Bus Santiago, RM to La Serena: Compare prices and save money

Compare all timetables for the bus from Santiago, RM to La Serena

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to La Serena from various bus operators like FlixBus, Cikbus Elité or Pullman Bus for the next days.

today

$17

tomorrow

$17

Monday

$16

Tuesday

$15

Wednesday

$15

Thursday

$15

Friday

$16

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Buses Romani	6h 30m	3:00 PM	Santiago, RM	Sur Bus Station	9:30 PM	La Serena	Central Bus Station	First Class	$17	A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 2/7/2026 3:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/7/2026 9:30:00 PM. 50 First Class ticket for $17 per person are available. Travel duration is 6h 30m
FlixBus	6h 45m	5:30 PM	Santiago, RM	Terminal San Borja	12:15 AM	La Serena	Central Bus Station	Economy	$18	A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 2/7/2026 5:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/8/2026 12:15:00 AM. 50 Economy ticket for $18 per person are available. Travel duration is 6h 45m
Serena Mar	7h 0m	10:00 AM	Santiago, RM	Terminal San Borja	5:00 PM	La Serena	Central Bus Station	First Class	$18	A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 2/7/2026 10:00:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/7/2026 5:00:00 PM. 50 First Class ticket for $18 per person are available. Travel duration is 7h 0m
Cormar Bus	6h 30m	10:55 PM	Santiago, RM	Terminal San Borja	5:25 AM	La Serena	Central Bus Station	Premium Economy	$19	A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/7/2026 10:55:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/8/2026 5:25:00 AM. 50 Premium Economy ticket for $19 per person are available. Travel duration is 6h 30m
Pullman Bus	6h 20m	11:00 AM	Santiago, RM	Terminal San Borja	5:20 PM	La Serena	El Sto, 1060	First Class	$21	A Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/7/2026 11:00:00 AM to El Sto, 1060, La Serena (Chile) arriving at 2/7/2026 5:20:00 PM. 50 First Class ticket for $21 per person are available. Travel duration is 6h 20m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	6h 50m	12:00 PM	Santiago, RM	Terminal San Borja	6:50 PM	La Serena	Central Bus Station	First Class	$17	A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/8/2026 12:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/8/2026 6:50:00 PM. 50 First Class ticket for $17 per person are available. Travel duration is 6h 50m
Buses Romani	6h 25m	5:30 PM	Santiago, RM	Sur Bus Station	11:55 PM	La Serena	Central Bus Station	Premium Economy	$17	A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 2/8/2026 5:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/8/2026 11:55:00 PM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 25m
FlixBus	6h 50m	4:45 PM	Santiago, RM	Terminal San Borja	11:35 PM	La Serena	Central Bus Station	Business	$21	A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 2/8/2026 4:45:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/8/2026 11:35:00 PM. 50 Business ticket for $21 per person are available. Travel duration is 6h 50m
Serena Mar	7h 0m	11:30 PM	Santiago, RM	Terminal San Borja	6:30 AM	La Serena	Central Bus Station	First Class	$21	A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 2/8/2026 11:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/9/2026 6:30:00 AM. 50 First Class ticket for $21 per person are available. Travel duration is 7h 0m
Pluss Chile	6h 30m	3:30 PM	Santiago, RM	Sur Bus Station	10:00 PM	La Serena	Central Bus Station	Premium Economy	$21	A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 2/8/2026 3:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/8/2026 10:00:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 30m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Pullman Bus	6h 30m	11:15 PM	Santiago, RM	Terminal San Borja	5:45 AM	La Serena	El Sto, 1060	First Class	$16	A Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/9/2026 11:15:00 PM to El Sto, 1060, La Serena (Chile) arriving at 2/10/2026 5:45:00 AM. 50 First Class ticket for $16 per person are available. Travel duration is 6h 30m
Cormar Bus	6h 10m	1:00 PM	Santiago, RM	Terminal San Borja	7:10 PM	La Serena	Central Bus Station	Premium Economy	$16	A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/9/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/9/2026 7:10:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 10m
FlixBus	6h 50m	4:45 PM	Santiago, RM	Terminal San Borja	11:35 PM	La Serena	Central Bus Station	Business	$18	A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 2/9/2026 4:45:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/9/2026 11:35:00 PM. 50 Business ticket for $18 per person are available. Travel duration is 6h 50m
Serena Mar	7h 0m	10:00 AM	Santiago, RM	Terminal San Borja	5:00 PM	La Serena	Central Bus Station	First Class	$18	A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 2/9/2026 10:00:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/9/2026 5:00:00 PM. 50 First Class ticket for $18 per person are available. Travel duration is 7h 0m
Buses Expreso Norte	6h 15m	1:00 PM	Santiago, RM	Terminal San Borja	7:15 PM	La Serena	Central Bus Station	First Class	$21	A Bus from Buses Expreso Norte goes from Terminal San Borja, Santiago, RM (Chile) at 2/9/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/9/2026 7:15:00 PM. 50 First Class ticket for $21 per person are available. Travel duration is 6h 15m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 45m	4:00 PM	Santiago, RM	Terminal San Borja	10:45 PM	La Serena	Central Bus Station	Economy	$15	A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 2/10/2026 4:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/10/2026 10:45:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 45m
Cormar Bus	6h 10m	1:00 PM	Santiago, RM	Terminal San Borja	7:10 PM	La Serena	Central Bus Station	Premium Economy	$16	A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/10/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/10/2026 7:10:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 10m
Serena Mar	7h 0m	10:00 AM	Santiago, RM	Terminal San Borja	5:00 PM	La Serena	Central Bus Station	First Class	$18	A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 2/10/2026 10:00:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/10/2026 5:00:00 PM. 50 First Class ticket for $18 per person are available. Travel duration is 7h 0m
Pluss Chile	6h 30m	10:00 AM	Santiago, RM	Sur Bus Station	4:30 PM	La Serena	Central Bus Station	Premium Economy	$21	A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 2/10/2026 10:00:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/10/2026 4:30:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 30m
Buses Expreso Norte	6h 15m	1:00 PM	Santiago, RM	Terminal San Borja	7:15 PM	La Serena	Central Bus Station	First Class	$21	A Bus from Buses Expreso Norte goes from Terminal San Borja, Santiago, RM (Chile) at 2/10/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/10/2026 7:15:00 PM. 50 First Class ticket for $21 per person are available. Travel duration is 6h 15m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 45m	3:00 PM	Santiago, RM	Terminal San Borja	9:45 PM	La Serena	Central Bus Station	Business	$15	A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 2/11/2026 3:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/11/2026 9:45:00 PM. 50 Business ticket for $15 per person are available. Travel duration is 6h 45m
Cormar Bus	6h 10m	1:00 PM	Santiago, RM	Terminal San Borja	7:10 PM	La Serena	Central Bus Station	Premium Economy	$16	A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/11/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/11/2026 7:10:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 10m
Pluss Chile	6h 20m	7:45 AM	Santiago, RM	Sur Bus Station	2:05 PM	La Serena	Central Bus Station	Premium Economy	$21	A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 2/11/2026 7:45:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/11/2026 2:05:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 20m
Buses Expreso Norte	6h 15m	1:00 PM	Santiago, RM	Terminal San Borja	7:15 PM	La Serena	Central Bus Station	First Class	$21	A Bus from Buses Expreso Norte goes from Terminal San Borja, Santiago, RM (Chile) at 2/11/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/11/2026 7:15:00 PM. 50 First Class ticket for $21 per person are available. Travel duration is 6h 15m
Buses Romani	6h 30m	1:30 PM	Santiago, RM	Terminal San Borja	8:00 PM	La Serena	Central Bus Station	Business	$22	A Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 2/11/2026 1:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/11/2026 8:00:00 PM. 50 Business ticket for $22 per person are available. Travel duration is 6h 30m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 10m	2:15 PM	Santiago, RM	Terminal San Borja	8:25 PM	La Serena	Central Bus Station	Economy	$15	A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 2/12/2026 2:15:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/12/2026 8:25:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 10m
Cormar Bus	6h 10m	1:00 PM	Santiago, RM	Terminal San Borja	7:10 PM	La Serena	Central Bus Station	Premium Economy	$16	A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/12/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/12/2026 7:10:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 10m
Serena Mar	7h 0m	10:00 AM	Santiago, RM	Terminal San Borja	5:00 PM	La Serena	Central Bus Station	First Class	$18	A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 2/12/2026 10:00:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/12/2026 5:00:00 PM. 50 First Class ticket for $18 per person are available. Travel duration is 7h 0m
Buses Expreso Norte	6h 15m	1:00 PM	Santiago, RM	Terminal San Borja	7:15 PM	La Serena	Central Bus Station	First Class	$21	A Bus from Buses Expreso Norte goes from Terminal San Borja, Santiago, RM (Chile) at 2/12/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/12/2026 7:15:00 PM. 50 First Class ticket for $21 per person are available. Travel duration is 6h 15m
Pluss Chile	6h 20m	7:45 AM	Santiago, RM	Sur Bus Station	2:05 PM	La Serena	Central Bus Station	Premium Economy	$21	A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 2/12/2026 7:45:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/12/2026 2:05:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 20m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Cormar Bus	6h 30m	5:30 PM	Santiago, RM	Terminal San Borja	12:00 AM	La Serena	Central Bus Station	Premium Economy	$16	A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 2/13/2026 5:30:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/14/2026 12:00:00 AM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 30m
FlixBus	6h 45m	3:00 PM	Santiago, RM	Terminal San Borja	9:45 PM	La Serena	Central Bus Station	Business	$17	A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 2/13/2026 3:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/13/2026 9:45:00 PM. 50 Business ticket for $17 per person are available. Travel duration is 6h 45m
Serena Mar	7h 0m	10:00 AM	Santiago, RM	Terminal San Borja	5:00 PM	La Serena	Central Bus Station	First Class	$18	A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 2/13/2026 10:00:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/13/2026 5:00:00 PM. 50 First Class ticket for $18 per person are available. Travel duration is 7h 0m
Buses Expreso Norte	6h 15m	1:00 PM	Santiago, RM	Terminal San Borja	7:15 PM	La Serena	Central Bus Station	First Class	$21	A Bus from Buses Expreso Norte goes from Terminal San Borja, Santiago, RM (Chile) at 2/13/2026 1:00:00 PM to Central Bus Station, La Serena (Chile) arriving at 2/13/2026 7:15:00 PM. 50 First Class ticket for $21 per person are available. Travel duration is 6h 15m
Pluss Chile	6h 20m	7:45 AM	Santiago, RM	Sur Bus Station	2:05 PM	La Serena	Central Bus Station	Premium Economy	$21	A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 2/13/2026 7:45:00 AM to Central Bus Station, La Serena (Chile) arriving at 2/13/2026 2:05:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 20m

Best Price Offer: The price for the cheapest bus from Santiago, RM to La Serena is $13 on 2/24/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santiago, RM and La Serena

See here how frequent the connections between Santiago, RM and La Serena are, during different times and days of the week.

Friday is the busiest day, with more than 395 daily buses from Santiago, RM to La Serena. Saturday has instead the fewest connections, with only 313 daily coaches between Santiago, RM and La Serena.

The busiest time of the day is the Evening, with 1056 buses from Santiago, RM to La Serena, while Night sees the fewest connections between Santiago, RM and La Serena, with 14 offers.

Facts about the bus from Santiago, RM to La Serena

Compare all providers like FlixBus, Cikbus Elité and Pullman Bus that travel 358 times every day by bus from Santiago, RM to La Serena in one click! Book your bus ticket from Santiago, RM to La Serena starting from $13!

Cheapest Bus	$13
Fastest Bus	5h 30m
Earliest Bus	1:30 AM
Latest Bus	11:59 PM
Daily Bus Routes	358 Ø
Distance	247.0 miles
Bus Companies	FlixBus, Cikbus Elité, Pullman Bus, Turbus, Pullman San Andres, Pluss Chile, Condor Bus, Cormar Bus, Buses Romani, Nueva Andimar Vip and 5 more.

Cheapest bus connections from Santiago, RM to La Serena

Every day, 358 buses from 15 bus companies leave Santiago, RM for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

$19

Sunday 02/08

$21

Monday 02/09

$18

Tuesday 02/10

$21

Wednesday 02/11

$15

Thursday 02/12

$16

Friday 02/13

$17

Saturday 02/14

$15

Sunday 02/15

$22

Monday 02/16

$15

Tuesday 02/17

$13

Wednesday 02/18

$13

Thursday 02/19

$13

Friday 02/20

$15

Saturday 02/21

$20

Sunday 02/22

$15

Monday 02/23

$13

Tuesday 02/24

$13

Wednesday 02/25

$13

Thursday 02/26

$16

Friday 02/27

$21

Saturday 02/28

The cheapest time to travel from Santiago, RM to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to La Serena, for the next 30 days.

With a price starting from $11, Tuesday is the cheapest day for a bus from Santiago, RM to La Serena. Friday instead is the most expensive day with prices starting from $15.

Night is the cheapest day time for bus tickets from Santiago, RM to La Serena, with $11. Morning is the most expensive time of the day with prices starting from $16.

How to save money travelling from Santiago, RM to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago, RM to La Serena are also emptier.

Beloved bus companies from Santiago, RM to La Serena

These are the most booked bus companies between Santiago, RM to La Serena from our users.

FlixBus from Santiago, RM to La Serena

Here you will find the key facts about the FlixBus bus route Santiago, RM to La Serena:

Cheapest Price	$15
Fastest Bus	5h 35m
Earliest Bus	6:15 AM
Last Bus	11:59 PM
Daily Connections	77 Ø
Found on	2/6/2026

Nueva Andimar Vip from Santiago, RM to La Serena

Here you will find the key facts about the Nueva Andimar Vip bus route Santiago, RM to La Serena:

Cheapest Price	$23
Fastest Bus	6h 0m
Earliest Bus	7:50 AM
Last Bus	11:30 PM
Daily Connections	13 Ø
Found on	2/6/2026

Buses Romani from Santiago, RM to La Serena

Here you will find the key facts about the Buses Romani bus route Santiago, RM to La Serena:

Cheapest Price	$17
Fastest Bus	5h 45m
Earliest Bus	11:30 AM
Last Bus	11:40 PM
Daily Connections	15 Ø
Found on	2/7/2026

Latest reviews for bus companies on the route Santiago, RM - La Serena

jonathan, 9/4/2025

HORRIBLE

Rocío Santana , 11/22/2024

Malísima experiencia con un hombre del personal, a media hora de haber salido del terminal San Borja mi hija necesito usar el baño a lo que respondió que el baño era solo para ruta y que estaban aburr ... Malísima experiencia con un hombre del personal, a media hora de haber salido del terminal San Borja mi hija necesito usar el baño a lo que respondió que el baño era solo para ruta y que estaban aburridos que las personas le hicieran ( del 2) , cosa que entiendo perfectamente, pero fue bastante grosero y retador y con la voz alzada, pésima experiencia no respondí porque estaba con mi hija pero nunca más usaré este servicio.

Camila , 11/7/2024

Pésima experiencia, en bus de verdad tienen un olor demasiado hediondo es insoportable, además no tienen aire acondicionado y hizo mucho frío yo viaje de noche y pase demasiado frío, gente del bus le ... Pésima experiencia, en bus de verdad tienen un olor demasiado hediondo es insoportable, además no tienen aire acondicionado y hizo mucho frío yo viaje de noche y pase demasiado frío, gente del bus le pidió al chofer copiloto subir la temperatura y jamás lo hizo La verdad nunca mas viajo con ellos

Ernesto, 9/12/2024

Viajo regularmente entre Santiago y La Serena y v/v, en Buses salón cama. es la primera vez que tomo esta empresa y en realidad no volvería a tomarla. Las razones: GPS DESCONECTADO por tanto se DESC ... Viajo regularmente entre Santiago y La Serena y v/v, en Buses salón cama. es la primera vez que tomo esta empresa y en realidad no volvería a tomarla. Las razones: GPS DESCONECTADO por tanto se DESCONOCE el nombre del conductor, cuanto tiempo lleva conduciendo y a qué velocidad estamos transitando. Maquina NO SANITIZADA da desconfianza sentarse en los asientos con los apoyacabezas negros de suciedad y sin funda de protección lo mismo pasa con los cinturones de seguridad también muy sucios. Esta máquina salió a las 12:30 PM desde terminal San Borja con destino a Arica, (yo bajo el La Serena)

Sramirez , 9/12/2024

Voy viajando en Salón cama y literal que voy atrapada entre mi asiento y el respaldo del asiento en frente de mi. El nivel de inclinación de los asientos supera lo permitido quedando prácticamente atr ... Voy viajando en Salón cama y literal que voy atrapada entre mi asiento y el respaldo del asiento en frente de mi. El nivel de inclinación de los asientos supera lo permitido quedando prácticamente atrapada, tienes el respaldo de la persona que va delante sobre tus piernas sin poder moverte y eso que soy delgada, imagino a alguien de mayor dimensión o un adulto mayor, además del mal olor en el bus es horrible. No viajo más en esta línea.

All bus stations and stops in Santiago, RM and La Serena

In the map below, you can see where to find all bus stations in Santiago, RM and La Serena.

Sur Bus Station

Av Libertador Bernardo O'Higgins 3850

Terminal San Borja

San Francisco de Borja 198-180

Terminal Alameda

Av Libertador Bernardo O'Higgins 3750

Terminal Pajaritos

Av. Gral. Óscar Bonilla 5935-5939

Los Héroes Station

Tucapel Jiménez 22

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Bus Station

Avenida El Santo 1475

El Sto, 1060

terminal de buses covalle bus

Rotonda

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago, RM to La Serena? Compare all modes of transports from Santiago, RM to La Serena.

Service and Comfort on the bus from Santiago, RM to La Serena

Want to know which seat classes are available on the buses from Santiago, RM to La Serena? Or which bus companies serve the route Santiago, RM to La Serena? Below you will find answers to your questions.

FAQs about the Santiago, RM to La Serena bus

How much does a Santiago, RM La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $13 and takes 6h 45m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Santiago, RM to La Serena?

This route is offered by 15 companies with a range of ticket prices between $13 and $94. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Santiago, RM to La Serena each day?

Every day, the Santiago, RM to La Serena bus route is served by approximately 358 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago, RM to La Serena take?

The fastest bus from Santiago, RM to La Serena is offered by Turbus and takes 5h 30m. Bus tickets for this connection cost $42. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago, RM to La Serena?

The earliest bus arriving in La Serena from Santiago, RM starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago, RM to La Serena?

The latest bus trip departing from Santiago, RM for La Serena starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago, RM La Serena route?

When traveling by bus from Santiago, RM to La Serena, passengers can travel with FlixBus, Cikbus Elité and Pullman Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago, RM and La Serena?

You can check all the direct connections between Santiago, RM and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Cikbus Elité and Pullman Bus.

What can I take with me on the Santiago, RM to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago, RM La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago, RM to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 358 daily trips between Santiago, RM and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago, RM to La Serena?

Prices and availability for 358 trips between Santiago, RM and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago, RM to La Serena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to La Serena

Here’s an overview of the most popular bus routes to Santiago, RM and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!