolis	Washington / Delaware	3:50 PM	Myrtle Beach, SC	Bus Stop	Economy	$98	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/4/2026 11:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 5/6/2026 3:50:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 40h 20m

Best Price Offer: The price for the cheapest bus from Indianapolis to Myrtle Beach, SC is $97 on 4/30/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Indianapolis and Myrtle Beach, SC

See here how frequent the connections between Indianapolis and Myrtle Beach, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 3 daily buses from Indianapolis to Myrtle Beach, SC. Thursday has instead the fewest connections, with only 2 daily coaches between Indianapolis and Myrtle Beach, SC.

The busiest time of the day is the Evening, with 9 buses from Indianapolis to Myrtle Beach, SC, while Afternoon sees the fewest connections between Indianapolis and Myrtle Beach, SC, with 5 offers.

Facts about the bus from Indianapolis to Myrtle Beach, SC

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Indianapolis to Myrtle Beach, SC in one click! Book your bus ticket from Indianapolis to Myrtle Beach, SC starting from $97!

Cheapest Bus	$97
Fastest Bus	21h 25m
Earliest Bus	4:05 PM
Latest Bus	11:30 PM
Daily Bus Routes	2 Ø
Distance	581.4 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Indianapolis to Myrtle Beach, SC

Every day, 2 buses from 2 bus companies leave Indianapolis for Myrtle Beach, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/29/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

$97

Friday 05/01

$104

Saturday 05/02

$111

Sunday 05/03

$104

Monday 05/04

$97

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

$110

Sunday 05/10

$111

Monday 05/11

Tuesday 05/12

$101

Wednesday 05/13

Thursday 05/14

$97

Friday 05/15

Saturday 05/16

$111

Sunday 05/17

$104

Monday 05/18

$100

Tuesday 05/19

Wednesday 05/20

Thursday 05/21

Friday 05/22

Saturday 05/23

The cheapest time to travel from Indianapolis to Myrtle Beach, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Indianapolis to Myrtle Beach, SC, for the next 30 days.

With a price starting from $96, Thursday is the cheapest day for a bus from Indianapolis to Myrtle Beach, SC. Saturday instead is the most expensive day with prices starting from $110.

Afternoon is the cheapest day time for bus tickets from Indianapolis to Myrtle Beach, SC, with $97. Afternoon is the most expensive time of the day with prices starting from $97.

How to save money travelling from Indianapolis to Myrtle Beach, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to Myrtle Beach, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to Myrtle Beach, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to Myrtle Beach, SC are also emptier.

All bus stations and stops in Indianapolis and Myrtle Beach, SC

In the map below, you can see where to find all bus stations in Indianapolis and Myrtle Beach, SC.

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Bus Stop

7th Ave N 511

Service and Comfort on the bus from Indianapolis to Myrtle Beach, SC

Want to know which seat classes are available on the buses from Indianapolis to Myrtle Beach, SC? Or which bus companies serve the route Indianapolis to Myrtle Beach, SC? Below you will find answers to your questions.

FAQs about the Indianapolis to Myrtle Beach, SC bus

How much does a Indianapolis Myrtle Beach, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $97 and takes 23h 45m to reach Myrtle Beach, SC. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to Myrtle Beach, SC?

This route is offered by 2 companies with a range of ticket prices between $97 and $114. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Myrtle Beach, SC.

On average, how many connections are available from Indianapolis to Myrtle Beach, SC each day?

Every day, the Indianapolis to Myrtle Beach, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to Myrtle Beach, SC take?

The fastest bus from Indianapolis to Myrtle Beach, SC is offered by FlixBus and takes 21h 25m. Bus tickets for this connection cost $97. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to Myrtle Beach, SC?

The earliest bus arriving in Myrtle Beach, SC from Indianapolis starts at 4:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to Myrtle Beach, SC?

The latest bus trip departing from Indianapolis for Myrtle Beach, SC starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis Myrtle Beach, SC route?

When traveling by bus from Indianapolis to Myrtle Beach, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and Myrtle Beach, SC?

You can check all the direct connections between Indianapolis and Myrtle Beach, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Indianapolis to Myrtle Beach, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis Myrtle Beach, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis Myrtle Beach, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to Myrtle Beach, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to Myrtle Beach, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Indianapolis and Myrtle Beach, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to Myrtle Beach, SC?

Prices and availability for 2 trips between Indianapolis and Myrtle Beach, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to Myrtle Beach, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to Myrtle Beach, SC

Here’s an overview of the most popular bus routes to Indianapolis and to Myrtle Beach, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!