Bus from La Serena to Antofagasta from $26

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Compare all timetables for the bus from La Serena to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from La Serena to Antofagasta from various bus operators like Pluss Chile, Pullman San Andres or Pullman Bus for the next days.

today
$31
tomorrow
$31
Saturday
$28
Sunday
$33
Monday
$31
Tuesday
$28
Wednesday
$28

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 11h 35m 2:00 PM La Serena Central Bus Station 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $31
Pullman San Andres 12h 10m 10:00 PM La Serena Central Bus Station 10:10 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Cormar Bus 10h 30m 7:45 PM La Serena Central Bus Station 6:15 AM Antofagasta Carlos Oviedo Cavada Bus Station  First Class $38
Pullman Bus 11h 35m 9:15 AM La Serena El Sto, 1060 8:50 PM Antofagasta Camus Bus Station  First Class $39
Ramos Cholele 11h 0m 6:00 PM La Serena El Sto, 1060 5:00 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $56
  • Did you know that if you travel from La Serena to Antofagasta via Ovalle, you can save more than $3? You can find the corresponding connections below.
    • Serena Mar
      15h 30m
      0
      12:05 PM
      La Serena
      Central Bus Station
      1:35 PM
      Ovalle
      Bus Stop
      0
      Serena Mar
      Premium Economy
      $6
      • Waiting Time 0h 55m
    • FlixBus
      13h 5m
      0
      2:30 PM
      Ovalle
      Bus Station
      3:35 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      FlixBus
      Economy
      $23
    Travel time is 5h 0m longer, but you will save $3

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 35m 2:00 PM La Serena Central Bus Station 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $31
Pullman San Andres 12h 10m 3:00 AM La Serena Central Bus Station 3:10 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Cikbus Elité 11h 0m 11:00 PM La Serena Central Bus Station 10:00 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Cormar Bus 11h 40m 7:00 PM La Serena Central Bus Station 6:40 AM Antofagasta Camus Bus Station  Premium Economy $37
Pullman Bus 12h 50m 1:30 AM La Serena El Sto, 1060 2:20 PM Antofagasta Camus Bus Station  First Class $39
  • Did you know that if you travel from La Serena to Antofagasta via Ovalle, you can save more than $3? You can find the corresponding connections below.
    • Serena Mar
      15h 30m
      0
      12:05 PM
      La Serena
      Central Bus Station
      1:35 PM
      Ovalle
      Bus Stop
      0
      Serena Mar
      Premium Economy
      $6
      • Waiting Time 0h 55m
    • FlixBus
      13h 5m
      0
      2:30 PM
      Ovalle
      Bus Station
      3:35 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      FlixBus
      Economy
      $23
    Travel time is 4h 30m longer, but you will save $3

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 10h 45m 9:05 PM La Serena Central Bus Station 7:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $28
Nueva Andimar Vip 11h 35m 2:00 PM La Serena Central Bus Station 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $31
Pullman San Andres 12h 10m 3:00 AM La Serena Central Bus Station 3:10 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Cormar Bus 11h 40m 7:00 PM La Serena Central Bus Station 6:40 AM Antofagasta Camus Bus Station  Premium Economy $37
Pullman Bus 12h 50m 1:30 AM La Serena El Sto, 1060 2:20 PM Antofagasta Camus Bus Station  First Class $39

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 11h 35m 2:00 PM La Serena Central Bus Station 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $33
FlixBus 11h 35m 4:00 PM La Serena Central Bus Station 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $33
Cormar Bus 11h 40m 5:35 AM La Serena Central Bus Station 5:15 PM Antofagasta Camus Bus Station  Premium Economy $33
Pullman San Andres 12h 10m 3:00 AM La Serena Central Bus Station 3:10 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Pullman Bus 12h 50m 1:30 AM La Serena El Sto, 1060 2:20 PM Antofagasta Camus Bus Station  First Class $39
  • Did you know that if you travel from La Serena to Antofagasta via Ovalle, you can save more than $5? You can find the corresponding connections below.
    • Serena Mar
      15h 30m
      0
      12:05 PM
      La Serena
      Central Bus Station
      1:35 PM
      Ovalle
      Bus Stop
      0
      Serena Mar
      Premium Economy
      $6
      • Waiting Time 0h 55m
    • FlixBus
      13h 5m
      0
      2:30 PM
      Ovalle
      Bus Station
      3:35 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      FlixBus
      Economy
      $23
    Travel time is 3h 55m longer, but you will save $5

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 11h 35m 7:15 PM La Serena Central Bus Station 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $31
FlixBus 11h 35m 4:00 PM La Serena Central Bus Station 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $34
Pullman San Andres 12h 10m 3:00 AM La Serena Central Bus Station 3:10 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Cormar Bus 11h 40m 7:00 PM La Serena Central Bus Station 6:40 AM Antofagasta Camus Bus Station  Premium Economy $37
Cikbus Elité 11h 45m 5:15 AM La Serena Central Bus Station 5:00 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $38
  • Did you know that if you travel from La Serena to Antofagasta via Ovalle, you can save more than $3? You can find the corresponding connections below.
    • Serena Mar
      15h 30m
      0
      12:05 PM
      La Serena
      Central Bus Station
      1:35 PM
      Ovalle
      Bus Stop
      0
      Serena Mar
      Premium Economy
      $6
      • Waiting Time 0h 55m
    • FlixBus
      13h 5m
      0
      2:30 PM
      Ovalle
      Bus Station
      3:35 AM
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      FlixBus
      Economy
      $23
    Travel time is 3h 55m longer, but you will save $3

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 35m 5:10 PM La Serena Central Bus Station 4:45 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $28
Nueva Andimar Vip 11h 35m 2:00 PM La Serena Central Bus Station 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $29
Cikbus Elité 10h 40m 8:35 PM La Serena Central Bus Station 7:15 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Pullman San Andres 12h 10m 3:00 AM La Serena Central Bus Station 3:10 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Cormar Bus 11h 40m 7:00 PM La Serena Central Bus Station 6:40 AM Antofagasta Camus Bus Station  Premium Economy $37

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 35m 2:00 PM La Serena Central Bus Station 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $28
Nueva Andimar Vip 11h 35m 7:15 PM La Serena Central Bus Station 6:50 AM Antofagasta Carlos Oviedo Cavada Bus Station  Economy $29
Cormar Bus 11h 40m 5:35 AM La Serena Central Bus Station 5:15 PM Antofagasta Camus Bus Station  Premium Economy $33
Cikbus Elité 11h 0m 11:00 PM La Serena Central Bus Station 10:00 AM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36
Pullman San Andres 12h 10m 3:00 AM La Serena Central Bus Station 3:10 PM Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy $36

Best Price Offer: The price for the cheapest bus from La Serena to Antofagasta is $26 on 5/29/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between La Serena and Antofagasta

See here how frequent the connections between La Serena and Antofagasta are, during different times and days of the week.
Monday is the busiest day, with more than 122 daily buses from La Serena to Antofagasta. Thursday has instead the fewest connections, with only 33 daily coaches between La Serena and Antofagasta.
The busiest time of the day is the Evening, with 263 buses from La Serena to Antofagasta, while Morning sees the fewest connections between La Serena and Antofagasta, with 52 offers.

Facts about the bus from La Serena to Antofagasta

Compare all providers like Pluss Chile, Pullman San Andres and Pullman Bus that travel 90 times every day by bus from La Serena to Antofagasta in one click! Book your bus ticket from La Serena to Antofagasta starting from $26!

Cheapest Bus $26
Fastest Bus 10h 30m
Earliest Bus 9:00 AM
Latest Bus 11:45 PM
Daily Bus Routes 90 Ø
Distance 435.4 miles
Bus Companies Pluss Chile, Pullman San Andres, Pullman Bus, Cormar Bus, Cikbus Elité, Nueva Andimar Vip, FlixBus and Ramos Cholele

Cheapest bus connections from La Serena to Antofagasta

Every day, 90 buses from 8 bus companies leave La Serena for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/03
Monday 05/04
Tuesday 05/05
Wednesday 05/06
Thursday 05/07
$31
Friday 05/08
$31
Saturday 05/09
$31
Sunday 05/10
$39
Monday 05/11
$31
Tuesday 05/12
$28
Wednesday 05/13
$28
Thursday 05/14
$29
Friday 05/15
$29
Saturday 05/16
$28
Sunday 05/17
$31
Monday 05/18
$29
Tuesday 05/19
$31
Wednesday 05/20
$33
Thursday 05/21
$33
Friday 05/22
$31
Saturday 05/23
$31
Sunday 05/24
$30
Monday 05/25
$28
Tuesday 05/26
$28
Wednesday 05/27
$26
Thursday 05/28
$27
Friday 05/29
$26
Saturday 05/30

The cheapest time to travel from La Serena to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Antofagasta, for the next 30 days.
With a price starting from $25, Monday is the cheapest day for a bus from La Serena to Antofagasta. Sunday instead is the most expensive day with prices starting from $30.
Night is the cheapest day time for bus tickets from La Serena to Antofagasta, with $25. Morning is the most expensive time of the day with prices starting from $39.

How to save money travelling from La Serena to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from La Serena to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from La Serena to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from La Serena to Antofagasta are also emptier.

Beloved bus companies from La Serena to Antofagasta

These are the most booked bus companies between La Serena to Antofagasta from our users.

Pullman San Andres from La Serena to Antofagasta

Pullman San Andres

Here you will find the key facts about the Pullman San Andres bus route La Serena to Antofagasta:

Cheapest Price $36
Fastest Bus 11h 10m
Earliest Bus 2:30 PM
Last Bus 11:30 PM
Daily Connections 24 Ø
Found on 5/7/2026

Latest reviews for bus companies on the route La Serena - Antofagasta

Cormar Bus
Fide Jiménez , 4/26/2026
Pésimo servicio. Pasaje a las 23:45 horas el bus no llego. A esa hora dijeron que saldría otro a las 00:40 horas que tampoco llegó. Cuando fueron mis hijas a la ventanilla las personas las atendiero ... Pésimo servicio. Pasaje a las 23:45 horas el bus no llego. A esa hora dijeron que saldría otro a las 00:40 horas que tampoco llegó. Cuando fueron mis hijas a la ventanilla las personas las atendieron super mal, cero consideración con los pasajeros, prepotentes y de mal genio. El bus llegó a una de la mañana una falta de respeto con las personas que pagamos por un servicio y que no se cumple. Pagar por impuntualidad, mal rato, espera, y no poder cumplir con los compromisos contraídos en Antofagasta. Una vergüenza esta empresa.
Cormar Bus
Scarleth, 6/15/2025
Aún voy a bordo, pero no podía dejar pasar la oportunidad de felicitar la amabilidad del personal del bus, si bien cumplen con todo los estándares de calidad que ofrecen, mi asiento tuvo un defecto y ... Aún voy a bordo, pero no podía dejar pasar la oportunidad de felicitar la amabilidad del personal del bus, si bien cumplen con todo los estándares de calidad que ofrecen, mi asiento tuvo un defecto y no se podia tirar para atrás, el auxiliar fué informado y de inmediato me resolvió usar otro asiento aunque esté fuera mas caro, incluso nos movió junto a mi pareja para que no estuvieramos separados aunque el asiento de él estaba bien. Muy agradecida por la atención desde que me subí hasta ahora que estoy rumbo a mi hogar. Muchas gracias, no todas las lineas se toman en serio el servicio al cliente, lo digo por experiencia. Un abrazo

All bus stations and stops in La Serena and Antofagasta

In the map below, you can see where to find all bus stations in La Serena and Antofagasta.

Service and Comfort on the bus from La Serena to Antofagasta

Want to know which seat classes are available on the buses from La Serena to Antofagasta? Or which bus companies serve the route La Serena to Antofagasta? Below you will find answers to your questions.

FAQs about the La Serena to Antofagasta bus

How much does a La Serena Antofagasta bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $26 and takes 10h 45m to reach Antofagasta. Compare offers to save money!

How much could I save by comparing buses from La Serena to Antofagasta?

This route is offered by 8 companies with a range of ticket prices between $26 and $62. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Antofagasta.

On average, how many connections are available from La Serena to Antofagasta each day?

Every day, the La Serena to Antofagasta bus route is served by approximately 90 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from La Serena to Antofagasta take?

The fastest bus from La Serena to Antofagasta is offered by Cormar Bus and takes 10h 30m. Bus tickets for this connection cost $39. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from La Serena to Antofagasta?

The earliest bus arriving in Antofagasta from La Serena starts at 9:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from La Serena to Antofagasta?

The latest bus trip departing from La Serena for Antofagasta starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the La Serena Antofagasta route?

When traveling by bus from La Serena to Antofagasta, passengers can travel with Pluss Chile, Pullman San Andres and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between La Serena and Antofagasta?

You can check all the direct connections between La Serena and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Pullman San Andres and Pullman Bus.

What can I take with me on the La Serena to Antofagasta bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the La Serena Antofagasta bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Antofagasta on your planned travel date.

How does CheckMyBus find the best bus deals from La Serena to Antofagasta?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 90 daily trips between La Serena and Antofagasta. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from La Serena to Antofagasta?

Prices and availability for 90 trips between La Serena and Antofagasta change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route La Serena to Antofagasta

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Antofagasta

Here’s an overview of the most popular bus routes to La Serena and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!
Quilpué to La Serena bus Quilpué to La Serena bus
Bus from Concepción to La Serena Bus from Concepción to La Serena
Buses from Ovalle to La Serena Buses from Ovalle to La Serena
Bus Talca, ML to La Serena Bus Talca, ML to La Serena
Buses to Antofagasta from Coquimbo Buses to Antofagasta from Coquimbo
Buses to Antofagasta from Copiapó Buses to Antofagasta from Copiapó
Buses Oruro to Antofagasta Buses Oruro to Antofagasta
Bus from Tocopilla to Antofagasta Bus from Tocopilla to Antofagasta
CheckMyBus › Buses in Chile › Bus to La Serena › Bus to Antofagasta

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