Bus San Francisco to Irvine, CA: Compare prices and save money

Compare all timetables for the bus from San Francisco to Irvine, CA

Here is a selection of the cheapest bus trips from the schedule from San Francisco to Irvine, CA from various bus operators like Greyhound US or FlixBus for the next days.

today

$78

tomorrow

$135

Saturday

Sunday

$126

Monday

Tuesday

Wednesday

$111

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	20h 5m	4:00 PM	San Francisco	Bus Station Transbay	12:05 PM	Irvine, CA	UC Irvine		Economy	$78	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/18/2025 4:00:00 PM to UC Irvine, Irvine, CA (USA) arriving at 12/19/2025 12:05:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 20h 5m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	20h 5m	4:00 PM	San Francisco	Bus Station Transbay	12:05 PM	Irvine, CA	UC Irvine		Economy	$135	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/19/2025 4:00:00 PM to UC Irvine, Irvine, CA (USA) arriving at 12/20/2025 12:05:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 20h 5m

Did you know that if you travel from San Francisco to Irvine, CA via Los Angeles, you can save more than $50? You can find the corresponding connections below.
- Busbud
  
  16h 49m
  
  0
  
  4:00 PM
  
  San Francisco
  Salesforce Transit Center
  
  7:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $46
  
  A Bus from Busbud goes from Salesforce Transit Center, San Francisco (USA) at 12/20/2025 4:00:00 PM to North Hollywood, Los Angeles (USA) arriving at 12/21/2025 7:10:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 15h 10m
- Distribusion
  
  1h 19m
  
  0
  
  7:30 AM
  
  Los Angeles
  Tufesa
  
  8:49 AM
  
  Irvine, CA
  Walnut-Wisteria Bus Stop
  
  0
  
  Basic
  
  $39
  
  A Bus from Distribusion goes from Tufesa, Los Angeles (USA) at 12/21/2025 7:30:00 AM to Walnut-Wisteria Bus Stop, Irvine, CA (USA) arriving at 12/21/2025 8:49:00 AM. 50 Basic ticket for $39 per person are available. Travel duration is 1h 19m
Travel Time is 3h 16m shorter, and you will save $50

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	20h 5m	4:00 PM	San Francisco	Bus Station Transbay	12:05 PM	Irvine, CA	UC Irvine		Economy	$126	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/21/2025 4:00:00 PM to UC Irvine, Irvine, CA (USA) arriving at 12/22/2025 12:05:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 20h 5m

Did you know that if you travel from San Francisco to Irvine, CA via Los Angeles, you can save more than $41? You can find the corresponding connections below.
- Busbud
  
  16h 49m
  
  0
  
  4:00 PM
  
  San Francisco
  Salesforce Transit Center
  
  7:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $46
  
  A Bus from Busbud goes from Salesforce Transit Center, San Francisco (USA) at 12/20/2025 4:00:00 PM to North Hollywood, Los Angeles (USA) arriving at 12/21/2025 7:10:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 15h 10m
- Distribusion
  
  1h 19m
  
  0
  
  7:30 AM
  
  Los Angeles
  Tufesa
  
  8:49 AM
  
  Irvine, CA
  Walnut-Wisteria Bus Stop
  
  0
  
  Basic
  
  $39
  
  A Bus from Distribusion goes from Tufesa, Los Angeles (USA) at 12/21/2025 7:30:00 AM to Walnut-Wisteria Bus Stop, Irvine, CA (USA) arriving at 12/21/2025 8:49:00 AM. 50 Basic ticket for $39 per person are available. Travel duration is 1h 19m
Travel Time is 3h 16m shorter, and you will save $41

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	17h 50m	6:15 PM	San Francisco	5th/Townsend	12:05 PM	Irvine, CA	UC Irvine		Economy	$111	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/24/2025 6:15:00 PM to UC Irvine, Irvine, CA (USA) arriving at 12/25/2025 12:05:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 17h 50m
	Greyhound US	14h 55m	9:10 PM	San Francisco	Bus Station Transbay	12:05 PM	Irvine, CA	UC Irvine		Economy	$113	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/24/2025 9:10:00 PM to UC Irvine, Irvine, CA (USA) arriving at 12/25/2025 12:05:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 14h 55m

Did you know that if you travel from San Francisco to Irvine, CA via Los Angeles, you can save more than $42? You can find the corresponding connections below.
- Busbud
  
  13h 25m
  
  0
  
  10:40 PM
  
  San Francisco
  Salesforce Transit Center
  
  7:55 AM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $53
  
  A Bus from Busbud goes from Salesforce Transit Center, San Francisco (USA) at 12/25/2025 10:40:00 PM to Union Station, Los Angeles (USA) arriving at 12/26/2025 7:55:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 9h 15m
- FlixBus
  
  1h 40m
  
  0
  
  10:25 AM
  
  Los Angeles
  University of Southern California (curbside)
  
  12:05 PM
  
  Irvine, CA
  UC Irvine
  
  0
  
  Economy
  
  $16
  
  A Bus from FlixBus goes from University of Southern California (curbside), Los Angeles (USA) at 12/26/2025 10:25:00 AM to UC Irvine, Irvine, CA (USA) arriving at 12/26/2025 12:05:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 1h 40m
Travel Time is 1h 30m shorter, and you will save $42

Best Price Offer: The price for the cheapest bus from San Francisco to Irvine, CA is $58 on 12/20/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between San Francisco and Irvine, CA

See here how frequent the connections between San Francisco and Irvine, CA are, during different times and days of the week.

Wednesday is the busiest day, with more than 2 daily buses from San Francisco to Irvine, CA. Sunday has instead the fewest connections, with only 1 daily coaches between San Francisco and Irvine, CA.

The busiest time of the day is the Afternoon, with 3 buses from San Francisco to Irvine, CA, while Evening sees the fewest connections between San Francisco and Irvine, CA, with 2 offers.

Facts about the bus from San Francisco to Irvine, CA

Compare all providers like Greyhound US and FlixBus that travel 1 times every day by bus from San Francisco to Irvine, CA in one click! Book your bus ticket from San Francisco to Irvine, CA starting from $58!

Cheapest Bus	$58
Fastest Bus	14h 55m
Earliest Bus	4:00 PM
Latest Bus	9:10 PM
Daily Bus Routes	1 Ø
Distance	381.6 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from San Francisco to Irvine, CA

Every day, 1 buses from 2 bus companies leave San Francisco for Irvine, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$78

Friday 12/19

$135

Saturday 12/20

$58

Sunday 12/21

$126

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$111

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from San Francisco to Irvine, CA

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to Irvine, CA, for the next 30 days.

With a price starting from $78, Thursday is the cheapest day for a bus from San Francisco to Irvine, CA. Friday instead is the most expensive day with prices starting from $134.

Afternoon is the cheapest day time for bus tickets from San Francisco to Irvine, CA, with $78. Evening is the most expensive time of the day with prices starting from $111.

How to save money travelling from San Francisco to Irvine, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to Irvine, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Irvine, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Irvine, CA are also emptier.

All bus stations and stops in San Francisco and Irvine, CA

In the map below, you can see where to find all bus stations in San Francisco and Irvine, CA.

5th/Townsend

Townsend St 400

Bus Station Transbay

Folsom Street 200

Beach St & Hyde St

Union Square

Post St 470

One Ferry Building

Passenger Loading Zone in front of Ferry Building on Embarcadero. Bus will stop near Marketbar Cafe.

UC Irvine

C Student Center

Shell Gas Station

Walnut-Wisteria Bus Stop

76 Gas Station

Culver-Scottsdale Bus Stop

Service and Comfort on the bus from San Francisco to Irvine, CA

Want to know which seat classes are available on the buses from San Francisco to Irvine, CA? Or which bus companies serve the route San Francisco to Irvine, CA? Below you will find answers to your questions.

FAQs about the San Francisco to Irvine, CA bus

How much does a San Francisco Irvine, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $58 and takes 20h 5m to reach Irvine, CA. Compare offers to save money!

How much could I save by comparing buses from San Francisco to Irvine, CA?

This route is offered by 2 companies with a range of ticket prices between $58 and $135. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Irvine, CA.

On average, how many connections are available from San Francisco to Irvine, CA each day?

Every day, the San Francisco to Irvine, CA bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to Irvine, CA take?

The fastest bus from San Francisco to Irvine, CA is offered by Greyhound US and takes 14h 55m. Bus tickets for this connection cost $113. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to Irvine, CA?

The earliest bus arriving in Irvine, CA from San Francisco starts at 4:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to Irvine, CA?

The latest bus trip departing from San Francisco for Irvine, CA starts at 9:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco Irvine, CA route?

When traveling by bus from San Francisco to Irvine, CA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and Irvine, CA?

You can check all the direct connections between San Francisco and Irvine, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to Irvine, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco Irvine, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco Irvine, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to Irvine, CA on your planned travel date.

How does CheckMyBus find the best bus deals from San Francisco to Irvine, CA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between San Francisco and Irvine, CA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Francisco to Irvine, CA?

Prices and availability for 1 trips between San Francisco and Irvine, CA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Francisco to Irvine, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to Irvine, CA

Here’s an overview of the most popular bus routes to San Francisco and to Irvine, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!