What is the best way to travel from Antofagasta to La Serena?
Looking for a trip? Compare all the available Flights and Buses for the journey to La Serena from Antofagasta. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 9 available companies to find your perfect trip!
What is the cheapest way to reach La Serena from Antofagasta?
You can get to La Serena with just $23 by taking a Flight from JetSmart, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/24/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/24/2026 10:50:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 45m
-
Cikbus Elité11h 15m03:10 AMAntofagastaCarlos Oviedo Cavada Bus Station2:25 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 3:10:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/24/2026 2:25:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 11h 15m
-
Pullman Bus12h 20m010:30 AMAntofagastaCamus Bus Station10:50 PMLa SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/24/2026 10:30:00 AM to El Sto, 1060, La Serena (Chile) arriving at 3/24/2026 10:50:00 PM. 50 First Class ticket for $33 per person are available. Travel duration is 12h 20m
-
JetSmart1h 25m06:57 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport8:22 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 6:57:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/24/2026 8:22:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 25m
-
LAN Perú22h 11m010:49 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:00 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 10:49:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/25/2026 9:00:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 22h 11m
-
LATAM Brasil22h 11m010:49 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:00 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 10:49:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/25/2026 9:00:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 22h 11m
-
LAN Airlines1h 25m05:59 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport7:24 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 5:59:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/24/2026 7:24:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 1h 25m
-
Sky Airline6h 54m08:38 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport3:32 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 8:38:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/24/2026 3:32:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 6h 54m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/25/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Nueva Andimar Vip12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 10:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 10:50:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 45m
-
FlixBus12h 10m03:35 AMAntofagastaCarlos Oviedo Cavada Bus Station3:45 PMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 3:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 3:45:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 12h 10m
Cheapest Buses Wednesday
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m06:30 PMAntofagastaCarlos Oviedo Cavada Bus Station6:40 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 6:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 6:40:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/26/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Nueva Andimar Vip12h 10m01:35 AMAntofagastaCarlos Oviedo Cavada Bus Station1:45 PMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 1:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 1:45:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 12h 10m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 10:50:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 45m
-
Sky Airline1h 25m012:42 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport2:07 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 12:42:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 2:07:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 25m02:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport4:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 2:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 4:13:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 1h 25m
-
JetSmart12h 30m08:30 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:00 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 8:30:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 9:00:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 12h 30m
-
LATAM Brasil1h 25m02:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport4:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 2:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 4:13:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 1h 25m
-
LAN Perú5h 40m08:44 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport2:24 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 8:44:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 2:24:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 5h 40m
Cheapest Buses Thursday
Cheapest Flights Thursday
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/27/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Nueva Andimar Vip12h 10m03:35 AMAntofagastaCarlos Oviedo Cavada Bus Station3:45 PMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 3:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 3:45:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 10:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 10:50:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 10h 45m
-
JetSmart1h 25m07:49 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:14 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 7:49:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 9:14:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 26m01:41 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport3:07 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 1:41:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 3:07:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 1h 26m
-
LATAM Brasil1h 26m01:41 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport3:07 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 1:41:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 3:07:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 1h 26m
-
Sky Airline1h 25m06:26 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport7:51 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 6:26:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 7:51:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 1h 25m
-
LAN Perú4h 2m05:38 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:40 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 5:38:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 9:40:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 4h 2m
Cheapest Buses Friday
Cheapest Flights Friday
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 10:50:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 10h 45m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m06:30 PMAntofagastaCarlos Oviedo Cavada Bus Station6:40 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 6:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 6:40:00 AM. 50 Economy ticket for $29 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 10:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 12h 10m
-
Pullman Bus12h 20m010:30 AMAntofagastaCamus Bus Station10:50 PMLa SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/28/2026 10:30:00 AM to El Sto, 1060, La Serena (Chile) arriving at 3/28/2026 10:50:00 PM. 50 First Class ticket for $33 per person are available. Travel duration is 12h 20m
Cheapest Buses Saturday
-
JetSmart1h 25m07:51 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:16 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 7:51:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 9:16:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 25m
-
LATAM Brasil1h 25m04:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport6:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 4:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 6:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 25m04:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport6:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 4:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 6:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 25m
-
Sky Airline7h 45m011:29 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport7:14 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 11:29:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 7:14:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 7h 45m
-
LAN Perú4h 13m011:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport4:00 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 11:47:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 4:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 4h 13m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/30/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/29/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/30/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Nueva Andimar Vip12h 10m01:35 AMAntofagastaCarlos Oviedo Cavada Bus Station1:45 PMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 1:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 1:45:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m01:35 AMAntofagastaCarlos Oviedo Cavada Bus Station1:45 PMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 1:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 1:45:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 12h 10m
-
Cikbus Elité11h 15m03:10 AMAntofagastaCarlos Oviedo Cavada Bus Station2:25 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 3:10:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 2:25:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 11h 15m
Cheapest Flights Sunday
Cheapest Buses Sunday
-
JetSmart1h 25m09:32 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:57 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 9:32:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 10:57:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 26m08:30 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:56 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 8:30:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 9:56:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 26m
-
LATAM Brasil1h 26m08:30 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:56 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 8:30:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 9:56:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 1h 26m
-
Sky Airline7h 26m09:43 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport5:09 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 9:43:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 5:09:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 7h 26m
-
LAN Perú18h 31m06:20 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:51 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 6:20:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/31/2026 12:51:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 31m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 10:10:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m06:30 PMAntofagastaCarlos Oviedo Cavada Bus Station6:40 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 6:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 6:40:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/30/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/30/2026 10:50:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 10h 45m
Cheapest Flights Monday
Cheapest Buses Monday
What are the fastest trips from Antofagasta to La Serena?
You can get to La Serena from Antofagasta in just 1h 25m with a Flight from JetSmart. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
JetSmart1h 25m06:57 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport8:22 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 6:57:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/24/2026 8:22:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 25m05:59 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport7:24 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 5:59:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/24/2026 7:24:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 1h 25m
-
Sky Airline6h 54m08:38 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport3:32 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 8:38:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/24/2026 3:32:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 6h 54m
-
LAN Perú22h 11m010:49 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:00 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 10:49:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/25/2026 9:00:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 22h 11m
-
LATAM Brasil22h 11m010:49 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:00 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/24/2026 10:49:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/25/2026 9:00:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 22h 11m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/24/2026 10:50:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 45m
-
Cikbus Elité11h 15m03:10 AMAntofagastaCarlos Oviedo Cavada Bus Station2:25 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 3:10:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/24/2026 2:25:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 11h 15m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/24/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/24/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Pullman Bus12h 20m010:30 AMAntofagastaCamus Bus Station10:50 PMLa SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/24/2026 10:30:00 AM to El Sto, 1060, La Serena (Chile) arriving at 3/24/2026 10:50:00 PM. 50 First Class ticket for $33 per person are available. Travel duration is 12h 20m
Fastest Flights Tuesday
Fastest Buses Tuesday
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 10:50:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 45m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/25/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 10:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m03:35 AMAntofagastaCarlos Oviedo Cavada Bus Station3:45 PMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/25/2026 3:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/25/2026 3:45:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 12h 10m
Fastest Buses Wednesday
-
Sky Airline1h 25m012:42 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport2:07 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 12:42:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 2:07:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 25m02:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport4:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 2:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 4:13:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 1h 25m
-
LATAM Brasil1h 25m02:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport4:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 2:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 4:13:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 1h 25m
-
LAN Perú5h 40m08:44 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport2:24 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 8:44:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/26/2026 2:24:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 5h 40m
-
JetSmart12h 30m08:30 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:00 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/26/2026 8:30:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 9:00:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 12h 30m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 10:50:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 10h 45m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/26/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m06:30 PMAntofagastaCarlos Oviedo Cavada Bus Station6:40 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 6:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 6:40:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m01:35 AMAntofagastaCarlos Oviedo Cavada Bus Station1:45 PMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/26/2026 1:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/26/2026 1:45:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 12h 10m
Fastest Flights Thursday
Fastest Buses Thursday
-
JetSmart1h 25m07:49 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:14 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 7:49:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 9:14:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 25m
-
Sky Airline1h 25m06:26 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport7:51 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 6:26:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 7:51:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 26m01:41 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport3:07 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 1:41:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 3:07:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 1h 26m
-
LATAM Brasil1h 26m01:41 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport3:07 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 1:41:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 3:07:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 1h 26m
-
LAN Perú4h 2m05:38 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:40 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/27/2026 5:38:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/27/2026 9:40:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 4h 2m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 10:50:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 10h 45m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/27/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m03:35 AMAntofagastaCarlos Oviedo Cavada Bus Station3:45 PMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 3:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/27/2026 3:45:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/27/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 10:10:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
Fastest Flights Friday
Fastest Buses Friday
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/28/2026 10:50:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 10h 45m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m06:30 PMAntofagastaCarlos Oviedo Cavada Bus Station6:40 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 6:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 6:40:00 AM. 50 Economy ticket for $29 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/28/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 10:10:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 12h 10m
-
Pullman Bus12h 20m010:30 AMAntofagastaCamus Bus Station10:50 PMLa SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/28/2026 10:30:00 AM to El Sto, 1060, La Serena (Chile) arriving at 3/28/2026 10:50:00 PM. 50 First Class ticket for $33 per person are available. Travel duration is 12h 20m
Fastest Buses Saturday
-
JetSmart1h 25m07:51 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:16 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 7:51:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 9:16:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 1h 25m
-
LATAM Brasil1h 25m04:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport6:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 4:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 6:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 25m04:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport6:13 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 4:48:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 6:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 25m
-
LAN Perú4h 13m011:47 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport4:00 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 11:47:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 4:00:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 4h 13m
-
Sky Airline7h 45m011:29 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport7:14 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/29/2026 11:29:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/29/2026 7:14:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 7h 45m
-
Cikbus Elité11h 15m03:10 AMAntofagastaCarlos Oviedo Cavada Bus Station2:25 PMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 3:10:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 2:25:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 11h 15m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/29/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/30/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/30/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m01:35 AMAntofagastaCarlos Oviedo Cavada Bus Station1:45 PMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 1:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 1:45:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m01:35 AMAntofagastaCarlos Oviedo Cavada Bus Station1:45 PMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/29/2026 1:35:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/29/2026 1:45:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 12h 10m
Fastest Flights Sunday
Fastest Buses Sunday
-
JetSmart1h 25m09:32 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:57 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 9:32:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 10:57:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 1h 25m
-
LAN Airlines1h 26m08:30 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:56 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 8:30:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 9:56:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 26m
-
LATAM Brasil1h 26m08:30 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport9:56 AMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 8:30:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 9:56:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 1h 26m
-
Sky Airline7h 26m09:43 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport5:09 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 9:43:00 AM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/30/2026 5:09:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 7h 26m
-
LAN Perú18h 31m06:20 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:51 PMLa Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 3/30/2026 6:20:00 PM to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 3/31/2026 12:51:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 31m
-
Pluss Chile10h 45m012:05 AMAntofagastaCarlos Oviedo Cavada Bus Station10:50 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 12:05:00 AM to Central Bus Station, La Serena (Chile) arriving at 3/30/2026 10:50:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 10h 45m
-
Cormar Bus11h 40m02:00 PMAntofagastaCamus Bus Station1:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Cormar Bus goes from Camus Bus Station, Antofagasta (Chile) at 3/30/2026 2:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 1:40:00 AM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m04:30 PMAntofagastaCarlos Oviedo Cavada Bus Station4:40 AMLa SerenaCentral Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 4:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 4:40:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 12h 10m
-
Nueva Andimar Vip12h 10m010:00 PMAntofagastaCarlos Oviedo Cavada Bus Station10:10 AMLa SerenaCentral Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 10:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 10:10:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 12h 10m
-
FlixBus12h 10m06:30 PMAntofagastaCarlos Oviedo Cavada Bus Station6:40 AMLa SerenaCentral Bus Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 3/30/2026 6:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 3/31/2026 6:40:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 12h 10m
Fastest Flights Monday
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Antofagasta to La Serena
What are the most popular stations in Antofagasta and La Serena?
In Antofagasta, you will usually depart from Maipú, Camus Bus Station or Carlos Oviedo Cavada Bus Station, while in La Serena you will be arriving at Avda. Fco de Aguirre Station, Central Bus Station or El Sto, 1060, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to La Serena from Antofagasta? With 8 connections between 9 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Antofagasta and La Serena, you can pay as low as $23 with a Flight from JetSmart.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from JetSmart: you will get to La Serena in just 1h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Antofagasta and La Serena are Pullman San Andres, Cormar Bus and Pluss Chile, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Antofagasta and La Serena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Negra or to La Florida, La Serena Airport, and look at flights from Andrés Sabella Gálvez, Antofagasta Airport, and landing at La Florida, La Serena Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Antofagasta to La Serena?
The most popular companies between Antofagasta and La Serena, are Pullman San Andres, Cormar Bus and Pluss Chile. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Pullman San Andres, Cormar Bus, Pluss Chile and 4 more.
Airlines: JetSmart, LAN Perú, LATAM Brasil and 2 more.
All you need to know when you travel from Antofagasta to La Serena
Check all information on comfort and services on all modes of transports from Antofagasta to La Serena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Antofagasta to La Serena
How can I reach La Serena from Antofagasta?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to La Serena from Antofagasta.
How far is La Serena from Antofagasta?
The distance between Antofagasta and La Serena is 435.4 miles.
What is the most ecofriendly mode of transport between Antofagasta and La Serena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 119 kgs, and a flight 172 kgs.
What is the cheapest mode of transport from Antofagasta to La Serena?
You can get to La Serena with just $23 by taking a Flight from JetSmart.
What is the fastest way to get from Antofagasta to La Serena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to La Serena in just 1h 25m with a Flight from JetSmart.
More routes to Antofagasta and to La Serena
Looking for more options? Here you can see the most popular routes to Antofagasta and to La Serena. Simply click on a connection, and you’ll find all the details about the route!
