Bus from Mendoza to La Serena from $95

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Compare all timetables for the bus from Mendoza to La Serena

Here is a selection of the cheapest bus trips from the schedule from Mendoza to La Serena from various bus operators like CATA Internacional for the next days.

today
tomorrow
$95
Sunday
Monday
Tuesday
$95
Wednesday
Thursday
$95

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
CATA Internacional 11h 45m 8:15 PM Mendoza Bus Station 8:00 AM La Serena Central Bus Station  Premium Economy $95
CATA Internacional 11h 45m 8:16 PM Mendoza Bus Station 8:01 AM La Serena Avda. Fco de Aguirre Station  Business $95
  • Did you know that if you travel from Mendoza to La Serena via Santiago, RM, you can save more than $48? You can find the corresponding connections below.
    • Plataforma 10
      14h 15m
      0
      10:00 AM
      Mendoza
      Bus Station
      6:00 PM
      Santiago, RM
      Sur Bus Station
      0
      Plataforma 10
      Premium Economy
      $31
      • Waiting Time 0h 5m
    • Busbud
      6h 10m
      0
      6:05 PM
      Santiago, RM
      Los Libertadores Bus Stop
      12:15 AM
      La Serena
      Central Bus Station
      0
      Busbud
      Economy
      $16
    Travel time is 2h 30m longer, but you will save $48

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
CATA Internacional 11h 45m 8:15 PM Mendoza Bus Station 8:00 AM La Serena Central Bus Station  Premium Economy $95
  • Did you know that if you travel from Mendoza to La Serena via Santiago, RM, you can save more than $61? You can find the corresponding connections below.
    • CheckMyBus Brazil
      16h 55m
      0
      9:10 PM
      Mendoza
      Hotel Hyatt
      4:10 AM
      Santiago, RM
      Sur Bus Station
      0
      CheckMyBus Brazil
      Basic
      $13
      • Waiting Time 3h 35m
    • Recorrido CL
      6h 20m
      0
      7:45 AM
      Santiago, RM
      Sur Bus Station
      2:05 PM
      La Serena
      Central Bus Station
      0
      Recorrido CL
      Premium Economy
      $22
    Travel time is 5h 10m longer, but you will save $61

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
CATA Internacional 11h 45m 8:15 PM Mendoza Bus Station 8:00 AM La Serena Central Bus Station  Premium Economy $95
  • Did you know that if you travel from Mendoza to La Serena via Santiago, RM, you can save more than $61? You can find the corresponding connections below.
    • CheckMyBus Brazil
      16h 55m
      0
      9:10 PM
      Mendoza
      Hotel Hyatt
      4:10 AM
      Santiago, RM
      Sur Bus Station
      0
      CheckMyBus Brazil
      Basic
      $13
      • Waiting Time 3h 35m
    • Recorrido CL
      6h 20m
      0
      7:45 AM
      Santiago, RM
      Sur Bus Station
      2:05 PM
      La Serena
      Central Bus Station
      0
      Recorrido CL
      Premium Economy
      $22
    Travel time is 5h 10m longer, but you will save $61

Best Price Offer: The price for the cheapest bus from Mendoza to La Serena is $95 on 2/7/2026. Flexible travelers save on ticket prices.


Facts about the bus from Mendoza to La Serena

Compare all providers like CATA Internacional that travel 6 times every day by bus from Mendoza to La Serena in one click! Book your bus ticket from Mendoza to La Serena starting from $95!

Cheapest Bus $95
Fastest Bus 11h 45m
Earliest Bus 8:15 PM
Latest Bus 8:15 PM
Daily Bus Routes 6 Ø
Distance 250.5 miles
Bus Companies CATA Internacional

Cheapest bus connections from Mendoza to La Serena

Every day, 6 buses from 1 bus companies leave Mendoza for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$95
Sunday 02/08
Monday 02/09
Tuesday 02/10
$95
Wednesday 02/11
Thursday 02/12
$95
Friday 02/13
Saturday 02/14
$95
Sunday 02/15
Monday 02/16
Tuesday 02/17
$95
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
$95
Sunday 02/22
Monday 02/23
Tuesday 02/24
$95
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

How to save money travelling from Mendoza to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mendoza to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mendoza to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mendoza to La Serena are also emptier.

All bus stations and stops in Mendoza and La Serena

In the map below, you can see where to find all bus stations in Mendoza and La Serena.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mendoza to La Serena? Compare all modes of transports from Mendoza to La Serena.

Service and Comfort on the bus from Mendoza to La Serena

Want to know which seat classes are available on the buses from Mendoza to La Serena? Or which bus companies serve the route Mendoza to La Serena? Below you will find answers to your questions.

FAQs about the Mendoza to La Serena bus

How much does a Mendoza La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $95 and takes 11h 45m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Mendoza to La Serena?

This route is offered by 1 companies with a range of ticket prices between $95 and $121. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Mendoza to La Serena each day?

Every day, the Mendoza to La Serena bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mendoza to La Serena take?

The fastest bus from Mendoza to La Serena is offered by CATA Internacional and takes 11h 45m. Bus tickets for this connection cost $95. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mendoza to La Serena?

The earliest bus arriving in La Serena from Mendoza starts at 8:15 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mendoza to La Serena?

The latest bus trip departing from Mendoza for La Serena starts at 8:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mendoza La Serena route?

When traveling by bus from Mendoza to La Serena, passengers can travel with CATA Internacional. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mendoza and La Serena?

You can check all the direct connections between Mendoza and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: CATA Internacional.

What can I take with me on the Mendoza to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mendoza La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mendoza La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mendoza to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Mendoza to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Mendoza and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mendoza to La Serena?

Prices and availability for 6 trips between Mendoza and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mendoza to La Serena

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

More bus routes to Mendoza and to La Serena

Here’s an overview of the most popular bus routes to Mendoza and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Mendoza from Corrientes Bus to Mendoza from Corrientes
Bus Venado Tuerto - Mendoza Bus Venado Tuerto - Mendoza
From Luján de Cuyo, MZ to Mendoza bus From Luján de Cuyo, MZ to Mendoza bus
Bus from Eugenio Bustos to Mendoza Bus from Eugenio Bustos to Mendoza
Bus Quilpué - La Serena Bus Quilpué - La Serena
Bus Iquique to La Serena Bus Iquique to La Serena
From Concepción to La Serena bus From Concepción to La Serena bus
From Valdivia to La Serena bus From Valdivia to La Serena bus
CheckMyBus › Buses in Argentina › Bus to Mendoza › Bus to La Serena

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