Bus Syracuse, NY to Charlotte: Compare prices and save money

Compare all timetables for the bus from Syracuse, NY to Charlotte

Here is a selection of the cheapest bus trips from the schedule from Syracuse, NY to Charlotte from various bus operators like FlixBus or Greyhound US for the next days.

today

$83

tomorrow

$78

Wednesday

$87

Thursday

$106

Friday

Saturday

$97

Sunday

$88

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	20h 25m	9:00 PM	Syracuse, NY	Regional Transit Center	5:25 PM	Charlotte	W Trade St	Economy	$83	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/22/2026 9:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/23/2026 5:25:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 20h 25m
FlixBus	19h 45m	10:45 AM	Syracuse, NY	Regional Transit Center	6:30 AM	Charlotte	W Trade St	Economy	$84	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/22/2026 10:45:00 AM to W Trade St, Charlotte (USA) arriving at 6/23/2026 6:30:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 19h 45m
FlixBus	22h 35m	6:15 PM	Syracuse, NY	Regional Transit Center	4:50 PM	Charlotte	W Trade St	Economy	$84	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/22/2026 6:15:00 PM to W Trade St, Charlotte (USA) arriving at 6/23/2026 4:50:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 22h 35m
Greyhound US	24h 0m	3:55 AM	Syracuse, NY	Regional Transit Center	3:55 AM	Charlotte	W Trade St	Economy	$84	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/22/2026 3:55:00 AM to W Trade St, Charlotte (USA) arriving at 6/23/2026 3:55:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 24h 0m
FlixBus	20h 25m	8:35 AM	Syracuse, NY	Regional Transit Center	5:00 AM	Charlotte	W Trade St	Economy	$85	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/22/2026 8:35:00 AM to W Trade St, Charlotte (USA) arriving at 6/23/2026 5:00:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 25m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 5m	10:45 AM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$78	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/23/2026 10:45:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/24/2026 6:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 20h 5m
Greyhound US	24h 20m	7:20 PM	Syracuse, NY	Regional Transit Center	7:40 PM	Charlotte	W Trade St	Economy	$78	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/23/2026 7:20:00 PM to W Trade St, Charlotte (USA) arriving at 6/24/2026 7:40:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 24h 20m
FlixBus	20h 25m	8:35 AM	Syracuse, NY	Regional Transit Center	5:00 AM	Charlotte	W Trade St	Economy	$79	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/23/2026 8:35:00 AM to W Trade St, Charlotte (USA) arriving at 6/24/2026 5:00:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 20h 25m
Greyhound US	27h 45m	9:00 PM	Syracuse, NY	Regional Transit Center	12:45 AM	Charlotte	W Trade St	Economy	$79	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/23/2026 9:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/25/2026 12:45:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 27h 45m
Greyhound US	33h 50m	9:00 PM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$79	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/23/2026 9:00:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 6/25/2026 6:50:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 33h 50m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 5m	10:45 AM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$87	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/24/2026 10:45:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/25/2026 6:50:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 20h 5m
FlixBus	21h 30m	3:15 AM	Syracuse, NY	Regional Transit Center	12:45 AM	Charlotte	W Trade St	Economy	$88	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/24/2026 3:15:00 AM to W Trade St, Charlotte (USA) arriving at 6/25/2026 12:45:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 21h 30m
FlixBus	19h 45m	10:45 AM	Syracuse, NY	Regional Transit Center	6:30 AM	Charlotte	W Trade St	Economy	$88	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/24/2026 10:45:00 AM to W Trade St, Charlotte (USA) arriving at 6/25/2026 6:30:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 45m
Greyhound US	24h 0m	3:55 AM	Syracuse, NY	Regional Transit Center	3:55 AM	Charlotte	W Trade St	Economy	$90	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/24/2026 3:55:00 AM to W Trade St, Charlotte (USA) arriving at 6/25/2026 3:55:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 24h 0m
Greyhound US	24h 20m	7:20 PM	Syracuse, NY	Regional Transit Center	7:40 PM	Charlotte	W Trade St	Economy	$93	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/24/2026 7:20:00 PM to W Trade St, Charlotte (USA) arriving at 6/25/2026 7:40:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 24h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 30m	3:15 AM	Syracuse, NY	Regional Transit Center	12:45 AM	Charlotte	W Trade St	Economy	$106	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/25/2026 3:15:00 AM to W Trade St, Charlotte (USA) arriving at 6/26/2026 12:45:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 21h 30m
FlixBus	20h 5m	10:45 AM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$106	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/25/2026 10:45:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/26/2026 6:50:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 20h 5m
Greyhound US	33h 50m	9:00 PM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$106	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/25/2026 9:00:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 6/27/2026 6:50:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 33h 50m
FlixBus	19h 45m	10:45 AM	Syracuse, NY	Regional Transit Center	6:30 AM	Charlotte	W Trade St	Economy	$107	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/25/2026 10:45:00 AM to W Trade St, Charlotte (USA) arriving at 6/26/2026 6:30:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 19h 45m
Greyhound US	24h 0m	3:55 AM	Syracuse, NY	Regional Transit Center	3:55 AM	Charlotte	W Trade St	Economy	$108	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/25/2026 3:55:00 AM to W Trade St, Charlotte (USA) arriving at 6/26/2026 3:55:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 30m	3:15 AM	Syracuse, NY	Regional Transit Center	12:45 AM	Charlotte	W Trade St	Economy	$97	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/27/2026 3:15:00 AM to W Trade St, Charlotte (USA) arriving at 6/28/2026 12:45:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 21h 30m
FlixBus	19h 45m	10:45 AM	Syracuse, NY	Regional Transit Center	6:30 AM	Charlotte	W Trade St	Economy	$97	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/27/2026 10:45:00 AM to W Trade St, Charlotte (USA) arriving at 6/28/2026 6:30:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 45m
FlixBus	20h 5m	10:45 AM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$97	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/27/2026 10:45:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/28/2026 6:50:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 20h 5m
Greyhound US	24h 0m	3:55 AM	Syracuse, NY	Regional Transit Center	3:55 AM	Charlotte	W Trade St	Economy	$98	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/27/2026 3:55:00 AM to W Trade St, Charlotte (USA) arriving at 6/28/2026 3:55:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 24h 0m
Greyhound US	33h 50m	9:00 PM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$98	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/27/2026 9:00:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 6/29/2026 6:50:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 33h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 25m	8:35 AM	Syracuse, NY	Regional Transit Center	5:00 AM	Charlotte	W Trade St	Economy	$88	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/28/2026 8:35:00 AM to W Trade St, Charlotte (USA) arriving at 6/29/2026 5:00:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 20h 25m
FlixBus	19h 45m	10:45 AM	Syracuse, NY	Regional Transit Center	6:30 AM	Charlotte	W Trade St	Economy	$89	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/28/2026 10:45:00 AM to W Trade St, Charlotte (USA) arriving at 6/29/2026 6:30:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 19h 45m
FlixBus	20h 5m	10:45 AM	Syracuse, NY	Regional Transit Center	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$89	A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 6/28/2026 10:45:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/29/2026 6:50:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 20h 5m
Greyhound US	24h 0m	3:55 AM	Syracuse, NY	Regional Transit Center	3:55 AM	Charlotte	W Trade St	Economy	$98	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/28/2026 3:55:00 AM to W Trade St, Charlotte (USA) arriving at 6/29/2026 3:55:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 24h 0m
Greyhound US	20h 25m	9:00 PM	Syracuse, NY	Regional Transit Center	5:25 PM	Charlotte	W Trade St	Economy	$104	A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 6/28/2026 9:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/29/2026 5:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 20h 25m

Best Price Offer: The price for the cheapest bus from Syracuse, NY to Charlotte is $78 on 6/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Syracuse, NY and Charlotte

See here how frequent the connections between Syracuse, NY and Charlotte are, during different times and days of the week.

Sunday is the busiest day, with more than 20 daily buses from Syracuse, NY to Charlotte. Monday has instead the fewest connections, with only 10 daily coaches between Syracuse, NY and Charlotte.

The busiest time of the day is the Evening, with 29 buses from Syracuse, NY to Charlotte, while Night sees the fewest connections between Syracuse, NY and Charlotte, with 20 offers.

Facts about the bus from Syracuse, NY to Charlotte

Compare all providers like FlixBus and Greyhound US that travel 16 times every day by bus from Syracuse, NY to Charlotte in one click! Book your bus ticket from Syracuse, NY to Charlotte starting from $78!

Cheapest Bus	$78
Fastest Bus	19h 5m
Earliest Bus	3:15 AM
Latest Bus	9:00 PM
Daily Bus Routes	16 Ø
Distance	599.2 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Syracuse, NY to Charlotte

Every day, 16 buses from 2 bus companies leave Syracuse, NY for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

$83

Tuesday 06/23

$78

Wednesday 06/24

$87

Thursday 06/25

$106

Friday 06/26

Saturday 06/27

$97

Sunday 06/28

$88

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

$108

Friday 07/10

$122

Saturday 07/11

$98

Sunday 07/12

$104

Monday 07/13

$100

Tuesday 07/14

$94

Wednesday 07/15

$107

Thursday 07/16

$110

Friday 07/17

$106

Saturday 07/18

The cheapest time to travel from Syracuse, NY to Charlotte

See here on which day and which time of the day you can find the cheapest bus ticket from Syracuse, NY to Charlotte, for the next 30 days.

With a price starting from $78, Tuesday is the cheapest day for a bus from Syracuse, NY to Charlotte. Thursday instead is the most expensive day with prices starting from $106.

Morning is the cheapest day time for bus tickets from Syracuse, NY to Charlotte, with $78. Afternoon is the most expensive time of the day with prices starting from $81.

How to save money travelling from Syracuse, NY to Charlotte

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Syracuse, NY to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Syracuse, NY to Charlotte, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Syracuse, NY to Charlotte are also emptier.

All bus stations and stops in Syracuse, NY and Charlotte

In the map below, you can see where to find all bus stations in Syracuse, NY and Charlotte.

University

University Pi 303

Regional Transit Center

Walsh Cir 1

S State St & E Genesee St

Destiny USA

Destiny USA Dr 9090

New York State Fairgrounds

State Fair Blvd 581

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Arrowood Light Rail Station

South Blvd 7430

Church St

S Church St 330

Service and Comfort on the bus from Syracuse, NY to Charlotte

Want to know which seat classes are available on the buses from Syracuse, NY to Charlotte? Or which bus companies serve the route Syracuse, NY to Charlotte? Below you will find answers to your questions.

FAQs about the Syracuse, NY to Charlotte bus

How much does a Syracuse, NY Charlotte bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $78 and takes 20h 5m to reach Charlotte. Compare offers to save money!

How much could I save by comparing buses from Syracuse, NY to Charlotte?

This route is offered by 2 companies with a range of ticket prices between $78 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.

On average, how many connections are available from Syracuse, NY to Charlotte each day?

Every day, the Syracuse, NY to Charlotte bus route is served by approximately 16 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Syracuse, NY to Charlotte take?

The fastest bus from Syracuse, NY to Charlotte is offered by FlixBus and takes 19h 5m. Bus tickets for this connection cost $85. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Syracuse, NY to Charlotte?

The earliest bus arriving in Charlotte from Syracuse, NY starts at 3:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Syracuse, NY to Charlotte?

The latest bus trip departing from Syracuse, NY for Charlotte starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Syracuse, NY Charlotte route?

When traveling by bus from Syracuse, NY to Charlotte, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Syracuse, NY and Charlotte?

You can check all the direct connections between Syracuse, NY and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Syracuse, NY to Charlotte bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Syracuse, NY Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Syracuse, NY Charlotte bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Syracuse, NY to Charlotte on your planned travel date.

How does CheckMyBus find the best bus deals from Syracuse, NY to Charlotte?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 16 daily trips between Syracuse, NY and Charlotte. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Syracuse, NY to Charlotte?

Prices and availability for 16 trips between Syracuse, NY and Charlotte change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Syracuse, NY to Charlotte

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Syracuse, NY and to Charlotte

Here’s an overview of the most popular bus routes to Syracuse, NY and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!