What is the best way to travel from La Serena to Santiago, RM?
Looking for a trip? Compare all the available Buses and Flights for the journey to Santiago, RM from La Serena. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 13 available companies to find your perfect trip!
What is the cheapest way to reach Santiago, RM from La Serena?
You can get to Santiago, RM with just $7 by taking a Bus from Turbus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/18/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 7:00:00 AM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 6h 15m
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Cikbus Elité5h 40m05:20 PMLa SerenaBus Station11:00 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 4/18/2025 5:20:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 11:00:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 5h 40m
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Nueva Andimar Vip6h 10m04:50 PMLa SerenaBus Station11:00 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/18/2025 4:50:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 11:00:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 10m
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Pullman Bus6h 30m012:00 PMLa SerenaBus Stop6:30 PMSantiago, RMTerminal San Borja0First ClassA Bus from Pullman Bus goes from Bus Stop, La Serena (Chile) at 4/18/2025 12:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/18/2025 6:30:00 PM. 50 First Class ticket for $13 per person are available. Travel duration is 6h 30m
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Condor Bus6h 15m04:35 PMLa SerenaBus Station10:50 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/18/2025 4:35:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 10:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 15m
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Sky Airline1h 1m07:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport8:14 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 7:13:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 8:14:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m08:11 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:12 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 8:11:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 9:12:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 1h 1m
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LAN Perú0h 56m08:28 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:24 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 8:28:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 9:24:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m09:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:41 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 9:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 10:41:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m011:42 AMLa Florida, La Serena AirportLa Florida, La Serena Airport12:40 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 11:42:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 12:40:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 0h 58m
Cheapest Buses Friday
Cheapest Flights Friday
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/19/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/19/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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FlixBus6h 5m02:00 PMLa SerenaBus Station8:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/19/2025 2:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/19/2025 8:05:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 6h 5m
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Pluss Chile6h 40m012:05 AMLa SerenaBus Station6:45 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 4/19/2025 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/19/2025 6:45:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 40m
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Nueva Andimar Vip6h 10m012:50 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/19/2025 12:50:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/19/2025 7:00:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 10m
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Cikbus Elité7h 0m09:30 AMLa SerenaBus Stop4:30 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/19/2025 9:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/19/2025 4:30:00 PM. 50 Business ticket for $12 per person are available. Travel duration is 7h 0m
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LAN Perú0h 56m03:39 PMLa Florida, La Serena AirportLa Florida, La Serena Airport4:35 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 3:39:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 4:35:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m03:01 PMLa Florida, La Serena AirportLa Florida, La Serena Airport3:59 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 3:01:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 3:59:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 0h 58m
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LAN Perú0h 56m06:12 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:08 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 6:12:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 7:08:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 0h 56m
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Sky Airline1h 1m07:39 PMLa Florida, La Serena AirportLa Florida, La Serena Airport8:40 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 7:39:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 8:40:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m08:04 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:05 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 8:04:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 9:05:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 1h 1m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/20/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/20/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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Serena Mar6h 0m010:00 AMLa SerenaBus Station4:00 PMSantiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Bus Station, La Serena (Chile) at 4/20/2025 10:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/20/2025 4:00:00 PM. 50 First Class ticket for $12 per person are available. Travel duration is 6h 0m
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Nueva Andimar Vip6h 10m012:50 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/20/2025 12:50:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/20/2025 7:00:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 10m
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Pullman San Andres6h 15m06:45 PMLa SerenaBus Station1:00 AMSantiago, RMTerminal San Borja0Premium EconomyA Bus from Pullman San Andres goes from Bus Station, La Serena (Chile) at 4/20/2025 6:45:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/21/2025 1:00:00 AM. 50 Premium Economy ticket for $14 per person are available. Travel duration is 6h 15m
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Turbus6h 5m012:30 AMLa SerenaBus Stop6:35 AMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/20/2025 12:30:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/20/2025 6:35:00 AM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 5m
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LAN Perú0h 56m010:17 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:13 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 10:17:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 11:13:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m012:01 PMLa Florida, La Serena AirportLa Florida, La Serena Airport12:57 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 12:01:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 12:57:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 0h 56m
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Sky Airline1h 1m03:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport4:14 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 3:13:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 4:14:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 1h 1m
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JetSmart0h 58m01:03 PMLa Florida, La Serena AirportLa Florida, La Serena Airport2:01 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 1:03:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 2:01:00 PM. 50 Economy ticket for $205 per person are available. Travel duration is 0h 58m
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Sky Airline14h 41m07:02 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:43 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 7:02:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 9:43:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 14h 41m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Nueva Andimar Vip6h 10m04:50 PMLa SerenaBus Station11:00 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/21/2025 4:50:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2025 11:00:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 10m
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Pluss Chile6h 30m03:45 PMLa SerenaBus Station10:15 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 4/21/2025 3:45:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2025 10:15:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 30m
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Cikbus Elité5h 40m05:20 PMLa SerenaBus Stop11:00 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/21/2025 5:20:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/21/2025 11:00:00 PM. 50 Business ticket for $13 per person are available. Travel duration is 5h 40m
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Condor Bus6h 15m04:35 PMLa SerenaBus Station10:50 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/21/2025 4:35:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2025 10:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 15m
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Turbus6h 15m04:35 PMLa SerenaBus Station10:50 PMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Station, La Serena (Chile) at 4/21/2025 4:35:00 PM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/21/2025 10:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 15m
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JetSmart0h 58m05:10 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:08 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 5:10:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 6:08:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 0h 58m
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LAN Perú0h 56m08:45 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:41 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 8:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 9:41:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m07:00 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:56 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 7:00:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 7:56:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 0h 56m
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Sky Airline1h 1m06:05 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:06 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 6:05:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 7:06:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m012:14 PMLa Florida, La Serena AirportLa Florida, La Serena Airport1:15 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 12:14:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 1:15:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 1h 1m
Cheapest Buses Monday
Cheapest Flights Monday
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Turbus6h 5m06:55 AMLa SerenaBus Stop1:00 PMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/22/2025 6:55:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/22/2025 1:00:00 PM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 5m
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Condor Bus7h 10m09:45 PMLa SerenaBus Station4:55 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/22/2025 9:45:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/23/2025 4:55:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 7h 10m
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FlixBus6h 5m010:00 AMLa SerenaBus Station4:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/22/2025 10:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/22/2025 4:05:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 5m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/22/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/22/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m09:30 AMLa SerenaBus Stop4:30 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/22/2025 9:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/22/2025 4:30:00 PM. 50 Business ticket for $9 per person are available. Travel duration is 7h 0m
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JetSmart0h 58m011:12 AMLa Florida, La Serena AirportLa Florida, La Serena Airport12:10 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 11:12:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 12:10:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 0h 58m
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LAN Perú0h 56m09:46 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:42 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 9:46:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 10:42:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m010:57 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:53 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 10:57:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 11:53:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 0h 56m
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Sky Airline1h 1m03:28 PMLa Florida, La Serena AirportLa Florida, La Serena Airport4:29 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 3:28:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 4:29:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 1m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Condor Bus6h 30m03:15 AMLa SerenaBus Station9:45 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/23/2025 3:15:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/23/2025 9:45:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 30m
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Turbus6h 35m08:20 AMLa SerenaBus Stop2:55 PMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/23/2025 8:20:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/23/2025 2:55:00 PM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 35m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/23/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/23/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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FlixBus6h 5m011:00 AMLa SerenaBus Station5:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/23/2025 11:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/23/2025 5:05:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 5m
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Cikbus Elité7h 0m09:30 AMLa SerenaBus Stop4:30 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/23/2025 9:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/23/2025 4:30:00 PM. 50 Business ticket for $9 per person are available. Travel duration is 7h 0m
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JetSmart0h 58m010:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:43 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 10:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 11:43:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 0h 58m
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LAN Perú0h 56m09:03 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:59 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 9:03:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 9:59:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 0h 56m
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Sky Airline1h 1m09:06 PMLa Florida, La Serena AirportLa Florida, La Serena Airport10:07 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 9:06:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 10:07:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 1h 1m
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LAN Perú0h 56m09:50 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:46 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 9:50:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 10:46:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 0h 56m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Turbus6h 5m012:30 AMLa SerenaBus Stop6:35 AMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/24/2025 12:30:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/24/2025 6:35:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 5m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/24/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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FlixBus6h 5m010:00 AMLa SerenaBus Station4:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/24/2025 10:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/24/2025 4:05:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 5m
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Cikbus Elité7h 20m01:10 AMLa SerenaBus Station8:30 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 4/24/2025 1:10:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2025 8:30:00 AM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 7h 20m
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Pullman Bus6h 0m012:45 AMLa SerenaEl Sto, 10606:45 AMSantiago, RMTerminal San Borja0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 4/24/2025 12:45:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/24/2025 6:45:00 AM. 50 First Class ticket for $11 per person are available. Travel duration is 6h 0m
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Sky Airline1h 1m012:41 PMLa Florida, La Serena AirportLa Florida, La Serena Airport1:42 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 12:41:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 1:42:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 1m
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Air China Cargo1h 1m012:41 PMLa Florida, La Serena AirportLa Florida, La Serena Airport1:42 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Air China Cargo goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 12:41:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 1:42:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 1h 1m
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JetSmart0h 58m010:38 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:36 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 10:38:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 11:36:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 0h 58m
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LAN Perú0h 56m09:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:41 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 9:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 10:41:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 0h 56m
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Sky Airline1h 1m04:44 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:45 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 4:44:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 5:45:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 1h 1m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from La Serena to Santiago, RM?
You can get to Santiago, RM from La Serena in just 0h 56m with a Flight from LAN Perú. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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LAN Perú0h 56m08:28 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:24 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 8:28:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 9:24:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m09:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:41 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 9:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 10:41:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m011:42 AMLa Florida, La Serena AirportLa Florida, La Serena Airport12:40 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 11:42:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 12:40:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m07:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport8:14 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 7:13:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 8:14:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m08:11 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:12 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/18/2025 8:11:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/18/2025 9:12:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 1h 1m
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Cikbus Elité5h 40m05:20 PMLa SerenaBus Station11:00 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 4/18/2025 5:20:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 11:00:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 5h 40m
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Nueva Andimar Vip6h 10m04:50 PMLa SerenaBus Station11:00 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/18/2025 4:50:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 11:00:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/18/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 7:00:00 AM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 6h 15m
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Condor Bus6h 15m04:35 PMLa SerenaBus Station10:50 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/18/2025 4:35:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/18/2025 10:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 15m
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Pullman Bus6h 30m012:00 PMLa SerenaBus Stop6:30 PMSantiago, RMTerminal San Borja0First ClassA Bus from Pullman Bus goes from Bus Stop, La Serena (Chile) at 4/18/2025 12:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/18/2025 6:30:00 PM. 50 First Class ticket for $13 per person are available. Travel duration is 6h 30m
Fastest Flights Friday
Fastest Buses Friday
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LAN Perú0h 56m03:39 PMLa Florida, La Serena AirportLa Florida, La Serena Airport4:35 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 3:39:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 4:35:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m06:12 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:08 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 6:12:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 7:08:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m03:01 PMLa Florida, La Serena AirportLa Florida, La Serena Airport3:59 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 3:01:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 3:59:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m07:39 PMLa Florida, La Serena AirportLa Florida, La Serena Airport8:40 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 7:39:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 8:40:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m08:04 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:05 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/19/2025 8:04:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/19/2025 9:05:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 1h 1m
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FlixBus6h 5m02:00 PMLa SerenaBus Station8:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/19/2025 2:00:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/19/2025 8:05:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 6h 5m
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Nueva Andimar Vip6h 10m012:50 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/19/2025 12:50:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/19/2025 7:00:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/19/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/19/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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Pluss Chile6h 40m012:05 AMLa SerenaBus Station6:45 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 4/19/2025 12:05:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/19/2025 6:45:00 AM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 40m
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Cikbus Elité7h 0m09:30 AMLa SerenaBus Stop4:30 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/19/2025 9:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/19/2025 4:30:00 PM. 50 Business ticket for $12 per person are available. Travel duration is 7h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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LAN Perú0h 56m010:17 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:13 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 10:17:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 11:13:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m012:01 PMLa Florida, La Serena AirportLa Florida, La Serena Airport12:57 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 12:01:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 12:57:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m01:03 PMLa Florida, La Serena AirportLa Florida, La Serena Airport2:01 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 1:03:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 2:01:00 PM. 50 Economy ticket for $205 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m03:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport4:14 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 3:13:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/20/2025 4:14:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 1h 1m
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Sky Airline14h 41m07:02 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:43 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/20/2025 7:02:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 9:43:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 14h 41m
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Serena Mar6h 0m010:00 AMLa SerenaBus Station4:00 PMSantiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Bus Station, La Serena (Chile) at 4/20/2025 10:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/20/2025 4:00:00 PM. 50 First Class ticket for $12 per person are available. Travel duration is 6h 0m
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Turbus6h 5m012:30 AMLa SerenaBus Stop6:35 AMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/20/2025 12:30:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/20/2025 6:35:00 AM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 5m
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Nueva Andimar Vip6h 10m012:50 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/20/2025 12:50:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/20/2025 7:00:00 AM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/20/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/20/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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Pullman San Andres6h 15m06:45 PMLa SerenaBus Station1:00 AMSantiago, RMTerminal San Borja0Premium EconomyA Bus from Pullman San Andres goes from Bus Station, La Serena (Chile) at 4/20/2025 6:45:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/21/2025 1:00:00 AM. 50 Premium Economy ticket for $14 per person are available. Travel duration is 6h 15m
Fastest Flights Sunday
Fastest Buses Sunday
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LAN Perú0h 56m08:45 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:41 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 8:45:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 9:41:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m07:00 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:56 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 7:00:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 7:56:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m05:10 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:08 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 5:10:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 6:08:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m06:05 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:06 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 6:05:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 7:06:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m012:14 PMLa Florida, La Serena AirportLa Florida, La Serena Airport1:15 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/21/2025 12:14:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/21/2025 1:15:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 1h 1m
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Cikbus Elité5h 40m05:20 PMLa SerenaBus Stop11:00 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/21/2025 5:20:00 PM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/21/2025 11:00:00 PM. 50 Business ticket for $13 per person are available. Travel duration is 5h 40m
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Nueva Andimar Vip6h 10m04:50 PMLa SerenaBus Station11:00 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 4/21/2025 4:50:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2025 11:00:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 10m
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Condor Bus6h 15m04:35 PMLa SerenaBus Station10:50 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/21/2025 4:35:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2025 10:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 15m
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Turbus6h 15m04:35 PMLa SerenaBus Station10:50 PMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Station, La Serena (Chile) at 4/21/2025 4:35:00 PM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/21/2025 10:50:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 6h 15m
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Pluss Chile6h 30m03:45 PMLa SerenaBus Station10:15 PMSantiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 4/21/2025 3:45:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/21/2025 10:15:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 6h 30m
Fastest Flights Monday
Fastest Buses Monday
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LAN Perú0h 56m09:46 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:42 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 9:46:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 10:42:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m010:57 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:53 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 10:57:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 11:53:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m011:12 AMLa Florida, La Serena AirportLa Florida, La Serena Airport12:10 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 11:12:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 12:10:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m03:28 PMLa Florida, La Serena AirportLa Florida, La Serena Airport4:29 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/22/2025 3:28:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/22/2025 4:29:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 1m
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Turbus6h 5m06:55 AMLa SerenaBus Stop1:00 PMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/22/2025 6:55:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/22/2025 1:00:00 PM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 5m
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FlixBus6h 5m010:00 AMLa SerenaBus Station4:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/22/2025 10:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/22/2025 4:05:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 5m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/22/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/22/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m09:30 AMLa SerenaBus Stop4:30 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/22/2025 9:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/22/2025 4:30:00 PM. 50 Business ticket for $9 per person are available. Travel duration is 7h 0m
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Condor Bus7h 10m09:45 PMLa SerenaBus Station4:55 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/22/2025 9:45:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/23/2025 4:55:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 7h 10m
Fastest Flights Tuesday
Fastest Buses Tuesday
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LAN Perú0h 56m09:03 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:59 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 9:03:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 9:59:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m09:50 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:46 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 9:50:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 10:46:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m010:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:43 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 10:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 11:43:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m09:06 PMLa Florida, La Serena AirportLa Florida, La Serena Airport10:07 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/23/2025 9:06:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/23/2025 10:07:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 1h 1m
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FlixBus6h 5m011:00 AMLa SerenaBus Station5:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/23/2025 11:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/23/2025 5:05:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 5m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/23/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/23/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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Condor Bus6h 30m03:15 AMLa SerenaBus Station9:45 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 4/23/2025 3:15:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/23/2025 9:45:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 30m
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Turbus6h 35m08:20 AMLa SerenaBus Stop2:55 PMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/23/2025 8:20:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/23/2025 2:55:00 PM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 35m
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Cikbus Elité7h 0m09:30 AMLa SerenaBus Stop4:30 PMSantiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 4/23/2025 9:30:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/23/2025 4:30:00 PM. 50 Business ticket for $9 per person are available. Travel duration is 7h 0m
Fastest Flights Wednesday
Fastest Buses Wednesday
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LAN Perú0h 56m09:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport10:41 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 9:45:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 10:41:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m010:38 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:36 AMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 10:38:00 AM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 11:36:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m012:41 PMLa Florida, La Serena AirportLa Florida, La Serena Airport1:42 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 12:41:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 1:42:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 1m
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Air China Cargo1h 1m012:41 PMLa Florida, La Serena AirportLa Florida, La Serena Airport1:42 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Air China Cargo goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 12:41:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 1:42:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m04:44 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:45 PMSantiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 4/24/2025 4:44:00 PM to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 4/24/2025 5:45:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 1h 1m
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Pullman Bus6h 0m012:45 AMLa SerenaEl Sto, 10606:45 AMSantiago, RMTerminal San Borja0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 4/24/2025 12:45:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/24/2025 6:45:00 AM. 50 First Class ticket for $11 per person are available. Travel duration is 6h 0m
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Turbus6h 5m012:30 AMLa SerenaBus Stop6:35 AMSantiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Bus Stop, La Serena (Chile) at 4/24/2025 12:30:00 AM to Terminal Alameda, Santiago, RM (Chile) arriving at 4/24/2025 6:35:00 AM. 50 Premium Economy ticket for $7 per person are available. Travel duration is 6h 5m
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FlixBus6h 5m010:00 AMLa SerenaBus Station4:05 PMSantiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 4/24/2025 10:00:00 AM to Terminal San Borja, Santiago, RM (Chile) arriving at 4/24/2025 4:05:00 PM. 50 Economy ticket for $8 per person are available. Travel duration is 6h 5m
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Buses Romani6h 15m012:45 AMLa SerenaBus Station7:00 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 4/24/2025 12:45:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2025 7:00:00 AM. 50 Premium Economy ticket for $8 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 20m01:10 AMLa SerenaBus Station8:30 AMSantiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 4/24/2025 1:10:00 AM to Sur Bus Station, Santiago, RM (Chile) arriving at 4/24/2025 8:30:00 AM. 50 Premium Economy ticket for $10 per person are available. Travel duration is 7h 20m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from La Serena to Santiago, RM
What are the most popular stations in La Serena and Santiago, RM?
In La Serena, you will usually depart from Bus Stop, Bus Station or Corsario, while in Santiago, RM you will be arriving at Terminal San Borja, Los Libertadores Bus Stop or Terminal Pajaritos, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Santiago, RM from La Serena? With 9 connections between 13 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between La Serena and Santiago, RM, you can pay as low as $7 with a Bus from Turbus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Perú: you will get to Santiago, RM in just 0h 56m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting La Serena and Santiago, RM are LAN Perú, Sky Airline and JetSmart, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in La Serena and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Florida, La Serena Airport or to Lo Prado, and look at flights from La Florida, La Serena Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from La Serena to Santiago, RM?
The most popular companies between La Serena and Santiago, RM, are LAN Perú, Sky Airline and JetSmart. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Buses Romani, Cikbus Elité, Turbus and 7 more.
Airlines: LAN Perú, Sky Airline, JetSmart and 1 more.
All you need to know when you travel from La Serena to Santiago, RM
Check all information on comfort and services on all modes of transports from La Serena to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from La Serena to Santiago, RM
How can I reach Santiago, RM from La Serena?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Santiago, RM from La Serena.
How far is Santiago, RM from La Serena?
The distance between La Serena and Santiago, RM is 247.0 miles.
What is the most ecofriendly mode of transport between La Serena and Santiago, RM?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 68 kgs, and a flight 98 kgs.
What is the cheapest mode of transport from La Serena to Santiago, RM?
You can get to Santiago, RM with just $7 by taking a Bus from Turbus.
What is the fastest way to get from La Serena to Santiago, RM?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 0h 56m with a Flight from LAN Perú.
More routes to La Serena and to Santiago, RM
Looking for more options? Here you can see the most popular routes to La Serena and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!
- Trips to La Serena
- Antofagasta to La Serena
- Arica, AP to La Serena
- Concepción to La Serena
- Iquique to La Serena
- Mendoza to La Serena
- Puerto Montt to La Serena
- San Juan, SJ to La Serena
- Temuco to La Serena
- Trips to Santiago, RM
- Antofagasta to Santiago, RM
- Arica, AP to Santiago, RM
- Bariloche to Santiago, RM
- Buenos Aires to Santiago, RM
- Calama to Santiago, RM
- Copiapó to Santiago, RM
- Coquimbo to Santiago, RM
- Freire to Santiago, RM
- Iquique to Santiago, RM
- Los Ángeles, BI to Santiago, RM
- Mendoza to Santiago, RM
- Puerto Montt to Santiago, RM
- Rio de Janeiro to Santiago, RM
- Santiago de Chile Airport to Santiago, RM
- São Paulo to Santiago, RM
- Talcahuano to Santiago, RM
- Temuco to Santiago, RM
- Valdivia to Santiago, RM
- Viña del Mar to Santiago, RM