What is the best way to travel from Cartagena to Santiago, RM?
Looking for a trip? Compare all the available Buses and Flights for the journey to Santiago, RM from Cartagena. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Santiago, RM from Cartagena?
You can get to Santiago, RM with just $255 by taking a Flight from LATAM Brasil, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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LATAM Brasil14h 57m012:20 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 12:20:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 14h 57m
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JetSmart16h 52m010:25 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 10:25:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 16h 52m
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LATAM Brasil12h 7m03:10 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 3:10:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $287 per person are available. Travel duration is 12h 7m
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JetSmart14h 11m01:06 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 1:06:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $293 per person are available. Travel duration is 14h 11m
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Avianca18h 42m08:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 8:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $305 per person are available. Travel duration is 18h 42m
Cheapest Flights Wednesday
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LATAM Brasil29h 32m09:45 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 9:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $300 per person are available. Travel duration is 29h 32m
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JetSmart29h 25m09:52 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 9:52:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $309 per person are available. Travel duration is 29h 25m
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JetSmart25h 4m010:07 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 10:07:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 12:11:00 AM. 50 Economy ticket for $323 per person are available. Travel duration is 25h 4m
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Avianca8h 40m04:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport2:15 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 4:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 2:15:00 PM. 50 Economy ticket for $357 per person are available. Travel duration is 8h 40m
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Avianca11h 50m010:30 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport11:20 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 10:30:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 11:20:00 PM. 50 Economy ticket for $357 per person are available. Travel duration is 11h 50m
Cheapest Flights Thursday
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JetSmart20h 32m06:45 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 6:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $288 per person are available. Travel duration is 20h 32m
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JetSMART Airlines Peru20h 32m06:45 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSMART Airlines Peru goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 6:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $298 per person are available. Travel duration is 20h 32m
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LATAM Brasil14h 57m012:20 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 12:20:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $344 per person are available. Travel duration is 14h 57m
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Avianca16h 21m06:50 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 6:50:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 12:11:00 AM. 50 Economy ticket for $351 per person are available. Travel duration is 16h 21m
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LAN Perú10h 50m05:00 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:50 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 5:00:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:50:00 AM. 50 Economy ticket for $353 per person are available. Travel duration is 10h 50m
Cheapest Flights Friday
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JetSmart31h 7m08:10 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 8:10:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 4:17:00 AM. 50 Economy ticket for $309 per person are available. Travel duration is 31h 7m
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Avianca29h 42m09:35 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 9:35:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 4:17:00 AM. 50 Economy ticket for $338 per person are available. Travel duration is 29h 42m
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JetSmart29h 51m09:01 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport3:52 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 9:01:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/3/2026 3:52:00 PM. 50 Economy ticket for $343 per person are available. Travel duration is 29h 51m
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LATAM Brasil20h 55m05:30 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport3:25 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 5:30:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/3/2026 3:25:00 AM. 50 Economy ticket for $358 per person are available. Travel duration is 20h 55m
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Avianca13h 8m08:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport10:43 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 8:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 10:43:00 PM. 50 Economy ticket for $374 per person are available. Travel duration is 13h 8m
Cheapest Flights Saturday
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Avianca24h 41m010:30 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 10:30:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $341 per person are available. Travel duration is 24h 41m
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JetSmart24h 4m011:07 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 11:07:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $351 per person are available. Travel duration is 24h 4m
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LAN Colombia14h 50m09:45 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport1:35 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Colombia goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 9:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 1:35:00 PM. 50 Economy ticket for $354 per person are available. Travel duration is 14h 50m
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LATAM Brasil14h 50m09:45 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport1:35 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 9:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 1:35:00 PM. 50 Economy ticket for $358 per person are available. Travel duration is 14h 50m
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JetSMART Airlines Peru19h 56m07:21 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSMART Airlines Peru goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 7:21:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 4:17:00 AM. 50 Economy ticket for $364 per person are available. Travel duration is 19h 56m
Cheapest Flights Sunday
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JetSmart15h 36m07:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 7:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $308 per person are available. Travel duration is 15h 36m
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JetSMART Airlines Peru15h 36m07:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSMART Airlines Peru goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 7:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $308 per person are available. Travel duration is 15h 36m
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Avianca16h 21m06:50 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 6:50:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $319 per person are available. Travel duration is 16h 21m
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LAN Perú16h 30m05:15 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport10:45 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 5:15:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 10:45:00 AM. 50 Economy ticket for $352 per person are available. Travel duration is 16h 30m
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LAN Colombia23h 30m04:55 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport5:25 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Colombia goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 4:55:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 5:25:00 PM. 50 Economy ticket for $355 per person are available. Travel duration is 23h 30m
Cheapest Flights Monday
What are the fastest trips from Cartagena to Santiago, RM?
You can get to Santiago, RM from Cartagena in just 8h 40m with a Flight from Avianca. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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LATAM Brasil12h 7m03:10 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 3:10:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $287 per person are available. Travel duration is 12h 7m
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JetSmart14h 11m01:06 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 1:06:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $293 per person are available. Travel duration is 14h 11m
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LATAM Brasil14h 57m012:20 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 12:20:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 14h 57m
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JetSmart16h 52m010:25 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 10:25:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 16h 52m
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Avianca18h 42m08:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/29/2026 8:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 4:17:00 AM. 50 Economy ticket for $305 per person are available. Travel duration is 18h 42m
Fastest Flights Wednesday
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Avianca8h 40m04:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport2:15 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 4:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 2:15:00 PM. 50 Economy ticket for $357 per person are available. Travel duration is 8h 40m
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Avianca11h 50m010:30 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport11:20 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 10:30:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/30/2026 11:20:00 PM. 50 Economy ticket for $357 per person are available. Travel duration is 11h 50m
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JetSmart25h 4m010:07 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 10:07:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 12:11:00 AM. 50 Economy ticket for $323 per person are available. Travel duration is 25h 4m
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JetSmart29h 25m09:52 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 9:52:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $309 per person are available. Travel duration is 29h 25m
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LATAM Brasil29h 32m09:45 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 4/30/2026 9:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $300 per person are available. Travel duration is 29h 32m
Fastest Flights Thursday
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LAN Perú10h 50m05:00 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:50 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 5:00:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:50:00 AM. 50 Economy ticket for $353 per person are available. Travel duration is 10h 50m
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LATAM Brasil14h 57m012:20 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 12:20:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $344 per person are available. Travel duration is 14h 57m
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Avianca16h 21m06:50 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 6:50:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 12:11:00 AM. 50 Economy ticket for $351 per person are available. Travel duration is 16h 21m
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JetSmart20h 32m06:45 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 6:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $288 per person are available. Travel duration is 20h 32m
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JetSMART Airlines Peru20h 32m06:45 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSMART Airlines Peru goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/1/2026 6:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 4:17:00 AM. 50 Economy ticket for $298 per person are available. Travel duration is 20h 32m
Fastest Flights Friday
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Avianca13h 8m08:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport10:43 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 8:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/2/2026 10:43:00 PM. 50 Economy ticket for $374 per person are available. Travel duration is 13h 8m
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LATAM Brasil20h 55m05:30 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport3:25 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 5:30:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/3/2026 3:25:00 AM. 50 Economy ticket for $358 per person are available. Travel duration is 20h 55m
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Avianca29h 42m09:35 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 9:35:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 4:17:00 AM. 50 Economy ticket for $338 per person are available. Travel duration is 29h 42m
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JetSmart29h 51m09:01 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport3:52 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 9:01:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/3/2026 3:52:00 PM. 50 Economy ticket for $343 per person are available. Travel duration is 29h 51m
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JetSmart31h 7m08:10 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/2/2026 8:10:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 4:17:00 AM. 50 Economy ticket for $309 per person are available. Travel duration is 31h 7m
Fastest Flights Saturday
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LAN Colombia14h 50m09:45 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport1:35 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Colombia goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 9:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 1:35:00 PM. 50 Economy ticket for $354 per person are available. Travel duration is 14h 50m
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LATAM Brasil14h 50m09:45 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport1:35 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LATAM Brasil goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 9:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 1:35:00 PM. 50 Economy ticket for $358 per person are available. Travel duration is 14h 50m
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JetSMART Airlines Peru19h 56m07:21 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport4:17 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSMART Airlines Peru goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 7:21:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/4/2026 4:17:00 AM. 50 Economy ticket for $364 per person are available. Travel duration is 19h 56m
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JetSmart24h 4m011:07 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 11:07:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $351 per person are available. Travel duration is 24h 4m
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Avianca24h 41m010:30 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/3/2026 10:30:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $341 per person are available. Travel duration is 24h 41m
Fastest Flights Sunday
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JetSmart15h 36m07:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 7:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $308 per person are available. Travel duration is 15h 36m
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JetSMART Airlines Peru15h 36m07:35 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSMART Airlines Peru goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 7:35:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $308 per person are available. Travel duration is 15h 36m
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Avianca16h 21m06:50 AMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport12:11 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Avianca goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 6:50:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 12:11:00 AM. 50 Economy ticket for $319 per person are available. Travel duration is 16h 21m
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LAN Perú16h 30m05:15 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport10:45 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 5:15:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 10:45:00 AM. 50 Economy ticket for $352 per person are available. Travel duration is 16h 30m
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LAN Colombia23h 30m04:55 PMRafael Núñez, Cartagena AirportRafael Núñez, Cartagena Airport5:25 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Colombia goes from Rafael Núñez, Cartagena Airport, Rafael Núñez, Cartagena Airport (Colombia) at 5/4/2026 4:55:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 5/5/2026 5:25:00 PM. 50 Economy ticket for $355 per person are available. Travel duration is 23h 30m
Fastest Flights Monday
Here you will find all operators and timetables for a
Bus from Cartagena to Santiago, RM
What are the most popular stations in Cartagena and Santiago, RM?
In Cartagena, you will usually depart from Bus Station, Hostal Pacho Lay or Muelle de la Bodeguita, while in Santiago, RM you will be arriving at Terminal Alameda, Terminal San Borja or Sur Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Santiago, RM from Cartagena? With 5 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Cartagena and Santiago, RM, you can pay as low as $255 with a Flight from LATAM Brasil.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Avianca: you will get to Santiago, RM in just 8h 40m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Cartagena and Santiago, RM are JetSmart, Avianca and LATAM Brasil, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Cartagena and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Rafael Núñez, Cartagena Airport or to Lo Prado, and look at flights from Rafael Núñez, Cartagena Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Cartagena to Santiago, RM?
The most popular companies between Cartagena and Santiago, RM, are JetSmart, Avianca and LATAM Brasil. Be sure to check their seat class offers and the amenities that they provide.
Airlines: JetSmart, Avianca, LATAM Brasil and 3 more.
All you need to know when you travel from Cartagena to Santiago, RM
Check all information on comfort and services on all modes of transports from Cartagena to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Cartagena to Santiago, RM
How can I reach Santiago, RM from Cartagena?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Santiago, RM from Cartagena.
How far is Santiago, RM from Cartagena?
The distance between Cartagena and Santiago, RM is 3,046.9 miles.
What is the most ecofriendly mode of transport between Cartagena and Santiago, RM?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 132 kgs of CO2, a train 172 kgs, a car 834 kgs, and a flight 1,206 kgs.
What is the cheapest mode of transport from Cartagena to Santiago, RM?
You can get to Santiago, RM with just $255 by taking a Flight from LATAM Brasil.
What is the fastest way to get from Cartagena to Santiago, RM?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 8h 40m with a Flight from Avianca.
More routes to Cartagena and to Santiago, RM
Looking for more options? Here you can see the most popular routes to Cartagena and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!
