Bus from La Serena to Antofagasta from $20

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Compare all timetables for the bus from La Serena to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from La Serena to Antofagasta from various bus operators like Pluss Chile, Cikbus Elité or Pullman San Andres for the next days.

today
from $20
tomorrow
from $24
Saturday
from $20
Sunday
from $24
Monday
from $28
Tuesday
from $24
Wednesday
from $24

Cheapest bus trips today

Prices are for one way and one person
  • Turbus
    11h 15m
    0
    5:40 PM
    La Serena
    Bus Stop
    4:55 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $20
  • Pluss Chile
    11h 35m
    0
    6:00 AM
    La Serena
    Bus Station
    5:35 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $24
  • Nueva Andimar Vip
    11h 45m
    0
    5:10 PM
    La Serena
    Bus Station
    4:55 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $28
  • Cikbus Elité
    11h 45m
    0
    4:00 PM
    La Serena
    Bus Station
    3:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman San Andres
    11h 30m
    0
    10:00 PM
    La Serena
    Bus Station
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Turbus
    11h 30m
    0
    6:10 PM
    La Serena
    Bus Stop
    5:40 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $24
  • Pluss Chile
    10h 45m
    0
    2:00 AM
    La Serena
    Bus Station
    12:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Nueva Andimar Vip
    11h 45m
    0
    2:00 PM
    La Serena
    Bus Station
    1:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $28
  • Cikbus Elité
    11h 30m
    0
    2:30 AM
    La Serena
    Bus Station
    2:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman San Andres
    11h 30m
    0
    10:00 PM
    La Serena
    Bus Station
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32

Cheapest bus trips Saturday

Prices are for one way and one person
  • Turbus
    12h 15m
    0
    5:55 AM
    La Serena
    Bus Stop
    6:10 PM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $20
  • Nueva Andimar Vip
    11h 45m
    0
    2:00 PM
    La Serena
    Bus Station
    1:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $26
  • Cikbus Elité
    11h 30m
    0
    2:30 AM
    La Serena
    Bus Station
    2:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman San Andres
    11h 30m
    0
    10:00 PM
    La Serena
    Bus Station
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32
  • Cormar Bus
    10h 30m
    0
    11:45 PM
    La Serena
    Bus Station
    10:15 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cormar Bus
    First Class
    $35

Cheapest bus trips Sunday

Prices are for one way and one person
  • Pluss Chile
    10h 45m
    0
    2:00 AM
    La Serena
    Bus Station
    12:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $24
  • Turbus
    11h 55m
    0
    9:10 AM
    La Serena
    Bus Stop
    9:05 PM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $29
  • Cikbus Elité
    11h 45m
    0
    4:00 PM
    La Serena
    Bus Station
    3:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman San Andres
    11h 30m
    0
    10:00 PM
    La Serena
    Bus Station
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32
  • Ramos Cholele
    10h 30m
    0
    3:30 PM
    La Serena
    El Sto, 1060
    2:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    $32

Cheapest bus trips Monday

Prices are for one way and one person
  • Nueva Andimar Vip
    11h 45m
    0
    2:00 PM
    La Serena
    Bus Station
    1:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $28
  • Pluss Chile
    10h 45m
    0
    2:00 AM
    La Serena
    Bus Station
    12:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Turbus
    11h 30m
    0
    6:10 PM
    La Serena
    Bus Stop
    5:40 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $28
  • Cikbus Elité
    11h 35m
    0
    2:45 AM
    La Serena
    Bus Station
    2:20 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman San Andres
    11h 30m
    0
    10:00 PM
    La Serena
    Bus Station
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32
  • Did you know that if you travel from La Serena to Antofagasta via Coquimbo, you can save more than $0? You will find the corresponding connections below.
    • Save more than 1%
      12h 5m
      La Serena
      7 mi
      8:20 PM
      Coquimbo
      La Cantera Bus Stop
      8:25 AM
      Antofagasta
      Terminal Buses Camus
      0 mi
      Premium Economy
      $28

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Turbus
    11h 30m
    0
    6:10 PM
    La Serena
    Bus Stop
    5:40 AM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $24
  • Pluss Chile
    10h 45m
    0
    2:00 AM
    La Serena
    Bus Station
    12:45 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Pullman San Andres
    11h 30m
    0
    6:00 AM
    La Serena
    Bus Station
    5:30 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32
  • Ramos Cholele
    10h 30m
    0
    3:30 PM
    La Serena
    El Sto, 1060
    2:00 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    $32
  • Cormar Bus
    10h 30m
    0
    7:40 PM
    La Serena
    Bus Station
    6:10 AM
    Antofagasta
    Terminal Buses Camus
    0
    Cormar Bus
    First Class
    $37

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Turbus
    11h 55m
    0
    9:10 AM
    La Serena
    Bus Stop
    9:05 PM
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    $24
  • Pluss Chile
    10h 45m
    0
    1:50 AM
    La Serena
    Bus Station
    12:35 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    $28
  • Nueva Andimar Vip
    11h 45m
    0
    2:00 PM
    La Serena
    Bus Station
    1:45 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    $28
  • Cikbus Elité
    11h 30m
    0
    2:30 AM
    La Serena
    Bus Station
    2:00 PM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    $30
  • Pullman San Andres
    11h 30m
    0
    10:00 PM
    La Serena
    Bus Station
    9:30 AM
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    $32

Frequency of bus connections between La Serena and Antofagasta

See here how frequent the connections between La Serena and Antofagasta are, during different times and days of the week.
Monday is the busiest day, with more than 121 daily buses from La Serena to Antofagasta. Saturday has instead the fewest connections, with only 64 daily coaches between La Serena and Antofagasta.
The busiest time of the day is the Evening, with 295 buses from La Serena to Antofagasta, while Morning sees the fewest connections between La Serena and Antofagasta, with 68 offers.

Facts about the bus from La Serena to Antofagasta

Compare all providers like Pluss Chile, Cikbus Elité and Pullman San Andres that travel 93 times every day by bus from La Serena to Antofagasta in one click! Book your bus ticket from La Serena to Antofagasta starting from $20!

Cheapest Bus $20
Fastest Bus 10h 20m
Earliest Bus 5:15 AM
Latest Bus 11:45 PM
Daily Bus Routes 93 Ø
Distance 435.4 miles
Bus Companies Pluss Chile, Cikbus Elité, Pullman San Andres, Pullman Bus, Turbus, Cormar Bus, Nueva Andimar Vip and Ramos Cholele

Cheapest bus connections from La Serena to Antofagasta

Every day, 93 buses from 8 bus companies leave La Serena for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/26/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
Thursday 06/26
$20
Friday 06/27
$33
Saturday 06/28
$20
Sunday 06/29
$29
Monday 06/30
$27
Tuesday 07/01
$24
Wednesday 07/02
$25
Thursday 07/03
$24
Friday 07/04
$32
Saturday 07/05
$24
Sunday 07/06
$25
Monday 07/07
$24
Tuesday 07/08
$22
Wednesday 07/09
$19
Thursday 07/10
$18
Friday 07/11
$19
Saturday 07/12
$18
Sunday 07/13
$22
Monday 07/14
$22
Tuesday 07/15
$22
Wednesday 07/16
$22
Thursday 07/17
$18
Friday 07/18
$32
Saturday 07/19

The cheapest time to travel from La Serena to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Antofagasta, for the next 30 days.
With a price starting from $20, Thursday is the cheapest day for a bus from La Serena to Antofagasta. Monday instead is the most expensive day with prices starting from $28.
Morning is the cheapest day time for bus tickets from La Serena to Antofagasta, with $20. Morning is the most expensive time of the day with prices starting from $20.

How to save money travelling from La Serena to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from La Serena to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from La Serena to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from La Serena to Antofagasta are also emptier.

Latest reviews for bus companies on the route La Serena - Antofagasta

Cormar Bus
Scarleth, 6/15/2025
Aún voy a bordo, pero no podía dejar pasar la oportunidad de felicitar la amabilidad del personal del bus, si bien cumplen con todo los estándares de calidad que ofrecen, mi asiento tuvo un defecto y ... Aún voy a bordo, pero no podía dejar pasar la oportunidad de felicitar la amabilidad del personal del bus, si bien cumplen con todo los estándares de calidad que ofrecen, mi asiento tuvo un defecto y no se podia tirar para atrás, el auxiliar fué informado y de inmediato me resolvió usar otro asiento aunque esté fuera mas caro, incluso nos movió junto a mi pareja para que no estuvieramos separados aunque el asiento de él estaba bien. Muy agradecida por la atención desde que me subí hasta ahora que estoy rumbo a mi hogar. Muchas gracias, no todas las lineas se toman en serio el servicio al cliente, lo digo por experiencia. Un abrazo

All bus stations and stops in La Serena and Antofagasta

In the map below, you can see where to find all bus stations in La Serena and Antofagasta.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from La Serena to Antofagasta? Compare all modes of transports from La Serena to Antofagasta.

Service and Comfort on the bus from La Serena to Antofagasta

Want to know which seat classes are available on the buses from La Serena to Antofagasta? Or which bus companies serve the route La Serena to Antofagasta? Below you will find answers to your questions.

FAQs about the La Serena to Antofagasta bus

How much does a La Serena Antofagasta bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $20 and takes 11h 15m to reach Antofagasta. Compare offers to save money!

How much could I save by comparing buses from La Serena to Antofagasta?

This route is offered by 8 companies with a range of ticket prices between $20 and $52. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Antofagasta.

On average, how many connections are available from La Serena to Antofagasta each day?

Every day, the La Serena to Antofagasta bus route is served by approximately 93 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from La Serena to Antofagasta take?

The fastest bus from La Serena to Antofagasta is offered by Cormar Bus and takes 10h 20m. Bus tickets for this connection cost $33. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from La Serena to Antofagasta?

The earliest bus arriving in Antofagasta from La Serena starts at 5:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from La Serena to Antofagasta?

The latest bus trip departing from La Serena for Antofagasta starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the La Serena Antofagasta route?

When traveling by bus from La Serena to Antofagasta, passengers can travel with Pluss Chile, Cikbus Elité and Pullman San Andres. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between La Serena and Antofagasta?

You can check all the direct connections between La Serena and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Cikbus Elité and Pullman San Andres.

What can I take with me on the La Serena to Antofagasta bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the La Serena Antofagasta bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Antofagasta on your planned travel date.

Available seat classes which are offered on the bus route La Serena to Antofagasta

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Antofagasta

Here’s an overview of the most popular bus routes to La Serena and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!

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