Bus Tampa to Port Saint Lucie, FL: Compare prices and save money

Compare all timetables for the bus from Tampa to Port Saint Lucie, FL

Here is a selection of the cheapest bus trips from the schedule from Tampa to Port Saint Lucie, FL from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$52

Saturday

Sunday

Monday

$38

Tuesday

Wednesday

$39

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 40m	10:35 PM	Tampa	Marion Street	3:15 AM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$52	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/5/2025 10:35:00 PM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/6/2025 3:15:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 4h 40m
Greyhound US	8h 50m	6:50 AM	Tampa	Marion Street	3:40 PM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$53	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/5/2025 6:50:00 AM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/5/2025 3:40:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 8h 50m
FlixBus	5h 25m	9:50 PM	Tampa	USF	3:15 AM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$66	A Bus from FlixBus goes from USF, Tampa (USA) at 12/5/2025 9:50:00 PM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/6/2025 3:15:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 5h 25m

Did you know that if you travel from Tampa to Port Saint Lucie, FL via Orlando, FL, you can save more than $14? You can find the corresponding connections below.
- Busbud
  
  5h 5m
  
  0
  
  4:10 PM
  
  Tampa
  USF
  
  6:00 PM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $11
  
  A Bus from Busbud goes from USF, Tampa (USA) at 12/6/2025 4:10:00 PM to Bus Station, Orlando, FL (USA) arriving at 12/6/2025 6:00:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 1h 50m
- Busbud
  
  2h 15m
  
  0
  
  7:00 PM
  
  Orlando, FL
  Jet Set Express Orlando Terminal
  
  9:15 PM
  
  Port Saint Lucie, FL
  Fort Pierce Service Plaza
  
  0
  
  Economy
  
  $27
  
  A Bus from Busbud goes from Jet Set Express Orlando Terminal, Orlando, FL (USA) at 12/6/2025 7:00:00 PM to Fort Pierce Service Plaza, Port Saint Lucie, FL (USA) arriving at 12/6/2025 9:15:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 2h 15m
Travel time is 0h 25m longer, but you will save $14

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 40m	10:35 PM	Tampa	Marion Street	3:15 AM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$38	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/8/2025 10:35:00 PM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/9/2025 3:15:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 4h 40m
Greyhound US	8h 50m	6:50 AM	Tampa	Marion Street	3:40 PM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$47	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/8/2025 6:50:00 AM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/8/2025 3:40:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 50m
FlixBus	5h 25m	9:50 PM	Tampa	USF	3:15 AM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$47	A Bus from FlixBus goes from USF, Tampa (USA) at 12/8/2025 9:50:00 PM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/9/2025 3:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 5h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 40m	10:35 PM	Tampa	Marion Street	3:15 AM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$39	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/10/2025 10:35:00 PM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/11/2025 3:15:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 4h 40m
Greyhound US	8h 50m	6:50 AM	Tampa	Marion Street	3:40 PM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$47	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/10/2025 6:50:00 AM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/10/2025 3:40:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 50m
FlixBus	5h 25m	9:50 PM	Tampa	USF	3:15 AM	Port Saint Lucie, FL	RaceTrac Gas Station	Economy	$47	A Bus from FlixBus goes from USF, Tampa (USA) at 12/10/2025 9:50:00 PM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/11/2025 3:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 5h 25m

Did you know that if you travel from Tampa to Port Saint Lucie, FL via Orlando, FL, you can save more than $4? You can find the corresponding connections below.
- Busbud
  
  4h 40m
  
  0
  
  10:35 PM
  
  Tampa
  Marion Street
  
  12:30 AM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $10
  
  A Bus from Busbud goes from Marion Street, Tampa (USA) at 12/8/2025 10:35:00 PM to Bus Station, Orlando, FL (USA) arriving at 12/9/2025 12:30:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 55m
- FlixBus
  
  2h 30m
  
  0
  
  12:45 AM
  
  Orlando, FL
  Bus Station
  
  3:15 AM
  
  Port Saint Lucie, FL
  RaceTrac Gas Station
  
  0
  
  Economy
  
  $24
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/9/2025 12:45:00 AM to RaceTrac Gas Station, Port Saint Lucie, FL (USA) arriving at 12/9/2025 3:15:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 2h 30m
Travel time is the same as the direct connection, but you will save $4

Best Price Offer: The price for the cheapest bus from Tampa to Port Saint Lucie, FL is $38 on 12/8/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Tampa and Port Saint Lucie, FL

See here how frequent the connections between Tampa and Port Saint Lucie, FL are, during different times and days of the week.

Monday is the busiest day, with more than 3 daily buses from Tampa to Port Saint Lucie, FL. Monday has instead the fewest connections, with only 3 daily coaches between Tampa and Port Saint Lucie, FL.

The busiest time of the day is the Evening, with 6 buses from Tampa to Port Saint Lucie, FL, while Morning sees the fewest connections between Tampa and Port Saint Lucie, FL, with 3 offers.

Facts about the bus from Tampa to Port Saint Lucie, FL

Compare all providers like FlixBus and Greyhound US that travel 3 times every day by bus from Tampa to Port Saint Lucie, FL in one click! Book your bus ticket from Tampa to Port Saint Lucie, FL starting from $38!

Cheapest Bus	$38
Fastest Bus	4h 40m
Earliest Bus	6:50 AM
Latest Bus	10:35 PM
Daily Bus Routes	3 Ø
Distance	137.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Tampa to Port Saint Lucie, FL

Every day, 3 buses from 2 bus companies leave Tampa for Port Saint Lucie, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$52

Saturday 12/06

Sunday 12/07

Monday 12/08

$38

Tuesday 12/09

Wednesday 12/10

$39

Thursday 12/11

$48

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Tampa to Port Saint Lucie, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Tampa to Port Saint Lucie, FL, for the next 30 days.

With a price starting from $38, Monday is the cheapest day for a bus from Tampa to Port Saint Lucie, FL. Friday instead is the most expensive day with prices starting from $52.

Evening is the cheapest day time for bus tickets from Tampa to Port Saint Lucie, FL, with $38. Morning is the most expensive time of the day with prices starting from $47.

How to save money travelling from Tampa to Port Saint Lucie, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to Port Saint Lucie, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to Port Saint Lucie, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to Port Saint Lucie, FL are also emptier.

All bus stations and stops in Tampa and Port Saint Lucie, FL

In the map below, you can see where to find all bus stations in Tampa and Port Saint Lucie, FL.

Marion Street

N Marion St 1211

USF

USF Holly Drive 3755

Greyhound Bus Station

East Polk Street 602

Western Union

Tampa Gateway Blvd, I 4 Exit 10 11706

Port of Tampa Cruise Terminals

Channelside Dr. 1101

Fort Pierce Service Plaza

Florida Turnpike Mile Marker 144

SW Gatlin Blvd & SW Brescia St Bus Stop

RaceTrac Gas Station

SW Gatlin Blvd 2031

Shell Gas Station

SW Saint Lucie West Blvd 1795

Service and Comfort on the bus from Tampa to Port Saint Lucie, FL

Want to know which seat classes are available on the buses from Tampa to Port Saint Lucie, FL? Or which bus companies serve the route Tampa to Port Saint Lucie, FL? Below you will find answers to your questions.

FAQs about the Tampa to Port Saint Lucie, FL bus

How much does a Tampa Port Saint Lucie, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $38 and takes 4h 40m to reach Port Saint Lucie, FL. Compare offers to save money!

How much could I save by comparing buses from Tampa to Port Saint Lucie, FL?

This route is offered by 2 companies with a range of ticket prices between $38 and $66. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Port Saint Lucie, FL.

On average, how many connections are available from Tampa to Port Saint Lucie, FL each day?

Every day, the Tampa to Port Saint Lucie, FL bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to Port Saint Lucie, FL take?

The fastest bus from Tampa to Port Saint Lucie, FL is offered by FlixBus and takes 4h 40m. Bus tickets for this connection cost $52. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to Port Saint Lucie, FL?

The earliest bus arriving in Port Saint Lucie, FL from Tampa starts at 6:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to Port Saint Lucie, FL?

The latest bus trip departing from Tampa for Port Saint Lucie, FL starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa Port Saint Lucie, FL route?

When traveling by bus from Tampa to Port Saint Lucie, FL, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and Port Saint Lucie, FL?

You can check all the direct connections between Tampa and Port Saint Lucie, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Tampa to Port Saint Lucie, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa Port Saint Lucie, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa Port Saint Lucie, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to Port Saint Lucie, FL on your planned travel date.

Available seat classes which are offered on the bus route Tampa to Port Saint Lucie, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to Port Saint Lucie, FL

Here’s an overview of the most popular bus routes to Tampa and to Port Saint Lucie, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!