Compare all timetables for the bus from La Serena to Antofagasta
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 11h 35m | 2:00 PM | La Serena | Central Bus Station | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $24 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 12/5/2025 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/6/2025 1:35:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 35m
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| Cikbus Elité | 11h 30m | 2:15 AM | La Serena | Central Bus Station | 1:45 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $27 |
A Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 12/5/2025 2:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/5/2025 1:45:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 30m
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| Cormar Bus | 11h 30m | 6:40 PM | La Serena | Central Bus Station | 6:10 AM | Antofagasta | Camus Bus Station | Premium Economy | $28 |
A Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 12/5/2025 6:40:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 12/6/2025 6:10:00 AM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 30m
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| Pluss Chile | 10h 45m | 1:50 AM | La Serena | Central Bus Station | 12:35 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $28 |
A Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 12/5/2025 1:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/5/2025 12:35:00 PM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 10h 45m
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| Pullman San Andres | 12h 10m | 1:30 PM | La Serena | Central Bus Station | 1:40 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $33 |
A Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 12/5/2025 1:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/6/2025 1:40:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 11h 35m | 2:00 PM | La Serena | Central Bus Station | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $24 |
A Bus from FlixBus goes from Central Bus Station, La Serena (Chile) at 12/6/2025 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/7/2025 1:35:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 35m
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| Nueva Andimar Vip | 11h 35m | 5:10 PM | La Serena | Central Bus Station | 4:45 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $24 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 12/6/2025 5:10:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/7/2025 4:45:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 35m
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| Pullman San Andres | 12h 10m | 10:00 PM | La Serena | Central Bus Station | 10:10 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $33 |
A Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 12/6/2025 10:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/7/2025 10:10:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 11h 0m | 1:35 AM | La Serena | Central Bus Station | 12:35 PM | Antofagasta | Camus Bus Station | First Class | $37 |
A Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 12/6/2025 1:35:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 12/6/2025 12:35:00 PM. 50 First Class ticket for $37 per person are available. Travel duration is 11h 0m
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| Pullman Bus | 13h 5m | 3:30 AM | La Serena | El Sto, 1060 | 4:35 PM | Antofagasta | Camus Bus Station | First Class | $38 |
A Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 12/6/2025 3:30:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 12/6/2025 4:35:00 PM. 50 First Class ticket for $38 per person are available. Travel duration is 13h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 11h 35m | 2:00 PM | La Serena | Central Bus Station | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $24 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 12/7/2025 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/8/2025 1:35:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 35m
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| Cikbus Elité | 11h 30m | 3:20 PM | La Serena | Central Bus Station | 2:50 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $27 |
A Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 12/7/2025 3:20:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/8/2025 2:50:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 30m
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| Pluss Chile | 10h 45m | 1:50 AM | La Serena | Central Bus Station | 12:35 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $28 |
A Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 12/7/2025 1:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/7/2025 12:35:00 PM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 10h 45m
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| Cormar Bus | 11h 30m | 6:40 PM | La Serena | Central Bus Station | 6:10 AM | Antofagasta | Camus Bus Station | Premium Economy | $29 |
A Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 12/7/2025 6:40:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 12/8/2025 6:10:00 AM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 11h 30m
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| Pullman San Andres | 12h 10m | 10:00 PM | La Serena | Central Bus Station | 10:10 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $33 |
A Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 12/7/2025 10:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/8/2025 10:10:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 11h 35m | 2:00 PM | La Serena | Central Bus Station | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $28 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 12/8/2025 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/9/2025 1:35:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 11h 35m
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| Pullman San Andres | 12h 10m | 10:00 PM | La Serena | Central Bus Station | 10:10 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $33 |
A Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 12/8/2025 10:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/9/2025 10:10:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 12h 10m
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| Pluss Chile | 10h 45m | 1:50 AM | La Serena | Central Bus Station | 12:35 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $36 |
A Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 12/8/2025 1:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/8/2025 12:35:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 10h 45m
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| Cormar Bus | 11h 0m | 12:40 AM | La Serena | Central Bus Station | 11:40 AM | Antofagasta | Camus Bus Station | First Class | $38 |
A Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 12/8/2025 12:40:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 12/8/2025 11:40:00 AM. 50 First Class ticket for $38 per person are available. Travel duration is 11h 0m
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| Pullman Bus | 13h 5m | 3:30 AM | La Serena | El Sto, 1060 | 4:35 PM | Antofagasta | Camus Bus Station | First Class | $38 |
A Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 12/8/2025 3:30:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 12/8/2025 4:35:00 PM. 50 First Class ticket for $38 per person are available. Travel duration is 13h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 11h 35m | 2:00 PM | La Serena | Central Bus Station | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $24 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 12/9/2025 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/10/2025 1:35:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 35m
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| Cikbus Elité | 11h 45m | 5:15 AM | La Serena | Central Bus Station | 5:00 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $28 |
A Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 12/9/2025 5:15:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/9/2025 5:00:00 PM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 11h 45m
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| Cormar Bus | 11h 30m | 6:40 PM | La Serena | Central Bus Station | 6:10 AM | Antofagasta | Camus Bus Station | Premium Economy | $29 |
A Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 12/9/2025 6:40:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 12/10/2025 6:10:00 AM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 11h 30m
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| Pullman San Andres | 12h 10m | 10:00 PM | La Serena | Central Bus Station | 10:10 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $33 |
A Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 12/9/2025 10:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/10/2025 10:10:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 12h 10m
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| Pullman Bus | 11h 30m | 3:30 PM | La Serena | El Sto, 1060 | 3:00 AM | Antofagasta | Camus Bus Station | First Class | $37 |
A Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 12/9/2025 3:30:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 12/10/2025 3:00:00 AM. 50 First Class ticket for $37 per person are available. Travel duration is 11h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 11h 35m | 2:00 PM | La Serena | Central Bus Station | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $24 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 12/10/2025 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/11/2025 1:35:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 35m
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| Cikbus Elité | 11h 35m | 2:45 AM | La Serena | Central Bus Station | 2:20 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $27 |
A Bus from Cikbus Elité goes from Central Bus Station, La Serena (Chile) at 12/10/2025 2:45:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/10/2025 2:20:00 PM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 11h 35m
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| Pluss Chile | 10h 45m | 1:50 AM | La Serena | Central Bus Station | 12:35 PM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $28 |
A Bus from Pluss Chile goes from Central Bus Station, La Serena (Chile) at 12/10/2025 1:50:00 AM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/10/2025 12:35:00 PM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 10h 45m
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| Pullman San Andres | 12h 10m | 8:30 PM | La Serena | Central Bus Station | 8:40 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $33 |
A Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 12/10/2025 8:30:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/11/2025 8:40:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 11h 10m | 3:30 PM | La Serena | Central Bus Station | 2:40 AM | Antofagasta | Camus Bus Station | First Class | $36 |
A Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 12/10/2025 3:30:00 PM to Camus Bus Station, Antofagasta (Chile) arriving at 12/11/2025 2:40:00 AM. 50 First Class ticket for $36 per person are available. Travel duration is 11h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 11h 35m | 2:00 PM | La Serena | Central Bus Station | 1:35 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Economy | $24 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, La Serena (Chile) at 12/11/2025 2:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/12/2025 1:35:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 11h 35m
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| Pullman San Andres | 12h 10m | 10:00 PM | La Serena | Central Bus Station | 10:10 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $33 |
A Bus from Pullman San Andres goes from Central Bus Station, La Serena (Chile) at 12/11/2025 10:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/12/2025 10:10:00 AM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 10h 30m | 7:45 PM | La Serena | Central Bus Station | 6:15 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | First Class | $37 |
A Bus from Cormar Bus goes from Central Bus Station, La Serena (Chile) at 12/11/2025 7:45:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/12/2025 6:15:00 AM. 50 First Class ticket for $37 per person are available. Travel duration is 10h 30m
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| Pullman Bus | 13h 5m | 3:30 AM | La Serena | El Sto, 1060 | 4:35 PM | Antofagasta | Camus Bus Station | First Class | $38 |
A Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 12/11/2025 3:30:00 AM to Camus Bus Station, Antofagasta (Chile) arriving at 12/11/2025 4:35:00 PM. 50 First Class ticket for $38 per person are available. Travel duration is 13h 5m
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| Ramos Cholele | 11h 0m | 6:00 PM | La Serena | El Sto, 1060 | 5:00 AM | Antofagasta | Carlos Oviedo Cavada Bus Station | Premium Economy | $98 |
A Bus from Ramos Cholele goes from El Sto, 1060, La Serena (Chile) at 12/11/2025 6:00:00 PM to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 12/12/2025 5:00:00 AM. 50 Premium Economy ticket for $98 per person are available. Travel duration is 11h 0m
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Best Price Offer: The price for the cheapest bus from La Serena to Antofagasta is $19 on 12/9/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between La Serena and Antofagasta
Facts about the bus from La Serena to Antofagasta
Compare all providers like Pluss Chile, Pullman San Andres and Pullman Bus that travel 78 times every day by bus from La Serena to Antofagasta in one click! Book your bus ticket from La Serena to Antofagasta starting from $19!
| Cheapest Bus | $19 |
| Fastest Bus | 10h 30m |
| Earliest Bus | 1:30 AM |
| Latest Bus | 11:45 PM |
| Daily Bus Routes | 78 Ø |
| Distance | 435.4 miles |
| Bus Companies | Pluss Chile, Pullman San Andres, Pullman Bus, Cikbus Elité, Cormar Bus, Nueva Andimar Vip, FlixBus and Ramos Cholele |
Cheapest bus connections from La Serena to Antofagasta
Every day, 78 buses from 8 bus companies leave La Serena for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.
The cheapest time to travel from La Serena to Antofagasta
How to save money travelling from La Serena to Antofagasta
Book the ticket from La Serena to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from La Serena to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from La Serena to Antofagasta are also emptier.Latest reviews for bus companies on the route La Serena - Antofagasta
All bus stations and stops in La Serena and Antofagasta
In the map below, you can see where to find all bus stations in La Serena and Antofagasta.
Compare the bus with other modes of transport
Service and Comfort on the bus from La Serena to Antofagasta
FAQs about the La Serena to Antofagasta bus
How much does a La Serena Antofagasta bus trip cost?
How much could I save by comparing buses from La Serena to Antofagasta?
On average, how many connections are available from La Serena to Antofagasta each day?
How long does a bus journey from La Serena to Antofagasta take?
What time is the first bus from La Serena to Antofagasta?
What time is the last bus from La Serena to Antofagasta?
Which bus companies operate the La Serena Antofagasta route?
Is there a direct bus between La Serena and Antofagasta?
What can I take with me on the La Serena to Antofagasta bus route?
What equipment is available for the La Serena Antofagasta bus route?
Available seat classes which are offered on the bus route La Serena to Antofagasta
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to La Serena and to Antofagasta
- Bus Routes to La Serena
- Alto Hospicio to La Serena bus
- Buses Arica, AP to La Serena
- Bus from Concepción to La Serena
- Buses to La Serena from Copiapó
- Bus Diego de Almagro - La Serena
- Buses Iquique - La Serena
- From La Calera to La Serena bus
- Buses to La Serena from Los Vilos
- Bus to La Serena from Mendoza
- Buses from Ovalle to La Serena
- Pozo Almonte to La Serena bus
- Quilpué to La Serena bus
- Buses Rancagua to La Serena
- San Juan, SJ to La Serena bus
- Buses Sierra Gorda to La Serena
- Bus Talca, ML to La Serena
- Bus Temuco to La Serena
- Bus from Tocopilla to La Serena
- Buses to La Serena from Valdivia
- Bus Vallenar to La Serena
- Bus Routes to Antofagasta
- Bus from Alto Hospicio to Antofagasta
- Buses Baquedano - Antofagasta
- Bus from Cochabamba to Antofagasta
- Buses to Antofagasta from Copiapó
- Buses to Antofagasta from Coquimbo
- Buses from La Calera to Antofagasta
- Buses from Los Vilos to Antofagasta
- Mejillones to Antofagasta bus
- Buses Oruro to Antofagasta
- Buses Ovalle to Antofagasta
- Bus to Antofagasta from Pozo Almonte
- Bus to Antofagasta from Salta
- Bus San Pedro de Atacama to Antofagasta
- Bus from Santiago, RM to Antofagasta
- Buses Sierra Gorda - Antofagasta
- Bus from Tocopilla to Antofagasta
- Bus to Antofagasta from Vallenar
- Buses from Viña del Mar to Antofagasta

