Compare all timetables for the bus from Mendoza to La Serena
Here is a selection of the cheapest bus trips from the schedule from Mendoza to La Serena from various bus operators like CATA Internacional for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CATA Internacional | 11h 45m | 8:15 PM | Mendoza | Bus Station | 8:00 AM | La Serena | Avda. Fco de Aguirre Station | Premium Economy | $99 |
A Bus from CATA Internacional goes from Bus Station, Mendoza (Argentina) at 3/28/2026 8:15:00 PM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 3/29/2026 8:00:00 AM. 50 Premium Economy ticket for $99 per person are available. Travel duration is 11h 45m
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Did you know that if you travel from Mendoza to La Serena via Santiago, RM, you can save more than $76? You can find the corresponding connections below.
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JBL Turismo16h 55m09:10 PMMendozaHotel Hyatt4:10 AMSantiago, RMSur Bus Station0BasicA Bus from JBL Turismo goes from Hotel Hyatt, Mendoza (Argentina) at 3/24/2026 9:10:00 PM to Sur Bus Station, Santiago, RM (Chile) arriving at 3/25/2026 4:10:00 AM. 50 Basic ticket for $12 per person are available. Travel duration is 7h 0m
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Turbus7h 10m06:55 AMSantiago, RMTerminal Alameda2:05 PMLa SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 3/25/2026 6:55:00 AM to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 3/25/2026 2:05:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 7h 10m
Waiting Time 2h 45mTravel time is 5h 10m longer, but you will save $76 -
Best Price Offer: The price for the cheapest bus from Mendoza to La Serena is $99 on 3/28/2026. Flexible travelers save on ticket prices.
Facts about the bus from Mendoza to La Serena
Compare all providers like CATA Internacional that travel 3 times every day by bus from Mendoza to La Serena in one click! Book your bus ticket from Mendoza to La Serena starting from $99!
| Cheapest Bus | $99 |
| Fastest Bus | 11h 45m |
| Earliest Bus | 8:15 PM |
| Latest Bus | 8:15 PM |
| Daily Bus Routes | 3 Ø |
| Distance | 250.5 miles |
| Bus Companies | CATA Internacional |
Cheapest bus connections from Mendoza to La Serena
Every day, 3 buses from 1 bus companies leave Mendoza for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
03/22
Monday
03/23
Tuesday
03/24
Wednesday
03/25
Thursday
03/26
Friday
03/27
Saturday
03/28
$99
Sunday
03/29
Monday
03/30
Tuesday
03/31
Wednesday
04/01
Thursday
04/02
Friday
04/03
Saturday
04/04
$99
Sunday
04/05
Monday
04/06
Tuesday
04/07
Wednesday
04/08
Thursday
04/09
Friday
04/10
Saturday
04/11
Sunday
04/12
Monday
04/13
Tuesday
04/14
Wednesday
04/15
Thursday
04/16
Friday
04/17
Saturday
04/18
How to save money travelling from Mendoza to La Serena
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Mendoza to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mendoza to La Serena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mendoza to La Serena are also emptier.All bus stations and stops in Mendoza and La Serena
In the map below, you can see where to find all bus stations in Mendoza and La Serena.
Compare the bus with other modes of transport
The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mendoza to La Serena? Compare all modes of transports from
Mendoza to La Serena.
Service and Comfort on the bus from Mendoza to La Serena
Want to know which seat classes are available on the buses from Mendoza to La Serena? Or which bus companies serve the route Mendoza to La Serena? Below you will find answers to your questions.
FAQs about the Mendoza to La Serena bus
How much does a Mendoza La Serena bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $99 and takes 11h 45m to reach La Serena. Compare offers to save money!
How much could I save by comparing buses from Mendoza to La Serena?
This route is offered by 1 companies with a range of ticket prices between $99 and $126. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.
On average, how many connections are available from Mendoza to La Serena each day?
Every day, the Mendoza to La Serena bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Mendoza to La Serena take?
The fastest bus from Mendoza to La Serena is offered by CATA Internacional and takes 11h 45m. Bus tickets for this connection cost $99. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Mendoza to La Serena?
The earliest bus arriving in La Serena from Mendoza starts at 8:15 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Mendoza to La Serena?
The latest bus trip departing from Mendoza for La Serena starts at 8:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Mendoza La Serena route?
When traveling by bus from Mendoza to La Serena, passengers can travel with CATA Internacional. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Mendoza and La Serena?
You can check all the direct connections between Mendoza and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: CATA Internacional.
What can I take with me on the Mendoza to La Serena bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mendoza La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Mendoza La Serena bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mendoza to La Serena on your planned travel date.
How does CheckMyBus find the best bus deals from Mendoza to La Serena?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Mendoza and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Mendoza to La Serena?
Prices and availability for 3 trips between Mendoza and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Mendoza to La Serena
Premium Economy
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Mendoza and to La Serena
Here’s an overview of the most popular bus routes to Mendoza and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Mendoza
- Buses to Mendoza from Bariloche
- Buses to Mendoza from Córdoba, CD
- Bus to Mendoza from Corrientes
- Bus from Eugenio Bustos to Mendoza
- From Luján de Cuyo, MZ to Mendoza bus
- Bus from Mar del Plata to Mendoza
- From Neuquén to Mendoza bus
- Bus to Mendoza from Potrerillos, MZ
- Bus to Mendoza from Rosario, SF
- Salta to Mendoza bus
- Bus San Juan, SJ - Mendoza
- Bus San Luis, SL to Mendoza
- San Miguel de Tucumán to Mendoza bus
- Bus San Rafael, MZ - Mendoza
- Buses Tunuyán, MZ - Mendoza
- From Valparaíso (CL) to Mendoza bus
- Bus Venado Tuerto - Mendoza
- Bus Routes to La Serena
- Buses to La Serena from Chillán
- From Concepción to La Serena bus
- Bus from Diego de Almagro to La Serena
- Bus Iquique to La Serena
- Bus Los Vilos to La Serena
- Pozo Almonte to La Serena bus
- Bus Quilpué - La Serena
- Bus Rancagua - La Serena
- Buses to La Serena from Salamanca, CO
- Buses from San Juan, SJ to La Serena
- Bus to La Serena from Sierra Gorda
- Bus Talca, ML to La Serena
- Buses to La Serena from Temuco
- From Valdivia to La Serena bus
- From Vallenar to La Serena bus
