Compare all timetables for the bus from Santa Ana, CA to San Francisco
Cheapest bus trips tomorrow
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Greyhound US11h 10m07:30 PMSanta Ana, CABus Stop6:40 AMSan Francisco5th/Townsend0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 6/29/2025 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 6/30/2025 6:40:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 11h 10m
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Greyhound US9h 55m09:20 PMSanta Ana, CABus Stop7:15 AMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 6/29/2025 9:20:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 6/30/2025 7:15:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 9h 55m
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Greyhound US13h 50m09:15 AMSanta Ana, CABus Stop11:05 PMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 6/29/2025 9:15:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 6/29/2025 11:05:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 13h 50m
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Greyhound US10h 50m09:15 AMSanta Ana, CABus Stop8:05 PMSan Francisco5th/Townsend0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 6/29/2025 9:15:00 AM to 5th/Townsend, San Francisco (USA) arriving at 6/29/2025 8:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 10h 50m
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FlixBus14h 35m04:05 PMSanta Ana, CABus Stop5:10 PMLos AngelesUnion Station0EconomyA Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 6/30/2025 4:05:00 PM to Union Station, Los Angeles (USA) arriving at 6/30/2025 5:10:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 5m
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Busbud7h 25m011:15 PMLos AngelesUniversity of California (curbside)6:40 AMSan Francisco5th/Townsend0EconomyA Bus from Busbud goes from University of California (curbside), Los Angeles (USA) at 6/30/2025 11:15:00 PM to 5th/Townsend, San Francisco (USA) arriving at 7/1/2025 6:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 7h 25m
Waiting Time 6h 5m -
Cheapest bus trips Monday
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Greyhound US11h 10m07:30 PMSanta Ana, CABus Stop6:40 AMSan Francisco5th/Townsend0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 6/30/2025 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 7/1/2025 6:40:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 11h 10m
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Greyhound US13h 50m09:15 AMSanta Ana, CABus Stop11:05 PMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 6/30/2025 9:15:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 6/30/2025 11:05:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 50m
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Greyhound US9h 55m09:20 PMSanta Ana, CABus Stop7:15 AMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 6/30/2025 9:20:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 7/1/2025 7:15:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 9h 55m
Cheapest bus trips Wednesday
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Greyhound US11h 10m07:30 PMSanta Ana, CABus Stop6:40 AMSan Francisco5th/Townsend0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/2/2025 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 7/3/2025 6:40:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 11h 10m
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Greyhound US13h 50m09:15 AMSanta Ana, CABus Stop11:05 PMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/2/2025 9:15:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 7/2/2025 11:05:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 13h 50m
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Greyhound US9h 55m09:20 PMSanta Ana, CABus Stop7:15 AMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/2/2025 9:20:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 7/3/2025 7:15:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 9h 55m
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FlixBus14h 35m04:05 PMSanta Ana, CABus Stop5:10 PMLos AngelesUnion Station0EconomyA Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 6/30/2025 4:05:00 PM to Union Station, Los Angeles (USA) arriving at 6/30/2025 5:10:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 5m
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Busbud7h 25m011:15 PMLos AngelesUniversity of California (curbside)6:40 AMSan Francisco5th/Townsend0EconomyA Bus from Busbud goes from University of California (curbside), Los Angeles (USA) at 6/30/2025 11:15:00 PM to 5th/Townsend, San Francisco (USA) arriving at 7/1/2025 6:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 7h 25m
Waiting Time 6h 5m -
Cheapest bus trips Thursday
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Greyhound US10h 50m09:15 AMSanta Ana, CABus Stop8:05 PMSan Francisco5th/Townsend0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/3/2025 9:15:00 AM to 5th/Townsend, San Francisco (USA) arriving at 7/3/2025 8:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 10h 50m
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Greyhound US11h 10m07:30 PMSanta Ana, CABus Stop6:40 AMSan Francisco5th/Townsend0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/3/2025 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 7/4/2025 6:40:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 11h 10m
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Greyhound US13h 50m09:15 AMSanta Ana, CABus Stop11:05 PMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/3/2025 9:15:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 7/3/2025 11:05:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 50m
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Greyhound US9h 55m09:20 PMSanta Ana, CABus Stop7:15 AMSan FranciscoBus Station Transbay0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 7/3/2025 9:20:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 7/4/2025 7:15:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 9h 55m
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FlixBus14h 35m04:05 PMSanta Ana, CABus Stop5:10 PMLos AngelesUnion Station0EconomyA Bus from FlixBus goes from Bus Stop, Santa Ana, CA (USA) at 6/30/2025 4:05:00 PM to Union Station, Los Angeles (USA) arriving at 6/30/2025 5:10:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 5m
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Busbud7h 25m011:15 PMLos AngelesUniversity of California (curbside)6:40 AMSan Francisco5th/Townsend0EconomyA Bus from Busbud goes from University of California (curbside), Los Angeles (USA) at 6/30/2025 11:15:00 PM to 5th/Townsend, San Francisco (USA) arriving at 7/1/2025 6:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 7h 25m
Waiting Time 6h 5m -
Frequency of bus connections between Santa Ana, CA and San Francisco
Facts about the bus from Santa Ana, CA to San Francisco
Compare all providers like Greyhound US that travel 3 times every day by bus from Santa Ana, CA to San Francisco in one click! Book your bus ticket from Santa Ana, CA to San Francisco starting from $52!
Cheapest Bus | $52 |
Fastest Bus | 9h 55m |
Earliest Bus | 9:15 AM |
Latest Bus | 9:20 PM |
Daily Bus Routes | 3 Ø |
Distance | 376.9 miles |
Bus Companies | Greyhound US |
Cheapest bus connections from Santa Ana, CA to San Francisco
Every day, 3 buses from 1 bus companies leave Santa Ana, CA for San Francisco: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/28/2025 and for the following days.
The cheapest time to travel from Santa Ana, CA to San Francisco
How to save money travelling from Santa Ana, CA to San Francisco
Book the ticket from Santa Ana, CA to San Francisco in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Ana, CA to San Francisco, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Ana, CA to San Francisco are also emptier.All bus stations and stops in Santa Ana, CA and San Francisco
In the map below, you can see where to find all bus stations in Santa Ana, CA and San Francisco.
Service and Comfort on the bus from Santa Ana, CA to San Francisco
FAQs about the Santa Ana, CA to San Francisco bus
How much does a Santa Ana, CA San Francisco bus trip cost?
How much could I save by comparing buses from Santa Ana, CA to San Francisco?
On average, how many connections are available from Santa Ana, CA to San Francisco each day?
How long does a bus journey from Santa Ana, CA to San Francisco take?
What time is the first bus from Santa Ana, CA to San Francisco?
What time is the last bus from Santa Ana, CA to San Francisco?
Which bus companies operate the Santa Ana, CA San Francisco route?
Is there a direct bus between Santa Ana, CA and San Francisco?
What can I take with me on the Santa Ana, CA to San Francisco bus route?
What equipment is available for the Santa Ana, CA San Francisco bus route?
Available seat classes which are offered on the bus route Santa Ana, CA to San Francisco
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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