Compare all timetables for the bus from Santa Ana, CA to San Francisco
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 7:40 AM | Santa Ana, CA | Bus Stop | 8:45 PM | San Francisco | Salesforce Transit Center | Economy | $78 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/5/2026 7:40:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/5/2026 8:45:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 13h 5m
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| Greyhound US | 9h 45m | 9:25 PM | Santa Ana, CA | Bus Stop | 7:10 AM | San Francisco | Salesforce Transit Center | Economy | $81 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/5/2026 9:25:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 7:10:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 9h 45m
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| Greyhound US | 13h 0m | 7:30 PM | Santa Ana, CA | Bus Stop | 8:30 AM | San Francisco | 5th/Townsend | Economy | $86 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/5/2026 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 11/6/2026 8:30:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 13h 0m
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13h 55mSanta Ana, CA7 mi6:50 AMAnaheim, CAAnaheim Regional Transportation Intermodal Center8:45 PMSan FranciscoSalesforce Transit Center0 miEconomyA Bus from goes from Anaheim Regional Transportation Intermodal Center, Anaheim, CA (USA) at 11/5/2026 6:50:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/5/2026 8:45:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 13h 55m
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Greyhound US13h 5m07:40 AMSanta Ana, CABus Stop9:15 AMLos AngelesUnion Station0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:40:00 AM to Union Station, Los Angeles (USA) arriving at 11/6/2026 9:15:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
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Greyhound US9h 25m011:20 AMLos AngelesUnion Station8:45 PMSan FranciscoSalesforce Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 11/6/2026 11:20:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 8:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 25m
Waiting Time 2h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 7:40 AM | Santa Ana, CA | Bus Stop | 8:45 PM | San Francisco | Salesforce Transit Center | Economy | $83 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:40:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 8:45:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 13h 5m
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| Greyhound US | 9h 45m | 9:25 PM | Santa Ana, CA | Bus Stop | 7:10 AM | San Francisco | Salesforce Transit Center | Economy | $86 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 9:25:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 11/7/2026 7:10:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 9h 45m
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| Greyhound US | 13h 0m | 7:30 PM | Santa Ana, CA | Bus Stop | 8:30 AM | San Francisco | 5th/Townsend | Economy | $92 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 11/7/2026 8:30:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 0m
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Save more than 40%8h 15mSanta Ana, CA7 mi12:15 AMAnaheim, CAAnaheim Regional Transportation Intermodal Center8:30 AMSan Francisco5th/Townsend0 miEconomyA Bus from goes from Anaheim Regional Transportation Intermodal Center, Anaheim, CA (USA) at 11/6/2026 12:15:00 AM to 5th/Townsend, San Francisco (USA) arriving at 11/6/2026 8:30:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 8h 15m
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Greyhound US13h 5m07:40 AMSanta Ana, CABus Stop9:15 AMLos AngelesUnion Station0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:40:00 AM to Union Station, Los Angeles (USA) arriving at 11/6/2026 9:15:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
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Greyhound US9h 25m011:20 AMLos AngelesUnion Station8:45 PMSan FranciscoSalesforce Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 11/6/2026 11:20:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 8:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 25m
Waiting Time 2h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 7:40 AM | Santa Ana, CA | Bus Stop | 8:45 PM | San Francisco | Salesforce Transit Center | Economy | $71 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/7/2026 7:40:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/7/2026 8:45:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 13h 5m
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| Greyhound US | 13h 0m | 7:30 PM | Santa Ana, CA | Bus Stop | 8:30 AM | San Francisco | 5th/Townsend | Economy | $73 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/7/2026 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 11/8/2026 8:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 13h 0m
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| Greyhound US | 9h 45m | 9:25 PM | Santa Ana, CA | Bus Stop | 7:10 AM | San Francisco | Salesforce Transit Center | Economy | $94 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/7/2026 9:25:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 11/8/2026 7:10:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 9h 45m
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Save more than 34%8h 15mSanta Ana, CA7 mi12:15 AMAnaheim, CAAnaheim Regional Transportation Intermodal Center8:30 AMSan Francisco5th/Townsend0 miEconomyA Bus from goes from Anaheim Regional Transportation Intermodal Center, Anaheim, CA (USA) at 11/7/2026 12:15:00 AM to 5th/Townsend, San Francisco (USA) arriving at 11/7/2026 8:30:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 15m
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Greyhound US13h 5m07:40 AMSanta Ana, CABus Stop9:15 AMLos AngelesUnion Station0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:40:00 AM to Union Station, Los Angeles (USA) arriving at 11/6/2026 9:15:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
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Greyhound US9h 25m011:20 AMLos AngelesUnion Station8:45 PMSan FranciscoSalesforce Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 11/6/2026 11:20:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 8:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 25m
Waiting Time 2h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 14h 25m | 7:40 AM | Santa Ana, CA | Bus Stop | 10:05 PM | San Francisco | Salesforce Transit Center | Economy | $69 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/8/2026 7:40:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/8/2026 10:05:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 25m
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| Greyhound US | 9h 45m | 9:25 PM | Santa Ana, CA | Bus Stop | 7:10 AM | San Francisco | Salesforce Transit Center | Economy | $111 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/8/2026 9:25:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 11/9/2026 7:10:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 9h 45m
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| Greyhound US | 13h 5m | 7:40 AM | Santa Ana, CA | Bus Stop | 8:45 PM | San Francisco | Bus Station Transbay | Economy | $113 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/8/2026 7:40:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 11/8/2026 8:45:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 13h 5m
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| Greyhound US | 13h 0m | 7:30 PM | Santa Ana, CA | Bus Stop | 8:30 AM | San Francisco | 5th/Townsend | Economy | $133 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/8/2026 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 11/9/2026 8:30:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 13h 0m
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FlixBusSave more than 4%8h 15mSanta Ana, CA7 mi12:15 AMAnaheim, CAAnaheim Regional Transportation Intermodal Center8:30 AMSan Francisco5th/Townsend0 miEconomyA Bus from FlixBus goes from Anaheim Regional Transportation Intermodal Center, Anaheim, CA (USA) at 11/8/2026 12:15:00 AM to 5th/Townsend, San Francisco (USA) arriving at 11/8/2026 8:30:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 8h 15m
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Greyhound US13h 5m07:40 AMSanta Ana, CABus Stop9:15 AMLos AngelesUnion Station0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:40:00 AM to Union Station, Los Angeles (USA) arriving at 11/6/2026 9:15:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
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Greyhound US9h 25m011:20 AMLos AngelesUnion Station8:45 PMSan FranciscoSalesforce Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 11/6/2026 11:20:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 8:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 25m
Waiting Time 2h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 7:40 AM | Santa Ana, CA | Bus Stop | 8:45 PM | San Francisco | Salesforce Transit Center | Economy | $88 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/9/2026 7:40:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/9/2026 8:45:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 13h 5m
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| Greyhound US | 13h 0m | 7:30 PM | Santa Ana, CA | Bus Stop | 8:30 AM | San Francisco | 5th/Townsend | Economy | $90 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/9/2026 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 11/10/2026 8:30:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 13h 0m
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| Greyhound US | 9h 45m | 9:25 PM | Santa Ana, CA | Bus Stop | 7:10 AM | San Francisco | Salesforce Transit Center | Economy | $97 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/9/2026 9:25:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 11/10/2026 7:10:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 9h 45m
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Save more than 47%8h 15mSanta Ana, CA7 mi12:15 AMAnaheim, CAAnaheim Regional Transportation Intermodal Center8:30 AMSan Francisco5th/Townsend0 miEconomyA Bus from goes from Anaheim Regional Transportation Intermodal Center, Anaheim, CA (USA) at 11/9/2026 12:15:00 AM to 5th/Townsend, San Francisco (USA) arriving at 11/9/2026 8:30:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 15m
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Greyhound US13h 5m07:40 AMSanta Ana, CABus Stop9:15 AMLos AngelesUnion Station0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:40:00 AM to Union Station, Los Angeles (USA) arriving at 11/6/2026 9:15:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
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Greyhound US9h 25m011:20 AMLos AngelesUnion Station8:45 PMSan FranciscoSalesforce Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 11/6/2026 11:20:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 8:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 25m
Waiting Time 2h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 7:40 AM | Santa Ana, CA | Bus Stop | 8:45 PM | San Francisco | Salesforce Transit Center | Economy | $85 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/10/2026 7:40:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/10/2026 8:45:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 13h 5m
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| Greyhound US | 13h 0m | 7:30 PM | Santa Ana, CA | Bus Stop | 8:30 AM | San Francisco | 5th/Townsend | Economy | $86 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/10/2026 7:30:00 PM to 5th/Townsend, San Francisco (USA) arriving at 11/11/2026 8:30:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 13h 0m
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| Greyhound US | 9h 45m | 9:25 PM | Santa Ana, CA | Bus Stop | 7:10 AM | San Francisco | Bus Station Transbay | Economy | $98 |
A Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/10/2026 9:25:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 11/11/2026 7:10:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 9h 45m
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Save more than 47%8h 15mSanta Ana, CA7 mi12:15 AMAnaheim, CAAnaheim Regional Transportation Intermodal Center8:30 AMSan Francisco5th/Townsend0 miEconomyA Bus from goes from Anaheim Regional Transportation Intermodal Center, Anaheim, CA (USA) at 11/10/2026 12:15:00 AM to 5th/Townsend, San Francisco (USA) arriving at 11/10/2026 8:30:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 8h 15m
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Greyhound US13h 5m07:40 AMSanta Ana, CABus Stop9:15 AMLos AngelesUnion Station0EconomyA Bus from Greyhound US goes from Bus Stop, Santa Ana, CA (USA) at 11/6/2026 7:40:00 AM to Union Station, Los Angeles (USA) arriving at 11/6/2026 9:15:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 1h 35m
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Greyhound US9h 25m011:20 AMLos AngelesUnion Station8:45 PMSan FranciscoSalesforce Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 11/6/2026 11:20:00 AM to Salesforce Transit Center, San Francisco (USA) arriving at 11/6/2026 8:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 25m
Waiting Time 2h 5m -
Best Price Offer: The price for the cheapest bus from Santa Ana, CA to San Francisco is $67 on 11/4/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Santa Ana, CA and San Francisco
Facts about the bus from Santa Ana, CA to San Francisco
Compare all providers like Greyhound US that travel 5 times every day by bus from Santa Ana, CA to San Francisco in one click! Book your bus ticket from Santa Ana, CA to San Francisco starting from $67!
| Cheapest Bus | $67 |
| Fastest Bus | 9h 45m |
| Earliest Bus | 7:40 AM |
| Latest Bus | 9:25 PM |
| Daily Bus Routes | 5 Ø |
| Distance | 376.9 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Santa Ana, CA to San Francisco
Every day, 5 buses from 1 bus companies leave Santa Ana, CA for San Francisco: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/05/2026 and for the following days.
The cheapest time to travel from Santa Ana, CA to San Francisco
How to save money travelling from Santa Ana, CA to San Francisco
Book the ticket from Santa Ana, CA to San Francisco in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Ana, CA to San Francisco, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Ana, CA to San Francisco are also emptier.All bus stations and stops in Santa Ana, CA and San Francisco
In the map below, you can see where to find all bus stations in Santa Ana, CA and San Francisco.
Service and Comfort on the bus from Santa Ana, CA to San Francisco
FAQs about the Santa Ana, CA to San Francisco bus
How much does a Santa Ana, CA San Francisco bus trip cost?
How much could I save by comparing buses from Santa Ana, CA to San Francisco?
On average, how many connections are available from Santa Ana, CA to San Francisco each day?
How long does a bus journey from Santa Ana, CA to San Francisco take?
What time is the first bus from Santa Ana, CA to San Francisco?
What time is the last bus from Santa Ana, CA to San Francisco?
Which bus companies operate the Santa Ana, CA San Francisco route?
Is there a direct bus between Santa Ana, CA and San Francisco?
What can I take with me on the Santa Ana, CA to San Francisco bus route?
What equipment is available for the Santa Ana, CA San Francisco bus route?
How does CheckMyBus find the best bus deals from Santa Ana, CA to San Francisco?
How does CheckMyBus technology work for trips from Santa Ana, CA to San Francisco?
Available seat classes which are offered on the bus route Santa Ana, CA to San Francisco
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Santa Ana, CA and to San Francisco
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