Bus Tampa to San Francisco: Compare prices and save money

Compare all timetables for the bus from Tampa to San Francisco

Here is a selection of the cheapest bus trips from the schedule from Tampa to San Francisco from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$430

Monday

Tuesday

$375

Wednesday

Thursday

Friday

$340

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	71h 5m	11:10 AM	Tampa	Marion Street	7:15 AM	San Francisco	Bus Station Transbay	Economy	$430	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/21/2025 11:10:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 12/24/2025 7:15:00 AM. 50 Economy ticket for $430 per person are available. Travel duration is 71h 5m
FlixBus	75h 30m	6:20 AM	Tampa	Marion Street	6:50 AM	San Francisco	Bus Station Transbay	Economy	$431	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/21/2025 6:20:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 12/24/2025 6:50:00 AM. 50 Economy ticket for $431 per person are available. Travel duration is 75h 30m
FlixBus	80h 40m	5:25 PM	Tampa	Marion Street	11:05 PM	San Francisco	Bus Station Transbay	Economy	$453	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/21/2025 5:25:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 12/24/2025 11:05:00 PM. 50 Economy ticket for $453 per person are available. Travel duration is 80h 40m
FlixBus	80h 10m	5:55 PM	Tampa	USF	11:05 PM	San Francisco	Bus Station Transbay	Economy	$453	A Bus from FlixBus goes from USF, Tampa (USA) at 12/21/2025 5:55:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 12/24/2025 11:05:00 PM. 50 Economy ticket for $453 per person are available. Travel duration is 80h 10m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	80h 40m	5:25 PM	Tampa	Marion Street	11:05 PM	San Francisco	Bus Station Transbay	Economy	$375	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/23/2025 5:25:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 12/26/2025 11:05:00 PM. 50 Economy ticket for $375 per person are available. Travel duration is 80h 40m
FlixBus	80h 10m	5:55 PM	Tampa	USF	11:05 PM	San Francisco	Bus Station Transbay	Economy	$375	A Bus from FlixBus goes from USF, Tampa (USA) at 12/23/2025 5:55:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 12/26/2025 11:05:00 PM. 50 Economy ticket for $375 per person are available. Travel duration is 80h 10m
FlixBus	83h 15m	10:35 PM	Tampa	Marion Street	6:50 AM	San Francisco	Bus Station Transbay	Economy	$379	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/23/2025 10:35:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 12/27/2025 6:50:00 AM. 50 Economy ticket for $379 per person are available. Travel duration is 83h 15m
Greyhound US	71h 5m	11:10 AM	Tampa	Marion Street	7:15 AM	San Francisco	Bus Station Transbay	Economy	$398	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/23/2025 11:10:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 12/26/2025 7:15:00 AM. 50 Economy ticket for $398 per person are available. Travel duration is 71h 5m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	83h 15m	10:35 PM	Tampa	Marion Street	6:50 AM	San Francisco	Bus Station Transbay	Economy	$340	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/26/2025 10:35:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 12/30/2025 6:50:00 AM. 50 Economy ticket for $340 per person are available. Travel duration is 83h 15m
FlixBus	84h 0m	9:50 PM	Tampa	USF	6:50 AM	San Francisco	Bus Station Transbay	Economy	$340	A Bus from FlixBus goes from USF, Tampa (USA) at 12/26/2025 9:50:00 PM to Bus Station Transbay, San Francisco (USA) arriving at 12/30/2025 6:50:00 AM. 50 Economy ticket for $340 per person are available. Travel duration is 84h 0m
Greyhound US	71h 5m	11:10 AM	Tampa	Marion Street	7:15 AM	San Francisco	Bus Station Transbay	Economy	$398	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/26/2025 11:10:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 12/29/2025 7:15:00 AM. 50 Economy ticket for $398 per person are available. Travel duration is 71h 5m
FlixBus	75h 30m	6:20 AM	Tampa	Marion Street	6:50 AM	San Francisco	Bus Station Transbay	Economy	$404	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/26/2025 6:20:00 AM to Bus Station Transbay, San Francisco (USA) arriving at 12/29/2025 6:50:00 AM. 50 Economy ticket for $404 per person are available. Travel duration is 75h 30m

Best Price Offer: The price for the cheapest bus from Tampa to San Francisco is $281 on 12/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Tampa and San Francisco

See here how frequent the connections between Tampa and San Francisco are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Tampa to San Francisco. Tuesday has instead the fewest connections, with only 5 daily coaches between Tampa and San Francisco.

The busiest time of the day is the Afternoon, with 10 buses from Tampa to San Francisco, while Morning sees the fewest connections between Tampa and San Francisco, with 5 offers.

Facts about the bus from Tampa to San Francisco

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from Tampa to San Francisco in one click! Book your bus ticket from Tampa to San Francisco starting from $281!

Cheapest Bus	$281
Fastest Bus	68h 5m
Earliest Bus	6:20 AM
Latest Bus	10:35 PM
Daily Bus Routes	7 Ø
Distance	2,395.9 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Tampa to San Francisco

Every day, 7 buses from 2 bus companies leave Tampa for San Francisco: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/20/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

$430

Monday 12/22

Tuesday 12/23

$375

Wednesday 12/24

Thursday 12/25

Friday 12/26

$340

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Tampa to San Francisco

See here on which day and which time of the day you can find the cheapest bus ticket from Tampa to San Francisco, for the next 30 days.

With a price starting from $340, Friday is the cheapest day for a bus from Tampa to San Francisco. Sunday instead is the most expensive day with prices starting from $430.

Evening is the cheapest day time for bus tickets from Tampa to San Francisco, with $340. Morning is the most expensive time of the day with prices starting from $398.

How to save money travelling from Tampa to San Francisco

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to San Francisco in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to San Francisco, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to San Francisco are also emptier.

Beloved bus companies from Tampa to San Francisco

These are the most booked bus companies between Tampa to San Francisco from our users.

FlixBus from Tampa to San Francisco

Here you will find the key facts about the FlixBus bus route Tampa to San Francisco:

Cheapest Price	$340
Fastest Bus	72h 10m
Earliest Bus	6:20 AM
Last Bus	10:35 PM
Daily Connections	6 Ø
Found on	12/17/2025

Greyhound US from Tampa to San Francisco

Here you will find the key facts about the Greyhound US bus route Tampa to San Francisco:

Cheapest Price	$398
Fastest Bus	68h 5m
Earliest Bus	11:10 AM
Last Bus	11:10 AM
Daily Connections	1 Ø
Found on	12/17/2025

All bus stations and stops in Tampa and San Francisco

In the map below, you can see where to find all bus stations in Tampa and San Francisco.

Marion Street

N Marion St 1211

USF

USF Holly Drive 3755

Greyhound Bus Station

East Polk Street 602

Western Union

Tampa Gateway Blvd, I 4 Exit 10 11706

Port of Tampa Cruise Terminals

Channelside Dr. 1101

5th/Townsend

Townsend St 400

South Van Ness Ave & Market St

Beach St & Hyde St

Union Square

Post St 470

One Ferry Building

Passenger Loading Zone in front of Ferry Building on Embarcadero. Bus will stop near Marketbar Cafe.

Service and Comfort on the bus from Tampa to San Francisco

Want to know which seat classes are available on the buses from Tampa to San Francisco? Or which bus companies serve the route Tampa to San Francisco? Below you will find answers to your questions.

FAQs about the Tampa to San Francisco bus

How much does a Tampa San Francisco bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $281 and takes 80h 15m to reach San Francisco. Compare offers to save money!

How much could I save by comparing buses from Tampa to San Francisco?

This route is offered by 2 companies with a range of ticket prices between $281 and $535. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Francisco.

On average, how many connections are available from Tampa to San Francisco each day?

Every day, the Tampa to San Francisco bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to San Francisco take?

The fastest bus from Tampa to San Francisco is offered by Greyhound US and takes 68h 5m. Bus tickets for this connection cost $430. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to San Francisco?

The earliest bus arriving in San Francisco from Tampa starts at 6:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to San Francisco?

The latest bus trip departing from Tampa for San Francisco starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa San Francisco route?

When traveling by bus from Tampa to San Francisco, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and San Francisco?

You can check all the direct connections between Tampa and San Francisco by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Tampa to San Francisco bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa San Francisco bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa San Francisco bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to San Francisco on your planned travel date.

How does CheckMyBus find the best bus deals from Tampa to San Francisco?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Tampa and San Francisco. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tampa to San Francisco?

Prices and availability for 7 trips between Tampa and San Francisco change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tampa to San Francisco

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to San Francisco

Here’s an overview of the most popular bus routes to Tampa and to San Francisco. Simply click on the connection of your choice, and you will find all the details about your bus route!