Bus Springfield, MO to San Francisco: Compare prices and save money

Compare all timetables for the bus from Springfield, MO to San Francisco

Here is a selection of the cheapest bus trips from the schedule from Springfield, MO to San Francisco from various bus operators like Greyhound US for the next days.

today

tomorrow

Wednesday

Thursday

$206

Friday

$217

Saturday

Sunday

$209

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	62h 35m	6:40 PM	Springfield, MO	Bus Stop	7:15 AM	San Francisco	Salesforce Transit Center		Economy	$206	A Bus from Greyhound US goes from Bus Stop, Springfield, MO (USA) at 1/22/2026 6:40:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 1/25/2026 7:15:00 AM. 50 Economy ticket for $206 per person are available. Travel duration is 62h 35m
	Greyhound US	44h 20m	12:55 PM	Springfield, MO	Bus Stop	7:15 AM	San Francisco	Salesforce Transit Center		Economy	$256	A Bus from Greyhound US goes from Bus Stop, Springfield, MO (USA) at 1/22/2026 12:55:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 1/24/2026 7:15:00 AM. 50 Economy ticket for $256 per person are available. Travel duration is 44h 20m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	55h 10m	12:55 PM	Springfield, MO	W Chestnut Expy.	6:05 PM	San Francisco	5th/Townsend	Economy	$217	A Bus from Greyhound US goes from W Chestnut Expy., Springfield, MO (USA) at 1/23/2026 12:55:00 PM to 5th/Townsend, San Francisco (USA) arriving at 1/25/2026 6:05:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 55h 10m
Greyhound US	44h 20m	12:55 PM	Springfield, MO	W Chestnut Expy.	7:15 AM	San Francisco	Bus Station Transbay	Economy	$236	A Bus from Greyhound US goes from W Chestnut Expy., Springfield, MO (USA) at 1/23/2026 12:55:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 1/25/2026 7:15:00 AM. 50 Economy ticket for $236 per person are available. Travel duration is 44h 20m
Greyhound US	62h 35m	6:40 PM	Springfield, MO	W Chestnut Expy.	7:15 AM	San Francisco	Bus Station Transbay	Economy	$243	A Bus from Greyhound US goes from W Chestnut Expy., Springfield, MO (USA) at 1/23/2026 6:40:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 1/26/2026 7:15:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 62h 35m
Greyhound US	63h 25m	6:40 PM	Springfield, MO	W Chestnut Expy.	8:05 AM	San Francisco	5th/Townsend	Economy	$244	A Bus from Greyhound US goes from W Chestnut Expy., Springfield, MO (USA) at 1/23/2026 6:40:00 PM to 5th/Townsend, San Francisco (USA) arriving at 1/26/2026 8:05:00 AM. 50 Economy ticket for $244 per person are available. Travel duration is 63h 25m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	45h 10m	12:55 PM	Springfield, MO	Bus Stop	8:05 AM	San Francisco	5th/Townsend	Economy	$209	A Bus from Greyhound US goes from Bus Stop, Springfield, MO (USA) at 1/25/2026 12:55:00 PM to 5th/Townsend, San Francisco (USA) arriving at 1/27/2026 8:05:00 AM. 50 Economy ticket for $209 per person are available. Travel duration is 45h 10m
Greyhound US	44h 20m	12:55 PM	Springfield, MO	Bus Stop	7:15 AM	San Francisco	Salesforce Transit Center	Economy	$209	A Bus from Greyhound US goes from Bus Stop, Springfield, MO (USA) at 1/25/2026 12:55:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 1/27/2026 7:15:00 AM. 50 Economy ticket for $209 per person are available. Travel duration is 44h 20m
Greyhound US	62h 35m	6:40 PM	Springfield, MO	Bus Stop	7:15 AM	San Francisco	Salesforce Transit Center	Economy	$214	A Bus from Greyhound US goes from Bus Stop, Springfield, MO (USA) at 1/25/2026 6:40:00 PM to Salesforce Transit Center, San Francisco (USA) arriving at 1/28/2026 7:15:00 AM. 50 Economy ticket for $214 per person are available. Travel duration is 62h 35m
Greyhound US	63h 25m	6:40 PM	Springfield, MO	Bus Stop	8:05 AM	San Francisco	5th/Townsend	Economy	$215	A Bus from Greyhound US goes from Bus Stop, Springfield, MO (USA) at 1/25/2026 6:40:00 PM to 5th/Townsend, San Francisco (USA) arriving at 1/28/2026 8:05:00 AM. 50 Economy ticket for $215 per person are available. Travel duration is 63h 25m

Best Price Offer: The price for the cheapest bus from Springfield, MO to San Francisco is $165 on 2/3/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Springfield, MO and San Francisco

See here how frequent the connections between Springfield, MO and San Francisco are, during different times and days of the week.

Sunday is the busiest day, with more than 4 daily buses from Springfield, MO to San Francisco. Thursday has instead the fewest connections, with only 2 daily coaches between Springfield, MO and San Francisco.

The busiest time of the day is the Afternoon, with 5 buses from Springfield, MO to San Francisco, while Afternoon sees the fewest connections between Springfield, MO and San Francisco, with 5 offers.

Facts about the bus from Springfield, MO to San Francisco

Compare all providers like Greyhound US that travel 3 times every day by bus from Springfield, MO to San Francisco in one click! Book your bus ticket from Springfield, MO to San Francisco starting from $165!

Cheapest Bus	$165
Fastest Bus	42h 20m
Earliest Bus	12:55 PM
Latest Bus	6:40 PM
Daily Bus Routes	3 Ø
Distance	1,590.1 miles
Bus Companies	Greyhound US

Cheapest bus connections from Springfield, MO to San Francisco

Every day, 3 buses from 1 bus companies leave Springfield, MO for San Francisco: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

Tuesday 01/20

Wednesday 01/21

Thursday 01/22

$206

Friday 01/23

$217

Saturday 01/24

Sunday 01/25

$209

Monday 01/26

Tuesday 01/27

$260

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

$165

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Springfield, MO to San Francisco

See here on which day and which time of the day you can find the cheapest bus ticket from Springfield, MO to San Francisco, for the next 30 days.

With a price starting from $206, Thursday is the cheapest day for a bus from Springfield, MO to San Francisco. Friday instead is the most expensive day with prices starting from $217.

Evening is the cheapest day time for bus tickets from Springfield, MO to San Francisco, with $206. Afternoon is the most expensive time of the day with prices starting from $209.

How to save money travelling from Springfield, MO to San Francisco

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Springfield, MO to San Francisco in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Springfield, MO to San Francisco, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Springfield, MO to San Francisco are also emptier.

All bus stations and stops in Springfield, MO and San Francisco

In the map below, you can see where to find all bus stations in Springfield, MO and San Francisco.

Bus Stop

E Kearney St, 2425

W Chestnut Expy.

W Chestnut Expy. 4912

Greyhound Bus Station

2425 E Kearney St

5th/Townsend

Townsend St 400

Bus Station Transbay

Folsom Street 200

Beach St & Hyde St

One Ferry Building

Passenger Loading Zone in front of Ferry Building on Embarcadero. Bus will stop near Marketbar Cafe.

Stonestown

Buckingham Way 501

Service and Comfort on the bus from Springfield, MO to San Francisco

Want to know which seat classes are available on the buses from Springfield, MO to San Francisco? Or which bus companies serve the route Springfield, MO to San Francisco? Below you will find answers to your questions.

FAQs about the Springfield, MO to San Francisco bus

How much does a Springfield, MO San Francisco bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $165 and takes 60h 35m to reach San Francisco. Compare offers to save money!

How much could I save by comparing buses from Springfield, MO to San Francisco?

This route is offered by 1 companies with a range of ticket prices between $165 and $256. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Francisco.

On average, how many connections are available from Springfield, MO to San Francisco each day?

Every day, the Springfield, MO to San Francisco bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Springfield, MO to San Francisco take?

The fastest bus from Springfield, MO to San Francisco is offered by Greyhound US and takes 42h 20m. Bus tickets for this connection cost $256. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Springfield, MO to San Francisco?

The earliest bus arriving in San Francisco from Springfield, MO starts at 12:55 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Springfield, MO to San Francisco?

The latest bus trip departing from Springfield, MO for San Francisco starts at 6:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Springfield, MO San Francisco route?

When traveling by bus from Springfield, MO to San Francisco, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Springfield, MO and San Francisco?

You can check all the direct connections between Springfield, MO and San Francisco by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Springfield, MO to San Francisco bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Springfield, MO San Francisco bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Springfield, MO San Francisco bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Springfield, MO to San Francisco on your planned travel date.

How does CheckMyBus find the best bus deals from Springfield, MO to San Francisco?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Springfield, MO and San Francisco. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Springfield, MO to San Francisco?

Prices and availability for 3 trips between Springfield, MO and San Francisco change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Springfield, MO to San Francisco

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Springfield, MO and to San Francisco

Here’s an overview of the most popular bus routes to Springfield, MO and to San Francisco. Simply click on the connection of your choice, and you will find all the details about your bus route!