What is the best way to travel from La Serena to Antofagasta?
Looking for a trip? Compare all the available Flights and Buses for the journey to Antofagasta from La Serena. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 9 available companies to find your perfect trip!
What is the cheapest way to reach Antofagasta from La Serena?
You can get to Antofagasta with just $6 by taking a Bus from Nueva Andimar Vip, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
Cikbus Elité11h 40m08:55 PMLa SerenaCentral Bus Station8:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/22/2026 8:55:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 8:35:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 40m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/22/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/23/2026 6:40:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 40m
-
Pluss Chile11h 20m02:20 PMLa SerenaCentral Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/22/2026 2:20:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 1:40:00 AM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 20m
-
Pullman San Andres12h 10m010:00 PMLa SerenaCentral Bus Station10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/22/2026 10:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 10:10:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
-
FlixBus11h 35m04:00 PMLa SerenaCentral Bus Station3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/22/2026 4:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 3:35:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 35m
-
JetSmart1h 20m010:06 PMLa Florida, La Serena AirportLa Florida, La Serena Airport11:26 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 10:06:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 11:26:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 20m
-
Sky Airline1h 25m03:41 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:06 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 3:41:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 5:06:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 1h 25m
-
LAN Perú4h 49m09:40 AMLa Florida, La Serena AirportLa Florida, La Serena Airport2:29 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 9:40:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 2:29:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 4h 49m
-
LAN Airlines1h 16m08:32 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 8:32:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 9:48:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 1h 16m
-
LATAM Brasil1h 16m08:40 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:56 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 8:40:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 9:56:00 PM. 50 Economy ticket for $240 per person are available. Travel duration is 1h 16m
Cheapest Buses Sunday
Cheapest Flights Sunday
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/23/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/23/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/23/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/24/2026 6:40:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/23/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
-
FlixBus11h 35m04:00 PMLa SerenaCentral Bus Station3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/23/2026 4:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 3:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 35m
-
JetSmart1h 20m011:30 AMLa Florida, La Serena AirportLa Florida, La Serena Airport12:50 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 11:30:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 12:50:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 1h 20m
-
Sky Airline19h 10m012:21 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 12:21:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:31:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 19h 10m
-
LAN Perú21h 51m09:40 AMLa Florida, La Serena AirportLa Florida, La Serena Airport7:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 9:40:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:31:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 21h 51m
-
LAN Airlines1h 19m010:26 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:45 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 10:26:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 11:45:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 1h 19m
-
LATAM Brasil1h 19m010:26 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:45 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 10:26:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 11:45:00 AM. 50 Economy ticket for $190 per person are available. Travel duration is 1h 19m
Cheapest Buses Monday
Cheapest Flights Monday
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/24/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/24/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
FlixBus11h 35m05:10 PMLa SerenaCentral Bus Station4:45 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/24/2026 5:10:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 4:45:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/24/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/24/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/25/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 40m
-
JetSmart1h 20m09:00 PMLa Florida, La Serena AirportLa Florida, La Serena Airport10:20 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 9:00:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 10:20:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 1h 20m
-
LAN Airlines1h 16m08:09 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:25 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 8:09:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 9:25:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 1h 16m
-
LATAM Brasil1h 16m08:09 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:25 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 8:09:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 9:25:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 1h 16m
-
Sky Airline21h 32m010:28 AMLa Florida, La Serena AirportLa Florida, La Serena Airport8:00 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 10:28:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/25/2026 8:00:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 21h 32m
-
LAN Perú20h 45m09:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport6:30 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 9:45:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/25/2026 6:30:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 20h 45m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/25/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/25/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/25/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/25/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 1:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 11h 35m
-
Cormar Bus11h 40m05:35 AMLa SerenaCentral Bus Station5:15 PMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/25/2026 5:35:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 3/25/2026 5:15:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 11h 40m
Cheapest Buses Wednesday
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/26/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/26/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/26/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/26/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/26/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
-
JetSmart1h 20m06:37 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:57 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 6:37:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 7:57:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 20m
-
LAN Airlines1h 16m04:59 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:15 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 4:59:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:15:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 1h 16m
-
LATAM Brasil1h 16m04:59 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:15 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 4:59:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:15:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 16m
-
Sky Airline6h 23m02:55 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:18 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 2:55:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 9:18:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 6h 23m
-
LAN Perú18h 27m012:04 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 12:04:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 6:31:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 27m
Cheapest Buses Thursday
Cheapest Flights Thursday
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/27/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/27/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/27/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 6:40:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 40m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/27/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 1:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 11h 35m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/27/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 1:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 11h 35m
-
JetSmart1h 20m09:59 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:19 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 9:59:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 11:19:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 1h 20m
-
LATAM Brasil1h 16m03:57 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:13 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 3:57:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 16m
-
LAN Airlines1h 16m03:57 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:13 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 3:57:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 16m
-
Sky Airline8h 6m09:40 AMLa Florida, La Serena AirportLa Florida, La Serena Airport5:46 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 9:40:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:46:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 8h 6m
-
LAN Perú15h 58m05:01 PMLa Florida, La Serena AirportLa Florida, La Serena Airport8:59 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 5:01:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/28/2026 8:59:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 15h 58m
Cheapest Buses Friday
Cheapest Flights Friday
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/28/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 11h 35m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/28/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/28/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/28/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/29/2026 6:40:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 11h 40m
-
Pullman Bus13h 5m03:30 AMLa SerenaEl Sto, 10604:35 PMAntofagastaCamus Bus Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 3/28/2026 3:30:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 4:35:00 PM. 50 First Class ticket for $45 per person are available. Travel duration is 13h 5m
Cheapest Buses Saturday
What are the fastest trips from La Serena to Antofagasta?
You can get to Antofagasta from La Serena in just 1h 16m with a Flight from LAN Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
LAN Airlines1h 16m08:32 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:48 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 8:32:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 9:48:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 1h 16m
-
LATAM Brasil1h 16m08:40 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:56 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 8:40:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 9:56:00 PM. 50 Economy ticket for $240 per person are available. Travel duration is 1h 16m
-
JetSmart1h 20m010:06 PMLa Florida, La Serena AirportLa Florida, La Serena Airport11:26 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 10:06:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 11:26:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 1h 20m
-
Sky Airline1h 25m03:41 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:06 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 3:41:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 5:06:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 1h 25m
-
LAN Perú4h 49m09:40 AMLa Florida, La Serena AirportLa Florida, La Serena Airport2:29 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/22/2026 9:40:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/22/2026 2:29:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 4h 49m
-
Pluss Chile11h 20m02:20 PMLa SerenaCentral Bus Station1:40 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/22/2026 2:20:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 1:40:00 AM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 20m
-
FlixBus11h 35m04:00 PMLa SerenaCentral Bus Station3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/22/2026 4:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 3:35:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 35m
-
Cikbus Elité11h 40m08:55 PMLa SerenaCentral Bus Station8:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/22/2026 8:55:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 8:35:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 40m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/22/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/23/2026 6:40:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m010:00 PMLa SerenaCentral Bus Station10:10 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/22/2026 10:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 10:10:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
Fastest Flights Sunday
Fastest Buses Sunday
-
LAN Airlines1h 19m010:26 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:45 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 10:26:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 11:45:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 1h 19m
-
LATAM Brasil1h 19m010:26 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:45 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 10:26:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 11:45:00 AM. 50 Economy ticket for $190 per person are available. Travel duration is 1h 19m
-
JetSmart1h 20m011:30 AMLa Florida, La Serena AirportLa Florida, La Serena Airport12:50 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 11:30:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/23/2026 12:50:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 1h 20m
-
Sky Airline19h 10m012:21 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 12:21:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:31:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 19h 10m
-
LAN Perú21h 51m09:40 AMLa Florida, La Serena AirportLa Florida, La Serena Airport7:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/23/2026 9:40:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 7:31:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 21h 51m
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/23/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
FlixBus11h 35m04:00 PMLa SerenaCentral Bus Station3:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/23/2026 4:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 3:35:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 35m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/23/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/24/2026 6:40:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 40m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/23/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/23/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/23/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
Fastest Flights Monday
Fastest Buses Monday
-
LAN Airlines1h 16m08:09 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:25 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 8:09:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 9:25:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 1h 16m
-
LATAM Brasil1h 16m08:09 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:25 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 8:09:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 9:25:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 1h 16m
-
JetSmart1h 20m09:00 PMLa Florida, La Serena AirportLa Florida, La Serena Airport10:20 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 9:00:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/24/2026 10:20:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 1h 20m
-
LAN Perú20h 45m09:45 AMLa Florida, La Serena AirportLa Florida, La Serena Airport6:30 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 9:45:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/25/2026 6:30:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 20h 45m
-
Sky Airline21h 32m010:28 AMLa Florida, La Serena AirportLa Florida, La Serena Airport8:00 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/24/2026 10:28:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/25/2026 8:00:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 21h 32m
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/24/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/24/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
FlixBus11h 35m05:10 PMLa SerenaCentral Bus Station4:45 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/24/2026 5:10:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 4:45:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/24/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/25/2026 6:40:00 AM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/24/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/24/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
Fastest Flights Tuesday
Fastest Buses Tuesday
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/25/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/25/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/25/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 1:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 11h 35m
-
Cormar Bus11h 40m05:35 AMLa SerenaCentral Bus Station5:15 PMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/25/2026 5:35:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 3/25/2026 5:15:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 11h 40m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/25/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/25/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
Fastest Buses Wednesday
-
LAN Airlines1h 16m04:59 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:15 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 4:59:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:15:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 1h 16m
-
LATAM Brasil1h 16m04:59 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:15 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 4:59:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 6:15:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 16m
-
JetSmart1h 20m06:37 PMLa Florida, La Serena AirportLa Florida, La Serena Airport7:57 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 6:37:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 7:57:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 1h 20m
-
Sky Airline6h 23m02:55 PMLa Florida, La Serena AirportLa Florida, La Serena Airport9:18 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 2:55:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/26/2026 9:18:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 6h 23m
-
LAN Perú18h 27m012:04 PMLa Florida, La Serena AirportLa Florida, La Serena Airport6:31 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/26/2026 12:04:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 6:31:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 27m
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/26/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/26/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/26/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/26/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/26/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/26/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
Fastest Flights Thursday
Fastest Buses Thursday
-
LATAM Brasil1h 16m03:57 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:13 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 3:57:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 16m
-
LAN Airlines1h 16m03:57 PMLa Florida, La Serena AirportLa Florida, La Serena Airport5:13 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 3:57:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:13:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 1h 16m
-
JetSmart1h 20m09:59 AMLa Florida, La Serena AirportLa Florida, La Serena Airport11:19 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 9:59:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 11:19:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 1h 20m
-
Sky Airline8h 6m09:40 AMLa Florida, La Serena AirportLa Florida, La Serena Airport5:46 PMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 9:40:00 AM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/27/2026 5:46:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 8h 6m
-
LAN Perú15h 58m05:01 PMLa Florida, La Serena AirportLa Florida, La Serena Airport8:59 AMAndrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 3/27/2026 5:01:00 PM to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 3/28/2026 8:59:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 15h 58m
-
Pluss Chile10h 45m012:20 AMLa SerenaCentral Bus Station11:05 AMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 3/27/2026 12:20:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 11:05:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 10h 45m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/27/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 1:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 11h 35m
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/27/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 1:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 11h 35m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/27/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 6:40:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 40m
-
Cikbus Elité11h 45m05:15 AMLa SerenaCentral Bus Station5:00 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 3/27/2026 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/27/2026 5:00:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 45m
Fastest Flights Friday
Fastest Buses Friday
-
Nueva Andimar Vip11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 3/28/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 11h 35m
-
FlixBus11h 35m02:00 PMLa SerenaCentral Bus Station1:35 AMAntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 3/28/2026 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/29/2026 1:35:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 11h 35m
-
Cormar Bus11h 40m07:00 PMLa SerenaCentral Bus Station6:40 AMAntofagastaCamus Bus Station0Premium EconomyA Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 3/28/2026 7:00:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 3/29/2026 6:40:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 11h 40m
-
Pullman San Andres12h 10m03:00 AMLa SerenaCentral Bus Station3:10 PMAntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 3/28/2026 3:00:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 3/28/2026 3:10:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 12h 10m
-
Pullman Bus13h 5m03:30 AMLa SerenaEl Sto, 10604:35 PMAntofagastaCamus Bus Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 3/28/2026 3:30:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 3/28/2026 4:35:00 PM. 50 First Class ticket for $45 per person are available. Travel duration is 13h 5m
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from La Serena to Antofagasta
What are the most popular stations in La Serena and Antofagasta?
In La Serena, you will usually depart from Avda. Fco de Aguirre Station, Central Bus Station or El Sto, 1060, while in Antofagasta you will be arriving at Maipú, Camus Bus Station or Carlos Oviedo Cavada Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Antofagasta from La Serena? With 8 connections between 9 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between La Serena and Antofagasta, you can pay as low as $6 with a Bus from Nueva Andimar Vip.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Airlines: you will get to Antofagasta in just 1h 16m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting La Serena and Antofagasta are FlixBus, Cormar Bus and Pluss Chile, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in La Serena and Antofagasta is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Florida, La Serena Airport or to La Negra, and look at flights from La Florida, La Serena Airport, and landing at Andrés Sabella Gálvez, Antofagasta Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from La Serena to Antofagasta?
The most popular companies between La Serena and Antofagasta, are FlixBus, Cormar Bus and Pluss Chile. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Cormar Bus, Pluss Chile and 4 more.
Airlines: JetSmart, Sky Airline, LAN Perú and 2 more.
All you need to know when you travel from La Serena to Antofagasta
Check all information on comfort and services on all modes of transports from La Serena to Antofagasta. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from La Serena to Antofagasta
How can I reach Antofagasta from La Serena?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Antofagasta from La Serena.
How far is Antofagasta from La Serena?
The distance between La Serena and Antofagasta is 435.4 miles.
What is the most ecofriendly mode of transport between La Serena and Antofagasta?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 119 kgs, and a flight 172 kgs.
What is the cheapest mode of transport from La Serena to Antofagasta?
You can get to Antofagasta with just $6 by taking a Bus from Nueva Andimar Vip.
What is the fastest way to get from La Serena to Antofagasta?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Antofagasta in just 1h 16m with a Flight from LAN Airlines.
More routes to La Serena and to Antofagasta
Looking for more options? Here you can see the most popular routes to La Serena and to Antofagasta. Simply click on a connection, and you’ll find all the details about the route!
